Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine.
Identifieur interne : 000414 ( Main/Corpus ); précédent : 000413; suivant : 000415Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine.
Auteurs : Francisco Tejada Cifuentes ; Ángeles Lloret Callejo ; María José Tirado Peláez ; Olga Rubio Pulido ; Marta Ruiz-Morote Arag N ; Rocío Fernández Urrusuno ; María Isabel Mu Oz Carreras ; María Isabel Méndez Esteban ; Victoria Maestre Sánchez ; Antonio García Bonilla ; José Manuel Paredero Dominguez ; Virginia Arroyo Pineda ; Esther Marco Tej N ; Gregorio Romero Candel ; Ana Isabel Fernández Marchante ; José Marco Del Rio ; Teresa Ortiz Martín ; Piedad L Pez SánchezSource :
- Medicina clinica (English ed.) [ 2387-0206 ] ; 2021.
Abstract
Objective
To analyze the incidence of Covid-19 in patients who are chronic users of hydroxychloroquine.
Patients and methods
Cross-sectional retrospective observational multicenter study in health areas and districts from Castilla La-Mancha and Andalucia. Of the 4451 participants included in the first recruitment, 3817 with valid data were selected. The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. Sociodemographic and clinical variables and treatment and concomitant comorbidities were recorded.
Results
169 (4,45%) patients had Covid-19 infection, of which 12 (7.1 %) died and 32 (18.9%) required hospital admission. Previous respiratory pathology was related to Covid-19 infection (
Conclusion
There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19.
DOI: 10.1016/j.medcle.2020.10.012
PubMed: 33521293
PubMed Central: PMC7825965
Links to Exploration step
pubmed:33521293Le document en format XML
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de Atención Integrada de Albacete, Albacete, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Rubio Pulido, Olga" sort="Rubio Pulido, Olga" uniqKey="Rubio Pulido O" first="Olga" last="Rubio Pulido">Olga Rubio Pulido</name><affiliation><nlm:affiliation>Gerencia de Atención Primaria de Toledo, Toledo, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Ruiz Morote Arag N, Marta" sort="Ruiz Morote Arag N, Marta" uniqKey="Ruiz Morote Arag N M" first="Marta" last="Ruiz-Morote Arag N">Marta Ruiz-Morote Arag N</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Puertollano, Puertollan, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandez Urrusuno, Rocio" sort="Fernandez Urrusuno, Rocio" uniqKey="Fernandez Urrusuno R" first="Rocío" last="Fernández Urrusuno">Rocío Fernández Urrusuno</name><affiliation><nlm:affiliation>Distrito Sanitario Aljarafe, Sevilla, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Mu Oz Carreras, Maria Isabel" sort="Mu Oz Carreras, Maria Isabel" uniqKey="Mu Oz Carreras M" first="María Isabel" last="Mu Oz Carreras">María Isabel Mu Oz Carreras</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada, Alcázar de San Juan, Alcázar de San Juan, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Mendez Esteban, Maria Isabel" sort="Mendez Esteban, Maria Isabel" uniqKey="Mendez Esteban M" first="María Isabel" last="Méndez Esteban">María Isabel Méndez Esteban</name><affiliation><nlm:affiliation>Área de Gestión Sanitaria Campo de Gibraltar, Cádiz, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Maestre Sanchez, Victoria" sort="Maestre Sanchez, Victoria" uniqKey="Maestre Sanchez V" first="Victoria" last="Maestre Sánchez">Victoria Maestre Sánchez</name><affiliation><nlm:affiliation>Distrito Sanitario Condado Campiña, Huelva, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Garcia Bonilla, Antonio" sort="Garcia Bonilla, Antonio" uniqKey="Garcia Bonilla A" first="Antonio" last="García Bonilla">Antonio García Bonilla</name><affiliation><nlm:affiliation>Área de Gestión Sanitaria Jerez, Costa Noroeste y Sierra de Cádiz, Jerez, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Paredero Dominguez, Jose Manuel" sort="Paredero Dominguez, Jose Manuel" uniqKey="Paredero Dominguez J" first="José Manuel" last="Paredero Dominguez">José Manuel Paredero Dominguez</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada, de Guadalajara, Guadalajara, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Arroyo Pineda, Virginia" sort="Arroyo Pineda, Virginia" uniqKey="Arroyo Pineda V" first="Virginia" last="Arroyo Pineda">Virginia Arroyo Pineda</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada Talavera de la Reina, Talavera de la Reina, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Marco Tej N, Esther" sort="Marco Tej N, Esther" uniqKey="Marco Tej N E" first="Esther" last="Marco Tej N">Esther Marco Tej N</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Cuenca, Cuenca, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Romero