Bacillus Calmette-Guérin vaccine, antimalarial, age and gender relation to COVID-19 spread and mortality.
Identifieur interne : 001169 ( Main/Corpus ); précédent : 001168; suivant : 001170Bacillus Calmette-Guérin vaccine, antimalarial, age and gender relation to COVID-19 spread and mortality.
Auteurs : Ahmed Osama El-Gendy ; Haitham Saeed ; Ahmed M A. Ali ; Hossam M. Zawbaa ; Dina Gomaa ; Hadeer S. Harb ; Yasmin M. Madney ; Hasnaa Osama ; Mona A. Abdelrahman ; Mohamed E A. AbdelrahimSource :
- Vaccine [ 1873-2518 ] ; 2020.
English descriptors
- KwdEn :
- Aging (MeSH), Antiviral Agents (pharmacology), Antiviral Agents (therapeutic use), BCG Vaccine (immunology), COVID-19 (MeSH), Chemoprevention (MeSH), Chloroquine (pharmacology), Chloroquine (therapeutic use), Coronavirus Infections (immunology), Coronavirus Infections (mortality), Coronavirus Infections (prevention & control), Coronavirus Infections (transmission), Disease Susceptibility (immunology), Female (MeSH), Geographic Mapping (MeSH), Humans (MeSH), Hydroxychloroquine (pharmacology), Hydroxychloroquine (therapeutic use), Infant (MeSH), Internationality (MeSH), Male (MeSH), Pandemics (prevention & control), Pneumonia, Viral (immunology), Pneumonia, Viral (mortality), Pneumonia, Viral (prevention & control), Pneumonia, Viral (transmission), Sex Characteristics (MeSH).
- MESH :
- chemical , immunology : BCG Vaccine.
- chemical , pharmacology : Antiviral Agents, Chloroquine, Hydroxychloroquine.
- chemical , therapeutic use : Antiviral Agents, Chloroquine, Hydroxychloroquine.
- immunology : Coronavirus Infections, Disease Susceptibility, Pneumonia, Viral.
- mortality : Coronavirus Infections, Pneumonia, Viral.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- Aging, COVID-19, Chemoprevention, Female, Geographic Mapping, Humans, Infant, Internationality, Male, Sex Characteristics.
Abstract
COVID-19 is affecting different countries all over the world with great variation in infection rate and death ratio. Some reports suggested a relation between the Bacillus Calmette-Guérin (BCG) vaccine and the malaria treatment to the prevention of SARS-CoV-2 infection. Some reports related infant's lower susceptibility to the COVID-19. Some other reports a higher risk in males compared to females in such COVID-19 pandemic. Also, some other reports claimed the possible use of chloroquine and hydroxychloroquine as prophylactic in such a pandemic. The present commentary is to discuss the possible relation between those factors and SARS-CoV-2 infection.
DOI: 10.1016/j.vaccine.2020.06.083
PubMed: 32654907
PubMed Central: PMC7332946
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Ali</name><affiliation><nlm:affiliation>Pharmaceutics Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; Pharmaceutics Department, Faculty of Pharmacy, Taif University, Taif, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Zawbaa, Hossam M" sort="Zawbaa, Hossam M" uniqKey="Zawbaa H" first="Hossam M" last="Zawbaa">Hossam M. Zawbaa</name><affiliation><nlm:affiliation>Faculty of Computers and Artificial Intelligence, Beni-Suef University.</nlm:affiliation></affiliation></author><author><name sortKey="Gomaa, Dina" sort="Gomaa, Dina" uniqKey="Gomaa D" first="Dina" last="Gomaa">Dina Gomaa</name><affiliation><nlm:affiliation>Egyptian Drug authority, Cairo, Egypt; RAMEDA pharmaceuticals, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Harb, Hadeer S" sort="Harb, Hadeer S" uniqKey="Harb H" first="Hadeer S" last="Harb">Hadeer S. Harb</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Madney, Yasmin M" sort="Madney, Yasmin M" uniqKey="Madney Y" first="Yasmin M" last="Madney">Yasmin M. Madney</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Osama, Hasnaa" sort="Osama, Hasnaa" uniqKey="Osama H" first="Hasnaa" last="Osama">Hasnaa Osama</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Abdelrahman, Mona A" sort="Abdelrahman, Mona A" uniqKey="Abdelrahman M" first="Mona A" last="Abdelrahman">Mona A. Abdelrahman</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Abdelrahim, Mohamed E A" sort="Abdelrahim, Mohamed E A" uniqKey="Abdelrahim M" first="Mohamed E A" last="Abdelrahim">Mohamed E A. Abdelrahim</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. Electronic address: mohamedemam9@yahoo.com.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32654907</idno><idno type="pmid">32654907</idno><idno type="doi">10.1016/j.vaccine.2020.06.083</idno><idno type="pmc">PMC7332946</idno><idno type="wicri:Area/Main/Corpus">001169</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001169</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Bacillus Calmette-Guérin vaccine, antimalarial, age and gender relation to COVID-19 spread and mortality.