Current Overviews on COVID-19 Management Strategies.
Identifieur interne : 000040 ( Main/Corpus ); précédent : 000039; suivant : 000041Current Overviews on COVID-19 Management Strategies.
Auteurs : Pankaj Kumar Rai ; Zeba Mueed ; Abhiroop Chowdhury ; Ravi Deval ; Dinesh Kumar ; Mohammad A. Kamal ; Yogeshwar Singh Negi ; Shubhra Pareek ; Nitesh Kumar PoddarSource :
- Current pharmaceutical biotechnology [ 1873-4316 ] ; 2021.
Abstract
The coronavirus pandemic has hit the world lately and caused acute respiratory syndrome in humans. The causative agent of the disease was soon brought to focus by scientists as SARS-CoV-2 and later called a novel coronavirus by the general public. Due to the severity and rapid spread of the disease, WHO classifies the COVID-19 pandemic as the 6th public health emergency even after taking efforts like worldwide quarantine and restrictions. Since only symptomatic treatment is available, the best way to control the spread of the virus is by taking preventive measures. Various types of antigen/antibody detection kits and diagnostic methods are available for the diagnosis of COVID-19 patients. In recent years, various phytochemicals and repurposing drugs are showing a broad range of anti-viral activities with different modes of action have been identified. Repurposing drugs such as arbidol, hydroxychloroquine, chloroquine, lopinavir, favipiravir, remdesivir, hexamethylene amiloride, and dexamethasone, tocilizumab, interferon-β, neutralizing antibodies exhibit in vitro anti-coronaviral properties by inhibiting multiple processes in the virus life cycle. Various research groups are involved in drug trials and vaccine development. Plant-based anti-viral compounds such as baicalin, calanolides, curcumin, oxymatrine, matrine, and resveratrol exhibit different modes of action against a wide range of positive/negative sense-RNA/DNA virus, and future researches need to be conducted to ascertain their role, use in managing SARS-CoV-2. Thus, this article is an attempt to review the current understanding of COVID-19 acute respiratory disease and summarize its clinical features with their prospective control and various aspects of the therapeutic approach.
DOI: 10.2174/1389201022666210509022313
PubMed: 33966618
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Jindal Global University, Sonipat, Haryana, India.</nlm:affiliation></affiliation></author><author><name sortKey="Deval, Ravi" sort="Deval, Ravi" uniqKey="Deval R" first="Ravi" last="Deval">Ravi Deval</name><affiliation><nlm:affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</nlm:affiliation></affiliation></author><author><name sortKey="Kumar, Dinesh" sort="Kumar, Dinesh" uniqKey="Kumar D" first="Dinesh" last="Kumar">Dinesh Kumar</name><affiliation><nlm:affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</nlm:affiliation></affiliation></author><author><name sortKey="Kamal, Mohammad A" sort="Kamal, Mohammad A" uniqKey="Kamal M" first="Mohammad A" last="Kamal">Mohammad A. Kamal</name><affiliation><nlm:affiliation>West China School of Nursing / Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, Sichuan. 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Jindal Global University, Sonipat, Haryana, India.</nlm:affiliation></affiliation></author><author><name sortKey="Deval, Ravi" sort="Deval, Ravi" uniqKey="Deval R" first="Ravi" last="Deval">Ravi Deval</name><affiliation><nlm:affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</nlm:affiliation></affiliation></author><author><name sortKey="Kumar, Dinesh" sort="Kumar, Dinesh" uniqKey="Kumar D" first="Dinesh" last="Kumar">Dinesh Kumar</name><affiliation><nlm:affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</nlm:affiliation></affiliation></author><author><name sortKey="Kamal, Mohammad A" sort="Kamal, Mohammad A" uniqKey="Kamal M" first="Mohammad A" last="Kamal">Mohammad A. Kamal</name><affiliation><nlm:affiliation>West China School of Nursing / Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, Sichuan. China.</nlm:affiliation></affiliation></author><author><name sortKey="Negi, Yogeshwar Singh" sort="Negi, Yogeshwar Singh" uniqKey="Negi Y" first="Yogeshwar Singh" last="Negi">Yogeshwar Singh Negi</name><affiliation><nlm:affiliation>Department of Biosciences, Manipal University Jaipur, DehmiKalan, Jaipur-Ajmer Expressway, Jaipur-303007, Rajasthan, India.</nlm:affiliation></affiliation></author><author><name sortKey="Pareek, Shubhra" sort="Pareek, Shubhra" uniqKey="Pareek S" first="Shubhra" last="Pareek">Shubhra Pareek</name><affiliation><nlm:affiliation>Department of Chemistry, Manipal University Jaipur, DehmiKalan, Jaipur-Ajmer Expressway, Jaipur-303007, Rajasthan, India.</nlm:affiliation></affiliation></author><author><name sortKey="Poddar, Nitesh Kumar" sort="Poddar, Nitesh Kumar" uniqKey="Poddar N" first="Nitesh Kumar" last="Poddar">Nitesh Kumar Poddar</name><affiliation><nlm:affiliation>Department of Biosciences, Manipal University Jaipur, DehmiKalan, Jaipur-Ajmer Expressway, Jaipur-303007, Rajasthan, India.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Current pharmaceutical biotechnology</title><idno type="eISSN">1873-4316</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The coronavirus pandemic has hit the world lately and caused acute respiratory syndrome in humans. The causative agent of the disease was soon brought to focus by scientists as SARS-CoV-2 and later called a novel coronavirus by the general public. Due to the severity and rapid spread of the disease, WHO classifies the COVID-19 pandemic as the 6th public health emergency even after taking efforts like worldwide quarantine and restrictions. Since only symptomatic treatment is available, the best way to control the spread of the virus is by taking preventive measures. Various types of antigen/antibody detection kits and diagnostic methods are available for the diagnosis of COVID-19 patients. In recent years, various phytochemicals and repurposing drugs are showing a broad range of anti-viral activities with different modes of action have been identified. Repurposing drugs such as arbidol, hydroxychloroquine, chloroquine, lopinavir, favipiravir, remdesivir, hexamethylene amiloride, and dexamethasone, tocilizumab, interferon-β, neutralizing antibodies exhibit in vitro anti-coronaviral properties by inhibiting multiple processes in the virus life cycle. Various research groups are involved in drug trials and vaccine development. Plant-based anti-viral compounds such as baicalin, calanolides, curcumin, oxymatrine, matrine, and resveratrol exhibit different modes of action against a wide range of positive/negative sense-RNA/DNA virus, and future researches need to be conducted to ascertain their role, use in managing SARS-CoV-2. Thus, this article is an attempt to review the current understanding of COVID-19 acute respiratory disease and summarize its clinical features with their prospective control and various aspects of the therapeutic approach.