Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry.
Identifieur interne : 000050 ( PubMed/Checkpoint ); précédent : 000049; suivant : 000051Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry.
Auteurs : Natalia Mena-Vázquez ; Antonio Fernández-Nebro ; José María Pego-Reigosa ; María Galindo [Espagne] ; Ana Melissa-Anzola [Espagne] ; Esther Uriarte-Isacelay ; Alejandro Olivé-Marqués ; Elena Aurrecoechea ; Mercedes Freire ; Eva Tomero [Espagne] ; María Jesús García-Villanueva [Espagne] ; Claudia Stoye ; Esteban Salas-Heredia ; Jose Antonio Bernal-Vidal ; Eva Salgado ; Ricardo Blanco ; Francisco Javier Novoa ; M Nica Ibá Ez-Barcelo ; Vicente Torrente-Segarra [Espagne] ; Javier Narvaez [Espagne] ; Joan Calvet ; Clara Moriano Morales ; Tomas Ramon Vazquez-Rodriguez ; Paloma Garcia De La Pe A [Espagne] ; Cristina Boh Rquez [Espagne] ; José Luis Andreu-Sánchez [Espagne] ; Tatiana Cobo-Iba Ez [Espagne] ; Gema Bonilla [Espagne] ; Nuria Lozano-Rivas ; Carlos Montilla ; Francisco Javier Toyos ; Jose Luis Marenco De La Fuente ; Lorena Exp Sito ; María Esther Ruiz-Lucea ; Elia Vals ; Javier Manero-Ruiz ; Jose A. Bernal-Vidal ; I Igo Rua-Figueroa [Espagne]Source :
- Rheumatology (Oxford, England) [ 1462-0332 ] ; 2019.
Abstract
This article estimates the frequency of polyautoimmunity and associated factors in a large retrospective cohort of patients with SLE.
DOI: 10.1093/rheumatology/kez562
PubMed: 31808534
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry.</title>
<author><name sortKey="Mena Vazquez, Natalia" sort="Mena Vazquez, Natalia" uniqKey="Mena Vazquez N" first="Natalia" last="Mena-Vázquez">Natalia Mena-Vázquez</name>
<affiliation><nlm:affiliation>Instituto de Investigación Biomédica de Málaga - IBIMA, Malaga.</nlm:affiliation>
<wicri:noCountry code="subField">Malaga</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fernandez Nebro, Antonio" sort="Fernandez Nebro, Antonio" uniqKey="Fernandez Nebro A" first="Antonio" last="Fernández-Nebro">Antonio Fernández-Nebro</name>
<affiliation><nlm:affiliation>Instituto de Investigación Biomédica de Málaga - IBIMA, Malaga.</nlm:affiliation>
<wicri:noCountry code="subField">Malaga</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pego Reigosa, Jose Maria" sort="Pego Reigosa, Jose Maria" uniqKey="Pego Reigosa J" first="José María" last="Pego-Reigosa">José María Pego-Reigosa</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital do Meixoeiro, Vigo, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Galindo, Maria" sort="Galindo, Maria" uniqKey="Galindo M" first="María" last="Galindo">María Galindo</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario 12 de Octubre, Madrid.</nlm:affiliation>
<country>Espagne</country>
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</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario 12 de Octubre</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Melissa Anzola, Ana" sort="Melissa Anzola, Ana" uniqKey="Melissa Anzola A" first="Ana" last="Melissa-Anzola">Ana Melissa-Anzola</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid.</nlm:affiliation>
<country>Espagne</country>
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<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital General Universitario Gregorio Marañón</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Uriarte Isacelay, Esther" sort="Uriarte Isacelay, Esther" uniqKey="Uriarte Isacelay E" first="Esther" last="Uriarte-Isacelay">Esther Uriarte-Isacelay</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Donostia, San Sebastian, País Vasco.</nlm:affiliation>
<wicri:noCountry code="subField">País Vasco</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Olive Marques, Alejandro" sort="Olive Marques, Alejandro" uniqKey="Olive Marques A" first="Alejandro" last="Olivé-Marqués">Alejandro Olivé-Marqués</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Catalunya.</nlm:affiliation>
<wicri:noCountry code="subField">Catalunya</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Aurrecoechea, Elena" sort="Aurrecoechea, Elena" uniqKey="Aurrecoechea E" first="Elena" last="Aurrecoechea">Elena Aurrecoechea</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Sierrallana, Torrelavega, Cantabria.</nlm:affiliation>
<wicri:noCountry code="subField">Cantabria</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Freire, Mercedes" sort="Freire, Mercedes" uniqKey="Freire M" first="Mercedes" last="Freire">Mercedes Freire</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Juan Canalejo de La Coruña, A Coruna, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tomero, Eva" sort="Tomero, Eva" uniqKey="Tomero E" first="Eva" last="Tomero">Eva Tomero</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de la Princesa, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario de la Princesa</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Garcia Villanueva, Maria Jesus" sort="Garcia Villanueva, Maria Jesus" uniqKey="Garcia Villanueva M" first="María Jesús" last="García-Villanueva">María Jesús García-Villanueva</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Ramon y Cajal, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Ramon y Cajal</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Stoye, Claudia" sort="Stoye, Claudia" uniqKey="Stoye C" first="Claudia" last="Stoye">Claudia Stoye</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital de Navarra, Pamplona, Navarra.</nlm:affiliation>
<wicri:noCountry code="subField">Navarra</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Salas Heredia, Esteban" sort="Salas Heredia, Esteban" uniqKey="Salas Heredia E" first="Esteban" last="Salas-Heredia">Esteban Salas-Heredia</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Marina Baixa, Villajoyosa, Valencia.</nlm:affiliation>
