Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review.
Identifieur interne : 000235 ( PubMed/Corpus ); précédent : 000234; suivant : 000236Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review.
Auteurs : M F Polo ; S. Mastrandrea ; L. Santoru ; A. Arcadu ; G. Masala ; V. Marras ; G. Bagella ; M M Sechi ; F. Tanda ; P. PirinaSource :
- Microbes and infection [ 1769-714X ]
English descriptors
- KwdEn :
- Anti-Bacterial Agents (therapeutic use), Antibodies, Bacterial (blood), Antibodies, Bacterial (immunology), Coxiella burnetii (immunology), Coxiella burnetii (pathogenicity), Doxycycline (therapeutic use), Humans, Hydroxychloroquine (therapeutic use), Male, Middle Aged, Plasma Cell Granuloma, Pulmonary (diagnostic imaging), Plasma Cell Granuloma, Pulmonary (drug therapy), Plasma Cell Granuloma, Pulmonary (microbiology), Q Fever (drug therapy), Q Fever (microbiology), Radiography.
- MESH :
- chemical , blood : Antibodies, Bacterial.
- chemical , immunology : Antibodies, Bacterial.
- chemical , therapeutic use : Anti-Bacterial Agents, Doxycycline, Hydroxychloroquine.
- diagnostic imaging : Plasma Cell Granuloma, Pulmonary.
- drug therapy : Plasma Cell Granuloma, Pulmonary, Q Fever.
- immunology : Coxiella burnetii.
- microbiology : Plasma Cell Granuloma, Pulmonary, Q Fever.
- pathogenicity : Coxiella burnetii.
- Humans, Male, Middle Aged, Radiography.
Abstract
A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever.
DOI: 10.1016/j.micinf.2015.08.008
PubMed: 26342254
Links to Exploration step
pubmed:26342254Le document en format XML
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Santoru</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Arcadu, A" sort="Arcadu, A" uniqKey="Arcadu A" first="A" last="Arcadu">A. Arcadu</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Masala, G" sort="Masala, G" uniqKey="Masala G" first="G" last="Masala">G. Masala</name><affiliation><nlm:affiliation>Experimental Zooprophylactic Institute of Sardinia, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Marras, V" sort="Marras, V" uniqKey="Marras V" first="V" last="Marras">V. Marras</name><affiliation><nlm:affiliation>Department of Biomedical Sciences, Institute of Pathology, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Bagella, G" sort="Bagella, G" uniqKey="Bagella G" first="G" last="Bagella">G. Bagella</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Sechi, M M" sort="Sechi, M M" uniqKey="Sechi M" first="M M" last="Sechi">M M Sechi</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tanda, F" sort="Tanda, F" uniqKey="Tanda F" first="F" last="Tanda">F. 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Case report and literature review.</title><author><name sortKey="Polo, M F" sort="Polo, M F" uniqKey="Polo M" first="M F" last="Polo">M F Polo</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy. Electronic address: pmaria_francesca@hotmail.com.</nlm:affiliation></affiliation></author><author><name sortKey="Mastrandrea, S" sort="Mastrandrea, S" uniqKey="Mastrandrea S" first="S" last="Mastrandrea">S. Mastrandrea</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Santoru, L" sort="Santoru, L" uniqKey="Santoru L" first="L" last="Santoru">L. Santoru</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Arcadu, A" sort="Arcadu, A" uniqKey="Arcadu A" first="A" last="Arcadu">A. Arcadu</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Masala, G" sort="Masala, G" uniqKey="Masala G" first="G" last="Masala">G. Masala</name><affiliation><nlm:affiliation>Experimental Zooprophylactic Institute of Sardinia, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Marras, V" sort="Marras, V" uniqKey="Marras V" first="V" last="Marras">V. Marras</name><affiliation><nlm:affiliation>Department of Biomedical Sciences, Institute of Pathology, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Bagella, G" sort="Bagella, G" uniqKey="Bagella G" first="G" last="Bagella">G. Bagella</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Sechi, M M" sort="Sechi, M M" uniqKey="Sechi M" first="M M" last="Sechi">M M Sechi</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Tanda, F" sort="Tanda, F" uniqKey="Tanda F" first="F" last="Tanda">F. Tanda</name><affiliation><nlm:affiliation>Department of Biomedical Sciences, Institute of Pathology, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author><author><name sortKey="Pirina, P" sort="Pirina, P" uniqKey="Pirina P" first="P" last="Pirina">P. Pirina</name><affiliation><nlm:affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Microbes and infection</title><idno type="eISSN">1769-714X</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Bacterial Agents (therapeutic use)</term><term>Antibodies, Bacterial (blood)</term><term>Antibodies, Bacterial (immunology)</term><term>Coxiella burnetii (immunology)</term><term>Coxiella burnetii (pathogenicity)</term><term>Doxycycline (therapeutic use)</term><term>Humans</term><term>Hydroxychloroquine (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Plasma