European protocols for the diagnosis and initial treatment of interstitial lung disease in children.
Identifieur interne : 000245 ( PubMed/Corpus ); précédent : 000244; suivant : 000246European protocols for the diagnosis and initial treatment of interstitial lung disease in children.
Auteurs : Andrew Bush ; Steve Cunningham ; Jacques De Blic ; Angelo Barbato ; Annick Clement ; Ralph Epaud ; Meike Hengst ; Nural Kiper ; Andrew G. Nicholson ; Martin Wetzke ; Deborah Snijders ; Nicolaus Schwerk ; Matthias GrieseSource :
- Thorax [ 1468-3296 ] ; 2015.
English descriptors
- KwdEn :
- Bronchoalveolar Lavage (methods), Bronchoscopy (methods), Child, Clinical Protocols, Diagnosis, Differential, Disease Management, Europe (epidemiology), Humans, Lung Diseases, Interstitial (diagnosis), Lung Diseases, Interstitial (epidemiology), Lung Diseases, Interstitial (therapy), Morbidity, Tomography, X-Ray Computed (methods).
- MESH :
- geographic , epidemiology : Europe.
- diagnosis : Lung Diseases, Interstitial.
- epidemiology : Lung Diseases, Interstitial.
- methods : Bronchoalveolar Lavage, Bronchoscopy, Tomography, X-Ray Computed.
- therapy : Lung Diseases, Interstitial.
- Child, Clinical Protocols, Diagnosis, Differential, Disease Management, Humans, Morbidity.
Abstract
Interstitial lung disease in children (chILD) is rare, and most centres will only see a few cases/year. There are numerous possible underlying diagnoses, with specific and non-specific treatment possibilities. The chILD-EU collaboration has brought together centres from across Europe to advance understanding of these considerations, and as part of this process, has created standard operating procedures and protocols for the investigation of chILD. Where established consensus documents exist already, for example, for the performance of bronchoalveolar lavage and processing of lung biopsies, these have been adopted. This manuscript reports our proposals for a staged investigation of chILD, starting from when the condition is suspected to defining the diagnosis, using pathways dependent on the clinical condition and the degree of illness of the child. These include the performance of genetic testing, echocardiography, high-resolution CT, bronchoscopy when appropriate and the definitive investigation of lung biopsy, in order to establish a precise diagnosis. Since no randomised controlled trials of treatment have ever been performed, we also report a Delphi consensus process to try to harmonise treatment protocols such as the use of intravenous and oral corticosteroids, and add-on therapies such as hydroxychloroquine and azithromycin. The aim is not to dictate to clinicians when a therapeutic trial should be performed, but to offer the possibility to collaborators of having a unified approach when a decision to treat has been made.
DOI: 10.1136/thoraxjnl-2015-207349
PubMed: 26135832
Links to Exploration step
pubmed:26135832Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">European protocols for the diagnosis and initial treatment of interstitial lung disease in children.</title><author><name sortKey="Bush, Andrew" sort="Bush, Andrew" uniqKey="Bush A" first="Andrew" last="Bush">Andrew Bush</name><affiliation><nlm:affiliation>Imperial College, National Heart and Lung Institute, Royal Brompton Harefield NHS Foundation Trust, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Cunningham, Steve" sort="Cunningham, Steve" uniqKey="Cunningham S" first="Steve" last="Cunningham">Steve Cunningham</name><affiliation><nlm:affiliation>NHS Lothian and University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="De Blic, Jacques" sort="De Blic, Jacques" uniqKey="De Blic J" first="Jacques" last="De Blic">Jacques De Blic</name><affiliation><nlm:affiliation>Pediatric Pulmonary Department, Hôpital Universitaire Necker Enfants Malades, Paris, France Université Paris Descartes, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Barbato, Angelo" sort="Barbato, Angelo" uniqKey="Barbato A" first="Angelo" last="Barbato">Angelo Barbato</name><affiliation><nlm:affiliation>Department of Women's and Children's Health, University of Padova, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Clement, Annick" sort="Clement, Annick" uniqKey="Clement A" first="Annick" last="Clement">Annick Clement</name><affiliation><nlm:affiliation>Hôpital Armand-Trousseau, Pneumologie pédiatrique, Centre National de Référence des Maladies Respiratoires Rares, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Epaud, Ralph" sort="Epaud, Ralph" uniqKey="Epaud R" first="Ralph" last="Epaud">Ralph Epaud</name><affiliation><nlm:affiliation>Faculté de Médecine, Centre Intercommunal de Créteil, Service de Pédiatrie, INSERM, U955, Université Paris-Est, Créteil, France.</nlm:affiliation></affiliation></author><author><name sortKey="Hengst, Meike" sort="Hengst, Meike" uniqKey="Hengst M" first="Meike" last="Hengst">Meike Hengst</name><affiliation><nlm:affiliation>Children's Hospital of Ludwig, Maximilians University, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kiper, Nural" sort="Kiper, Nural" uniqKey="Kiper N" first="Nural" last="Kiper">Nural Kiper</name><affiliation><nlm:affiliation>Faculty of Medicine, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.