Hydroxychloroquine in a G6PD-Deficient Patient with COVID-19 Complicated by Haemolytic Anaemia: Culprit or Innocent Bystander?
Identifieur interne : 000C50 ( Main/Corpus ); précédent : 000C49; suivant : 000C51Hydroxychloroquine in a G6PD-Deficient Patient with COVID-19 Complicated by Haemolytic Anaemia: Culprit or Innocent Bystander?
Auteurs : François Mastroianni ; Vincent Colombie ; Geraldine Claes ; Axelle Gilles ; Frédéric Vandergheynst ; Sammy PlaceSource :
- European journal of case reports in internal medicine [ 2284-2594 ] ; 2020.
Abstract
Hydroxychloroquine has been used worldwide as a first-line treatment for patients hospitalized with COVID-19. Little is known about COVID-19 and its effects on patients with congenital red blood cell disorders. We report a case of haemolytic anaemia in a 32-year-old patient and a fortuitous highlighting of G6PD deficiency. We reviewed the literature to assess the risk of hydroxychloroquine use in this context.
LEARNING POINTS
A rapid drop in haemoglobin in COVID-19 patients should alert physicians to test for haemolytic anaemia and enzymopathies.Our review of the literature shows that use of hydroxychloroquine is safe in G6PD-deficient patients.
DOI: 10.12890/2020_001875
PubMed: 32908842
PubMed Central: PMC7473690
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<front><div type="abstract" xml:lang="en">Hydroxychloroquine has been used worldwide as a first-line treatment for patients hospitalized with COVID-19. Little is known about COVID-19 and its effects on patients with congenital red blood cell disorders. We report a case of haemolytic anaemia in a 32-year-old patient and a fortuitous highlighting of G6PD deficiency. We reviewed the literature to assess the risk of hydroxychloroquine use in this context.</div>
<div type="abstract" xml:lang="en"><p><b>LEARNING POINTS</b>
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<p>A rapid drop in haemoglobin in COVID-19 patients should alert physicians to test for haemolytic anaemia and enzymopathies.Our review of the literature shows that use of hydroxychloroquine is safe in G6PD-deficient patients.</p>
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<Abstract><AbstractText>Hydroxychloroquine has been used worldwide as a first-line treatment for patients hospitalized with COVID-19. Little is known about COVID-19 and its effects on patients with congenital red blood cell disorders. We report a case of haemolytic anaemia in a 32-year-old patient and a fortuitous highlighting of G6PD deficiency. We reviewed the literature to assess the risk of hydroxychloroquine use in this context.</AbstractText>
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<ReferenceList><Reference><Citation>Infect Dis (Lond). 2020 Sep;52(9):659-661</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32496938</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>JAMA. 2020 Mar 17;323(11):1061-1069</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32031570</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2020 Jul 28;71(15):732-739</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32150618</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Drug Saf. 2010 Sep 1;33(9):713-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20701405</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur J Haematol. 2020 Sep;105(3):357-359</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32324284</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2008 Jan 5;371(9606):64-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18177777</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2008 Sep;89(Pt 9):2080-2089</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18753216</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arthritis Care Res (Hoboken). 2018 Mar;70(3):481-485</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28556555</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Antimicrob Agents. 2020 Jul;56(1):105949</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32205204</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur J Haematol. 2020 Jun 5;:</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32500556</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2008 Mar 15;197(6):812-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18269318</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
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