A rare comorbidity: neurosarcoidosis and cutaneous sarcoidosis.
Identifieur interne : 000228 ( PubMed/Curation ); précédent : 000227; suivant : 000229A rare comorbidity: neurosarcoidosis and cutaneous sarcoidosis.
Auteurs : Lütfi Akyol [Turquie] ; Kerim Aslan [Turquie] ; Metin Özgen [Turquie] ; Mehmet Sayarlioglu [Turquie]Source :
- BMJ case reports [ 1757-790X ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Bras, Comorbidité, Céphalée (étiologie), Dermatoses faciales (), Dermatoses faciales (traitement médicamenteux), Encéphalopathies (), Encéphalopathies (imagerie diagnostique), Encéphalopathies (traitement médicamenteux), Femelle, Humains, Maladie du système nerveux central (), Maladie du système nerveux central (traitement médicamenteux), Maladies de la peau (), Maladies de la peau (traitement médicamenteux), Radiographie, Sarcoïdose (), Sarcoïdose (traitement médicamenteux), Sarcoïdose pulmonaire (), Sarcoïdose pulmonaire (traitement médicamenteux), Syncope (étiologie).
- MESH :
- imagerie diagnostique : Encéphalopathies.
- traitement médicamenteux : Dermatoses faciales, Encéphalopathies, Maladie du système nerveux central, Maladies de la peau, Sarcoïdose, Sarcoïdose pulmonaire.
- étiologie : Céphalée, Syncope.
- Adulte d'âge moyen, Bras, Comorbidité, Dermatoses faciales, Encéphalopathies, Femelle, Humains, Maladie du système nerveux central, Maladies de la peau, Radiographie, Sarcoïdose, Sarcoïdose pulmonaire.
English descriptors
- KwdEn :
- Arm, Brain Diseases (complications), Brain Diseases (diagnostic imaging), Brain Diseases (drug therapy), Central Nervous System Diseases (complications), Central Nervous System Diseases (drug therapy), Comorbidity, Facial Dermatoses (complications), Facial Dermatoses (drug therapy), Female, Headache (etiology), Humans, Middle Aged, Radiography, Sarcoidosis (complications), Sarcoidosis (drug therapy), Sarcoidosis, Pulmonary (complications), Sarcoidosis, Pulmonary (drug therapy), Skin Diseases (complications), Skin Diseases (drug therapy), Syncope (etiology).
- MESH :
- complications : Brain Diseases, Central Nervous System Diseases, Facial Dermatoses, Sarcoidosis, Sarcoidosis, Pulmonary, Skin Diseases.
- diagnostic imaging : Brain Diseases.
- drug therapy : Brain Diseases, Central Nervous System Diseases, Facial Dermatoses, Sarcoidosis, Sarcoidosis, Pulmonary, Skin Diseases.
- etiology : Headache, Syncope.
- Arm, Comorbidity, Female, Humans, Middle Aged, Radiography.
Abstract
We present a case of a neurosarcoidosis patient with skin lesions. A 50-year-old woman was admitted with a 1-year history of violaceous, smooth and shiny plaques on her face and right arm. These lesions were biopsied and the histological examination indicated sarcoidosis. The patient had a history of headache and syncope that lasted for about 1 h. Brain CT showed masses measuring 37×20 mm in both frontal lobes. Thoracic and abdominal CT showed many pathologically enlarged lymph nodes. The patient was diagnosed with cutaneous, lung and neuronal sarcoidosis, and treated with 20 mg/day methylprednisolone, 15 mg/week methotrexate, 10 mg/week folic acid, 400 mg/day hydroxychloroquine and 800 mg/day carbamazepine. One month later, the patient's neurological symptoms had improved and her skin lesions had decreased. At 6-month follow-up, the size of the cranial masses had markedly regressed.
DOI: 10.1136/bcr-2015-211439
PubMed: 26578505
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A 50-year-old woman was admitted with a 1-year history of violaceous, smooth and shiny plaques on her face and right arm. These lesions were biopsied and the histological examination indicated sarcoidosis. The patient had a history of headache and syncope that lasted for about 1 h. Brain CT showed masses measuring 37×20 mm in both frontal lobes. Thoracic and abdominal CT showed many pathologically enlarged lymph nodes. The patient was diagnosed with cutaneous, lung and neuronal sarcoidosis, and treated with 20 mg/day methylprednisolone, 15 mg/week methotrexate, 10 mg/week folic acid, 400 mg/day hydroxychloroquine and 800 mg/day carbamazepine. One month later, the patient's neurological symptoms had improved and her skin lesions had decreased. At 6-month follow-up, the size of the cranial masses had markedly regressed. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26578505</PMID><DateCompleted><Year>2016</Year><Month>08</Month><Day>31</Day></DateCompleted><DateRevised><Year>2019</Year><Month>02</Month><Day>01</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1757-790X</ISSN><JournalIssue CitedMedium="Internet"><Volume>2015</Volume><PubDate><Year>2015</Year><Month>Nov</Month><Day>17</Day></PubDate></JournalIssue><Title>BMJ case reports</Title><ISOAbbreviation>BMJ Case Rep</ISOAbbreviation></Journal><ArticleTitle>A rare comorbidity: neurosarcoidosis and cutaneous sarcoidosis.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1136/bcr-2015-211439</ELocationID><ELocationID EIdType="pii" ValidYN="Y">bcr2015211439</ELocationID><Abstract><AbstractText>We present a case of a neurosarcoidosis patient with skin lesions. A 50-year-old woman was admitted with a 1-year history of violaceous, smooth and shiny plaques on her face and right arm. These lesions were biopsied and the histological examination indicated sarcoidosis. The patient had a history of headache and syncope that lasted for about 1 h. Brain CT showed masses measuring 37×20 mm in both frontal lobes. Thoracic and abdominal CT showed many pathologically enlarged lymph nodes. The patient was diagnosed with cutaneous, lung and neuronal sarcoidosis, and treated with 20 mg/day methylprednisolone, 15 mg/week methotrexate, 10 mg/week folic acid, 400 mg/day hydroxychloroquine and 800 mg/day carbamazepine. One month later, the patient's neurological symptoms had improved and her skin lesions had decreased. At 6-month follow-up, the size of the cranial masses had markedly regressed. </AbstractText><CopyrightInformation>2015 BMJ Publishing Group Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Akyol</LastName><ForeName>Lütfi</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Division of Rheumatology, Ondokuz Mayıs University Hospital, Samsun, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aslan</LastName><ForeName>Kerim</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Radiology, Ondokuz Mayıs University Hospital, Samsun, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Özgen</LastName><ForeName>Metin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Division of Rheumatology, Ondokuz Mayıs University Hospital, Samsun, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sayarlioglu</LastName><ForeName>Mehmet</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Division of Rheumatology, Ondokuz Mayıs University Hospital, Samsun, Turkey.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>11</Month><Day>17</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMJ Case Rep</MedlineTA><NlmUniqueID>101526291</NlmUniqueID><ISSNLinking>1757-790X</ISSNLinking></MedlineJournalInfo><SupplMeshList><SupplMeshName Type="Disease" UI="C535814">Neurosarcoidosis</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001132" 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