Clinical Characteristics and Outcomes of 905 COVID-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran.
Identifieur interne : 000792 ( Main/Corpus ); précédent : 000791; suivant : 000793Clinical Characteristics and Outcomes of 905 COVID-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran.
Auteurs : Seyed Farshad Allameh ; Saeed Nemati ; Reza Ghalehtaki ; Esmaeil Mohammadnejad ; Seyed Mojtaba Aghili ; Nasim Khajavirad ; Mohammad-Taghi Beigmohammadi ; Mohammadreza Salehi ; Hadi Mirfazaelian ; Maryam Edalatifard ; Hossein Kazemizadeh ; Seyed Ali Dehghan Manshadi ; Maliheh Hasannezhad ; Laya Amoozadeh ; Masoud Radnia ; Seyedeh Rana Khatami ; Azin Nahvijou ; Monireh Sadat Seyyedsalehi ; Laleh Rashidian ; Niloofar Ayoobi Yazdi ; Mohsen Nasiri Toosi ; Khosro Sadeghniiat-Haghighi ; Ali Jafarian ; Masud Yunesian ; Kazem ZendehdelSource :
- Archives of Iranian medicine [ 1735-3947 ] ; 2020.
English descriptors
- KwdEn :
- Adult (MeSH), Aged (MeSH), COVID-19 (diagnosis), COVID-19 (drug therapy), COVID-19 (mortality), COVID-19 (physiopathology), COVID-19 Nucleic Acid Testing (standards), COVID-19 Nucleic Acid Testing (statistics & numerical data), Comorbidity (MeSH), Female (MeSH), Humans (MeSH), Hydroxychloroquine (therapeutic use), Intensive Care Units (statistics & numerical data), Iran (epidemiology), Length of Stay (statistics & numerical data), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Respiration, Artificial (adverse effects), Retrospective Studies (MeSH), SARS-CoV-2 (MeSH), Severity of Illness Index (MeSH).
- MESH :
- chemical , therapeutic use : Hydroxychloroquine.
- geographic , epidemiology : Iran.
- adverse effects : Respiration, Artificial.
- diagnosis : COVID-19.
- drug therapy : COVID-19.
- mortality : COVID-19.
- physiopathology : COVID-19.
- standards : COVID-19 Nucleic Acid Testing.
- statistics & numerical data : COVID-19 Nucleic Acid Testing, Intensive Care Units, Length of Stay.
- Adult, Aged, Comorbidity, Female, Humans, Male, Middle Aged, Pandemics, Retrospective Studies, SARS-CoV-2, Severity of Illness Index.
Abstract
BACKGROUND
We studied the clinical characteristics and outcomes of 905 hospitalized coronavirus disease 2019 (COVID-19) patients admitted to Imam Khomeini Hospital Complex (IKHC), Tehran, Iran.
METHODS
COVID-19 patients were recruited based on clinical symptoms and patterns of computed tomography (CT) imaging between February 20 and March 19. All patients were tested for the presence of COVID-19 RNA. The Poisson regression model estimated the incidence rate ratio (IRR) for different parameters.
RESULTS
The average age (± standard deviation) was 56.9 (±15.7) years and 61.77% were male. The most common symptoms were fever (93.59%), dry cough (79.78%), and dyspnea (75.69%). Only 43.76% of patients were positive for the RT-PCR COVID-19 test. Prevalence of lymphopenia was 42.9% and more than 90% had elevated lactate dehydrogenase (LDH) or C-reactive protein (CRP). About 11% were severe cases, and 13.7% died in the hospital. The median length of stay (LOS) was 3 days. We found higher risks of mortality in patients who were older than 70 years (IRR = 11.77, 95% CI 3.63-38.18), underwent mechanical ventilation (IRR = 7.36, 95% CI 5.06-10.7), were admitted to the intensive care unit (ICU) (IRR = 5.47, 95% CI 4.00-8.38), tested positive on the COVID-19 test (IRR = 2.80, 95% CI 1.64-3.55), and reported a history of comorbidity (IRR = 1.76, 95% CI 1.07-2.89) compared to their corresponding reference groups. Hydroxychloroquine therapy was not associated with mortality in our study.
CONCLUSION
Older age, experiencing a severe form of the disease, and having a comorbidity were the most important prognostic factors for COVID-19 infection. Larger studies are needed to perform further subgroup analyses and verify high-risk groups.