<wicri:noCountry code="subField">Valencia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bernal Vidal, Jose Antonio" sort="Bernal Vidal, Jose Antonio" uniqKey="Bernal Vidal J" first="Jose Antonio" last="Bernal-Vidal">Jose Antonio Bernal-Vidal</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital General Universitario de Alicante, Alicante, Valencia.</nlm:affiliation>
<wicri:noCountry code="subField">Valencia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Salgado, Eva" sort="Salgado, Eva" uniqKey="Salgado E" first="Eva" last="Salgado">Eva Salgado</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Complejo Hospitalario de Orense, Ourense, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Blanco, Ricardo" sort="Blanco, Ricardo" uniqKey="Blanco R" first="Ricardo" last="Blanco">Ricardo Blanco</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Marques de Valdecilla, Santander, Cantabria.</nlm:affiliation>
<wicri:noCountry code="subField">Cantabria</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Javier Novoa, Francisco" sort="Javier Novoa, Francisco" uniqKey="Javier Novoa F" first="Francisco" last="Javier Novoa">Francisco Javier Novoa</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria.</nlm:affiliation>
<wicri:noCountry code="subField">Las Palmas de Gran Canaria</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Iba Ez Barcelo, M Nica" sort="Iba Ez Barcelo, M Nica" uniqKey="Iba Ez Barcelo M" first="M Nica" last="Ibá Ez-Barcelo">M Nica Ibá Ez-Barcelo</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Son Llatzer, Palma de Mallorca, Illes Balears.</nlm:affiliation>
<wicri:noCountry code="subField">Illes Balears</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Torrente Segarra, Vicente" sort="Torrente Segarra, Vicente" uniqKey="Torrente Segarra V" first="Vicente" last="Torrente-Segarra">Vicente Torrente-Segarra</name>
<affiliation wicri:level="3"><nlm:affiliation>Rheumatology Vilafranca del Penedes, Hospital Comarcal de l'Alt Penedes, Barcelona.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
<wicri:orgArea>Rheumatology Vilafranca del Penedes, Hospital Comarcal de l'Alt Penedes</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Narvaez, Javier" sort="Narvaez, Javier" uniqKey="Narvaez J" first="Javier" last="Narvaez">Javier Narvaez</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology L'Hospitalet de Llobregat, Hospital Universitari de Bellvitge, Barcelona.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
<wicri:orgArea>Department of Rheumatology L'Hospitalet de Llobregat, Hospital Universitari de Bellvitge</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Calvet, Joan" sort="Calvet, Joan" uniqKey="Calvet J" first="Joan" last="Calvet">Joan Calvet</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Consorci Corporació Sanitària Parc Taulí, Sabadell, Catalunya.</nlm:affiliation>
<wicri:noCountry code="subField">Catalunya</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Moriano Morales, Clara" sort="Moriano Morales, Clara" uniqKey="Moriano Morales C" first="Clara" last="Moriano Morales">Clara Moriano Morales</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital de Leon, Leon.</nlm:affiliation>
<wicri:noCountry code="subField">Leon</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ramon Vazquez Rodriguez, Tomas" sort="Ramon Vazquez Rodriguez, Tomas" uniqKey="Ramon Vazquez Rodriguez T" first="Tomas" last="Ramon Vazquez-Rodriguez">Tomas Ramon Vazquez-Rodriguez</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Lucus Augusti, Lugo, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Garcia De La Pe A, Paloma" sort="Garcia De La Pe A, Paloma" uniqKey="Garcia De La Pe A P" first="Paloma" last="Garcia De La Pe A">Paloma Garcia De La Pe A</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario HM Sanchinarro, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario HM Sanchinarro</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Boh Rquez, Cristina" sort="Boh Rquez, Cristina" uniqKey="Boh Rquez C" first="Cristina" last="Boh Rquez">Cristina Boh Rquez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Principe de Asturias, Alcala de Henares, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Principe de Asturias, Alcala de Henares</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Andreu Sanchez, Jose Luis" sort="Andreu Sanchez, Jose Luis" uniqKey="Andreu Sanchez J" first="José Luis" last="Andreu-Sánchez">José Luis Andreu-Sánchez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Puerta del Hierro Majadahonda, Majadahonda, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Puerta del Hierro Majadahonda, Majadahonda</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Cobo Iba Ez, Tatiana" sort="Cobo Iba Ez, Tatiana" uniqKey="Cobo Iba Ez T" first="Tatiana" last="Cobo-Iba Ez">Tatiana Cobo-Iba Ez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Infanta Sofia, San Sebastian de los Reyes, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Infanta Sofia, San Sebastian de los Reyes</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Bonilla, Gema" sort="Bonilla, Gema" uniqKey="Bonilla G" first="Gema" last="Bonilla">Gema Bonilla</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario La Paz, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario La Paz</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Lozano Rivas, Nuria" sort="Lozano Rivas, Nuria" uniqKey="Lozano Rivas N" first="Nuria" last="Lozano-Rivas">Nuria Lozano-Rivas</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.</nlm:affiliation>
