Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers
Identifieur interne : 000A15 ( Pmc/Curation ); précédent : 000A14; suivant : 000A16Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers
Auteurs : Suet Yen Chong [Singapour] ; Choon Keong Lee [Singapour] ; Chenyuan Huang [Singapour] ; Yi Hsuan Ou [Singapour] ; Christopher J. Charles [Singapour] ; Arthur Mark Richards [Singapour] ; Yub Raj Neupane [Singapour] ; Maria Vazquez Pavon [Singapour] ; Olga Zharkova [Singapour] ; Giorgia Pastorin [Singapour] ; Jiong-Wei Wang [Singapour]Source :
- International Journal of Molecular Sciences [ 1422-0067 ] ; 2019.
Abstract
Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality globally. The emerging role of extracellular vesicles (EVs) in intercellular communication has stimulated renewed interest in exploring the potential application of EVs as tools for diagnosis, prognosis, and therapy in CVD. The ubiquitous nature of EVs in biological fluids presents a technological advantage compared to current diagnostic tools by virtue of their notable stability. EV contents, such as proteins and microRNAs, represent specific signatures of cellular activation or injury. This feature positions EVs as an alternative source of biomarkers. Furthermore, their intrinsic activity and immunomodulatory properties offer EVs unique opportunities to act as therapeutic agents per se or to serve as drug delivery carriers by acting as miniaturized vehicles incorporating bioactive molecules. In this article, we aim to review the recent advances and applications of EV-based biomarkers and therapeutics. In addition, the potential of EVs as a drug delivery and theranostic platform for CVD will also be discussed.
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DOI: 10.3390/ijms20133272
PubMed: 31277271
PubMed Central: 6650854
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Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-ijms-20-03272">Cardiovascular Research Institute (CVRI), National University Heart Centre Singapore (NUHCS), Singapore 117599, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Cardiovascular Research Institute (CVRI), National University Heart Centre Singapore (NUHCS), Singapore 117599</wicri:regionArea></affiliation></author><author><name sortKey="Pastorin, Giorgia" sort="Pastorin, Giorgia" uniqKey="Pastorin G" first="Giorgia" last="Pastorin">Giorgia Pastorin</name><affiliation wicri:level="1"><nlm:aff id="af3-ijms-20-03272">Department of Pharmacy, National University of Singapore, Singapore 117543, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Pharmacy, National University of Singapore, Singapore 117543</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Jiong Wei" sort="Wang, Jiong Wei" uniqKey="Wang J" first="Jiong-Wei" last="Wang">Jiong-Wei Wang</name><affiliation wicri:level="1"><nlm:aff id="af1-ijms-20-03272">Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af2-ijms-20-03272">Cardiovascular Research Institute (CVRI), National University Heart Centre Singapore (NUHCS), Singapore 117599, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Cardiovascular Research Institute (CVRI), National University Heart Centre Singapore (NUHCS), Singapore 117599</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af5-ijms-20-03272">Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593</wicri:regionArea></affiliation></author></analytic><series><title level="j">International Journal of Molecular Sciences</title><idno type="eISSN">1422-0067</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality globally. The emerging role of extracellular vesicles (EVs) in intercellular communication has stimulated renewed interest in exploring the potential application of EVs as tools for diagnosis, prognosis, and therapy in CVD. The ubiquitous nature of EVs in biological fluids presents a technological advantage compared to current diagnostic tools by virtue of their notable stability. EV contents, such as proteins and microRNAs, represent specific signatures of cellular activation or injury. This feature positions EVs as an alternative source of biomarkers. Furthermore, their intrinsic activity and immunomodulatory properties offer EVs unique opportunities to act as therapeutic agents per se or to serve as drug delivery carriers by acting as miniaturized vehicles incorporating bioactive molecules. In this article, we aim to review the recent advances and applications of EV-based biomarkers and therapeutics. In addition, the potential of EVs as a drug delivery and theranostic platform for CVD will also be discussed.