DOI: 10.34172/aim.2020.102
PubMed: 33220695
Links to Exploration step
pubmed:33220695Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinical Characteristics and Outcomes of 905 COVID-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran.</title><author><name sortKey="Allameh, Seyed Farshad" sort="Allameh, Seyed Farshad" uniqKey="Allameh S" first="Seyed Farshad" last="Allameh">Seyed Farshad Allameh</name><affiliation><nlm:affiliation>Gastroenterology Ward, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nemati, Saeed" sort="Nemati, Saeed" uniqKey="Nemati S" first="Saeed" last="Nemati">Saeed Nemati</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ghalehtaki, Reza" sort="Ghalehtaki, Reza" uniqKey="Ghalehtaki R" first="Reza" last="Ghalehtaki">Reza Ghalehtaki</name><affiliation><nlm:affiliation>Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Mohammadnejad, Esmaeil" sort="Mohammadnejad, Esmaeil" uniqKey="Mohammadnejad E" first="Esmaeil" last="Mohammadnejad">Esmaeil Mohammadnejad</name><affiliation><nlm:affiliation>Department of Medical-Surgical Nursing and Basic Sciences, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Aghili, Seyed Mojtaba" sort="Aghili, Seyed Mojtaba" uniqKey="Aghili S" first="Seyed Mojtaba" last="Aghili">Seyed Mojtaba Aghili</name><affiliation><nlm:affiliation>Department of Emergency Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Khajavirad, Nasim" sort="Khajavirad, Nasim" uniqKey="Khajavirad N" first="Nasim" last="Khajavirad">Nasim Khajavirad</name><affiliation><nlm:affiliation>Department of Internal Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Beigmohammadi, Mohammad Taghi" sort="Beigmohammadi, Mohammad Taghi" uniqKey="Beigmohammadi M" first="Mohammad-Taghi" last="Beigmohammadi">Mohammad-Taghi Beigmohammadi</name><affiliation><nlm:affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Salehi, Mohammadreza" sort="Salehi, Mohammadreza" uniqKey="Salehi M" first="Mohammadreza" last="Salehi">Mohammadreza Salehi</name><affiliation><nlm:affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Mirfazaelian, Hadi" sort="Mirfazaelian, Hadi" uniqKey="Mirfazaelian H" first="Hadi" last="Mirfazaelian">Hadi Mirfazaelian</name><affiliation><nlm:affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Edalatifard, Maryam" sort="Edalatifard, Maryam" uniqKey="Edalatifard M" first="Maryam" last="Edalatifard">Maryam Edalatifard</name><affiliation><nlm:affiliation>Department of Pulmonology, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Kazemizadeh, Hossein" sort="Kazemizadeh, Hossein" uniqKey="Kazemizadeh H" first="Hossein" last="Kazemizadeh">Hossein Kazemizadeh</name><affiliation><nlm:affiliation>Department of Pulmonology, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Dehghan Manshadi, Seyed Ali" sort="Dehghan Manshadi, Seyed Ali" uniqKey="Dehghan Manshadi S" first="Seyed Ali" last="Dehghan Manshadi">Seyed Ali Dehghan Manshadi</name><affiliation><nlm:affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Hasannezhad, Maliheh" sort="Hasannezhad, Maliheh" uniqKey="Hasannezhad M" first="Maliheh" last="Hasannezhad">Maliheh Hasannezhad</name><affiliation><nlm:affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Amoozadeh, Laya" sort="Amoozadeh, Laya" uniqKey="Amoozadeh L" first="Laya" last="Amoozadeh">Laya Amoozadeh</name><affiliation><nlm:affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Radnia, Masoud" sort="Radnia, Masoud" uniqKey="Radnia M" first="Masoud" last="Radnia">Masoud Radnia</name><affiliation><nlm:affiliation>Department of Internal Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Khatami, Seyedeh Rana" sort="Khatami, Seyedeh Rana" uniqKey="Khatami S" first="Seyedeh Rana" last="Khatami">Seyedeh Rana Khatami</name><affiliation><nlm:affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nahvijou, Azin" sort="Nahvijou, Azin" uniqKey="Nahvijou A" first="Azin" last="Nahvijou">Azin Nahvijou</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Seyyedsalehi, Monireh Sadat" sort="Seyyedsalehi, Monireh Sadat" uniqKey="Seyyedsalehi M" first="Monireh Sadat" last="Seyyedsalehi">Monireh Sadat Seyyedsalehi</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Rashidian, Laleh" sort="Rashidian, Laleh" uniqKey="Rashidian L" first="Laleh" last="Rashidian">Laleh Rashidian</name><affiliation><nlm:affiliation>Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ayoobi Yazdi, Niloofar" sort="Ayoobi Yazdi, Niloofar" uniqKey="Ayoobi Yazdi N" first="Niloofar" last="Ayoobi Yazdi">Niloofar Ayoobi Yazdi</name><affiliation><nlm:affiliation>Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nasiri Toosi, Mohsen" sort="Nasiri Toosi, Mohsen" uniqKey="Nasiri Toosi M" first="Mohsen" last="Nasiri Toosi">Mohsen Nasiri