Candel, Gregorio" sort="Romero Candel, Gregorio" uniqKey="Romero Candel G" first="Gregorio" last="Romero Candel">Gregorio Romero Candel</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Hellín, Hellín, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandez Marchante, Ana Isabel" sort="Fernandez Marchante, Ana Isabel" uniqKey="Fernandez Marchante A" first="Ana Isabel" last="Fernández Marchante">Ana Isabel Fernández Marchante</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Villarrobledo, Villarrobledo, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Marco Del Rio, Jose" sort="Marco Del Rio, Jose" uniqKey="Marco Del Rio J" first="José" last="Marco Del Rio">José Marco Del Rio</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Almansa, Almansa, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Ortiz Martin, Teresa" sort="Ortiz Martin, Teresa" uniqKey="Ortiz Martin T" first="Teresa" last="Ortiz Martín">Teresa Ortiz Martín</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Valdepeñas, Valdepeñas, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="L Pez Sanchez, Piedad" sort="L Pez Sanchez, Piedad" uniqKey="L Pez Sanchez P" first="Piedad" last="L Pez Sánchez">Piedad L Pez Sánchez</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Tomelloso, Tomelloso, Spain.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2021">2021</date><idno type="RBID">pubmed:33521293</idno><idno type="pmid">33521293</idno><idno type="doi">10.1016/j.medcle.2020.10.012</idno><idno type="pmc">PMC7825965</idno><idno type="wicri:Area/Main/Corpus">000414</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000414</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine.</title><author><name sortKey="Tejada Cifuentes, Francisco" sort="Tejada Cifuentes, Francisco" uniqKey="Tejada Cifuentes F" first="Francisco" last="Tejada Cifuentes">Francisco Tejada Cifuentes</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Albacete, Albacete, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Lloret Callejo, Angeles" sort="Lloret Callejo, Angeles" uniqKey="Lloret Callejo A" first="Ángeles" last="Lloret Callejo">Ángeles Lloret Callejo</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Albacete, Albacete, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Tirado Pelaez, Maria Jose" sort="Tirado Pelaez, Maria Jose" uniqKey="Tirado Pelaez M" first="María José" last="Tirado Peláez">María José Tirado Peláez</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Albacete, Albacete, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Rubio Pulido, Olga" sort="Rubio Pulido, Olga" uniqKey="Rubio Pulido O" first="Olga" last="Rubio Pulido">Olga Rubio Pulido</name><affiliation><nlm:affiliation>Gerencia de Atención Primaria de Toledo, Toledo, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Ruiz Morote Arag N, Marta" sort="Ruiz Morote Arag N, Marta" uniqKey="Ruiz Morote Arag N M" first="Marta" last="Ruiz-Morote Arag N">Marta Ruiz-Morote Arag N</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Puertollano, Puertollan, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandez Urrusuno, Rocio" sort="Fernandez Urrusuno, Rocio" uniqKey="Fernandez Urrusuno R" first="Rocío" last="Fernández Urrusuno">Rocío Fernández Urrusuno</name><affiliation><nlm:affiliation>Distrito Sanitario Aljarafe, Sevilla, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Mu Oz Carreras, Maria Isabel" sort="Mu Oz Carreras, Maria Isabel" uniqKey="Mu Oz Carreras M" first="María Isabel" last="Mu Oz Carreras">María Isabel Mu Oz Carreras</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada, Alcázar de San Juan, Alcázar de San Juan, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Mendez Esteban, Maria Isabel" sort="Mendez Esteban, Maria Isabel" uniqKey="Mendez Esteban M" first="María Isabel" last="Méndez Esteban">María Isabel Méndez Esteban</name><affiliation><nlm:affiliation>Área de Gestión Sanitaria Campo de Gibraltar, Cádiz, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Maestre Sanchez, Victoria" sort="Maestre Sanchez, Victoria" uniqKey="Maestre Sanchez V" first="Victoria" last="Maestre Sánchez">Victoria Maestre Sánchez</name><affiliation><nlm:affiliation>Distrito Sanitario Condado Campiña, Huelva, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Garcia Bonilla, Antonio" sort="Garcia Bonilla, Antonio" uniqKey="Garcia Bonilla A" first="Antonio" last="García Bonilla">Antonio García Bonilla</name><affiliation><nlm:affiliation>Área de Gestión Sanitaria Jerez, Costa Noroeste y Sierra de Cádiz, Jerez, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Paredero Dominguez, Jose Manuel" sort="Paredero Dominguez, Jose