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Mendis, S" uniqKey="Mendis S">S. Mendis</name></author><author><name sortKey="Puska, P" uniqKey="Puska P">P. Puska</name></author><author><name sortKey="Norrving, B" uniqKey="Norrving B">B. Norrving</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roth, G A" uniqKey="Roth G">G.A. Roth</name></author><author><name sortKey="Johnson, C" uniqKey="Johnson C">C. Johnson</name></author><author><name sortKey="Abajobir, A" uniqKey="Abajobir A">A. Abajobir</name></author><author><name sortKey="Abd Allah, F" uniqKey="Abd Allah F">F. Abd-Allah</name></author><author><name sortKey="Abera, S F" uniqKey="Abera S">S.F. Abera</name></author><author><name sortKey="Abyu, G" uniqKey="Abyu G">G. Abyu</name></author><author><name sortKey="Ahmed, M" uniqKey="Ahmed M">M. Ahmed</name></author><author><name sortKey="Aksut, B" uniqKey="Aksut B">B. Aksut</name></author><author><name sortKey="Alam, T" uniqKey="Alam T">T. Alam</name></author><author><name sortKey="Alam, K" uniqKey="Alam K">K. Alam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="White, H D" uniqKey="White H">H.D. White</name></author><author><name sortKey="Chew, D P" uniqKey="Chew D">D.P. Chew</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Richards, A M" uniqKey="Richards A">A.M. Richards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loyer, X" uniqKey="Loyer X">X. Loyer</name></author><author><name sortKey="Zlatanova, I" uniqKey="Zlatanova I">I. Zlatanova</name></author><author><name sortKey="Devue, C" uniqKey="Devue C">C. Devue</name></author><author><name sortKey="Yin, M" uniqKey="Yin M">M. Yin</name></author><author><name sortKey="Howangyin, K Y" uniqKey="Howangyin K">K.-Y. Howangyin</name></author><author><name sortKey="Klaihmon, P" uniqKey="Klaihmon P">P. Klaihmon</name></author><author><name sortKey="Guerin, C L" uniqKey="Guerin C">C.L. Guerin</name></author><author><name sortKey="Kheloufi, M" uniqKey="Kheloufi M">M. Kheloufi</name></author><author><name sortKey="Vilar, J" uniqKey="Vilar J">J. Vilar</name></author><author><name sortKey="Zannis, K" uniqKey="Zannis K">K. Zannis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sluijter, J P G" uniqKey="Sluijter J">J.P.G. Sluijter</name></author><author><name sortKey="Davidson, S M" uniqKey="Davidson S">S.M. Davidson</name></author><author><name sortKey="Boulanger, C M" uniqKey="Boulanger C">C.M. Boulanger</name></author><author><name sortKey="Buzas, E I" uniqKey="Buzas E">E.I. Buzás</name></author><author><name sortKey="De Kleijn, D P V" uniqKey="De Kleijn D">D.P.V. De Kleijn</name></author><author><name sortKey="Engel, F B" uniqKey="Engel F">F.B. Engel</name></author><author><name sortKey="Giricz, Z" uniqKey="Giricz Z">Z. Giricz</name></author><author><name sortKey="Hausenloy, D J" uniqKey="Hausenloy D">D.J. Hausenloy</name></author><author><name sortKey="Kishore, R" uniqKey="Kishore R">R. Kishore</name></author><author><name sortKey="Lecour, S" uniqKey="Lecour S">S. Lecour</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boulanger, C M" uniqKey="Boulanger C">C.M. Boulanger</name></author><author><name sortKey="Loyer, X" uniqKey="Loyer X">X. Loyer</name></author><author><name sortKey="Rautou, P E" uniqKey="Rautou P">P.E. Rautou</name></author><author><name sortKey="Amabile, N" uniqKey="Amabile N">N. Amabile</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ribeiro Rodrigues, T M" uniqKey="Ribeiro Rodrigues T">T.M. Ribeiro-Rodrigues</name></author><author><name sortKey="Laundos, T L" uniqKey="Laundos T">T.L. Laundos</name></author><author><name sortKey="Pereira Carvalho, R" uniqKey="Pereira Carvalho R">R. Pereira-Carvalho</name></author><author><name