Toosi</name><affiliation><nlm:affiliation>Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Sadeghniiat Haghighi, Khosro" sort="Sadeghniiat Haghighi, Khosro" uniqKey="Sadeghniiat Haghighi K" first="Khosro" last="Sadeghniiat-Haghighi">Khosro Sadeghniiat-Haghighi</name><affiliation><nlm:affiliation>Occupational Sleep Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Jafarian, Ali" sort="Jafarian, Ali" uniqKey="Jafarian A" first="Ali" last="Jafarian">Ali Jafarian</name><affiliation><nlm:affiliation>Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Hepatobiliary Surgery and Liver Transplantation Division, Department of General Surgery, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Yunesian, Masud" sort="Yunesian, Masud" uniqKey="Yunesian M" first="Masud" last="Yunesian">Masud Yunesian</name><affiliation><nlm:affiliation>Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Center for Air Pollution Research (CAPR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran.</nlm:affiliation></affiliation></author><author><name sortKey="Zendehdel, Kazem" sort="Zendehdel, Kazem" uniqKey="Zendehdel K" first="Kazem" last="Zendehdel">Kazem Zendehdel</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Breast Diseases Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:33220695</idno><idno type="pmid">33220695</idno><idno type="doi">10.34172/aim.2020.102</idno><idno type="wicri:Area/Main/Corpus">000792</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000792</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical Characteristics and Outcomes of 905 COVID-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran.</title><author><name sortKey="Allameh, Seyed Farshad" sort="Allameh, Seyed Farshad" uniqKey="Allameh S" first="Seyed Farshad" last="Allameh">Seyed Farshad Allameh</name><affiliation><nlm:affiliation>Gastroenterology Ward, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nemati, Saeed" sort="Nemati, Saeed" uniqKey="Nemati S" first="Saeed" last="Nemati">Saeed Nemati</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ghalehtaki, Reza" sort="Ghalehtaki, Reza" uniqKey="Ghalehtaki R" first="Reza" last="Ghalehtaki">Reza Ghalehtaki</name><affiliation><nlm:affiliation>Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Mohammadnejad, Esmaeil" sort="Mohammadnejad, Esmaeil" uniqKey="Mohammadnejad E" first="Esmaeil" last="Mohammadnejad">Esmaeil Mohammadnejad</name><affiliation><nlm:affiliation>Department of Medical-Surgical Nursing and Basic Sciences, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Aghili, Seyed Mojtaba" sort="Aghili, Seyed Mojtaba" uniqKey="Aghili S" first="Seyed Mojtaba" last="Aghili">Seyed Mojtaba Aghili</name><affiliation><nlm:affiliation>Department of Emergency Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Khajavirad, Nasim" sort="Khajavirad, Nasim" uniqKey="Khajavirad N" first="Nasim" last="Khajavirad">Nasim Khajavirad</name><affiliation><nlm:affiliation>Department of Internal Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Beigmohammadi, Mohammad Taghi" sort="Beigmohammadi, Mohammad Taghi" uniqKey="Beigmohammadi M" first="Mohammad-Taghi" last="Beigmohammadi">Mohammad-Taghi Beigmohammadi</name><affiliation><nlm:affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Salehi, Mohammadreza" sort="Salehi, Mohammadreza" uniqKey="Salehi M" first="Mohammadreza" last="Salehi">Mohammadreza Salehi</name><affiliation><nlm:affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Mirfazaelian, Hadi" sort="Mirfazaelian, Hadi" uniqKey="Mirfazaelian H" first="Hadi" last="Mirfazaelian">Hadi Mirfazaelian</name><affiliation><nlm:affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Edalatifard, Maryam" sort="Edalatifard, Maryam" uniqKey="Edalatifard M" first="Maryam" last="Edalatifard">Maryam Edalatifard</name><affiliation><nlm:affiliation>Department of Pulmonology, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Kazemizadeh, Hossein" sort="Kazemizadeh, Hossein" uniqKey="Kazemizadeh H" first="Hossein" last="Kazemizadeh">Hossein Kazemizadeh</name><affiliation><nlm:affiliation>Department of Pulmonology, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Dehghan Manshadi, Seyed Ali" sort="Dehghan Manshadi, Seyed Ali" uniqKey="Dehghan Manshadi S" first="Seyed Ali" last="Dehghan Manshadi">Seyed Ali Dehghan Manshadi</name><affiliation><nlm:affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Hasannezhad, Maliheh" sort="Hasannezhad, Maliheh" uniqKey="Hasannezhad M" first="Maliheh" last="Hasannezhad">Maliheh Hasannezhad</name><affiliation><nlm:affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Amoozadeh, Laya" sort="Amoozadeh, Laya" uniqKey="Amoozadeh L" first="Laya" last="Amoozadeh">Laya Amoozadeh</name><affiliation><nlm:affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Radnia, Masoud" sort="Radnia, Masoud" uniqKey="Radnia