A case of severe course of COVID-19 treated with experimental therapy.
Identifieur interne : 000700 ( Main/Corpus ); précédent : 000699; suivant : 000701A case of severe course of COVID-19 treated with experimental therapy.
Auteurs : Milan Zlámal ; Katarína Št Chovská ; Michal HolubSource :
- Casopis lekaru ceskych [ 0008-7335 ] ; 2020.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antiviral Agents, Azithromycin, Hydroxychloroquine.
- therapy : COVID-19.
- Aged, Humans, Immunization, Passive, Pandemics, SARS-CoV-2, Therapies, Investigational.
Abstract
70-year-old high-risk patient with severe course of COVID-19 hospitalized for progressive dyspnea due to extensive bilateral pneumonia caused by SARS-CoV-2. The patient was treated with hydroxychloroquine and azithromycin from day one of hospital stay. Because of progression on the therapy, the convalescent plasma was administered on day three of hospitalization. The patient subsequently improved and was discharged home on day eleven of the hospital stay. Risk factors of severe course of the infection, complications and potential therapies of COVID-19 are discussed.
PubMed: 33297704
Links to Exploration step
pubmed:33297704Le document en format XML
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<author><name sortKey="Zlamal, Milan" sort="Zlamal, Milan" uniqKey="Zlamal M" first="Milan" last="Zlámal">Milan Zlámal</name>
</author>
<author><name sortKey="St Chovska, Katarina" sort="St Chovska, Katarina" uniqKey="St Chovska K" first="Katarína" last="Št Chovská">Katarína Št Chovská</name>
</author>
<author><name sortKey="Holub, Michal" sort="Holub, Michal" uniqKey="Holub M" first="Michal" last="Holub">Michal Holub</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">A case of severe course of COVID-19 treated with experimental therapy.</title>
<author><name sortKey="Zlamal, Milan" sort="Zlamal, Milan" uniqKey="Zlamal M" first="Milan" last="Zlámal">Milan Zlámal</name>
</author>
<author><name sortKey="St Chovska, Katarina" sort="St Chovska, Katarina" uniqKey="St Chovska K" first="Katarína" last="Št Chovská">Katarína Št Chovská</name>
</author>
<author><name sortKey="Holub, Michal" sort="Holub, Michal" uniqKey="Holub M" first="Michal" last="Holub">Michal Holub</name>
</author>
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<series><title level="j">Casopis lekaru ceskych</title>
<idno type="ISSN">0008-7335</idno>
<imprint><date when="2020" type="published">2020</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Antiviral Agents (therapeutic use)</term>
<term>Azithromycin (therapeutic use)</term>
<term>COVID-19 (therapy)</term>
<term>Humans (MeSH)</term>
<term>Hydroxychloroquine (therapeutic use)</term>
<term>Immunization, Passive (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>SARS-CoV-2 (MeSH)</term>
<term>Therapies, Investigational (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term>
<term>Azithromycin</term>
<term>Hydroxychloroquine</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>COVID-19</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Humans</term>
<term>Immunization, Passive</term>
<term>Pandemics</term>
<term>SARS-CoV-2</term>
<term>Therapies, Investigational</term>
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<front><div type="abstract" xml:lang="en">70-year-old high-risk patient with severe course of COVID-19 hospitalized for progressive dyspnea due to extensive bilateral pneumonia caused by SARS-CoV-2. The patient was treated with hydroxychloroquine and azithromycin from day one of hospital stay. Because of progression on the therapy, the convalescent plasma was administered on day three of hospitalization. The patient subsequently improved and was discharged home on day eleven of the hospital stay. Risk factors of severe course of the infection, complications and potential therapies of COVID-19 are discussed.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Automated" Owner="NLM"><PMID Version="1">33297704</PMID>
<DateCompleted><Year>2020</Year>
<Month>12</Month>
<Day>11</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>12</Month>
<Day>14</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0008-7335</ISSN>
<JournalIssue CitedMedium="Print"><Volume>159</Volume>
<Issue>5</Issue>
<PubDate><Year>2020</Year>
<Season>Summer</Season>
</PubDate>
</JournalIssue>
<Title>Casopis lekaru ceskych</Title>
<ISOAbbreviation>Cas Lek Cesk</ISOAbbreviation>
</Journal>
<ArticleTitle>A case of severe course of COVID-19 treated with experimental therapy.</ArticleTitle>
<Pagination><MedlinePgn>181-184</MedlinePgn>
</Pagination>
<Abstract><AbstractText>70-year-old high-risk patient with severe course of COVID-19 hospitalized for progressive dyspnea due to extensive bilateral pneumonia caused by SARS-CoV-2. The patient was treated with hydroxychloroquine and azithromycin from day one of hospital stay. Because of progression on the therapy, the convalescent plasma was administered on day three of hospitalization. The patient subsequently improved and was discharged home on day eleven of the hospital stay. Risk factors of severe course of the infection, complications and potential therapies of COVID-19 are discussed.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zlámal</LastName>
<ForeName>Milan</ForeName>
<Initials>M</Initials>
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<Author ValidYN="Y"><LastName>Štěchovská</LastName>
<ForeName>Katarína</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Holub</LastName>
<ForeName>Michal</ForeName>
<Initials>M</Initials>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
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<VernacularTitle>Případ těžkého průběhu onemocnění COVID-19 u vysoce rizikového 70letého muže.</VernacularTitle>
</Article>
<MedlineJournalInfo><Country>Czech Republic</Country>
<MedlineTA>Cas Lek Cesk</MedlineTA>
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<Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber>
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<SupplMeshList><SupplMeshName Type="Protocol" UI="C000705128">COVID-19 serotherapy</SupplMeshName>
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<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D000086382" MajorTopicYN="Y">COVID-19</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
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<MeshHeading><DescriptorName UI="D007116" MajorTopicYN="N">Immunization, Passive</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
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<MeshHeading><DescriptorName UI="D000086402" MajorTopicYN="N">SARS-CoV-2</DescriptorName>
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<MeshHeading><DescriptorName UI="D035703" MajorTopicYN="N">Therapies, Investigational</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword>
<Keyword MajorTopicYN="N">SARS-CoV-2</Keyword>
<Keyword MajorTopicYN="N">azithromycin</Keyword>
<Keyword MajorTopicYN="N">blood plasma</Keyword>
<Keyword MajorTopicYN="N">hydroxychloroquine</Keyword>
<Keyword MajorTopicYN="N">viral pneumonia</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>12</Month>
<Day>10</Day>
<Hour>5</Hour>
<Minute>33</Minute>
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<PubMedPubDate PubStatus="pubmed"><Year>2020</Year>
<Month>12</Month>
<Day>11</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2020</Year>
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<PublicationStatus>ppublish</PublicationStatus>
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