</nlm:affiliation></affiliation></author><author><name sortKey="Nicholson, Andrew G" sort="Nicholson, Andrew G" uniqKey="Nicholson A" first="Andrew G" last="Nicholson">Andrew G. Nicholson</name><affiliation><nlm:affiliation>Imperial College & Royal Brompton Harefield NHS Foundation Trust, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Wetzke, Martin" sort="Wetzke, Martin" uniqKey="Wetzke M" first="Martin" last="Wetzke">Martin Wetzke</name><affiliation><nlm:affiliation>Department of Pediatrics, Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Snijders, Deborah" sort="Snijders, Deborah" uniqKey="Snijders D" first="Deborah" last="Snijders">Deborah Snijders</name><affiliation><nlm:affiliation>Department of Women's and Children's Health, University of Padova, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Schwerk, Nicolaus" sort="Schwerk, Nicolaus" uniqKey="Schwerk N" first="Nicolaus" last="Schwerk">Nicolaus Schwerk</name><affiliation><nlm:affiliation>Department of Pediatric Pulmonology and Pediatric Lung Transplantation, Hannover Medical School, Clinic for Pediatric Pneumology, Allergology and Neonatology, Hannover, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Griese, Matthias" sort="Griese, Matthias" uniqKey="Griese M" first="Matthias" last="Griese">Matthias Griese</name><affiliation><nlm:affiliation>Lung Research Group, Children's Hospital of Ludwig, Maximilians University, Munich, Germany.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26135832</idno><idno type="pmid">26135832</idno><idno type="doi">10.1136/thoraxjnl-2015-207349</idno><idno type="wicri:Area/PubMed/Corpus">000245</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000245</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">European protocols for the diagnosis and initial treatment of interstitial lung disease in children.</title><author><name sortKey="Bush, Andrew" sort="Bush, Andrew" uniqKey="Bush A" first="Andrew" last="Bush">Andrew Bush</name><affiliation><nlm:affiliation>Imperial College, National Heart and Lung Institute, Royal Brompton Harefield NHS Foundation Trust, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Cunningham, Steve" sort="Cunningham, Steve" uniqKey="Cunningham S" first="Steve" last="Cunningham">Steve Cunningham</name><affiliation><nlm:affiliation>NHS Lothian and University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="De Blic, Jacques" sort="De Blic, Jacques" uniqKey="De Blic J" first="Jacques" last="De Blic">Jacques De Blic</name><affiliation><nlm:affiliation>Pediatric Pulmonary Department, Hôpital Universitaire Necker Enfants Malades, Paris, France Université Paris Descartes, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Barbato, Angelo" sort="Barbato, Angelo" uniqKey="Barbato A" first="Angelo" last="Barbato">Angelo Barbato</name><affiliation><nlm:affiliation>Department of Women's and Children's Health, University of Padova, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Clement, Annick" sort="Clement, Annick" uniqKey="Clement A" first="Annick" last="Clement">Annick Clement</name><affiliation><nlm:affiliation>Hôpital Armand-Trousseau, Pneumologie pédiatrique, Centre National de Référence des Maladies Respiratoires Rares, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Epaud, Ralph" sort="Epaud, Ralph" uniqKey="Epaud R" first="Ralph" last="Epaud">Ralph Epaud</name><affiliation><nlm:affiliation>Faculté de Médecine, Centre Intercommunal de Créteil, Service de Pédiatrie, INSERM, U955, Université Paris-Est, Créteil, France.</nlm:affiliation></affiliation></author><author><name sortKey="Hengst, Meike" sort="Hengst, Meike" uniqKey="Hengst M" first="Meike" last="Hengst">Meike Hengst</name><affiliation><nlm:affiliation>Children's Hospital of Ludwig, Maximilians University, Munich, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Kiper, Nural" sort="Kiper, Nural" uniqKey="Kiper N" first="Nural" last="Kiper">Nural Kiper</name><affiliation><nlm:affiliation>Faculty of Medicine, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.</nlm:affiliation></affiliation></author><author><name sortKey="Nicholson, Andrew G" sort="Nicholson, Andrew G" uniqKey="Nicholson A" first="Andrew G" last="Nicholson">Andrew G. Nicholson</name><affiliation><nlm:affiliation>Imperial College & Royal Brompton Harefield NHS Foundation Trust, London, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Wetzke, Martin" sort="Wetzke, Martin" uniqKey="Wetzke M" first="Martin" last="Wetzke">Martin Wetzke</name><affiliation><nlm:affiliation>Department of Pediatrics, Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Snijders, Deborah" sort="Snijders, Deborah" uniqKey="Snijders D" first="Deborah" last="Snijders">Deborah Snijders</name><affiliation><nlm:affiliation>Department of Women's and Children's Health, University of Padova, Padua, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Schwerk, Nicolaus" sort="Schwerk, Nicolaus" uniqKey="Schwerk N" first="Nicolaus" last="Schwerk">Nicolaus Schwerk</name><affiliation><nlm:affiliation>Department of Pediatric Pulmonology and Pediatric Lung Transplantation, Hannover Medical School, Clinic for Pediatric Pneumology, Allergology and Neonatology, Hannover, Germany.</nlm:affiliation></affiliation></author><author><name sortKey="Griese, Matthias" sort="Griese, Matthias" uniqKey="Griese M" first="Matthias" last="Griese">Matthias Griese</name><affiliation><nlm:affiliation>Lung Research Group, Children's Hospital of Ludwig, Maximilians University, Munich, Germany.