M" first="Masoud" last="Radnia">Masoud Radnia</name><affiliation><nlm:affiliation>Department of Internal Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Khatami, Seyedeh Rana" sort="Khatami, Seyedeh Rana" uniqKey="Khatami S" first="Seyedeh Rana" last="Khatami">Seyedeh Rana Khatami</name><affiliation><nlm:affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nahvijou, Azin" sort="Nahvijou, Azin" uniqKey="Nahvijou A" first="Azin" last="Nahvijou">Azin Nahvijou</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Seyyedsalehi, Monireh Sadat" sort="Seyyedsalehi, Monireh Sadat" uniqKey="Seyyedsalehi M" first="Monireh Sadat" last="Seyyedsalehi">Monireh Sadat Seyyedsalehi</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Rashidian, Laleh" sort="Rashidian, Laleh" uniqKey="Rashidian L" first="Laleh" last="Rashidian">Laleh Rashidian</name><affiliation><nlm:affiliation>Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Ayoobi Yazdi, Niloofar" sort="Ayoobi Yazdi, Niloofar" uniqKey="Ayoobi Yazdi N" first="Niloofar" last="Ayoobi Yazdi">Niloofar Ayoobi Yazdi</name><affiliation><nlm:affiliation>Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Nasiri Toosi, Mohsen" sort="Nasiri Toosi, Mohsen" uniqKey="Nasiri Toosi M" first="Mohsen" last="Nasiri Toosi">Mohsen Nasiri Toosi</name><affiliation><nlm:affiliation>Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Sadeghniiat Haghighi, Khosro" sort="Sadeghniiat Haghighi, Khosro" uniqKey="Sadeghniiat Haghighi K" first="Khosro" last="Sadeghniiat-Haghighi">Khosro Sadeghniiat-Haghighi</name><affiliation><nlm:affiliation>Occupational Sleep Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Jafarian, Ali" sort="Jafarian, Ali" uniqKey="Jafarian A" first="Ali" last="Jafarian">Ali Jafarian</name><affiliation><nlm:affiliation>Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Hepatobiliary Surgery and Liver Transplantation Division, Department of General Surgery, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author><author><name sortKey="Yunesian, Masud" sort="Yunesian, Masud" uniqKey="Yunesian M" first="Masud" last="Yunesian">Masud Yunesian</name><affiliation><nlm:affiliation>Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Center for Air Pollution Research (CAPR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran.</nlm:affiliation></affiliation></author><author><name sortKey="Zendehdel, Kazem" sort="Zendehdel, Kazem" uniqKey="Zendehdel K" first="Kazem" last="Zendehdel">Kazem Zendehdel</name><affiliation><nlm:affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Breast Diseases Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Archives of Iranian medicine</title><idno type="eISSN">1735-3947</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Aged (MeSH)</term><term>COVID-19 (diagnosis)</term><term>COVID-19 (drug therapy)</term><term>COVID-19 (mortality)</term><term>COVID-19 (physiopathology)</term><term>COVID-19 Nucleic Acid Testing (standards)</term><term>COVID-19 Nucleic Acid Testing (statistics & numerical data)</term><term>Comorbidity (MeSH)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Hydroxychloroquine (therapeutic use)</term><term>Intensive Care Units (statistics & numerical data)</term><term>Iran (epidemiology)</term><term>Length of Stay (statistics & numerical data)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Respiration, Artificial (adverse effects)</term><term>Retrospective Studies (MeSH)</term><term>SARS-CoV-2 (MeSH)</term><term>Severity of Illness Index (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Iran</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Respiration, Artificial</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>COVID-19</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>COVID-19 Nucleic Acid Testing</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>COVID-19 Nucleic Acid Testing</term><term>Intensive Care Units</term><term>Length of Stay</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Comorbidity</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term><term>Retrospective Studies</term><term>SARS-CoV-2</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>We studied the clinical characteristics and outcomes of 905 hospitalized coronavirus disease 2019 (COVID-19) patients admitted to Imam Khomeini Hospital Complex (IKHC), Tehran, Iran.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>COVID-19 patients were recruited based on clinical symptoms and patterns of computed tomography (CT) imaging between February 20 and March 19. All patients were tested for the presence of COVID-19 RNA. The Poisson regression model estimated the incidence rate ratio (IRR) for different parameters.