Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh.
Identifieur interne : 001001 ( Main/Corpus ); précédent : 001000; suivant : 001002Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh.
Auteurs : Muhammad Ar Bhuyan ; Mamun Al Mahtab ; Eshita Ashab ; Md Jahirul Haque ; Syed Md M. Hoque ; Akm Faizul Huq ; Md Atikul Islam ; Nuzhat Choudhury ; Reema A. Alia ; Musarrat Mahtab ; Md Sakirul I. Khan ; Sheikh Mf AkbarSource :
- Euroasian journal of hepato-gastroenterology [ 2231-5047 ]
Abstract
Background and aim
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has induced a sense of panic around the world as the disease is highly contagious and has been spreading in full swing during last 5 months causing millions of COVID-19 patients and hundreds of thousands of deaths. Bangladesh, a country of 170 million people, is not an exception regarding COVID-19; it has reported several thousand COVID-19 patients with several hundred of deaths. This observational study has been planned to assess the scope and limitation of management strategy against COVID-19 patients in a medical college hospital of Bangladesh with available drugs in a real-life situation.
Materials and methods
All patients in this cohort (
Results
Out of total 33 patients, 1 patient died at day 4 day after admission. Two patients developed severe complications and were referred to tertiary hospital in Dhaka (2 and 3 days after admission), the capital of Bangladesh, where they recovered and were discharged from hospital after being SARS-CoV-2 negative. The rest 30 patients were discharged from the medical college hospital after being negative for SARS-CoV-2 in two subsequent assessments and improvement of their COVID-related symptoms. The average hospital stay of these patients was 14.5 days with a range of 10-24 days.
Conclusion
It seems that most of the COVID-19 patients may be adequately managed by standard of care management with drug support. However, early diagnosis and hospitalization with adequate care may be important variables for better survival. These factors may be properly ensured if the patient burden remains at a palatable level in forthcoming days in Bangladesh.
How to cite this article
Bhuyan MAR, Al Mahtab M, Ashab E,
DOI: 10.5005/jp-journals-10018-1317
PubMed: 32742969
PubMed Central: PMC7376594
Links to Exploration step
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Hoque</name><affiliation><nlm:affiliation>Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Faizul Huq, Akm" sort="Faizul Huq, Akm" uniqKey="Faizul Huq A" first="Akm" last="Faizul Huq">Akm Faizul Huq</name><affiliation><nlm:affiliation>Department of Medicine, Combined Military Hospital, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Islam, Md Atikul" sort="Islam, Md Atikul" uniqKey="Islam M" first="Md Atikul" last="Islam">Md Atikul Islam</name><affiliation><nlm:affiliation>Department of Medical Gastroenterology, Sheikh Russel Gastroliver Institute and Hospital, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Choudhury, Nuzhat" sort="Choudhury, Nuzhat" uniqKey="Choudhury N" first="Nuzhat" last="Choudhury">Nuzhat Choudhury</name><affiliation><nlm:affiliation>Department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Alia, Reema A" sort="Alia, Reema A" uniqKey="Alia R" first="Reema A" last="Alia">Reema A. Alia</name><affiliation><nlm:affiliation>Department of Paediatrics, Uttara Adhunik Medical College, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Mahtab, Musarrat" sort="Mahtab, Musarrat" uniqKey="Mahtab M" first="Musarrat" last="Mahtab">Musarrat Mahtab</name><affiliation><nlm:affiliation>Department of Biochemistry and Biotechnology, North South University, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Khan, Md Sakirul I" sort="Khan, Md Sakirul I" uniqKey="Khan M" first="Md Sakirul I" last="Khan">Md Sakirul I. Khan</name><affiliation><nlm:affiliation>Department of Anatomy and Embryology, Ehime University Graduate School of Medicine, Ehime, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Akbar, Sheikh Mf" sort="Akbar, Sheikh Mf" uniqKey="Akbar S" first="Sheikh Mf" last="Akbar">Sheikh Mf Akbar</name><affiliation><nlm:affiliation>Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan; Miyakawa Memorial Research Foundation, Tokyo, Japan.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020 Jan-Jun</date><idno type="RBID">pubmed:32742969</idno><idno type="pmid">32742969</idno><idno type="doi">10.5005/jp-journals-10018-1317</idno><idno type="pmc">PMC7376594</idno><idno type="wicri:Area/Main/Corpus">001001</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001001</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh.</title><author><name sortKey="Bhuyan, Muhammad Ar" sort="Bhuyan, Muhammad Ar" uniqKey="Bhuyan M" first="Muhammad Ar" last="Bhuyan">Muhammad Ar Bhuyan</name><affiliation><nlm:affiliation>Department of Medicine, Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Al Mahtab, Mamun" sort="Al Mahtab, Mamun" uniqKey="Al Mahtab M" first="Mamun" last="Al Mahtab">Mamun Al Mahtab</name><affiliation><nlm:affiliation>Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Ashab, Eshita" sort="Ashab, Eshita" uniqKey="Ashab E" first="Eshita" last="Ashab">Eshita Ashab</name><affiliation><nlm:affiliation>Department of Cardiology, Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Haque, Md Jahirul" sort="Haque, Md Jahirul" uniqKey="Haque M" first="Md Jahirul" last="Haque">Md Jahirul Haque</name><affiliation><nlm:affiliation>Department of Medicine, Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Hoque, Syed Md M" sort="Hoque, Syed Md M" uniqKey="Hoque S" first="Syed Md M" last="Hoque">Syed Md M. Hoque</name><affiliation><nlm:affiliation>Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Faizul Huq, Akm" sort="Faizul Huq, Akm" uniqKey="Faizul Huq A" first="Akm" last="Faizul Huq">Akm Faizul Huq</name><affiliation><nlm:affiliation>Department of Medicine, Combined Military Hospital, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Islam, Md Atikul" sort="Islam, Md Atikul" uniqKey="Islam M" first="Md Atikul" last="Islam">Md Atikul Islam</name><affiliation><nlm:affiliation>Department of Medical Gastroenterology, Sheikh Russel Gastroliver Institute and Hospital, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Choudhury, Nuzhat" sort="Choudhury, Nuzhat" uniqKey="Choudhury N" first="Nuzhat" last="Choudhury">Nuzhat Choudhury</name><affiliation><nlm:affiliation>Department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Alia, Reema A" sort="Alia, Reema A" uniqKey="Alia R" first="Reema A" last="Alia">Reema A. Alia</name><affiliation><nlm:affiliation>Department of Paediatrics, Uttara Adhunik Medical College, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Mahtab, Musarrat" sort="Mahtab, Musarrat" uniqKey="Mahtab M" first="Musarrat" last="Mahtab">Musarrat Mahtab</name><affiliation><nlm:affiliation>Department of Biochemistry and Biotechnology, North South University, Dhaka, Bangladesh.</nlm:affiliation></affiliation></author><author><name sortKey="Khan, Md Sakirul I" sort="Khan, Md Sakirul I" uniqKey="Khan M" first="Md Sakirul I" last="Khan">Md Sakirul I. Khan</name><affiliation><nlm:affiliation>Department of Anatomy and Embryology, Ehime University Graduate School of Medicine, Ehime, Japan.</nlm:affiliation></affiliation></author><author><name sortKey="Akbar, Sheikh Mf" sort="Akbar, Sheikh Mf" uniqKey="Akbar S" first="Sheikh Mf" last="Akbar">Sheikh Mf Akbar</name><affiliation><nlm:affiliation>Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan; Miyakawa Memorial Research Foundation, Tokyo, Japan.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Euroasian journal of hepato-gastroenterology</title><idno type="ISSN">2231-5047</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>Background and aim</b></p><p>Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has induced a sense of panic around the world as the disease is highly contagious and has been spreading in full swing during last 5 months causing millions of COVID-19 patients and hundreds of thousands of deaths. Bangladesh, a country of 170 million people, is not an exception regarding COVID-19; it has reported several thousand COVID-19 patients with several hundred of deaths. This observational study has been planned to assess the scope and limitation of management strategy against COVID-19 patients in a medical college hospital of Bangladesh with available drugs in a real-life situation.</p></div><div type="abstract" xml:lang="en"><p><b>Materials and methods</b></p><p>All patients in this cohort (</p></div><div type="abstract" xml:lang="en"><p><b>Results</b></p><p>Out of total 33 patients, 1 patient died at day 4 day after admission. Two patients developed severe complications and were referred to tertiary hospital in Dhaka (2 and 3 days after admission), the capital of Bangladesh, where they recovered and were discharged from hospital after being SARS-CoV-2 negative. The rest 30 patients were discharged from the medical college hospital after being negative for SARS-CoV-2 in two subsequent assessments and improvement of their COVID-related symptoms. The average hospital stay of these patients was 14.5 days with a range of 10-24 days.