Manuel" uniqKey="Paredero Dominguez J" first="José Manuel" last="Paredero Dominguez">José Manuel Paredero Dominguez</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada, de Guadalajara, Guadalajara, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Arroyo Pineda, Virginia" sort="Arroyo Pineda, Virginia" uniqKey="Arroyo Pineda V" first="Virginia" last="Arroyo Pineda">Virginia Arroyo Pineda</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada Talavera de la Reina, Talavera de la Reina, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Marco Tej N, Esther" sort="Marco Tej N, Esther" uniqKey="Marco Tej N E" first="Esther" last="Marco Tej N">Esther Marco Tej N</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Cuenca, Cuenca, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Romero Candel, Gregorio" sort="Romero Candel, Gregorio" uniqKey="Romero Candel G" first="Gregorio" last="Romero Candel">Gregorio Romero Candel</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Hellín, Hellín, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Fernandez Marchante, Ana Isabel" sort="Fernandez Marchante, Ana Isabel" uniqKey="Fernandez Marchante A" first="Ana Isabel" last="Fernández Marchante">Ana Isabel Fernández Marchante</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Villarrobledo, Villarrobledo, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Marco Del Rio, Jose" sort="Marco Del Rio, Jose" uniqKey="Marco Del Rio J" first="José" last="Marco Del Rio">José Marco Del Rio</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Almansa, Almansa, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="Ortiz Martin, Teresa" sort="Ortiz Martin, Teresa" uniqKey="Ortiz Martin T" first="Teresa" last="Ortiz Martín">Teresa Ortiz Martín</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Valdepeñas, Valdepeñas, Spain.</nlm:affiliation></affiliation></author><author><name sortKey="L Pez Sanchez, Piedad" sort="L Pez Sanchez, Piedad" uniqKey="L Pez Sanchez P" first="Piedad" last="L Pez Sánchez">Piedad L Pez Sánchez</name><affiliation><nlm:affiliation>Gerencia de Atención Integrada de Tomelloso, Tomelloso, Spain.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Medicina clinica (English ed.)</title><idno type="eISSN">2387-0206</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>Objective</b></p><p>To analyze the incidence of Covid-19 in patients who are chronic users of hydroxychloroquine.</p></div><div type="abstract" xml:lang="en"><p><b>Patients and methods</b></p><p>Cross-sectional retrospective observational multicenter study in health areas and districts from Castilla La-Mancha and Andalucia. Of the 4451 participants included in the first recruitment, 3817 with valid data were selected. The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. Sociodemographic and clinical variables and treatment and concomitant comorbidities were recorded.</p></div><div type="abstract" xml:lang="en"><p><b>Results</b></p><p>169 (4,45%) patients had Covid-19 infection, of which 12 (7.1 %) died and 32 (18.9%) required hospital admission. Previous respiratory pathology was related to Covid-19 infection (</p></div><div type="abstract" xml:lang="en"><p><b>Conclusion</b></p><p>There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19.</p></div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">33521293</PMID><DateRevised><Year>2021</Year><Month>02</Month><Day>17</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2387-0206</ISSN><JournalIssue CitedMedium="Internet"><Volume>156</Volume><Issue>4</Issue><PubDate><Year>2021</Year><Month>Feb</Month><Day>26</Day></PubDate></JournalIssue><Title>Medicina clinica (English ed.)</Title><ISOAbbreviation>Med Clin (Engl Ed)</ISOAbbreviation></Journal><ArticleTitle>Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine.</ArticleTitle><Pagination><MedlinePgn>166-171</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.medcle.2020.10.012</ELocationID><Abstract><AbstractText Label="Objective" NlmCategory="UNASSIGNED">To analyze the incidence of Covid-19 in patients who are chronic users of hydroxychloroquine.</AbstractText><AbstractText Label="Patients and methods" NlmCategory="UNASSIGNED">Cross-sectional retrospective observational multicenter study in health areas and districts from Castilla La-Mancha and Andalucia. Of the 4451 participants included in the first recruitment, 3817 with valid data were selected. The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. Sociodemographic and clinical variables and treatment and concomitant comorbidities were recorded.