CovidChloroV1, Main, Corpus, bibRecord, 000B22

COVID-19: Antiviral Agents, Antibody Development and Traditional Chinese Medicine.

Identifieur interne : 000B22 ( Main/Corpus ); précédent : 000B21; suivant : 000B23

COVID-19: Antiviral Agents, Antibody Development and Traditional Chinese Medicine.

Auteurs : Wenyi Guan ; Wendong Lan ; Jing Zhang ; Shan Zhao ; Junxian Ou ; Xiaowei Wu ; Yuqian Yan ; Jianguo Wu ; Qiwei Zhang

Source :

Virologica Sinica [ 1995-820X ] ; 2020.

RBID : pubmed:32997322

English descriptors

KwdEn :
- Adenosine Monophosphate (analogs & derivatives), Adenosine Monophosphate (therapeutic use), Alanine (analogs & derivatives), Alanine (therapeutic use), Amides (therapeutic use), Animals (MeSH), Antibodies, Viral (administration & dosage), Antibodies, Viral (immunology), Antiviral Agents (pharmacology), Antiviral Agents (therapeutic use), COVID-19 (drug therapy), COVID-19 (immunology), COVID-19 (therapy), Drug Repositioning (MeSH), Humans (MeSH), Immunization, Passive (MeSH), Medicine, Chinese Traditional (methods), Pandemics (MeSH), Pyrazines (therapeutic use), SARS-CoV-2 (drug effects), World Health Organization (MeSH).
MESH :
- chemical , administration & dosage : Antibodies, Viral.
- chemical , analogs & derivatives : Adenosine Monophosphate, Alanine.
- chemical , immunology : Antibodies, Viral.
- chemical , pharmacology : Antiviral Agents.
- chemical , therapeutic use : Adenosine Monophosphate, Alanine, Amides, Antiviral Agents, Pyrazines.
- drug effects : SARS-CoV-2.
- drug therapy : COVID-19.
- immunology : COVID-19.
- methods : Medicine, Chinese Traditional.
- therapy : COVID-19.
- Animals, Drug Repositioning, Humans, Immunization, Passive, Pandemics, World Health Organization.

Abstract

The World Health Organization (WHO) has declared coronavirus disease 2019 (COVID-19) is the first pandemic caused by coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there is no effective anti-SARS-CoV-2 drug approved worldwide for treatment of patients with COVID-19. Therapeutic options in response to the COVID-19 outbreak are urgently needed. To facilitate the better and faster development of therapeutic COVID-19 drugs, we present an overview of the global promising therapeutic drugs, including repurposing existing antiviral agents, network-based pharmacology research, antibody development and traditional Chinese medicine. Among all these drugs, we focus on the most promising drugs (such as favipiravir, tocilizumab, SARS-CoV-2 convalescent plasma, hydroxychloroquine, Lianhua Qingwen, interferon beta-1a, remdesivir, etc.) that have or will enter the final stage of human testing-phase III-IV clinical trials.