</p></div><div type="abstract" xml:lang="en"><p><b>Conclusion</b></p><p>It seems that most of the COVID-19 patients may be adequately managed by standard of care management with drug support. However, early diagnosis and hospitalization with adequate care may be important variables for better survival. These factors may be properly ensured if the patient burden remains at a palatable level in forthcoming days in Bangladesh.</p></div><div type="abstract" xml:lang="en"><p><b>How to cite this article</b></p><p>Bhuyan MAR, Al Mahtab M, Ashab E, </p></div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32742969</PMID><DateRevised><Year>2020</Year><Month>09</Month><Day>28</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">2231-5047</ISSN><JournalIssue CitedMedium="Print"><Volume>10</Volume><Issue>1</Issue><PubDate><MedlineDate>2020 Jan-Jun</MedlineDate></PubDate></JournalIssue><Title>Euroasian journal of hepato-gastroenterology</Title><ISOAbbreviation>Euroasian J Hepatogastroenterol</ISOAbbreviation></Journal><ArticleTitle>Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh.</ArticleTitle><Pagination><MedlinePgn>27-30</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.5005/jp-journals-10018-1317</ELocationID><Abstract><AbstractText Label="Background and aim" NlmCategory="UNASSIGNED">Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has induced a sense of panic around the world as the disease is highly contagious and has been spreading in full swing during last 5 months causing millions of COVID-19 patients and hundreds of thousands of deaths. Bangladesh, a country of 170 million people, is not an exception regarding COVID-19; it has reported several thousand COVID-19 patients with several hundred of deaths. This observational study has been planned to assess the scope and limitation of management strategy against COVID-19 patients in a medical college hospital of Bangladesh with available drugs in a real-life situation.</AbstractText><AbstractText Label="Materials and methods" NlmCategory="UNASSIGNED">All patients in this cohort (<i>N</i>: 33) were positive for SARS-CoV-2 by polymerase chain reaction (PCR) and they attended the hospital with variable presenting symptoms those ranged from cough and fever to respiratory distress and pneumonia. As per the protocol, the patients were regularly evaluated for several parameters of COVID-19-related pathology. Before discharge, they were checked for SARS-CoV-2 for 2 consecutive times. The management strategy included standard of care (SoC) and administration of hydroxychloroquine and azythromycin, available in Bangladesh.</AbstractText><AbstractText Label="Results" NlmCategory="UNASSIGNED">Out of total 33 patients, 1 patient died at day 4 day after admission. Two patients developed severe complications and were referred to tertiary hospital in Dhaka (2 and 3 days after admission), the capital of Bangladesh, where they recovered and were discharged from hospital after being SARS-CoV-2 negative. The rest 30 patients were discharged from the medical college hospital after being negative for SARS-CoV-2 in two subsequent assessments and improvement of their COVID-related symptoms. The average hospital stay of these patients was 14.5 days with a range of 10-24 days.</AbstractText><AbstractText Label="Conclusion" NlmCategory="UNASSIGNED">It seems that most of the COVID-19 patients may be adequately managed by standard of care management with drug support. However, early diagnosis and hospitalization with adequate care may be important variables for better survival. These factors may be properly ensured if the patient burden remains at a palatable level in forthcoming days in Bangladesh.</AbstractText><AbstractText Label="How to cite this article" NlmCategory="UNASSIGNED">Bhuyan MAR, Al Mahtab M, Ashab E, <i>et al.</i> Treatment of COVID-19 Patients at a Medical College Hospital in Bangladesh. Euroasian J Hepato-Gastroenterol 2020;10(1):27-30.</AbstractText><CopyrightInformation>Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bhuyan</LastName><ForeName>Muhammad Ar</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Medicine, Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Al Mahtab</LastName><ForeName>Mamun</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ashab</LastName><ForeName>Eshita</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Cardiology, Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Haque</LastName><ForeName>Md Jahirul</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Department of Medicine, Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hoque</LastName><ForeName>Syed Md M</ForeName><Initials>SMM</Initials><AffiliationInfo><Affiliation>Shaheed Syed Nazrul Islam Medical College Hospital, Kishoreganj, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Faizul