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33966618</PMID><DateRevised><Year>2021</Year><Month>05</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-4316</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2021</Year><Month>May</Month><Day>08</Day></PubDate></JournalIssue><Title>Current pharmaceutical biotechnology</Title><ISOAbbreviation>Curr Pharm Biotechnol</ISOAbbreviation></Journal><ArticleTitle>Current Overviews on COVID-19 Management Strategies.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.2174/1389201022666210509022313</ELocationID><Abstract><AbstractText>The coronavirus pandemic has hit the world lately and caused acute respiratory syndrome in humans. The causative agent of the disease was soon brought to focus by scientists as SARS-CoV-2 and later called a novel coronavirus by the general public. Due to the severity and rapid spread of the disease, WHO classifies the COVID-19 pandemic as the 6th public health emergency even after taking efforts like worldwide quarantine and restrictions. Since only symptomatic treatment is available, the best way to control the spread of the virus is by taking preventive measures. Various types of antigen/antibody detection kits and diagnostic methods are available for the diagnosis of COVID-19 patients. In recent years, various phytochemicals and repurposing drugs are showing a broad range of anti-viral activities with different modes of action have been identified. Repurposing drugs such as arbidol, hydroxychloroquine, chloroquine, lopinavir, favipiravir, remdesivir, hexamethylene amiloride, and dexamethasone, tocilizumab, interferon-β, neutralizing antibodies exhibit in vitro anti-coronaviral properties by inhibiting multiple processes in the virus life cycle. Various research groups are involved in drug trials and vaccine development. Plant-based anti-viral compounds such as baicalin, calanolides, curcumin, oxymatrine, matrine, and resveratrol exhibit different modes of action against a wide range of positive/negative sense-RNA/DNA virus, and future researches need to be conducted to ascertain their role, use in managing SARS-CoV-2. Thus, this article is an attempt to review the current understanding of COVID-19 acute respiratory disease and summarize its clinical features with their prospective control and various aspects of the therapeutic approach.</AbstractText><CopyrightInformation>Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Rai</LastName><ForeName>Pankaj Kumar</ForeName><Initials>PK</Initials><AffiliationInfo><Affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mueed</LastName><ForeName>Zeba</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chowdhury</LastName><ForeName>Abhiroop</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>School of Environment & Sustainability, O.P. Jindal Global University, Sonipat, Haryana, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Deval</LastName><ForeName>Ravi</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kumar</LastName><ForeName>Dinesh</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Biotechnology, Invertis University, Bareilly, Uttar Pradesh, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kamal</LastName><ForeName>Mohammad A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>West China School of Nursing / Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, Sichuan. China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Negi</LastName><ForeName>Yogeshwar Singh</ForeName><Initials>YS</Initials><AffiliationInfo><Affiliation>Department of Biosciences, Manipal University Jaipur, DehmiKalan, Jaipur-Ajmer Expressway, Jaipur-303007, Rajasthan, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pareek</LastName><ForeName>Shubhra</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Chemistry, Manipal University Jaipur, DehmiKalan, Jaipur-Ajmer Expressway, Jaipur-303007, Rajasthan, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Poddar</LastName><ForeName>Nitesh Kumar</ForeName><Initials>NK</Initials><AffiliationInfo><Affiliation>Department of Biosciences, Manipal University Jaipur, DehmiKalan, Jaipur-Ajmer Expressway, Jaipur-303007, Rajasthan, India.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2021</Year><Month>05</Month><Day>08</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Curr Pharm Biotechnol</MedlineTA><NlmUniqueID>100960530</NlmUniqueID><ISSNLinking>1389-2010</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Diagnosis</Keyword><Keyword MajorTopicYN="N">Drug Targets</Keyword><Keyword MajorTopicYN="N">Epidemiology</Keyword><Keyword MajorTopicYN="N">SARS-CoV-2</Keyword><Keyword MajorTopicYN="N">Therapeutic</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>10</Month><Day>22</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2021</Year><Month>01</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2021</Year><Month>02</Month><Day>08</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2021</Year><Month>5</Month><Day>10</Day><Hour>5</Hour><Minute>59</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2021</Year><Month>5</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2021</Year><Month>5</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33966618</ArticleId><ArticleId IdType="pii">CPB-EPUB-115596</ArticleId><ArticleId IdType="doi">10.2174/1389201022666210509022313</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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