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Thorax</title><idno type="eISSN">1468-3296</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bronchoalveolar Lavage (methods)</term><term>Bronchoscopy (methods)</term><term>Child</term><term>Clinical Protocols</term><term>Diagnosis, Differential</term><term>Disease Management</term><term>Europe (epidemiology)</term><term>Humans</term><term>Lung Diseases, Interstitial (diagnosis)</term><term>Lung Diseases, Interstitial (epidemiology)</term><term>Lung Diseases, Interstitial (therapy)</term><term>Morbidity</term><term>Tomography, X-Ray Computed (methods)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Europe</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lung Diseases, Interstitial</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Lung Diseases, Interstitial</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Bronchoalveolar Lavage</term><term>Bronchoscopy</term><term>Tomography, X-Ray Computed</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lung Diseases, Interstitial</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child</term><term>Clinical Protocols</term><term>Diagnosis, Differential</term><term>Disease Management</term><term>Humans</term><term>Morbidity</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Interstitial lung disease in children (chILD) is rare, and most centres will only see a few cases/year. There are numerous possible underlying diagnoses, with specific and non-specific treatment possibilities. The chILD-EU collaboration has brought together centres from across Europe to advance understanding of these considerations, and as part of this process, has created standard operating procedures and protocols for the investigation of chILD. Where established consensus documents exist already, for example, for the performance of bronchoalveolar lavage and processing of lung biopsies, these have been adopted. This manuscript reports our proposals for a staged investigation of chILD, starting from when the condition is suspected to defining the diagnosis, using pathways dependent on the clinical condition and the degree of illness of the child. These include the performance of genetic testing, echocardiography, high-resolution CT, bronchoscopy when appropriate and the definitive investigation of lung biopsy, in order to establish a precise diagnosis. Since no randomised controlled trials of treatment have ever been performed, we also report a Delphi consensus process to try to harmonise treatment protocols such as the use of intravenous and oral corticosteroids, and add-on therapies such as hydroxychloroquine and azithromycin. The aim is not to dictate to clinicians when a therapeutic trial should be performed, but to offer the possibility to collaborators of having a unified approach when a decision to treat has been made. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26135832</PMID><DateCompleted><Year>2016</Year><Month>01</Month><Day>19</Day></DateCompleted><DateRevised><Year>2015</Year><Month>10</Month><Day>15</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1468-3296</ISSN><JournalIssue CitedMedium="Internet"><Volume>70</Volume><Issue>11</Issue><PubDate><Year>2015</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Thorax</Title><ISOAbbreviation>Thorax</ISOAbbreviation></Journal><ArticleTitle>European protocols for the diagnosis and initial treatment of interstitial lung disease in children.</ArticleTitle><Pagination><MedlinePgn>1078-84</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1136/thoraxjnl-2015-207349</ELocationID><Abstract><AbstractText>Interstitial lung disease in children (chILD) is rare, and most centres will only see a few cases/year. There are numerous possible underlying diagnoses, with specific and non-specific treatment possibilities. The chILD-EU collaboration has brought together centres from across Europe to advance understanding of these considerations, and as part of this process, has created standard operating procedures and protocols for the investigation of chILD. Where established consensus documents exist already, for example, for the performance of bronchoalveolar lavage and processing of lung biopsies, these have been adopted. This manuscript reports our proposals for a staged investigation of chILD, starting from when the condition is suspected to defining the diagnosis, using pathways dependent on the clinical condition and the degree of illness of the child. These include the performance of genetic testing, echocardiography, high-resolution CT, bronchoscopy when appropriate and the definitive investigation of lung biopsy, in order to establish a precise diagnosis. Since no randomised controlled trials of treatment have ever been performed, we also report a Delphi consensus process to try to harmonise treatment protocols such as the use of intravenous and oral corticosteroids, and add-on therapies such as hydroxychloroquine and azithromycin. The aim is not to dictate to clinicians when a therapeutic trial should be performed, but to offer the possibility to collaborators of having a unified approach when a decision to treat has been