DOI: 10.1007/s12250-020-00297-0
PubMed: 32997322
PubMed Central: PMC7524871

Links to Exploration step

pubmed:32997322

Le document en format XML

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<term>Immunization, Passive (MeSH)</term>
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<term>Pandemics (MeSH)</term>
<term>Pyrazines (therapeutic use)</term>
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<front><div type="abstract" xml:lang="en">The World Health Organization (WHO) has declared coronavirus disease 2019 (COVID-19) is the first pandemic caused by coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there is no effective anti-SARS-CoV-2 drug approved worldwide for treatment of patients with COVID-19. Therapeutic options in response to the COVID-19 outbreak are urgently needed. To facilitate the better and faster development of therapeutic COVID-19 drugs, we present an overview of the global promising therapeutic drugs, including repurposing existing antiviral agents, network-based pharmacology research, antibody development and traditional Chinese medicine. Among all these drugs, we focus on the most promising drugs (such as favipiravir, tocilizumab, SARS-CoV-2 convalescent plasma, hydroxychloroquine, Lianhua Qingwen, interferon beta-1a, remdesivir, etc.) that have or will enter the final stage of human testing-phase III-IV clinical trials.</div>
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<Abstract><AbstractText>The World Health Organization (WHO) has declared coronavirus disease 2019 (COVID-19) is the first pandemic caused by coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, there is no effective anti-SARS-CoV-2 drug approved worldwide for treatment of patients with COVID-19. Therapeutic options in response to the COVID-19 outbreak are urgently needed. To facilitate the better and faster development of therapeutic COVID-19 drugs, we present an overview of the global promising therapeutic drugs, including repurposing existing antiviral agents, network-based pharmacology research, antibody development and traditional Chinese medicine. Among all these drugs, we focus on the most promising drugs (such as favipiravir, tocilizumab, SARS-CoV-2 convalescent plasma, hydroxychloroquine, Lianhua Qingwen, interferon beta-1a, remdesivir, etc.) that have or will enter the final stage of human testing-phase III-IV clinical trials.</AbstractText>
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<ReferenceList><Reference><Citation>Nature. 2014 Oct 2;514(7520):47-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25171469</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Drug Discov. 2016 May;15(5):327-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26868298</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pharmacol Res. 2020 May;155:104743</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32145402</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Antimicrob Agents. 2007 Oct;30(4):297-308</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17629679</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Drug Discov. 2020 Mar;19(3):149-150</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32127666</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol Sin. 2020 Jun;35(3):253-255</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32048130</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antimicrob Agents Chemother. 2004 Mar;48(3):747-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14982759</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vopr Virusol. 2008 Jul-Aug;53(4):9-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18756809</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pharmacol Res. 2020 Jul;157:104820</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32360484</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antimicrob Agents Chemother. 2014 Aug;58(8):4885-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24841273</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Microbes Infect. 2020 Dec;9(1):382-385</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32065055</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2020 Mar;579(7798):270-273</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32015507</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2020 Aug;584(7819):120-124</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32454512</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Plants. 2020 Mar;6(3):177</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32170291</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 May 30;395(10238):1695-1704</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32401715</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2011 Feb 15;52(4):447-56</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21248066</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antimicrob Agents Chemother. 1990 Aug;34(8):1512-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2221859</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Eur J Clin Microbiol Infect Dis. 2005 Jan;24(1):44-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15616839</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Microbes Infect. 2020 Dec;9(1):221-236</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31987001</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Genet Genomics. 2020 Feb 20;47(2):115-117</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32171450</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol Sin. 2020 Jun;35(3):266-271</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32125642</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Complement Altern Med. 2017 Feb 24;17(1):130</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28235408</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biomed J. 2020 Aug;43(4):355-362</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32426387</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2020 Feb 20;382(8):727-733</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31978945</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Res. 2020 Mar;30(3):269-271</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32020029</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Commun. 2020 May 4;11(1):2251</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32366817</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Pharmacol Ther. 2020 Aug;108(2):242-247</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32246834</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Future Microbiol. 2020 May;15:557-566</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32476494</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pharmacol Res. 2020 Jun;156:104761</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32205232</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2015 Jun 25;522(7557):487-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25855300</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2020 Aug 6;383(6):517-525</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32492293</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 May 16;395(10236):1569-1578</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32423584</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2014 Feb 22;383(9918):723-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23953767</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Intern Emerg Med. 2020 Nov;15(8):1577-1578</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32347443</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2020 Dec 10;183(6):1735</Citation>
<ArticleIdList><ArticleId IdType="pubmed">33306958</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2020 Mar 5;382(10):929-936</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32004427</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Viruses. 2019 Apr 04;11(4):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30987343</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>mBio. 2018 Mar 6;9(2):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29511076</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Discov. 2020 Mar 16;6:14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32194980</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2016 Apr 22;291(17):9218-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26953343</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Mol Med. 2019;19(4):303-314</Citation>
<ArticleIdList><ArticleId IdType="pubmed">30950348</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Intern Med. 1999 Jan 25;159(2):167-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9927100</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Feline Med Surg. 2004 Apr;6(2):131-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15123159</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2005 Aug 22;2:69</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16115318</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2016 Mar 17;531(7594):381-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26934220</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Commun. 2020 Jan 10;11(1):222</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31924756</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biomol Struct Dyn. 2021 May;39(8):2679-2692</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32266873</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2020 May 19;117(20):10970-10975</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32350134</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Microbiol. 2020 Apr;5(4):536-544</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32123347</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 Feb 15;395(10223):497-506</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31986264</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMJ. 2020 Jun 16;369:m2422</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32546467</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Funct Foods. 2020 Aug;71:104016</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32421102</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol Sin. 2020 Jun;35(3):321-329</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32500504</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>JAMA Intern Med. 2020 Jul 1;180(7):934-943</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32167524</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2007 Oct 4;357(14):1450-1</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17914053</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Med Chem. 2008;15(10):997-1005</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18393857</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2020 Jun 13;395(10240):1820</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32511943</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Biotechnol. 2020 Apr;38(4):379-381</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32205870</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2003 Nov;3(11):722-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14592603</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Virol. 2019 Apr;35:57-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">31125806</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 2020 Apr 16;181(2):271-280.e8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32142651</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Chem. 2005 Feb 24;48(4):1256-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15715493</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Antimicrob Agents. 2020 Apr;55(4):105933</Citation>
<ArticleIdList><ArticleId IdType="pubmed">32147516</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2006 Feb;6(2):67-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16439323</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

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