<wicri:noCountry code="subField">Murcia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Montilla, Carlos" sort="Montilla, Carlos" uniqKey="Montilla C" first="Carlos" last="Montilla">Carlos Montilla</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Clínico de Salamanca, Salamanca, Castilla y León.</nlm:affiliation>
<wicri:noCountry code="subField">Castilla y León</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Toyos, Francisco Javier" sort="Toyos, Francisco Javier" uniqKey="Toyos F" first="Francisco Javier" last="Toyos">Francisco Javier Toyos</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Virgen Macarena, Sevilla, Andalucía.</nlm:affiliation>
<wicri:noCountry code="subField">Andalucía</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="De La Fuente, Jose Luis Marenco" sort="De La Fuente, Jose Luis Marenco" uniqKey="De La Fuente J" first="Jose Luis Marenco" last="De La Fuente">Jose Luis Marenco De La Fuente</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Valme, Sevilla, Andalucía.</nlm:affiliation>
<wicri:noCountry code="subField">Andalucía</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Exp Sito, Lorena" sort="Exp Sito, Lorena" uniqKey="Exp Sito L" first="Lorena" last="Exp Sito">Lorena Exp Sito</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Canarias, La Laguna, Canarias.</nlm:affiliation>
<wicri:noCountry code="subField">Canarias</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ruiz Lucea, Maria Esther" sort="Ruiz Lucea, Maria Esther" uniqKey="Ruiz Lucea M" first="María Esther" last="Ruiz-Lucea">María Esther Ruiz-Lucea</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital de Basurto, Basurto, País Vasco.</nlm:affiliation>
<wicri:noCountry code="subField">País Vasco</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vals, Elia" sort="Vals, Elia" uniqKey="Vals E" first="Elia" last="Vals">Elia Vals</name>
<affiliation><nlm:affiliation>ReumatologíaValencia, Hospital Universitario Dr Peset, Comunitat Valenciana.</nlm:affiliation>
<wicri:noCountry code="subField">Comunitat Valenciana</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Manero Ruiz, Javier" sort="Manero Ruiz, Javier" uniqKey="Manero Ruiz J" first="Javier" last="Manero-Ruiz">Javier Manero-Ruiz</name>
<affiliation><nlm:affiliation>Reumatología Zaragoza, Hospital Universitario Miguel Servet, Aragón.</nlm:affiliation>
<wicri:noCountry code="subField">Aragón</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bernal Vidal, Jose A" sort="Bernal Vidal, Jose A" uniqKey="Bernal Vidal J" first="Jose A" last="Bernal-Vidal">Jose A. Bernal-Vidal</name>
<affiliation><nlm:affiliation>Reumatología, Hospital General Universitario de Alicante, Valencia, Alicante.</nlm:affiliation>
<wicri:noCountry code="subField">Alicante</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rua Figueroa, I Igo" sort="Rua Figueroa, I Igo" uniqKey="Rua Figueroa I" first="I Igo" last="Rua-Figueroa">I Igo Rua-Figueroa</name>
<affiliation wicri:level="1"><nlm:affiliation>Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria</wicri:regionArea>
<wicri:noRegion>Las Palmas de Gran Canaria</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry.</title>
<author><name sortKey="Mena Vazquez, Natalia" sort="Mena Vazquez, Natalia" uniqKey="Mena Vazquez N" first="Natalia" last="Mena-Vázquez">Natalia Mena-Vázquez</name>
<affiliation><nlm:affiliation>Instituto de Investigación Biomédica de Málaga - IBIMA, Malaga.</nlm:affiliation>
<wicri:noCountry code="subField">Malaga</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fernandez Nebro, Antonio" sort="Fernandez Nebro, Antonio" uniqKey="Fernandez Nebro A" first="Antonio" last="Fernández-Nebro">Antonio Fernández-Nebro</name>
<affiliation><nlm:affiliation>Instituto de Investigación Biomédica de Málaga - IBIMA, Malaga.</nlm:affiliation>
<wicri:noCountry code="subField">Malaga</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pego Reigosa, Jose Maria" sort="Pego Reigosa, Jose Maria" uniqKey="Pego Reigosa J" first="José María" last="Pego-Reigosa">José María Pego-Reigosa</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital do Meixoeiro, Vigo, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Galindo, Maria" sort="Galindo, Maria" uniqKey="Galindo M" first="María" last="Galindo">María Galindo</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario 12 de Octubre, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario 12 de Octubre</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Melissa Anzola, Ana" sort="Melissa Anzola, Ana" uniqKey="Melissa Anzola A" first="Ana" last="Melissa-Anzola">Ana Melissa-Anzola</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital General Universitario Gregorio Marañón</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Uriarte Isacelay, Esther" sort="Uriarte Isacelay, Esther" uniqKey="Uriarte Isacelay E" first="Esther" last="Uriarte-Isacelay">Esther Uriarte-Isacelay</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Donostia, San Sebastian, País Vasco.</nlm:affiliation>
<wicri:noCountry code="subField">País Vasco</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Olive Marques, Alejandro" sort="Olive Marques, Alejandro" uniqKey="Olive Marques A" first="Alejandro" last="Olivé-Marqués">Alejandro Olivé-Marqués</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Catalunya.</nlm:affiliation>
<wicri:noCountry code="subField">Catalunya</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Aurrecoechea, Elena" sort="Aurrecoechea, Elena" uniqKey="Aurrecoechea E" first="Elena" last="Aurrecoechea">Elena Aurrecoechea</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Sierrallana, Torrelavega, Cantabria.</nlm:affiliation>
