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Effect of pre-existing diseases on COVID-19 infection and role of new sensors and biomaterials for its detection and treatment.

Identifieur interne : 000854 ( Main/Corpus ); précédent : 000853; suivant : 000855

Effect of pre-existing diseases on COVID-19 infection and role of new sensors and biomaterials for its detection and treatment.

Auteurs : Angaraj Singh ; Manoj Kumar ; Ashutosh Kumar Dubey

Source :

RBID : pubmed:33173852

Abstract

The entire world is suffering from a new type of viral disease, occurred by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The present article briefly discussed the genome sequencing and interaction of host cells with SARS-CoV-2. The influence of pre-existing diseases such as diabetes, heart disease and age of the patients on COVID-19 infection is reviewed. The possible treatments of SARS-CoV-2 including antiviral drugs, Chinese traditional treatment and plasma therapy are elaborately discussed. The proper vaccine for COVID-19 is not available till date. However, the trials of pre-existing antiviral vaccines such as, chloroquine/hydroxychloroquine, remdesivir, ritonavir and lopinavir and their consequences are briefly presented. Further, the importance of new materials and devices for the detection and treatment of COVID-19 has also been reviewed. The polymerase chain reaction (PCR)-based, and non-PCR based devices are used for the detection of COVID-19 infection. The non-PCR based devices provide rapid results as compared to PCR based devices.

DOI: 10.1002/mds3.10140
PubMed: 33173852
PubMed Central: PMC7645882

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pubmed:33173852

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