ChloroquineV1, an2020, Analysis, bibRecord, 000115

Measuring ACPA in the general population or primary care: is it useful?

Identifieur interne : 000115 ( an2020/Analysis ); précédent : 000114; suivant : 000116

Measuring ACPA in the general population or primary care: is it useful?

Auteurs : Axel Finckh ; Delphine Courvoisier ; Celine Lamacchia

Source :

RMD Open [ 2056-5933 ] ; 2020.

RBID : PMC:7046970

Abstract

Rheumatoid arthritis (RA) is associated with a significant disease burden and high costs for society. Because the disease has identifiable preclinical stages, screening and prevention have become a possibility in RA. Anticitrullinated peptide antibodies (ACPAs) are arguably the most likely candidate biomarker to screen for RA. This paper reviews the evidence for the use of ACPAs as a screening test in the broader general population, to identify individuals at high risk of subsequent onset of RA. We will review the diagnostic properties of the test and its positive and negative predictive value in different settings. We will discuss how ACPA testing could effectively be integrated in a broader screening strategy for RA.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046970

DOI: 10.1136/rmdopen-2019-001085
PubMed: 32079664
PubMed Central: 7046970

Affiliations:

Links to Exploration step

PMC:7046970

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p>Rheumatoid arthritis (RA) is associated with a significant disease burden and high costs for society. Because the disease has identifiable preclinical stages, screening and prevention have become a possibility in RA. Anticitrullinated peptide antibodies (ACPAs) are arguably the most likely candidate biomarker to screen for RA. This paper reviews the evidence for the use of ACPAs as a screening test in the broader general population, to identify individuals at high risk of subsequent onset of RA. We will review the diagnostic properties of the test and its positive and negative predictive value in different settings. We will discuss how ACPA testing could effectively be integrated in a broader screening strategy for RA.</p>
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   |flux=    an2020
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   |texte=   Measuring ACPA in the general population or primary care: is it useful?
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Measuring ACPA in the general population or primary care: is it useful?

Measuring ACPA in the general population or primary care: is it useful?

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