made. </AbstractText><CopyrightInformation>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bush</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Imperial College, National Heart and Lung Institute, Royal Brompton Harefield NHS Foundation Trust, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cunningham</LastName><ForeName>Steve</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>NHS Lothian and University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Blic</LastName><ForeName>Jacques</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Pediatric Pulmonary Department, Hôpital Universitaire Necker Enfants Malades, Paris, France Université Paris Descartes, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barbato</LastName><ForeName>Angelo</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Women's and Children's Health, University of Padova, Padua, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Clement</LastName><ForeName>Annick</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Hôpital Armand-Trousseau, Pneumologie pédiatrique, Centre National de Référence des Maladies Respiratoires Rares, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Epaud</LastName><ForeName>Ralph</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Faculté de Médecine, Centre Intercommunal de Créteil, Service de Pédiatrie, INSERM, U955, Université Paris-Est, Créteil, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hengst</LastName><ForeName>Meike</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Children's Hospital of Ludwig, Maximilians University, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kiper</LastName><ForeName>Nural</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Faculty of Medicine, Department of Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nicholson</LastName><ForeName>Andrew G</ForeName><Initials>AG</Initials><AffiliationInfo><Affiliation>Imperial College & Royal Brompton Harefield NHS Foundation Trust, London, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wetzke</LastName><ForeName>Martin</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Pediatrics, Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Snijders</LastName><ForeName>Deborah</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Women's and Children's Health, University of Padova, Padua, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schwerk</LastName><ForeName>Nicolaus</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Department of Pediatric Pulmonology and Pediatric Lung Transplantation, Hannover Medical School, Clinic for Pediatric Pneumology, Allergology and Neonatology, Hannover, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Griese</LastName><ForeName>Matthias</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Lung Research Group, Children's Hospital of Ludwig, Maximilians University, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>chILD-EU Collaboration</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>07</Month><Day>01</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Thorax</MedlineTA><NlmUniqueID>0417353</NlmUniqueID><ISSNLinking>0040-6376</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D018893" MajorTopicYN="N">Bronchoalveolar Lavage</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001999" MajorTopicYN="N">Bronchoscopy</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002985" MajorTopicYN="Y">Clinical Protocols</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019468" MajorTopicYN="Y">Disease Management</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005060" MajorTopicYN="N" Type="Geographic">Europe</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017563" MajorTopicYN="Y">Lung Diseases, Interstitial</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009017" MajorTopicYN="N">Morbidity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014057" MajorTopicYN="N">Tomography, X-Ray Computed</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">ABCA3</Keyword><Keyword MajorTopicYN="N">GM-CSF Receptor</Keyword><Keyword MajorTopicYN="N">Hypersensitivity pneumonitis</Keyword><Keyword MajorTopicYN="N">Idiopathic pulmonary fibrosis</Keyword><Keyword MajorTopicYN="N">NEHI</Keyword><Keyword MajorTopicYN="N">PIG</Keyword><Keyword MajorTopicYN="N">Surfactant protein</Keyword><Keyword MajorTopicYN="N">TTF-1</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>06</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>06</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>7</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>7</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>1</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26135832</ArticleId><ArticleId IdType="pii">thoraxjnl-2015-207349</ArticleId><ArticleId IdType="doi">10.1136/thoraxjnl-2015-207349</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000245 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000245 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:26135832
|texte= European protocols for the diagnosis and initial treatment of interstitial lung disease in children.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:26135832" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a ChloroquineV1
| This area was generated with Dilib version V0.6.33. |  |