Dramatic response of refractory sarcoidosis under ruxolitinib in a patient with associated JAK2-mutated polycythemia.
Identifieur interne : 000078 ( PubMed/Corpus ); précédent : 000077; suivant : 000079Dramatic response of refractory sarcoidosis under ruxolitinib in a patient with associated JAK2-mutated polycythemia.
Auteurs : Cécile Rotenberg ; Valérie Besnard ; Pierre-Yves Brillet ; Stéphane Giraudier ; Hilario Nunes ; Dominique ValeyreSource :
- The European respiratory journal [ 1399-3003 ] ; 2018.
English descriptors
- KwdEn :
- Adrenal Cortex Hormones (therapeutic use), Biopsy, Female, Humans, Hydroxychloroquine (therapeutic use), Janus Kinase 2 (genetics), Middle Aged, Mutation, Polycythemia Vera (drug therapy), Polycythemia Vera (genetics), Pyrazoles (therapeutic use), Radiography, Thoracic, Sarcoidosis (drug therapy), Sarcoidosis (genetics), Signal Transduction, Tomography, X-Ray Computed, Treatment Outcome.
- MESH :
- chemical , genetics : Janus Kinase 2.
- chemical , therapeutic use : Adrenal Cortex Hormones, Hydroxychloroquine, Pyrazoles.
- drug therapy : Polycythemia Vera, Sarcoidosis.
- genetics : Polycythemia Vera, Sarcoidosis.
- Biopsy, Female, Humans, Middle Aged, Mutation, Radiography, Thoracic, Signal Transduction, Tomography, X-Ray Computed, Treatment Outcome.
DOI: 10.1183/13993003.01482-2018
PubMed: 30361243
Links to Exploration step
pubmed:30361243Le document en format XML
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Brillet</name><affiliation><nlm:affiliation>Dept of Radiology, APHP, Avicenne Hospital, Bobigny, France.</nlm:affiliation></affiliation></author><author><name sortKey="Giraudier, Stephane" sort="Giraudier, Stephane" uniqKey="Giraudier S" first="Stéphane" last="Giraudier">Stéphane Giraudier</name><affiliation><nlm:affiliation>Dept of Cellular Biology, INSERM U1131, APHP, Saint Louis Hospital, Paris-Diderot University, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Nunes, Hilario" sort="Nunes, Hilario" uniqKey="Nunes H" first="Hilario" last="Nunes">Hilario Nunes</name><affiliation><nlm:affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</nlm:affiliation></affiliation></author><author><name sortKey="Valeyre, Dominique" sort="Valeyre, Dominique" uniqKey="Valeyre D" first="Dominique" last="Valeyre">Dominique Valeyre</name><affiliation><nlm:affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:30361243</idno><idno type="pmid">30361243</idno><idno type="doi">10.1183/13993003.01482-2018</idno><idno type="wicri:Area/PubMed/Corpus">000078</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000078</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Dramatic response of refractory sarcoidosis under ruxolitinib in a patient with associated JAK2-mutated polycythemia.</title><author><name sortKey="Rotenberg, Cecile" sort="Rotenberg, Cecile" uniqKey="Rotenberg C" first="Cécile" last="Rotenberg">Cécile Rotenberg</name><affiliation><nlm:affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</nlm:affiliation></affiliation></author><author><name sortKey="Besnard, Valerie" sort="Besnard, Valerie" uniqKey="Besnard V" first="Valérie" last="Besnard">Valérie Besnard</name><affiliation><nlm:affiliation>EA 2363 "Hypoxia & the lung: fibrosing pneumonitis, ventilatory and circulatory modulations", UFR SMBH, Université Paris 13, Sorbonne Paris Cite, Bobigny, France.</nlm:affiliation></affiliation></author><author><name sortKey="Brillet, Pierre Yves" sort="Brillet, Pierre Yves" uniqKey="Brillet P" first="Pierre-Yves" last="Brillet">Pierre-Yves Brillet</name><affiliation><nlm:affiliation>Dept of Radiology, APHP, Avicenne Hospital, Bobigny, France.</nlm:affiliation></affiliation></author><author><name sortKey="Giraudier, Stephane" sort="Giraudier, Stephane" uniqKey="Giraudier S" first="Stéphane" last="Giraudier">Stéphane Giraudier</name><affiliation><nlm:affiliation>Dept of Cellular Biology, INSERM U1131, APHP, Saint Louis Hospital, Paris-Diderot University, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Nunes, Hilario" sort="Nunes, Hilario" uniqKey="Nunes H" first="Hilario" last="Nunes">Hilario Nunes</name><affiliation><nlm:affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</nlm:affiliation></affiliation></author><author><name sortKey="Valeyre, Dominique" sort="Valeyre, Dominique" uniqKey="Valeyre D" first="Dominique" last="Valeyre">Dominique Valeyre</name><affiliation><nlm:affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</nlm:affiliation></affiliation></author></analytic><series><title level="j">The European respiratory journal</title><idno type="eISSN">1399-3003</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adrenal Cortex Hormones (therapeutic use)</term><term>Biopsy</term><term>Female</term><term>Humans</term><term>Hydroxychloroquine (therapeutic use)</term><term>Janus Kinase 2 (genetics)</term><term>Middle Aged</term><term>Mutation</term><term>Polycythemia Vera (drug therapy)</term><term>Polycythemia Vera (genetics)</term><term>Pyrazoles (therapeutic use)</term><term>Radiography, Thoracic</term><term>Sarcoidosis (drug therapy)</term><term>Sarcoidosis (genetics)</term><term>Signal Transduction</term><term>Tomography, X-Ray Computed</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Janus Kinase 2</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Adrenal Cortex Hormones</term><term>Hydroxychloroquine</term><term>Pyrazoles</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Polycythemia Vera</term><term>Sarcoidosis</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Polycythemia Vera</term><term>Sarcoidosis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biopsy</term><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Mutation</term><term>Radiography, Thoracic</term><term>Signal Transduction</term><term>Tomography, X-Ray Computed</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30361243</PMID><DateCompleted><Year>2019</Year><Month>10</Month><Day>29</Day></DateCompleted><DateRevised><Year>2019</Year><Month>10</Month><Day>29</Day></DateRevised><Article PubModel="Electronic-Print"><Journal><ISSN IssnType="Electronic">1399-3003</ISSN><JournalIssue CitedMedium="Internet"><Volume>52</Volume><Issue>6</Issue><PubDate><Year>2018</Year><Month>12</Month></PubDate></JournalIssue><Title>The European respiratory journal</Title><ISOAbbreviation>Eur. Respir. J.