</title><author><name sortKey="Osama El Gendy, Ahmed" sort="Osama El Gendy, Ahmed" uniqKey="Osama El Gendy A" first="Ahmed" last="Osama El-Gendy">Ahmed Osama El-Gendy</name><affiliation><nlm:affiliation>Microbiology and Immunology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Saeed, Haitham" sort="Saeed, Haitham" uniqKey="Saeed H" first="Haitham" last="Saeed">Haitham Saeed</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Ali, Ahmed M A" sort="Ali, Ahmed M A" uniqKey="Ali A" first="Ahmed M A" last="Ali">Ahmed M A. Ali</name><affiliation><nlm:affiliation>Pharmaceutics Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; Pharmaceutics Department, Faculty of Pharmacy, Taif University, Taif, Saudi Arabia.</nlm:affiliation></affiliation></author><author><name sortKey="Zawbaa, Hossam M" sort="Zawbaa, Hossam M" uniqKey="Zawbaa H" first="Hossam M" last="Zawbaa">Hossam M. Zawbaa</name><affiliation><nlm:affiliation>Faculty of Computers and Artificial Intelligence, Beni-Suef University.</nlm:affiliation></affiliation></author><author><name sortKey="Gomaa, Dina" sort="Gomaa, Dina" uniqKey="Gomaa D" first="Dina" last="Gomaa">Dina Gomaa</name><affiliation><nlm:affiliation>Egyptian Drug authority, Cairo, Egypt; RAMEDA pharmaceuticals, Cairo, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Harb, Hadeer S" sort="Harb, Hadeer S" uniqKey="Harb H" first="Hadeer S" last="Harb">Hadeer S. Harb</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Madney, Yasmin M" sort="Madney, Yasmin M" uniqKey="Madney Y" first="Yasmin M" last="Madney">Yasmin M. Madney</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Osama, Hasnaa" sort="Osama, Hasnaa" uniqKey="Osama H" first="Hasnaa" last="Osama">Hasnaa Osama</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Abdelrahman, Mona A" sort="Abdelrahman, Mona A" uniqKey="Abdelrahman M" first="Mona A" last="Abdelrahman">Mona A. Abdelrahman</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</nlm:affiliation></affiliation></author><author><name sortKey="Abdelrahim, Mohamed E A" sort="Abdelrahim, Mohamed E A" uniqKey="Abdelrahim M" first="Mohamed E A" last="Abdelrahim">Mohamed E A. Abdelrahim</name><affiliation><nlm:affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. Electronic address: mohamedemam9@yahoo.com.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Vaccine</title><idno type="eISSN">1873-2518</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aging (MeSH)</term><term>Antiviral Agents (pharmacology)</term><term>Antiviral Agents (therapeutic use)</term><term>BCG Vaccine (immunology)</term><term>COVID-19 (MeSH)</term><term>Chemoprevention (MeSH)</term><term>Chloroquine (pharmacology)</term><term>Chloroquine (therapeutic use)</term><term>Coronavirus Infections (immunology)</term><term>Coronavirus Infections (mortality)</term><term>Coronavirus Infections (prevention & control)</term><term>Coronavirus Infections (transmission)</term><term>Disease Susceptibility (immunology)</term><term>Female (MeSH)</term><term>Geographic Mapping (MeSH)</term><term>Humans (MeSH)</term><term>Hydroxychloroquine (pharmacology)</term><term>Hydroxychloroquine (therapeutic use)</term><term>Infant (MeSH)</term><term>Internationality (MeSH)</term><term>Male (MeSH)</term><term>Pandemics (prevention & control)</term><term>Pneumonia, Viral (immunology)</term><term>Pneumonia, Viral (mortality)</term><term>Pneumonia, Viral (prevention & control)</term><term>Pneumonia, Viral (transmission)</term><term>Sex Characteristics (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>BCG Vaccine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antiviral Agents</term><term>Chloroquine</term><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Chloroquine</term><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus Infections</term><term>Disease Susceptibility</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Coronavirus Infections</term><term>Pandemics</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aging</term><term>COVID-19</term><term>Chemoprevention</term><term>Female</term><term>Geographic Mapping</term><term>Humans</term><term>Infant</term><term>Internationality</term><term>Male</term><term>Sex Characteristics</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">COVID-19 is affecting different countries all over the world with great variation in infection rate and death ratio. Some reports suggested a relation between the Bacillus Calmette-Guérin (BCG) vaccine and the malaria treatment to the prevention of SARS-CoV-2 infection. Some reports related infant's lower susceptibility to the COVID-19. Some other reports a higher risk in males compared to females in such COVID-19 pandemic. Also, some other reports claimed the possible use of chloroquine and hydroxychloroquine as prophylactic in such a pandemic. The present commentary is to discuss the possible relation between those factors and SARS-CoV-2 infection.