</AbstractText><AbstractText Label="Results" NlmCategory="UNASSIGNED">169 (4,45%) patients had Covid-19 infection, of which 12 (7.1 %) died and 32 (18.9%) required hospital admission. Previous respiratory pathology was related to Covid-19 infection (<i>P</i> < .05). Maculopathy appears in 5.3% of patients and is significantly related to the dose of hydroxychloroquine consumed (<i>P</i> < .05).</AbstractText><AbstractText Label="Conclusion" NlmCategory="UNASSIGNED">There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19.</AbstractText><CopyrightInformation>© 2020 Elsevier España, S.L.U. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tejada Cifuentes</LastName><ForeName>Francisco</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Albacete, Albacete, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lloret Callejo</LastName><ForeName>Ángeles</ForeName><Initials>Á</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Albacete, Albacete, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tirado Peláez</LastName><ForeName>María José</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Albacete, Albacete, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rubio Pulido</LastName><ForeName>Olga</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Primaria de Toledo, Toledo, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ruiz-Morote Aragón</LastName><ForeName>Marta</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Puertollano, Puertollan, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernández Urrusuno</LastName><ForeName>Rocío</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Distrito Sanitario Aljarafe, Sevilla, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Muñoz Carreras</LastName><ForeName>María Isabel</ForeName><Initials>MI</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada, Alcázar de San Juan, Alcázar de San Juan, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Méndez Esteban</LastName><ForeName>María Isabel</ForeName><Initials>MI</Initials><AffiliationInfo><Affiliation>Área de Gestión Sanitaria Campo de Gibraltar, Cádiz, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maestre Sánchez</LastName><ForeName>Victoria</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Distrito Sanitario Condado Campiña, Huelva, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>García Bonilla</LastName><ForeName>Antonio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Área de Gestión Sanitaria Jerez, Costa Noroeste y Sierra de Cádiz, Jerez, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paredero Dominguez</LastName><ForeName>José Manuel</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada, de Guadalajara, Guadalajara, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arroyo Pineda</LastName><ForeName>Virginia</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada Talavera de la Reina, Talavera de la Reina, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marco Tejón</LastName><ForeName>Esther</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Cuenca, Cuenca, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Romero Candel</LastName><ForeName>Gregorio</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Hellín, Hellín, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fernández Marchante</LastName><ForeName>Ana Isabel</ForeName><Initials>AI</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Villarrobledo, Villarrobledo, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marco Del Rio</LastName><ForeName>José</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Almansa, Almansa, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ortiz Martín</LastName><ForeName>Teresa</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Valdepeñas, Valdepeñas, Spain.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>López Sánchez</LastName><ForeName>Piedad</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Gerencia de Atención Integrada de Tomelloso, Tomelloso, Spain.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2021</Year><Month>01</Month><Day>23</Day></ArticleDate></Article><MedlineJournalInfo><Country>Spain</Country><MedlineTA>Med Clin (Engl Ed)</MedlineTA><NlmUniqueID>101711190</NlmUniqueID><ISSNLinking>2387-0206</ISSNLinking></MedlineJournalInfo><OtherAbstract Type="Publisher" Language="spa"><AbstractText Label="Objetivo" NlmCategory="UNASSIGNED">Analizar la incidencia de la enfermedad del coronavirus 19 (COVID-19) en pacientes consumidores crónicos de hidroxicloroquina.