</ISOAbbreviation></Journal><ArticleTitle>Dramatic response of refractory sarcoidosis under ruxolitinib in a patient with associated JAK2-mutated polycythemia.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">1801482</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1183/13993003.01482-2018</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Rotenberg</LastName><ForeName>Cécile</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>These authors contributed equally.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Besnard</LastName><ForeName>Valérie</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>EA 2363 "Hypoxia & the lung: fibrosing pneumonitis, ventilatory and circulatory modulations", UFR SMBH, Université Paris 13, Sorbonne Paris Cite, Bobigny, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>These authors contributed equally.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brillet</LastName><ForeName>Pierre-Yves</ForeName><Initials>PY</Initials><AffiliationInfo><Affiliation>Dept of Radiology, APHP, Avicenne Hospital, Bobigny, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Giraudier</LastName><ForeName>Stéphane</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Dept of Cellular Biology, INSERM U1131, APHP, Saint Louis Hospital, Paris-Diderot University, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nunes</LastName><ForeName>Hilario</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>EA 2363 "Hypoxia & the lung: fibrosing pneumonitis, ventilatory and circulatory modulations", UFR SMBH, Université Paris 13, Sorbonne Paris Cite, Bobigny, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Valeyre</LastName><ForeName>Dominique</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Dept of Respiratory Diseases, APHP, Avicenne Hospital, Bobigny, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>EA 2363 "Hypoxia & the lung: fibrosing pneumonitis, ventilatory and circulatory modulations", UFR SMBH, Université Paris 13, Sorbonne Paris Cite, Bobigny, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016422">Letter</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>12</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur Respir J</MedlineTA><NlmUniqueID>8803460</NlmUniqueID><ISSNLinking>0903-1936</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000305">Adrenal Cortex Hormones</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C540383">INCB018424</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011720">Pyrazoles</NameOfSubstance></Chemical><Chemical><RegistryNumber>4QWG6N8QKH</RegistryNumber><NameOfSubstance UI="D006886">Hydroxychloroquine</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.7.10.2</RegistryNumber><NameOfSubstance UI="C507924">JAK2 protein, human</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.7.10.2</RegistryNumber><NameOfSubstance UI="D053614">Janus Kinase 2</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000305" MajorTopicYN="N">Adrenal Cortex Hormones</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001706" MajorTopicYN="N">Biopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006886" MajorTopicYN="N">Hydroxychloroquine</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053614" MajorTopicYN="N">Janus Kinase 2</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009154" MajorTopicYN="N">Mutation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011087" MajorTopicYN="N">Polycythemia Vera</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011720" MajorTopicYN="N">Pyrazoles</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013902" MajorTopicYN="N">Radiography, Thoracic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012507" MajorTopicYN="N">Sarcoidosis</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015398" MajorTopicYN="N">Signal Transduction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014057" MajorTopicYN="N">Tomography, X-Ray Computed</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><CoiStatement>Conflict of interest: C. Rotenberg has nothing to disclose. Conflict of interest: V. Besnard has nothing to disclose. Conflict of interest: P-Y. Brillet has nothing to disclose. Conflict of interest: S. Giraudier reports grants from Novartis. Conflict of interest: H. Nunes reports grants and personal fees for consultancy and research from Roche/Genentech and Boehringer Ingelheim, other (for investigator in clinical trials) from Sanofi and Gilead, outside the submitted work. Conflict of interest: D. Valeyre reports personal fees (scientific advisory board membership) from Boehringer Ingelheim and Roche, personal fees for lecturing from AstraZeneca, and personal fees for travel and accommodation from Boehringer Ingelheim and Roche, outside the submitted work.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>08</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>09</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>10</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>10</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>10</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30361243</ArticleId><ArticleId IdType="pii">13993003.01482-2018</ArticleId><ArticleId IdType="doi">10.1183/13993003.01482-2018</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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