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>The average age (± standard deviation) was 56.9 (±15.7) years and 61.77% were male. The most common symptoms were fever (93.59%), dry cough (79.78%), and dyspnea (75.69%). Only 43.76% of patients were positive for the RT-PCR COVID-19 test. Prevalence of lymphopenia was 42.9% and more than 90% had elevated lactate dehydrogenase (LDH) or C-reactive protein (CRP). About 11% were severe cases, and 13.7% died in the hospital. The median length of stay (LOS) was 3 days. We found higher risks of mortality in patients who were older than 70 years (IRR = 11.77, 95% CI 3.63-38.18), underwent mechanical ventilation (IRR = 7.36, 95% CI 5.06-10.7), were admitted to the intensive care unit (ICU) (IRR = 5.47, 95% CI 4.00-8.38), tested positive on the COVID-19 test (IRR = 2.80, 95% CI 1.64-3.55), and reported a history of comorbidity (IRR = 1.76, 95% CI 1.07-2.89) compared to their corresponding reference groups. Hydroxychloroquine therapy was not associated with mortality in our study.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Older age, experiencing a severe form of the disease, and having a comorbidity were the most important prognostic factors for COVID-19 infection. Larger studies are needed to perform further subgroup analyses and verify high-risk groups.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">33220695</PMID><DateCompleted><Year>2020</Year><Month>12</Month><Day>10</Day></DateCompleted><DateRevised><Year>2020</Year><Month>12</Month><Day>14</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1735-3947</ISSN><JournalIssue CitedMedium="Internet"><Volume>23</Volume><Issue>11</Issue><PubDate><Year>2020</Year><Month>11</Month><Day>01</Day></PubDate></JournalIssue><Title>Archives of Iranian medicine</Title><ISOAbbreviation>Arch Iran Med</ISOAbbreviation></Journal><ArticleTitle>Clinical Characteristics and Outcomes of 905 COVID-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran.</ArticleTitle><Pagination><MedlinePgn>766-775</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.34172/aim.2020.102</ELocationID><Abstract><AbstractText Label="BACKGROUND">We studied the clinical characteristics and outcomes of 905 hospitalized coronavirus disease 2019 (COVID-19) patients admitted to Imam Khomeini Hospital Complex (IKHC), Tehran, Iran.</AbstractText><AbstractText Label="METHODS">COVID-19 patients were recruited based on clinical symptoms and patterns of computed tomography (CT) imaging between February 20 and March 19. All patients were tested for the presence of COVID-19 RNA. The Poisson regression model estimated the incidence rate ratio (IRR) for different parameters.</AbstractText><AbstractText Label="RESULTS">The average age (± standard deviation) was 56.9 (±15.7) years and 61.77% were male. The most common symptoms were fever (93.59%), dry cough (79.78%), and dyspnea (75.69%). Only 43.76% of patients were positive for the RT-PCR COVID-19 test. Prevalence of lymphopenia was 42.9% and more than 90% had elevated lactate dehydrogenase (LDH) or C-reactive protein (CRP). About 11% were severe cases, and 13.7% died in the hospital. The median length of stay (LOS) was 3 days. We found higher risks of mortality in patients who were older than 70 years (IRR = 11.77, 95% CI 3.63-38.18), underwent mechanical ventilation (IRR = 7.36, 95% CI 5.06-10.7), were admitted to the intensive care unit (ICU) (IRR = 5.47, 95% CI 4.00-8.38), tested positive on the COVID-19 test (IRR = 2.80, 95% CI 1.64-3.55), and reported a history of comorbidity (IRR = 1.76, 95% CI 1.07-2.89) compared to their corresponding reference groups. Hydroxychloroquine therapy was not associated with mortality in our study.</AbstractText><AbstractText Label="CONCLUSION">Older age, experiencing a severe form of the disease, and having a comorbidity were the most important prognostic factors for COVID-19 infection. Larger studies are needed to perform further subgroup analyses and verify high-risk groups.</AbstractText><CopyrightInformation>© 2020 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Allameh</LastName><ForeName>Seyed Farshad</ForeName><Initials>SF</Initials><AffiliationInfo><Affiliation>Gastroenterology Ward, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nemati</LastName><ForeName>Saeed</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ghalehtaki</LastName><ForeName>Reza</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mohammadnejad</LastName><ForeName>Esmaeil</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Department of Medical-Surgical Nursing and Basic Sciences, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aghili</LastName><ForeName>Seyed Mojtaba</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Department of