Treatment of sarcoidosis patients by steroid aerosol: a ten-year prospective study from Eastern India.
Identifieur interne : 000568 ( PubMed/Curation ); précédent : 000567; suivant : 000569Treatment of sarcoidosis patients by steroid aerosol: a ten-year prospective study from Eastern India.
Auteurs : S K Gupta [Inde]Source :
- Sarcoidosis [ 0393-1447 ] ; 1989.
Descripteurs français
- KwdFr :
- Administration par inhalation, Anti-inflammatoires non stéroïdiens (usage thérapeutique), Association de médicaments, Béclométasone (administration et posologie), Béclométasone (usage thérapeutique), Chloroquine (usage thérapeutique), Humains, Inde, Sarcoïdose (traitement médicamenteux), Études prospectives.
- MESH :
- administration et posologie : Béclométasone.
- traitement médicamenteux : Sarcoïdose.
- usage thérapeutique : Anti-inflammatoires non stéroïdiens, Béclométasone, Chloroquine.
- Administration par inhalation, Association de médicaments, Humains, Inde, Études prospectives.
- Wicri :
- geographic : Inde.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Beclomethasone.
- chemical , therapeutic use : Anti-Inflammatory Agents, Non-Steroidal, Beclomethasone, Chloroquine.
- geographic : India.
- drug therapy : Sarcoidosis.
- Administration, Inhalation, Drug Therapy, Combination, Humans, Prospective Studies.
Abstract
In a consecutive series of 113 cases of biopsy - proven sarcoidosis from Eastern India (1972-1986), steroid aerosols were used in 345 episodes, either alone or with one of the non-steroidal anti-inflammatory drugs (and added chloroquin) or with oral steroids. These, being analysed in detail, revealed satisfactory results only when used with other drugs. Used alone, its role is limited due to high cost, absence of systemic action unless used in high dosage, "hand to lung" delivery problem and difficulty of using in children. It is unsuitable in cases with life - threatening symptoms, neurological or cardiac problems. If used judiciously with suitable companion drugs, it can be used very effectively and can replace oral steroids in many patients.
PubMed: 2727421
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These, being analysed in detail, revealed satisfactory results only when used with other drugs. Used alone, its role is limited due to high cost, absence of systemic action unless used in high dosage, "hand to lung" delivery problem and difficulty of using in children. It is unsuitable in cases with life - threatening symptoms, neurological or cardiac problems. If used judiciously with suitable companion drugs, it can be used very effectively and can replace oral steroids in many patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2727421</PMID><DateCompleted><Year>1989</Year><Month>07</Month><Day>10</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0393-1447</ISSN><JournalIssue CitedMedium="Print"><Volume>6</Volume><Issue>1</Issue><PubDate><Year>1989</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Sarcoidosis</Title><ISOAbbreviation>Sarcoidosis</ISOAbbreviation></Journal><ArticleTitle>Treatment of sarcoidosis patients by steroid aerosol: a ten-year prospective study from Eastern India.</ArticleTitle><Pagination><MedlinePgn>51-4</MedlinePgn></Pagination><Abstract><AbstractText>In a consecutive series of 113 cases of biopsy - proven sarcoidosis from Eastern India (1972-1986), steroid aerosols were used in 345 episodes, either alone or with one of the non-steroidal anti-inflammatory drugs (and added chloroquin) or with oral steroids. These, being analysed in detail, revealed satisfactory results only when used with other drugs. Used alone, its role is limited due to high cost, absence of systemic action unless used in high dosage, "hand to lung" delivery problem and difficulty of using in children. It is unsuitable in cases with life - threatening symptoms, neurological or cardiac problems. If used judiciously with suitable companion drugs, it can be used very effectively and can replace oral steroids in many patients.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gupta</LastName><ForeName>S K</ForeName><Initials>SK</Initials><AffiliationInfo><Affiliation>Sarcoidosis Unit, Calcutta Medical Research Institute, India.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Italy</Country><MedlineTA>Sarcoidosis</MedlineTA><NlmUniqueID>8500778</NlmUniqueID><ISSNLinking>0393-1447</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000894">Anti-Inflammatory Agents, Non-Steroidal</NameOfSubstance></Chemical><Chemical><RegistryNumber>886U3H6UFF</RegistryNumber><NameOfSubstance UI="D002738">Chloroquine</NameOfSubstance></Chemical><Chemical><RegistryNumber>KGZ1SLC28Z</RegistryNumber><NameOfSubstance UI="D001507">Beclomethasone</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000280" MajorTopicYN="N">Administration, Inhalation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000894" MajorTopicYN="N">Anti-Inflammatory Agents, Non-Steroidal</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001507" MajorTopicYN="N">Beclomethasone</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002738" MajorTopicYN="N">Chloroquine</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004359" MajorTopicYN="N">Drug Therapy, Combination</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007194" MajorTopicYN="N" Type="Geographic">India</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012507" MajorTopicYN="N">Sarcoidosis</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1989</Year><Month>3</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1989</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1989</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2727421</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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