<wicri:noCountry code="subField">Cantabria</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Freire, Mercedes" sort="Freire, Mercedes" uniqKey="Freire M" first="Mercedes" last="Freire">Mercedes Freire</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Juan Canalejo de La Coruña, A Coruna, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tomero, Eva" sort="Tomero, Eva" uniqKey="Tomero E" first="Eva" last="Tomero">Eva Tomero</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de la Princesa, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario de la Princesa</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Garcia Villanueva, Maria Jesus" sort="Garcia Villanueva, Maria Jesus" uniqKey="Garcia Villanueva M" first="María Jesús" last="García-Villanueva">María Jesús García-Villanueva</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Ramon y Cajal, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Ramon y Cajal</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Stoye, Claudia" sort="Stoye, Claudia" uniqKey="Stoye C" first="Claudia" last="Stoye">Claudia Stoye</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital de Navarra, Pamplona, Navarra.</nlm:affiliation>
<wicri:noCountry code="subField">Navarra</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Salas Heredia, Esteban" sort="Salas Heredia, Esteban" uniqKey="Salas Heredia E" first="Esteban" last="Salas-Heredia">Esteban Salas-Heredia</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Marina Baixa, Villajoyosa, Valencia.</nlm:affiliation>
<wicri:noCountry code="subField">Valencia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bernal Vidal, Jose Antonio" sort="Bernal Vidal, Jose Antonio" uniqKey="Bernal Vidal J" first="Jose Antonio" last="Bernal-Vidal">Jose Antonio Bernal-Vidal</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital General Universitario de Alicante, Alicante, Valencia.</nlm:affiliation>
<wicri:noCountry code="subField">Valencia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Salgado, Eva" sort="Salgado, Eva" uniqKey="Salgado E" first="Eva" last="Salgado">Eva Salgado</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Complejo Hospitalario de Orense, Ourense, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Blanco, Ricardo" sort="Blanco, Ricardo" uniqKey="Blanco R" first="Ricardo" last="Blanco">Ricardo Blanco</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Marques de Valdecilla, Santander, Cantabria.</nlm:affiliation>
<wicri:noCountry code="subField">Cantabria</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Javier Novoa, Francisco" sort="Javier Novoa, Francisco" uniqKey="Javier Novoa F" first="Francisco" last="Javier Novoa">Francisco Javier Novoa</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria.</nlm:affiliation>
<wicri:noCountry code="subField">Las Palmas de Gran Canaria</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Iba Ez Barcelo, M Nica" sort="Iba Ez Barcelo, M Nica" uniqKey="Iba Ez Barcelo M" first="M Nica" last="Ibá Ez-Barcelo">M Nica Ibá Ez-Barcelo</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Son Llatzer, Palma de Mallorca, Illes Balears.</nlm:affiliation>
<wicri:noCountry code="subField">Illes Balears</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Torrente Segarra, Vicente" sort="Torrente Segarra, Vicente" uniqKey="Torrente Segarra V" first="Vicente" last="Torrente-Segarra">Vicente Torrente-Segarra</name>
<affiliation wicri:level="3"><nlm:affiliation>Rheumatology Vilafranca del Penedes, Hospital Comarcal de l'Alt Penedes, Barcelona.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
<wicri:orgArea>Rheumatology Vilafranca del Penedes, Hospital Comarcal de l'Alt Penedes</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Narvaez, Javier" sort="Narvaez, Javier" uniqKey="Narvaez J" first="Javier" last="Narvaez">Javier Narvaez</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology L'Hospitalet de Llobregat, Hospital Universitari de Bellvitge, Barcelona.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
<wicri:orgArea>Department of Rheumatology L'Hospitalet de Llobregat, Hospital Universitari de Bellvitge</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Calvet, Joan" sort="Calvet, Joan" uniqKey="Calvet J" first="Joan" last="Calvet">Joan Calvet</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Consorci Corporació Sanitària Parc Taulí, Sabadell, Catalunya.</nlm:affiliation>
<wicri:noCountry code="subField">Catalunya</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Moriano Morales, Clara" sort="Moriano Morales, Clara" uniqKey="Moriano Morales C" first="Clara" last="Moriano Morales">Clara Moriano Morales</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital de Leon, Leon.</nlm:affiliation>
<wicri:noCountry code="subField">Leon</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ramon Vazquez Rodriguez, Tomas" sort="Ramon Vazquez Rodriguez, Tomas" uniqKey="Ramon Vazquez Rodriguez T" first="Tomas" last="Ramon Vazquez-Rodriguez">Tomas Ramon Vazquez-Rodriguez</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Lucus Augusti, Lugo, Galicia.</nlm:affiliation>