Emergency Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khajavirad</LastName><ForeName>Nasim</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Beigmohammadi</LastName><ForeName>Mohammad-Taghi</ForeName><Initials>MT</Initials><AffiliationInfo><Affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Salehi</LastName><ForeName>Mohammadreza</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mirfazaelian</LastName><ForeName>Hadi</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Edalatifard</LastName><ForeName>Maryam</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Pulmonology, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kazemizadeh</LastName><ForeName>Hossein</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Pulmonology, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dehghan Manshadi</LastName><ForeName>Seyed Ali</ForeName><Initials>SA</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hasannezhad</LastName><ForeName>Maliheh</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases and Tropical Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Amoozadeh</LastName><ForeName>Laya</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Radnia</LastName><ForeName>Masoud</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Imam Khomeini Hospital Complex (IKHC), Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khatami</LastName><ForeName>Seyedeh Rana</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nahvijou</LastName><ForeName>Azin</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Seyyedsalehi</LastName><ForeName>Monireh Sadat</ForeName><Initials>MS</Initials><AffiliationInfo><Affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rashidian</LastName><ForeName>Laleh</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ayoobi Yazdi</LastName><ForeName>Niloofar</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nasiri Toosi</LastName><ForeName>Mohsen</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sadeghniiat-Haghighi</LastName><ForeName>Khosro</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Occupational Sleep Research Center, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jafarian</LastName><ForeName>Ali</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Liver Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Hepatobiliary Surgery and Liver Transplantation Division, Department of General Surgery, Imam Khomeini Hospital Complex, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yunesian</LastName><ForeName>Masud</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Center for Air Pollution Research (CAPR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zendehdel</LastName><ForeName>Kazem</ForeName><Initials>K</Initials><Identifier Source="ORCID">0000-0002-0269-4945</Identifier><AffiliationInfo><Affiliation>Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Breast Diseases Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>11</Month><Day>01</Day></ArticleDate></Article><MedlineJournalInfo><Country>Iran</Country><MedlineTA>Arch Iran Med</MedlineTA><NlmUniqueID>100889644</NlmUniqueID><ISSNLinking>1029-2977</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber><NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="N">COVID-19</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000087123" MajorTopicYN="N">COVID-19 Nucleic Acid Testing</DescriptorName><QualifierName UI="Q000592" MajorTopicYN="N">standards</QualifierName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015897" MajorTopicYN="N">Comorbidity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007362" MajorTopicYN="N">Intensive Care Units</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007492" MajorTopicYN="N" Type="Geographic">Iran</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007902" MajorTopicYN="N">Length of Stay</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012121" MajorTopicYN="N">Respiration, Artificial</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000086402" MajorTopicYN="N">SARS-CoV-2</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Clinical characteristics</Keyword><Keyword MajorTopicYN="Y">Iran</Keyword><Keyword MajorTopicYN="Y">Mortality</Keyword><Keyword MajorTopicYN="Y">Outcome</Keyword><Keyword MajorTopicYN="Y">SARS-CoV-2</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>05</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>09</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>11</Month><Day>22</Day><Hour>20</Hour><Minute>25</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>11</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>12</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33220695</ArticleId><ArticleId IdType="doi">10.34172/aim.2020.102</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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