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32654907</PMID><DateCompleted><Year>2020</Year><Month>07</Month><Day>27</Day></DateCompleted><DateRevised><Year>2021</Year><Month>01</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-2518</ISSN><JournalIssue CitedMedium="Internet"><Volume>38</Volume><Issue>35</Issue><PubDate><Year>2020</Year><Month>07</Month><Day>31</Day></PubDate></JournalIssue><Title>Vaccine</Title><ISOAbbreviation>Vaccine</ISOAbbreviation></Journal><ArticleTitle>Bacillus Calmette-Guérin vaccine, antimalarial, age and gender relation to COVID-19 spread and mortality.</ArticleTitle><Pagination><MedlinePgn>5564-5568</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0264-410X(20)30886-0</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.vaccine.2020.06.083</ELocationID><Abstract><AbstractText>COVID-19 is affecting different countries all over the world with great variation in infection rate and death ratio. Some reports suggested a relation between the Bacillus Calmette-Guérin (BCG) vaccine and the malaria treatment to the prevention of SARS-CoV-2 infection. Some reports related infant's lower susceptibility to the COVID-19. Some other reports a higher risk in males compared to females in such COVID-19 pandemic. Also, some other reports claimed the possible use of chloroquine and hydroxychloroquine as prophylactic in such a pandemic. The present commentary is to discuss the possible relation between those factors and SARS-CoV-2 infection.</AbstractText><CopyrightInformation>Copyright © 2020 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Osama El-Gendy</LastName><ForeName>Ahmed</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Microbiology and Immunology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saeed</LastName><ForeName>Haitham</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ali</LastName><ForeName>Ahmed M A</ForeName><Initials>AMA</Initials><AffiliationInfo><Affiliation>Pharmaceutics Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; Pharmaceutics Department, Faculty of Pharmacy, Taif University, Taif, Saudi Arabia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zawbaa</LastName><ForeName>Hossam M</ForeName><Initials>HM</Initials><AffiliationInfo><Affiliation>Faculty of Computers and Artificial Intelligence, Beni-Suef University.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gomaa</LastName><ForeName>Dina</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Egyptian Drug authority, Cairo, Egypt; RAMEDA pharmaceuticals, Cairo, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Harb</LastName><ForeName>Hadeer S</ForeName><Initials>HS</Initials><AffiliationInfo><Affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Madney</LastName><ForeName>Yasmin M</ForeName><Initials>YM</Initials><AffiliationInfo><Affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Osama</LastName><ForeName>Hasnaa</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abdelrahman</LastName><ForeName>Mona A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abdelrahim</LastName><ForeName>Mohamed E A</ForeName><Initials>MEA</Initials><AffiliationInfo><Affiliation>Clinical Pharmacy Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt. Electronic address: mohamedemam9@yahoo.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>07</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Vaccine</MedlineTA><NlmUniqueID>8406899</NlmUniqueID><ISSNLinking>0264-410X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001500">BCG Vaccine</NameOfSubstance></Chemical><Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber><NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance></Chemical><Chemical><RegistryNumber>886U3H6UFF</RegistryNumber><NameOfSubstance UI="D002738">Chloroquine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000375" MajorTopicYN="Y">Aging</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001500" MajorTopicYN="N">BCG Vaccine</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018890" MajorTopicYN="Y">Chemoprevention</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002738" MajorTopicYN="N">Chloroquine</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004198" MajorTopicYN="N">Disease Susceptibility</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062305" MajorTopicYN="N">Geographic Mapping</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D038622" MajorTopicYN="N">Internationality</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012727" MajorTopicYN="Y">Sex Characteristics</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Age</Keyword><Keyword MajorTopicYN="Y">Antimalarial</Keyword><Keyword MajorTopicYN="Y">BCG</Keyword><Keyword MajorTopicYN="Y">COVID 19</Keyword><Keyword MajorTopicYN="Y">Gender</Keyword></KeywordList><CoiStatement>Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>04</Month><Day>11</Day></PubMedPubDate><PubMedPubDate 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