sortKey="Batista Almeida, D" uniqKey="Batista Almeida D">D. Batista-Almeida</name></author><author><name sortKey="Pereira, R" uniqKey="Pereira R">R. Pereira</name></author><author><name sortKey="Coelho Santos, V" uniqKey="Coelho Santos V">V. Coelho-Santos</name></author><author><name sortKey="Silva, A P" uniqKey="Silva A">A.P. Silva</name></author><author><name sortKey="Fernandes, R" uniqKey="Fernandes R">R. Fernandes</name></author><author><name sortKey="Zuzarte, M" uniqKey="Zuzarte M">M. Zuzarte</name></author><author><name sortKey="Enguita, F J" uniqKey="Enguita F">F.J. Enguita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arraud, N" uniqKey="Arraud N">N. Arraud</name></author><author><name sortKey="Linares, R" uniqKey="Linares R">R. Linares</name></author><author><name sortKey="Tan, S" uniqKey="Tan S">S. Tan</name></author><author><name sortKey="Gounou, C" uniqKey="Gounou C">C. Gounou</name></author><author><name sortKey="Pasquet, J M" uniqKey="Pasquet J">J.-M. Pasquet</name></author><author><name sortKey="Mornet, S" uniqKey="Mornet S">S. Mornet</name></author><author><name sortKey="Brisson, A R" uniqKey="Brisson A">A.R. Brisson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Merchant, M L" uniqKey="Merchant M">M.L. Merchant</name></author><author><name sortKey="Rood, I M" uniqKey="Rood I">I.M. Rood</name></author><author><name sortKey="Deegens, J K J" uniqKey="Deegens J">J.K.J. Deegens</name></author><author><name sortKey="Klein, J B" uniqKey="Klein J">J.B. Klein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoog, J L" uniqKey="Hoog J">J.L. Höög</name></author><author><name sortKey="Lotvall, J" uniqKey="Lotvall J">J. Lötvall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zonneveld, M I" uniqKey="Zonneveld M">M.I. Zonneveld</name></author><author><name sortKey="Brisson, A R" uniqKey="Brisson A">A.R. Brisson</name></author><author><name sortKey="Van Herwijnen, M J" uniqKey="Van Herwijnen M">M.J. Van Herwijnen</name></author><author><name sortKey="Tan, S" uniqKey="Tan S">S. Tan</name></author><author><name sortKey="Van De Lest, C H" uniqKey="Van De Lest C">C.H. Van De Lest</name></author><author><name sortKey="Redegeld, F A" uniqKey="Redegeld F">F.A. Redegeld</name></author><author><name sortKey="Garssen, J" uniqKey="Garssen J">J. Garssen</name></author><author><name sortKey="Wauben, M H" uniqKey="Wauben M">M.H. Wauben</name></author><author><name sortKey="Nolte Hoen, E N" uniqKey="Nolte Hoen E">E.N. Nolte-’t Hoen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iwai, K" uniqKey="Iwai K">K. Iwai</name></author><author><name sortKey="Minamisawa, T" uniqKey="Minamisawa T">T. Minamisawa</name></author><author><name sortKey="Suga, K" uniqKey="Suga K">K. Suga</name></author><author><name sortKey="Yajima, Y" uniqKey="Yajima Y">Y. Yajima</name></author><author><name sortKey="Shiba, K" uniqKey="Shiba K">K. Shiba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolf, P" uniqKey="Wolf P">P. Wolf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnstone, R M" uniqKey="Johnstone R">R.M. Johnstone</name></author><author><name sortKey="Adam, M" uniqKey="Adam M">M. Adam</name></author><author><name sortKey="Hammond, J R" uniqKey="Hammond J">J.R. Hammond</name></author><author><name sortKey="Orr, L" uniqKey="Orr L">L. Orr</name></author><author><name sortKey="Turbide, C" uniqKey="Turbide C">C. Turbide</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tkach, M" uniqKey="Tkach M">M. Tkach</name></author><author><name sortKey="Thery, C" uniqKey="Thery C">C. Théry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Niel, G" uniqKey="Van Niel G">G. Van Niel</name></author><author><name sortKey="D Ngelo, G" uniqKey="D Ngelo G">G. D’Angelo</name></author><author><name sortKey="Raposo, G" uniqKey="Raposo G">G. Raposo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gould, S J" uniqKey="Gould S">S.J. Gould</name></author><author><name sortKey="Raposo, G" uniqKey="Raposo G">G. Raposo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lotvall, J" uniqKey="Lotvall J">J. Lötvall</name></author><author><name sortKey="Hill, A F" uniqKey="Hill