CovidChloroV1, Main, Corpus, bibRecord, 001029

A Perspective on Emerging Therapeutic Interventions for COVID-19.

Identifieur interne : 001029 ( Main/Corpus ); précédent : 001028; suivant : 001030

A Perspective on Emerging Therapeutic Interventions for COVID-19.

Auteurs : Muhammad Torequl Islam ; Md Nasiruddin ; Ishaq N. Khan ; Siddhartha Kumar Mishra ; Md Kudrat-E-Zahan ; Thoufiqul Alam Riaz ; Eunus S. Ali ; M Safiur Rahman ; Mohammad S. Mubarak ; Miquel Martorell ; William C. Cho ; Daniela Calina ; Anca Oana Docea ; Javad Sharifi-Rad

Source :

Frontiers in public health [ 2296-2565 ] ; 2020.

RBID : pubmed:32733837

English descriptors

KwdEn :
- Adenosine Monophosphate (analogs & derivatives), Adenosine Monophosphate (therapeutic use), Alanine (analogs & derivatives), Alanine (therapeutic use), Antimalarials (therapeutic use), Antiviral Agents (therapeutic use), COVID-19 (physiopathology), COVID-19 (therapy), COVID-19 (transmission), Humans (MeSH), Hydroxychloroquine (therapeutic use), Public Health (MeSH), Vaccines (MeSH), Virus Replication (MeSH).
MESH :
- chemical , analogs & derivatives : Adenosine Monophosphate, Alanine.
- chemical , therapeutic use : Adenosine Monophosphate, Alanine, Antimalarials, Antiviral Agents, Hydroxychloroquine.
- physiopathology : COVID-19.
- therapy : COVID-19.
- transmission : COVID-19.
- Humans, Public Health, Vaccines, Virus Replication.

Abstract

Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.

DOI: 10.3389/fpubh.2020.00281
PubMed: 32733837
PubMed Central: PMC7362761

Links to Exploration step

pubmed:32733837

Le document en format XML

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<author><name sortKey="Mubarak, Mohammad S" sort="Mubarak, Mohammad S" uniqKey="Mubarak M" first="Mohammad S" last="Mubarak">Mohammad S. Mubarak</name>
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<affiliation><nlm:affiliation>Centre for Healthy Living, University of Concepción, Concepción, Chile.</nlm:affiliation>
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<author><name sortKey="Cho, William C" sort="Cho, William C" uniqKey="Cho W" first="William C" last="Cho">William C. Cho</name>
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</affiliation>
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<author><name sortKey="Docea, Anca Oana" sort="Docea, Anca Oana" uniqKey="Docea A" first="Anca Oana" last="Docea">Anca Oana Docea</name>
<affiliation><nlm:affiliation>Department of Toxicology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Sharifi Rad, Javad" sort="Sharifi Rad, Javad" uniqKey="Sharifi Rad J" first="Javad" last="Sharifi-Rad">Javad Sharifi-Rad</name>
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<series><title level="j">Frontiers in public health</title>
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<term>COVID-19 (therapy)</term>
<term>COVID-19 (transmission)</term>
<term>Humans (MeSH)</term>
<term>Hydroxychloroquine (therapeutic use)</term>
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<front><div type="abstract" xml:lang="en">Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.</div>
</front>
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<Abstract><AbstractText>Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by club-like spikes that protrude from their surface. An outbreak of a novel coronavirus 2019 infection has posed significant threat to the health and economies in the whole world. This article reviewed the viral replication, pathogenicity, prevention and treatment strategies. With a lack of approved treatment options for this virus, alternative approaches to control the spread of disease is in urgent need. This article also covers some management strategies which may be applied to this virus outbreak. Ongoing clinical studies related to possible treatments for COVID-19, potential vaccines, and alternative medication such as natural compounds are also discussed.</AbstractText>
<CopyrightInformation>Copyright © 2020 Torequl Islam, Nasiruddin, Khan, Mishra, Kudrat-E-Zahan, Alam Riaz, Ali, Rahman, Mubarak, Martorell, Cho, Calina, Docea and Sharifi-Rad.</CopyrightInformation>
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<ForeName>Muhammad</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Nasiruddin</LastName>
<ForeName>Md</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Chemistry, Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj, Bangladesh.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Khan</LastName>
<ForeName>Ishaq N</ForeName>
<Initials>IN</Initials>
<AffiliationInfo><Affiliation>Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mishra</LastName>
<ForeName>Siddhartha Kumar</ForeName>
<Initials>SK</Initials>
<AffiliationInfo><Affiliation>Cancer Biology Laboratory, Department of Zoology, School of Biological Sciences, Dr. Harisingh Gour Central University, Sagar, India.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Kudrat-E-Zahan</LastName>
<ForeName>Md</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Alam Riaz</LastName>
<ForeName>Thoufiqul</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Pharmacology, School of Medicine, Institute of New Drug Development, Jeonbuk National University, Jeonju, South Korea.</Affiliation>
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<ForeName>Eunus S</ForeName>
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<AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Rahman</LastName>
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</AffiliationInfo>
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<ForeName>Mohammad S</ForeName>
<Initials>MS</Initials>
<AffiliationInfo><Affiliation>Department of Chemistry, The University of Jordan, Amman, Jordan.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Martorell</LastName>
<ForeName>Miquel</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion, Chile.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Centre for Healthy Living, University of Concepción, Concepción, Chile.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cho</LastName>
<ForeName>William C</ForeName>
<Initials>WC</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Calina</LastName>
<ForeName>Daniela</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, Romania.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Docea</LastName>
<ForeName>Anca Oana</ForeName>
<Initials>AO</Initials>
<AffiliationInfo><Affiliation>Department of Toxicology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sharifi-Rad</LastName>
<ForeName>Javad</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</Affiliation>
</AffiliationInfo>
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A Perspective on Emerging Therapeutic Interventions for COVID-19.

A Perspective on Emerging Therapeutic Interventions for COVID-19.

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