[Differential diagnosis of hydroxychloroquine-induced retinal damage].
Identifieur interne : 000D05 ( Main/Corpus ); précédent : 000D04; suivant : 000D06[Differential diagnosis of hydroxychloroquine-induced retinal damage].
Auteurs : M V Budzinskaya ; M H DurzhinskayaSource :
- Vestnik oftalmologii [ 0042-465X ] ; 2020.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antiviral Agents, Hydroxychloroquine.
- diagnosis : Pneumonia, Viral.
- drug therapy : Pneumonia, Viral.
- Betacoronavirus, Diagnosis, Differential, Humans, Pandemics.
Abstract
Coronavirus infection is currently en extremely relevant scientific topic due to the emergence of a new serotype that causes a condition identified as Severe Acute Respiratory Syndrome (SARS)-COV-2. Chloroquine and hydroxychloroquine have a long history of use against other infectious diseases, they are available and inexpensive, so the possibility of using them in vivo and in vitro to suppress the infectious agent was examined. Despite the noted therapeutic potential of these drugs, it was necessary to take into account the toxicological aspects that dictate the importance of rational use of 4-aminoquinoline derivatives. This review analyzes literature on the development patterns of hydroxychloroquine retinopathy, basic principles of diagnosis and differentiation of this condition from other types of retinal pathology.
DOI: 10.17116/oftalma2020136042265
PubMed: 32880149
Links to Exploration step
pubmed:32880149Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Differential diagnosis of hydroxychloroquine-induced retinal damage].</title>
<author><name sortKey="Budzinskaya, M V" sort="Budzinskaya, M V" uniqKey="Budzinskaya M" first="M V" last="Budzinskaya">M V Budzinskaya</name>
<affiliation><nlm:affiliation>Research Institute of Eye Diseases, Moscow, Russia.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Durzhinskaya, M H" sort="Durzhinskaya, M H" uniqKey="Durzhinskaya M" first="M H" last="Durzhinskaya">M H Durzhinskaya</name>
<affiliation><nlm:affiliation>Research Institute of Eye Diseases, Moscow, Russia.</nlm:affiliation>
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<author><name sortKey="Budzinskaya, M V" sort="Budzinskaya, M V" uniqKey="Budzinskaya M" first="M V" last="Budzinskaya">M V Budzinskaya</name>
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<author><name sortKey="Durzhinskaya, M H" sort="Durzhinskaya, M H" uniqKey="Durzhinskaya M" first="M H" last="Durzhinskaya">M H Durzhinskaya</name>
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<imprint><date when="2020" type="published">2020</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiviral Agents (therapeutic use)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Diagnosis, Differential (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Hydroxychloroquine (therapeutic use)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (diagnosis)</term>
<term>Pneumonia, Viral (drug therapy)</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term>
<term>Hydroxychloroquine</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Betacoronavirus</term>
<term>Diagnosis, Differential</term>
<term>Humans</term>
<term>Pandemics</term>
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<front><div type="abstract" xml:lang="en">Coronavirus infection is currently en extremely relevant scientific topic due to the emergence of a new serotype that causes a condition identified as Severe Acute Respiratory Syndrome (SARS)-COV-2. Chloroquine and hydroxychloroquine have a long history of use against other infectious diseases, they are available and inexpensive, so the possibility of using them <i>in vivo</i>
and <i>in vitro</i>
to suppress the infectious agent was examined. Despite the noted therapeutic potential of these drugs, it was necessary to take into account the toxicological aspects that dictate the importance of rational use of 4-aminoquinoline derivatives. This review analyzes literature on the development patterns of hydroxychloroquine retinopathy, basic principles of diagnosis and differentiation of this condition from other types of retinal pathology.</div>
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<DateCompleted><Year>2020</Year>
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<Month>09</Month>
<Day>04</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Print">0042-465X</ISSN>
<JournalIssue CitedMedium="Print"><Volume>136</Volume>
<Issue>4. Vyp. 2</Issue>
<PubDate><Year>2020</Year>
</PubDate>
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<Title>Vestnik oftalmologii</Title>
<ISOAbbreviation>Vestn Oftalmol</ISOAbbreviation>
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<ArticleTitle>[Differential diagnosis of hydroxychloroquine-induced retinal damage].</ArticleTitle>
<Pagination><MedlinePgn>265-271</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.17116/oftalma2020136042265</ELocationID>
<Abstract><AbstractText>Coronavirus infection is currently en extremely relevant scientific topic due to the emergence of a new serotype that causes a condition identified as Severe Acute Respiratory Syndrome (SARS)-COV-2. Chloroquine and hydroxychloroquine have a long history of use against other infectious diseases, they are available and inexpensive, so the possibility of using them <i>in vivo</i>
and <i>in vitro</i>
to suppress the infectious agent was examined. Despite the noted therapeutic potential of these drugs, it was necessary to take into account the toxicological aspects that dictate the importance of rational use of 4-aminoquinoline derivatives. This review analyzes literature on the development patterns of hydroxychloroquine retinopathy, basic principles of diagnosis and differentiation of this condition from other types of retinal pathology.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Budzinskaya</LastName>
<ForeName>M V</ForeName>
<Initials>MV</Initials>
<Identifier Source="ORCID">0000-0002-5507-8775</Identifier>
<AffiliationInfo><Affiliation>Research Institute of Eye Diseases, Moscow, Russia.</Affiliation>
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<Author ValidYN="Y"><LastName>Durzhinskaya</LastName>
<ForeName>M H</ForeName>
<Initials>MH</Initials>
<Identifier Source="ORCID">0000-0002-3806-3985</Identifier>
<AffiliationInfo><Affiliation>Research Institute of Eye Diseases, Moscow, Russia.</Affiliation>
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<VernacularTitle>Differentsial'naya diagnostika porazheniya setchatki pri toksicheskom vozdeistvii gidroksikhlorokhina.</VernacularTitle>
</Article>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
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<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="Y">Betacoronavirus</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
</MeshHeadingList>
<OtherAbstract Type="Publisher" Language="rus"><AbstractText>Коронавирусная инфекция в настоящее время является крайне актуальной темой в научном мире по причине появления нового серотипа, вызывающего состояние, идентифицируемое как тяжелый острый респираторный синдром (SARS)-COV-2. В связи с длительной историей применения при других инфекционных заболеваниях, доступностью и относительно низкой стоимостью рассмотрена возможность применения хлорохина и гидроксихлорохина <i>in vivo</i>
и <i>in vitro</i>
исследована способность этих препаратов подавлять возбудитель SARS-CoV-2. Несмотря на то, что исследователи отметили терапевтический потенциал этих препаратов, необходимо учитывать токсикологические аспекты, диктующие важность рационального употребления 4-аминохинолиновых производных. Данный обзор литературы посвящен анализу закономерности развития токсической ретинопатии на фоне приема гидроксихлорохина, основным принципам диагностики и дифференциальной диагностики данного состояния и других видов патологии сетчатки.</AbstractText>
</OtherAbstract>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">coronavirus</Keyword>
<Keyword MajorTopicYN="N">hydroxychloroquine</Keyword>
<Keyword MajorTopicYN="N">toxic retinopathy</Keyword>
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