Cell Granuloma, Pulmonary (diagnostic imaging)</term><term>Plasma Cell Granuloma, Pulmonary (drug therapy)</term><term>Plasma Cell Granuloma, Pulmonary (microbiology)</term><term>Q Fever (drug therapy)</term><term>Q Fever (microbiology)</term><term>Radiography</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Bacterial</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Bacterial</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Doxycycline</term><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Plasma Cell Granuloma, Pulmonary</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Plasma Cell Granuloma, Pulmonary</term><term>Q Fever</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coxiella burnetii</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Plasma Cell Granuloma, Pulmonary</term><term>Q Fever</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Coxiella burnetii</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Radiography</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26342254</PMID><DateCompleted><Year>2016</Year><Month>10</Month><Day>05</Day></DateCompleted><DateRevised><Year>2017</Year><Month>01</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1769-714X</ISSN><JournalIssue CitedMedium="Internet"><Volume>17</Volume><Issue>11-12</Issue><PubDate><MedlineDate>2015 Nov-Dec</MedlineDate></PubDate></JournalIssue><Title>Microbes and infection</Title><ISOAbbreviation>Microbes Infect.</ISOAbbreviation></Journal><ArticleTitle>Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review.</ArticleTitle><Pagination><MedlinePgn>795-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.micinf.2015.08.008</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1286-4579(15)00168-9</ELocationID><Abstract><AbstractText>A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever. </AbstractText><CopyrightInformation>Copyright © 2015. Published by Elsevier Masson SAS.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Polo</LastName><ForeName>M F</ForeName><Initials>MF</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy. Electronic address: pmaria_francesca@hotmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mastrandrea</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Santoru</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arcadu</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Masala</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Experimental Zooprophylactic Institute of Sardinia, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Marras</LastName><ForeName>V</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Biomedical Sciences, Institute of Pathology, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bagella</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sechi</LastName><ForeName>M M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tanda</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Department of Biomedical Sciences, Institute of Pathology, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pirina</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>09</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Microbes Infect</MedlineTA><NlmUniqueID>100883508</NlmUniqueID><ISSNLinking>1286-4579</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000907">Antibodies, Bacterial</NameOfSubstance></Chemical><Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber><NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance></Chemical><Chemical><RegistryNumber>N12000U13O</RegistryNumber><NameOfSubstance UI="D004318">Doxycycline</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000907" MajorTopicYN="N">Antibodies, Bacterial</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016997" MajorTopicYN="N">Coxiella burnetii</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004318" MajorTopicYN="N">Doxycycline</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016726" MajorTopicYN="Y">Plasma Cell Granuloma, Pulmonary</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011778" MajorTopicYN="N">Q Fever</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011859" MajorTopicYN="N">Radiography</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Coxiella burnetii</Keyword><Keyword MajorTopicYN="N">Infection</Keyword><Keyword MajorTopicYN="N">Pulmonary pseudotumor</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>06</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2015</Year><Month>08</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>08</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>9</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>9</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>10</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26342254</ArticleId><ArticleId IdType="pii">S1286-4579(15)00168-9</ArticleId><ArticleId IdType="doi">10.1016/j.micinf.2015.08.008</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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