</AbstractText><AbstractText Label="Pacientes y métodos" NlmCategory="UNASSIGNED">Estudio multicéntrico observacional retrospectivo transversal en Áreas de Salud de Castilla La-Mancha y distritos sanitarios de Andalucía. De los 4.451 participantes incluidos en el primer reclutamiento se seleccionaron 3.817 sujetos con datos válidos. La variable principal del estudio ha sido la presencia o ausencia de infección por la COVID-19 por diagnóstico clínico, serológico o por reacción en cadena de la polimerasa. Se registraron variables sociodemográficas, clínicas y tratamientos y comorbilidades concomitantes.</AbstractText><AbstractText Label="Resultados" NlmCategory="UNASSIGNED">Ciento sesenta y nueve (4,45%) pacientes presentaron infección por la COVID-19, de los cuales fallecieron 12 (7,1%) y 32 (18,9%) requirieron ingreso hospitalario. La enfermedad respiratoria previa se relacionó con la infección por la COVID-19 (p < 0,05). La maculopatía aparece en un 5,3% de los pacientes y está relacionada significativamente con la dosis de hidroxicloroquina consumida (p < 0,05).</AbstractText><AbstractText Label="Conclusión" NlmCategory="UNASSIGNED">No existe relación entre consumo crónico de hidroxicloroquina e incidencia de la COVID-19.</AbstractText></OtherAbstract><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Coronavirus</Keyword><Keyword MajorTopicYN="N">Hydroxychloroquine</Keyword><Keyword MajorTopicYN="N">Incidence</Keyword><Keyword MajorTopicYN="N">Treatment</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>08</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>10</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2021</Year><Month>2</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>2</Month><Day>2</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>2</Month><Day>1</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33521293</ArticleId><ArticleId IdType="doi">10.1016/j.medcle.2020.10.012</ArticleId><ArticleId IdType="pii">S2387-0206(21)00020-6</ArticleId><ArticleId IdType="pmc">PMC7825965</ArticleId></ArticleIdList><pmc-dir>pmcsd</pmc-dir>
<ReferenceList><Reference><Citation>Clin Infect Dis. 2020 Jul 28;71(15):732-739</Citation><ArticleIdList><ArticleId IdType="pubmed">32150618</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Infect Dis. 2020 Apr 27;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32338708</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2020 May 16;395(10236):1569-1578</Citation><ArticleIdList><ArticleId IdType="pubmed">32423584</ArticleId></ArticleIdList></Reference><Reference><Citation>Aust Prescr. 2020 Jun;43(3):76-77</Citation><ArticleIdList><ArticleId IdType="pubmed">32675906</ArticleId></ArticleIdList></Reference><Reference><Citation>Diabetes Metab Syndr. 2020 Jul - Aug;14(4):589-596</Citation><ArticleIdList><ArticleId IdType="pubmed">32417708</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Ethics. 2020 Sep;46(9):574-578</Citation><ArticleIdList><ArticleId IdType="pubmed">32647045</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Nov 19;383(21):2041-2052</Citation><ArticleIdList><ArticleId IdType="pubmed">32706953</ArticleId></ArticleIdList></Reference><Reference><Citation>CMAJ. 2020 Jul 6;192(27):E756-E767</Citation><ArticleIdList><ArticleId IdType="pubmed">32409522</ArticleId></ArticleIdList></Reference><Reference><Citation>BMJ. 2020 May 14;369:m1849</Citation><ArticleIdList><ArticleId IdType="pubmed">32409561</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2020 May 30;395(10238):1705-1714</Citation><ArticleIdList><ArticleId IdType="pubmed">32416785</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Environ Res Public Health. 2020 Jul 17;17(14):</Citation><ArticleIdList><ArticleId IdType="pubmed">32709002</ArticleId></ArticleIdList></Reference><Reference><Citation>CMAJ. 2020 Apr 27;192(17):E450-E453</Citation><ArticleIdList><ArticleId IdType="pubmed">32269021</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Intern Med. 2020 Aug 18;173(4):287-296</Citation><ArticleIdList><ArticleId IdType="pubmed">32459529</ArticleId></ArticleIdList></Reference><Reference><Citation>Circulation. 2020 Jun 16;141(24):e906-e907</Citation><ArticleIdList><ArticleId IdType="pubmed">32267732</ArticleId></ArticleIdList></Reference><Reference><Citation>Ophthalmology. 2011 Feb;118(2):415-22</Citation><ArticleIdList><ArticleId IdType="pubmed">21292109</ArticleId></ArticleIdList></Reference><Reference><Citation>Microb Pathog. 2020 Aug;145:104228</Citation><ArticleIdList><ArticleId IdType="pubmed">32344177</ArticleId></ArticleIdList></Reference><Reference><Citation>J Crit Care. 2020 Jun;57:279-283</Citation><ArticleIdList><ArticleId IdType="pubmed">32173110</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Respir Med. 2020 Apr;8(4):e21</Citation><ArticleIdList><ArticleId IdType="pubmed">32171062</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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