<wicri:noCountry code="subField">Galicia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Garcia De La Pe A, Paloma" sort="Garcia De La Pe A, Paloma" uniqKey="Garcia De La Pe A P" first="Paloma" last="Garcia De La Pe A">Paloma Garcia De La Pe A</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario HM Sanchinarro, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario HM Sanchinarro</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Boh Rquez, Cristina" sort="Boh Rquez, Cristina" uniqKey="Boh Rquez C" first="Cristina" last="Boh Rquez">Cristina Boh Rquez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Principe de Asturias, Alcala de Henares, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Principe de Asturias, Alcala de Henares</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Andreu Sanchez, Jose Luis" sort="Andreu Sanchez, Jose Luis" uniqKey="Andreu Sanchez J" first="José Luis" last="Andreu-Sánchez">José Luis Andreu-Sánchez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Puerta del Hierro Majadahonda, Majadahonda, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Puerta del Hierro Majadahonda, Majadahonda</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Cobo Iba Ez, Tatiana" sort="Cobo Iba Ez, Tatiana" uniqKey="Cobo Iba Ez T" first="Tatiana" last="Cobo-Iba Ez">Tatiana Cobo-Iba Ez</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Infanta Sofia, San Sebastian de los Reyes, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario Infanta Sofia, San Sebastian de los Reyes</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Bonilla, Gema" sort="Bonilla, Gema" uniqKey="Bonilla G" first="Gema" last="Bonilla">Gema Bonilla</name>
<affiliation wicri:level="3"><nlm:affiliation>Departamento de Reumatología, Hospital Universitario La Paz, Madrid.</nlm:affiliation>
<country>Espagne</country>
<placeName><settlement type="city">Madrid</settlement>
<region nuts="2" type="region">Communauté de Madrid</region>
</placeName>
<wicri:orgArea>Departamento de Reumatología, Hospital Universitario La Paz</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Lozano Rivas, Nuria" sort="Lozano Rivas, Nuria" uniqKey="Lozano Rivas N" first="Nuria" last="Lozano-Rivas">Nuria Lozano-Rivas</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.</nlm:affiliation>
<wicri:noCountry code="subField">Murcia</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Montilla, Carlos" sort="Montilla, Carlos" uniqKey="Montilla C" first="Carlos" last="Montilla">Carlos Montilla</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Clínico de Salamanca, Salamanca, Castilla y León.</nlm:affiliation>
<wicri:noCountry code="subField">Castilla y León</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Toyos, Francisco Javier" sort="Toyos, Francisco Javier" uniqKey="Toyos F" first="Francisco Javier" last="Toyos">Francisco Javier Toyos</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario Virgen Macarena, Sevilla, Andalucía.</nlm:affiliation>
<wicri:noCountry code="subField">Andalucía</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="De La Fuente, Jose Luis Marenco" sort="De La Fuente, Jose Luis Marenco" uniqKey="De La Fuente J" first="Jose Luis Marenco" last="De La Fuente">Jose Luis Marenco De La Fuente</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Valme, Sevilla, Andalucía.</nlm:affiliation>
<wicri:noCountry code="subField">Andalucía</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Exp Sito, Lorena" sort="Exp Sito, Lorena" uniqKey="Exp Sito L" first="Lorena" last="Exp Sito">Lorena Exp Sito</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital Universitario de Canarias, La Laguna, Canarias.</nlm:affiliation>
<wicri:noCountry code="subField">Canarias</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ruiz Lucea, Maria Esther" sort="Ruiz Lucea, Maria Esther" uniqKey="Ruiz Lucea M" first="María Esther" last="Ruiz-Lucea">María Esther Ruiz-Lucea</name>
<affiliation><nlm:affiliation>Departamento de Reumatología, Hospital de Basurto, Basurto, País Vasco.</nlm:affiliation>
<wicri:noCountry code="subField">País Vasco</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Vals, Elia" sort="Vals, Elia" uniqKey="Vals E" first="Elia" last="Vals">Elia Vals</name>
<affiliation><nlm:affiliation>ReumatologíaValencia, Hospital Universitario Dr Peset, Comunitat Valenciana.</nlm:affiliation>
<wicri:noCountry code="subField">Comunitat Valenciana</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Manero Ruiz, Javier" sort="Manero Ruiz, Javier" uniqKey="Manero Ruiz J" first="Javier" last="Manero-Ruiz">Javier Manero-Ruiz</name>
<affiliation><nlm:affiliation>Reumatología Zaragoza, Hospital Universitario Miguel Servet, Aragón.</nlm:affiliation>
<wicri:noCountry code="subField">Aragón</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bernal Vidal, Jose A" sort="Bernal Vidal, Jose A" uniqKey="Bernal Vidal J" first="Jose A" last="Bernal-Vidal">Jose A. Bernal-Vidal</name>
<affiliation><nlm:affiliation>Reumatología, Hospital General Universitario de Alicante, Valencia, Alicante.</nlm:affiliation>
<wicri:noCountry code="subField">Alicante</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Rua Figueroa, I Igo" sort="Rua Figueroa, I Igo" uniqKey="Rua Figueroa I" first="I Igo" last="Rua-Figueroa">I Igo Rua-Figueroa</name>
<affiliation wicri:level="1"><nlm:affiliation>Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria</wicri:regionArea>
<wicri:noRegion>Las Palmas de Gran Canaria</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Rheumatology (Oxford, England)</title>
<idno type="eISSN">1462-0332</idno>
<imprint><date when="2019" type="published">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">This article estimates the frequency of polyautoimmunity and associated factors in a large retrospective cohort of patients with SLE.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">31808534</PMID>
<DateRevised><Year>2019</Year>
<Month>12</Month>
<Day>06</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1462-0332</ISSN>
<JournalIssue CitedMedium="Internet"><PubDate><Year>2019</Year>
<Month>Dec</Month>
<Day>06</Day>
</PubDate>
</JournalIssue>
<Title>Rheumatology (Oxford, England)</Title>
<ISOAbbreviation>Rheumatology (Oxford)</ISOAbbreviation>
</Journal>
<ArticleTitle>Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry.</ArticleTitle>
