Interstitial lung disease in children--a report of four cases.
Identifieur interne : 000481 ( PubMed/Corpus ); précédent : 000480; suivant : 000482Interstitial lung disease in children--a report of four cases.
Auteurs : M Z Norzila ; B H Azizi ; C T Deng ; A. ZulfiqarSource :
- The Medical journal of Malaysia [ 0300-5283 ] ; 1997.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Lung Diseases, Interstitial.
- drug therapy : Lung Diseases, Interstitial.
- Female, Humans, Infant, Infant, Newborn, Male.
Abstract
Interstitial lung disease (ILD) is very rare in children. In the majority of cases the aetiology is unknown. Very little is known about the clinical course of this condition in children. Prognosis may be influenced by sex, age of onset of symptoms, radiographic features, presence of right ventricular hypertrophy and histopathology. We report our experience in managing four children with interstitial lung disease. All these children presented in early infancy with cough, respiratory distress, cyanosis and failure to thrive. Three of these children had finger clubbing and right ventricular hypertrophy. All patients received oral steroids. Chloroquine was added in two patients who showed no response. A trial of oral cyclophosphamide was started in one patient who failed with both drugs. One child is oxygen independent while another is on home oxygen therapy. The other two patients eventually died.
PubMed: 10968122
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Zulfiqar</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1997">1997</date><idno type="RBID">pubmed:10968122</idno><idno type="pmid">10968122</idno><idno type="wicri:Area/PubMed/Corpus">000481</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000481</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Interstitial lung disease in children--a report of four cases.</title><author><name sortKey="Norzila, M Z" sort="Norzila, M Z" uniqKey="Norzila M" first="M Z" last="Norzila">M Z Norzila</name><affiliation><nlm:affiliation>Institut Pediatrik, Hospital Kuala Lumpur.</nlm:affiliation></affiliation></author><author><name sortKey="Azizi, B H" sort="Azizi, B H" uniqKey="Azizi B" first="B H" last="Azizi">B H Azizi</name></author><author><name sortKey="Deng, C T" sort="Deng, C T" uniqKey="Deng C" first="C T" last="Deng">C T Deng</name></author><author><name sortKey="Zulfiqar, A" sort="Zulfiqar, A" uniqKey="Zulfiqar A" first="A" last="Zulfiqar">A. Zulfiqar</name></author></analytic><series><title level="j">The Medical journal of Malaysia</title><idno type="ISSN">0300-5283</idno><imprint><date when="1997" type="published">1997</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Female</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Lung Diseases, Interstitial (diagnosis)</term><term>Lung Diseases, Interstitial (drug therapy)</term><term>Male</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lung Diseases, Interstitial</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Lung Diseases, Interstitial</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Infant</term><term>Infant, Newborn</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Interstitial lung disease (ILD) is very rare in children. In the majority of cases the aetiology is unknown. Very little is known about the clinical course of this condition in children. Prognosis may be influenced by sex, age of onset of symptoms, radiographic features, presence of right ventricular hypertrophy and histopathology. We report our experience in managing four children with interstitial lung disease. All these children presented in early infancy with cough, respiratory distress, cyanosis and failure to thrive. Three of these children had finger clubbing and right ventricular hypertrophy. All patients received oral steroids. Chloroquine was added in two patients who showed no response. A trial of oral cyclophosphamide was started in one patient who failed with both drugs. One child is oxygen independent while another is on home oxygen therapy. The other two patients eventually died.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">10968122</PMID><DateCompleted><Year>2000</Year><Month>09</Month><Day>14</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0300-5283</ISSN><JournalIssue CitedMedium="Print"><Volume>52</Volume><Issue>4</Issue><PubDate><Year>1997</Year><Month>Dec</Month></PubDate></JournalIssue><Title>The Medical journal of Malaysia</Title><ISOAbbreviation>Med. J. Malaysia</ISOAbbreviation></Journal><ArticleTitle>Interstitial lung disease in children--a report of four cases.</ArticleTitle><Pagination><MedlinePgn>429-32</MedlinePgn></Pagination><Abstract><AbstractText>Interstitial lung disease (ILD) is very rare in children. In the majority of cases the aetiology is unknown. Very little is known about the clinical course of this condition in children. Prognosis may be influenced by sex, age of onset of symptoms, radiographic features, presence of right ventricular hypertrophy and histopathology. We report our experience in managing four children with interstitial lung disease. All these children presented in early infancy with cough, respiratory distress, cyanosis and failure to thrive. Three of these children had finger clubbing and right ventricular hypertrophy. All patients received oral steroids. Chloroquine was added in two patients who showed no response. A trial of oral cyclophosphamide was started in one patient who failed with both drugs. One child is oxygen independent while another is on home oxygen therapy. The other two patients eventually died.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Norzila</LastName><ForeName>M Z</ForeName><Initials>MZ</Initials><AffiliationInfo><Affiliation>Institut Pediatrik, Hospital Kuala Lumpur.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Azizi</LastName><ForeName>B H</ForeName><Initials>BH</Initials></Author><Author ValidYN="Y"><LastName>Deng</LastName><ForeName>C T</ForeName><Initials>CT</Initials></Author><Author ValidYN="Y"><LastName>Zulfiqar</LastName><ForeName>A</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Malaysia</Country><MedlineTA>Med J Malaysia</MedlineTA><NlmUniqueID>0361547</NlmUniqueID><ISSNLinking>0300-5283</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017563" MajorTopicYN="N">Lung Diseases, Interstitial</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2000</Year><Month>9</Month><Day>1</Day><Hour>11</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2000</Year><Month>9</Month><Day>19</Day><Hour>11</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2000</Year><Month>9</Month><Day>1</Day><Hour>11</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">10968122</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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