Huq</LastName><ForeName>Akm</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Medicine, Combined Military Hospital, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Islam</LastName><ForeName>Md Atikul</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Medical Gastroenterology, Sheikh Russel Gastroliver Institute and Hospital, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Choudhury</LastName><ForeName>Nuzhat</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Alia</LastName><ForeName>Reema A</ForeName><Initials>RA</Initials><AffiliationInfo><Affiliation>Department of Paediatrics, Uttara Adhunik Medical College, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mahtab</LastName><ForeName>Musarrat</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Biochemistry and Biotechnology, North South University, Dhaka, Bangladesh.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khan</LastName><ForeName>Md Sakirul I</ForeName><Initials>MSI</Initials><AffiliationInfo><Affiliation>Department of Anatomy and Embryology, Ehime University Graduate School of Medicine, Ehime, Japan.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Akbar</LastName><ForeName>Sheikh Mf</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan; Miyakawa Memorial Research Foundation, Tokyo, Japan.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>India</Country><MedlineTA>Euroasian J Hepatogastroenterol</MedlineTA><NlmUniqueID>101577625</NlmUniqueID><ISSNLinking>2231-5047</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Bangladesh</Keyword><Keyword MajorTopicYN="N">Coronavirus disease 2019</Keyword><Keyword MajorTopicYN="N">Therapy</Keyword></KeywordList><CoiStatement>Source of support: Nil Conflict of interest: None</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>8</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>8</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>8</Month><Day>4</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32742969</ArticleId><ArticleId IdType="doi">10.5005/jp-journals-10018-1317</ArticleId><ArticleId IdType="pmc">PMC7376594</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Infect Genet Evol. 2020 Sep;83:104351</Citation><ArticleIdList><ArticleId IdType="pubmed">32387564</ArticleId></ArticleIdList></Reference><Reference><Citation>Microb Pathog. 2020 Aug;145:104209</Citation><ArticleIdList><ArticleId IdType="pubmed">32311431</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Feb 20;382(8):727-733</Citation><ArticleIdList><ArticleId IdType="pubmed">31978945</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA Intern Med. 2020 May 1;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32356871</ArticleId></ArticleIdList></Reference><Reference><Citation>Br J Haematol. 2020 May;189(3):428-437</Citation><ArticleIdList><ArticleId IdType="pubmed">32297671</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Antimicrob Agents. 2020 Mar;55(3):105924</Citation><ArticleIdList><ArticleId IdType="pubmed">32081636</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunother Cancer. 2018 Jun 15;6(1):56</Citation><ArticleIdList><ArticleId IdType="pubmed">29907163</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Mar 5;382(10):929-936</Citation><ArticleIdList><ArticleId IdType="pubmed">32004427</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Mar 19;382(12):1177-1179</Citation><ArticleIdList><ArticleId IdType="pubmed">32074444</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Mar 5;382(10):970-971</Citation><ArticleIdList><ArticleId IdType="pubmed">32003551</ArticleId></ArticleIdList></Reference><Reference><Citation>Travel Med Infect Dis. 2020 May - Jun;35:101738</Citation><ArticleIdList><ArticleId IdType="pubmed">32387409</ArticleId></ArticleIdList></Reference><Reference><Citation>Semin Immunopathol. 2017 Jul;39(5):517-528</Citation><ArticleIdList><ArticleId IdType="pubmed">28555385</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect. 2020 Jun;80(6):607-613</Citation><ArticleIdList><ArticleId IdType="pubmed">32283152</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Microbiol. 2020 Apr;5(4):536-544</Citation><ArticleIdList><ArticleId IdType="pubmed">32123347</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Clin Microbiol Infect Dis. 2020 Jun;39(6):1059-1061</Citation><ArticleIdList><ArticleId IdType="pubmed">32342252</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Mar 26;382(13):1278-1280</Citation><ArticleIdList><ArticleId IdType="pubmed">32069388</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2020 Feb 21;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32083643</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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