<ELocationID EIdType="pii" ValidYN="Y">kez562</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1093/rheumatology/kez562</ELocationID>
<Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">This article estimates the frequency of polyautoimmunity and associated factors in a large retrospective cohort of patients with SLE.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">RELESSER (Spanish Society of Rheumatology Lupus Registry) is a nationwide multicentre, hospital-based registry of SLE patients. This is a cross-sectional study. The main variable was polyautoimmunity, which was defined as the co-occurrence of SLE and another autoimmune disease, such as autoimmune thyroiditis, RA, scleroderma, inflammatory myopathy and MCTD. We also recorded the presence of multiple autoimmune syndrome, secondary SS, secondary APS and a family history of autoimmune disease. Multiple logistic regression analysis was performed to investigate possible risk factors for polyautoimmunity.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of the 3679 patients who fulfilled the criteria for SLE, 502 (13.6%) had polyautoimmunity. The most frequent types were autoimmune thyroiditis (7.9%), other systemic autoimmune diseases (6.2%), secondary SS (14.1%) and secondary APS (13.7%). Multiple autoimmune syndrome accounted for 10.2% of all cases of polyautoimmunity. A family history was recorded in 11.8%. According to the multivariate analysis, the factors associated with polyautoimmunity were female sex [odds ratio (95% CI), 1.72 (1.07, 2.72)], RP [1.63 (1.29, 2.05)], interstitial lung disease [3.35 (1.84, 6.01)], Jaccoud arthropathy [1.92 (1.40, 2.63)], anti-Ro/SSA and/or anti-La/SSB autoantibodies [2.03 (1.55, 2.67)], anti-RNP antibodies [1.48 (1.16, 1.90)], MTX [1.67 (1.26, 2.18)] and antimalarial drugs [0.50 (0.38, 0.67)].</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Patients with SLE frequently present polyautoimmunity. We observed clinical and analytical characteristics associated with polyautoimmunity. Our finding that antimalarial drugs protected against polyautoimmunity should be verified in future studies.</AbstractText>
<CopyrightInformation>© The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Rheumatology.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mena-Vázquez</LastName>
<ForeName>Natalia</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Instituto de Investigación Biomédica de Málaga - IBIMA, Malaga.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>UGC de Reumatología, Hospital Regional Universitario de Málaga, Málaga.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fernández-Nebro</LastName>
<ForeName>Antonio</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Instituto de Investigación Biomédica de Málaga - IBIMA, Malaga.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>UGC de Reumatología, Hospital Regional Universitario de Málaga, Málaga.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Departamento de Medicina, Universidad de Málaga, Málaga.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pego-Reigosa</LastName>
<ForeName>José María</ForeName>
<Initials>JM</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital do Meixoeiro, Vigo, Galicia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Galindo</LastName>
<ForeName>María</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario 12 de Octubre, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Melissa-Anzola</LastName>
<ForeName>Ana</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital General Universitario Gregorio Marañón, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Uriarte-Isacelay</LastName>
<ForeName>Esther</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario de Donostia, San Sebastian, País Vasco.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Olivé-Marqués</LastName>
<ForeName>Alejandro</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitari Germans Trias i Pujol, Badalona, Catalunya.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Aurrecoechea</LastName>
<ForeName>Elena</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Sierrallana, Torrelavega, Cantabria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Freire</LastName>
<ForeName>Mercedes</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Juan Canalejo de La Coruña, A Coruna, Galicia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tomero</LastName>
<ForeName>Eva</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario de la Princesa, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>García-Villanueva</LastName>
<ForeName>María Jesús</ForeName>
<Initials>MJ</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario Ramon y Cajal, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Stoye</LastName>
<ForeName>Claudia</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital de Navarra, Pamplona, Navarra.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Salas-Heredia</LastName>
<ForeName>Esteban</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Marina Baixa, Villajoyosa, Valencia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bernal-Vidal</LastName>
<ForeName>Jose Antonio</ForeName>
<Initials>JA</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital General Universitario de Alicante, Alicante, Valencia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Salgado</LastName>
<ForeName>Eva</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Complejo Hospitalario de Orense, Ourense, Galicia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Blanco</LastName>
<ForeName>Ricardo</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario Marques de Valdecilla, Santander, Cantabria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Javier Novoa</LastName>
<ForeName>Francisco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ibáñez-Barcelo</LastName>
<ForeName>Mónica</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Son Llatzer, Palma de Mallorca, Illes Balears.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Torrente-Segarra</LastName>
<ForeName>Vicente</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Rheumatology Vilafranca del Penedes, Hospital Comarcal de l'Alt Penedes, Barcelona.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Narvaez</LastName>
<ForeName>Javier</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Rheumatology L'Hospitalet de Llobregat, Hospital Universitari de Bellvitge, Barcelona.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Calvet</LastName>
<ForeName>Joan</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Consorci Corporació Sanitària Parc Taulí, Sabadell, Catalunya.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Moriano Morales</LastName>
<ForeName>Clara</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital de Leon, Leon.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ramon Vazquez-Rodriguez</LastName>
<ForeName>Tomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Lucus Augusti, Lugo, Galicia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Garcia de la Peña</LastName>
<ForeName>Paloma</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario HM Sanchinarro, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bohórquez</LastName>
<ForeName>Cristina</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario Principe de Asturias, Alcala de Henares, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Andreu-Sánchez</LastName>
<ForeName>José Luis</ForeName>
<Initials>JL</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario Puerta del Hierro Majadahonda, Majadahonda, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cobo-Ibañez</LastName>
<ForeName>Tatiana</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario Infanta Sofia, San Sebastian de los Reyes, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bonilla</LastName>
<ForeName>Gema</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario La Paz, Madrid.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lozano-Rivas</LastName>
<ForeName>Nuria</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Montilla</LastName>
<ForeName>Carlos</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Clínico de Salamanca, Salamanca, Castilla y León.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Toyos</LastName>
<ForeName>Francisco Javier</ForeName>
<Initials>FJ</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario Virgen Macarena, Sevilla, Andalucía.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>De la Fuente</LastName>
<ForeName>Jose Luis Marenco</ForeName>
<Initials>JLM</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario de Valme, Sevilla, Andalucía.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Expósito</LastName>
<ForeName>Lorena</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital Universitario de Canarias, La Laguna, Canarias.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ruiz-Lucea</LastName>
<ForeName>María Esther</ForeName>
<Initials>ME</Initials>
<AffiliationInfo><Affiliation>Departamento de Reumatología, Hospital de Basurto, Basurto, País Vasco.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Vals</LastName>
<ForeName>Elia</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>ReumatologíaValencia, Hospital Universitario Dr Peset, Comunitat Valenciana.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Manero-Ruiz</LastName>
<ForeName>Javier</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Reumatología Zaragoza, Hospital Universitario Miguel Servet, Aragón.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bernal-Vidal</LastName>
<ForeName>Jose A</ForeName>
<Initials>JA</Initials>
<AffiliationInfo><Affiliation>Reumatología, Hospital General Universitario de Alicante, Valencia, Alicante.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rua-Figueroa</LastName>
<ForeName>Iñigo</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Reumatología, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria, Spain.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2019</Year>
<Month>12</Month>
<Day>06</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Rheumatology (Oxford)</MedlineTA>
<NlmUniqueID>100883501</NlmUniqueID>
<ISSNLinking>1462-0324</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">multiple autoimmune syndrome</Keyword>
<Keyword MajorTopicYN="N">polyautoimmunity</Keyword>
<Keyword MajorTopicYN="N">systemic lupus erythematosus</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year>
<Month>05</Month>
<Day>27</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2019</Year>
<Month>10</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2019</Year>
<Month>12</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>12</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>12</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>aheadofprint</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">31808534</ArticleId>
<ArticleId IdType="pii">5662444</ArticleId>
<ArticleId IdType="doi">10.1093/rheumatology/kez562</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Espagne</li>
</country>
<region><li>Catalogne</li>
<li>Communauté de Madrid</li>
</region>
<settlement><li>Barcelone</li>
<li>Madrid</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Aurrecoechea, Elena" sort="Aurrecoechea, Elena" uniqKey="Aurrecoechea E" first="Elena" last="Aurrecoechea">Elena Aurrecoechea</name>
<name sortKey="Bernal Vidal, Jose A" sort="Bernal Vidal, Jose A" uniqKey="Bernal Vidal J" first="Jose A" last="Bernal-Vidal">Jose A. Bernal-Vidal</name>
<name sortKey="Bernal Vidal, Jose Antonio" sort="Bernal Vidal, Jose Antonio" uniqKey="Bernal Vidal J" first="Jose Antonio" last="Bernal-Vidal">Jose Antonio Bernal-Vidal</name>
<name sortKey="Blanco, Ricardo" sort="Blanco, Ricardo" uniqKey="Blanco R" first="Ricardo" last="Blanco">Ricardo Blanco</name>
<name sortKey="Calvet, Joan" sort="Calvet, Joan" uniqKey="Calvet J" first="Joan" last="Calvet">Joan Calvet</name>
<name sortKey="De La Fuente, Jose Luis Marenco" sort="De La Fuente, Jose Luis Marenco" uniqKey="De La Fuente J" first="Jose Luis Marenco" last="De La Fuente">Jose Luis Marenco De La Fuente</name>
<name sortKey="Exp Sito, Lorena" sort="Exp Sito, Lorena" uniqKey="Exp Sito L" first="Lorena" last="Exp Sito">Lorena Exp Sito</name>
<name sortKey="Fernandez Nebro, Antonio" sort="Fernandez Nebro, Antonio" uniqKey="Fernandez Nebro A" first="Antonio" last="Fernández-Nebro">Antonio Fernández-Nebro</name>
<name sortKey="Freire, Mercedes" sort="Freire, Mercedes" uniqKey="Freire M" first="Mercedes" last="Freire">Mercedes Freire</name>
<name sortKey="Iba Ez Barcelo, M Nica" sort="Iba Ez Barcelo, M Nica" uniqKey="Iba Ez Barcelo M" first="M Nica" last="Ibá Ez-Barcelo">M Nica Ibá Ez-Barcelo</name>
<name sortKey="Javier Novoa, Francisco" sort="Javier Novoa, Francisco" uniqKey="Javier Novoa F" first="Francisco" last="Javier Novoa">Francisco Javier Novoa</name>
<name sortKey="Lozano Rivas, Nuria" sort="Lozano Rivas, Nuria" uniqKey="Lozano Rivas N" first="Nuria" last="Lozano-Rivas">Nuria Lozano-Rivas</name>
<name sortKey="Manero Ruiz, Javier" sort="Manero Ruiz, Javier" uniqKey="Manero Ruiz J" first="Javier" last="Manero-Ruiz">Javier Manero-Ruiz</name>
<name sortKey="Mena Vazquez, Natalia" sort="Mena Vazquez, Natalia" uniqKey="Mena Vazquez N" first="Natalia" last="Mena-Vázquez">Natalia Mena-Vázquez</name>
<name sortKey="Montilla, Carlos" sort="Montilla, Carlos" uniqKey="Montilla C" first="Carlos" last="Montilla">Carlos Montilla</name>
<name sortKey="Moriano Morales, Clara" sort="Moriano Morales, Clara" uniqKey="Moriano Morales C" first="Clara" last="Moriano Morales">Clara Moriano Morales</name>
<name sortKey="Olive Marques, Alejandro" sort="Olive Marques, Alejandro" uniqKey="Olive Marques A" first="Alejandro" last="Olivé-Marqués">Alejandro Olivé-Marqués</name>
<name sortKey="Pego Reigosa, Jose Maria" sort="Pego Reigosa, Jose Maria" uniqKey="Pego Reigosa J" first="José María" last="Pego-Reigosa">José María Pego-Reigosa</name>
<name sortKey="Ramon Vazquez Rodriguez, Tomas" sort="Ramon Vazquez Rodriguez, Tomas" uniqKey="Ramon Vazquez Rodriguez T" first="Tomas" last="Ramon Vazquez-Rodriguez">Tomas Ramon Vazquez-Rodriguez</name>
<name sortKey="Ruiz Lucea, Maria Esther" sort="Ruiz Lucea, Maria Esther" uniqKey="Ruiz Lucea M" first="María Esther" last="Ruiz-Lucea">María Esther Ruiz-Lucea</name>
<name sortKey="Salas Heredia, Esteban" sort="Salas Heredia, Esteban" uniqKey="Salas Heredia E" first="Esteban" last="Salas-Heredia">Esteban Salas-Heredia</name>
<name sortKey="Salgado, Eva" sort="Salgado, Eva" uniqKey="Salgado E" first="Eva" last="Salgado">Eva Salgado</name>
<name sortKey="Stoye, Claudia" sort="Stoye, Claudia" uniqKey="Stoye C" first="Claudia" last="Stoye">Claudia Stoye</name>
<name sortKey="Toyos, Francisco Javier" sort="Toyos, Francisco Javier" uniqKey="Toyos F" first="Francisco Javier" last="Toyos">Francisco Javier Toyos</name>
<name sortKey="Uriarte Isacelay, Esther" sort="Uriarte Isacelay, Esther" uniqKey="Uriarte Isacelay E" first="Esther" last="Uriarte-Isacelay">Esther Uriarte-Isacelay</name>
<name sortKey="Vals, Elia" sort="Vals, Elia" uniqKey="Vals E" first="Elia" last="Vals">Elia Vals</name>
</noCountry>
<country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Galindo, Maria" sort="Galindo, Maria" uniqKey="Galindo M" first="María" last="Galindo">María Galindo</name>
</region>
<name sortKey="Andreu Sanchez, Jose Luis" sort="Andreu Sanchez, Jose Luis" uniqKey="Andreu Sanchez J" first="José Luis" last="Andreu-Sánchez">José Luis Andreu-Sánchez</name>
<name sortKey="Boh Rquez, Cristina" sort="Boh Rquez, Cristina" uniqKey="Boh Rquez C" first="Cristina" last="Boh Rquez">Cristina Boh Rquez</name>
<name sortKey="Bonilla, Gema" sort="Bonilla, Gema" uniqKey="Bonilla G" first="Gema" last="Bonilla">Gema Bonilla</name>
<name sortKey="Cobo Iba Ez, Tatiana" sort="Cobo Iba Ez, Tatiana" uniqKey="Cobo Iba Ez T" first="Tatiana" last="Cobo-Iba Ez">Tatiana Cobo-Iba Ez</name>
<name sortKey="Garcia De La Pe A, Paloma" sort="Garcia De La Pe A, Paloma" uniqKey="Garcia De La Pe A P" first="Paloma" last="Garcia De La Pe A">Paloma Garcia De La Pe A</name>
<name sortKey="Garcia Villanueva, Maria Jesus" sort="Garcia Villanueva, Maria Jesus" uniqKey="Garcia Villanueva M" first="María Jesús" last="García-Villanueva">María Jesús García-Villanueva</name>
<name sortKey="Melissa Anzola, Ana" sort="Melissa Anzola, Ana" uniqKey="Melissa Anzola A" first="Ana" last="Melissa-Anzola">Ana Melissa-Anzola</name>
<name sortKey="Narvaez, Javier" sort="Narvaez, Javier" uniqKey="Narvaez J" first="Javier" last="Narvaez">Javier Narvaez</name>
<name sortKey="Rua Figueroa, I Igo" sort="Rua Figueroa, I Igo" uniqKey="Rua Figueroa I" first="I Igo" last="Rua-Figueroa">I Igo Rua-Figueroa</name>
<name sortKey="Tomero, Eva" sort="Tomero, Eva" uniqKey="Tomero E" first="Eva" last="Tomero">Eva Tomero</name>
<name sortKey="Torrente Segarra, Vicente" sort="Torrente Segarra, Vicente" uniqKey="Torrente Segarra V" first="Vicente" last="Torrente-Segarra">Vicente Torrente-Segarra</name>
</country>
</tree>
</affiliations>
</record>
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