A">A.F. Hill</name></author><author><name sortKey="Hochberg, F" uniqKey="Hochberg F">F. Hochberg</name></author><author><name sortKey="Buzas, E I" uniqKey="Buzas E">E.I. Buzás</name></author><author><name sortKey="Di Vizio, D" uniqKey="Di Vizio D">D. Di Vizio</name></author><author><name sortKey="Gardiner, C" uniqKey="Gardiner C">C. Gardiner</name></author><author><name sortKey="Gho, Y S" uniqKey="Gho Y">Y.S. Gho</name></author><author><name sortKey="Kurochkin, I V" uniqKey="Kurochkin I">I.V. Kurochkin</name></author><author><name sortKey="Mathivanan, S" uniqKey="Mathivanan S">S. Mathivanan</name></author><author><name sortKey="Quesenberry, P" uniqKey="Quesenberry P">P. Quesenberry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thery, C" uniqKey="Thery C">C. Théry</name></author><author><name sortKey="Witwer, K W" uniqKey="Witwer K">K.W. Witwer</name></author><author><name sortKey="Aikawa, E" uniqKey="Aikawa E">E. Aikawa</name></author><author><name sortKey="Alcaraz, M J" uniqKey="Alcaraz M">M.J. Alcaraz</name></author><author><name sortKey="Anderson, J D" uniqKey="Anderson J">J.D. Anderson</name></author><author><name sortKey="Andriantsitohaina, R" uniqKey="Andriantsitohaina R">R. Andriantsitohaina</name></author><author><name sortKey="Antoniou, A" uniqKey="Antoniou A">A. Antoniou</name></author><author><name sortKey="Arab, T" uniqKey="Arab T">T. Arab</name></author><author><name sortKey="Archer, F" uniqKey="Archer F">F. Archer</name></author><author><name sortKey="Atkin Smith, G K" uniqKey="Atkin Smith G">G.K. Atkin-Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harding, C V" uniqKey="Harding C">C.V. Harding</name></author><author><name sortKey="Heuser, J E" uniqKey="Heuser J">J.E. Heuser</name></author><author><name sortKey="Stahl, P D" uniqKey="Stahl P">P.D. Stahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ortiz, A" uniqKey="Ortiz A">A. Ortiz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Katzmann, D J" uniqKey="Katzmann D">D.J. Katzmann</name></author><author><name sortKey="Babst, M" uniqKey="Babst M">M. Babst</name></author><author><name sortKey="Emr, S D" uniqKey="Emr S">S.D. Emr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, J W W" uniqKey="Wang J">J.-W.W. Wang</name></author><author><name sortKey="Zhang, Y N N" uniqKey="Zhang Y">Y.-N.N. Zhang</name></author><author><name sortKey="Sze, S K" uniqKey="Sze S">S.K. Sze</name></author><author><name sortKey="Van De Weg, S M" uniqKey="Van De Weg S">S.M. Van De Weg</name></author><author><name sortKey="Vernooij, F" uniqKey="Vernooij F">F. Vernooij</name></author><author><name sortKey="Schoneveld, A H" uniqKey="Schoneveld A">A.H. Schoneveld</name></author><author><name sortKey="Tan, S H H" uniqKey="Tan S">S.-H.H. Tan</name></author><author><name sortKey="Versteeg, H H" uniqKey="Versteeg H">H.H. Versteeg</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Lam, C S P P" uniqKey="Lam C">C.S.P.P. Lam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuana, Y" uniqKey="Yuana Y">Y. Yuana</name></author><author><name sortKey="Levels, J" uniqKey="Levels J">J. Levels</name></author><author><name sortKey="Grootemaat, A" uniqKey="Grootemaat A">A. Grootemaat</name></author><author><name sortKey="Sturk, A" uniqKey="Sturk A">A. Sturk</name></author><author><name sortKey="Nieuwland, R" uniqKey="Nieuwland R">R. Nieuwland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aatonen, M" uniqKey="Aatonen M">M. Aatonen</name></author><author><name sortKey="Valkonen, S" uniqKey="Valkonen S">S. Valkonen</name></author><author><name sortKey="Boing, A" uniqKey="Boing A">A. Böing</name></author><author><name sortKey="Yuana, Y" uniqKey="Yuana Y">Y. Yuana</name></author><author><name sortKey="Nieuwland, R" uniqKey="Nieuwland R">R. Nieuwland</name></author><author><name sortKey="Siljander, P" uniqKey="Siljander P">P. Siljander</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dickhout, A" uniqKey="Dickhout A">A. Dickhout</name></author><author><name sortKey="Koenen, R R" uniqKey="Koenen R">R.R. Koenen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zaborowski, M P" uniqKey="Zaborowski M">M.P. Zaborowski</name></author><author><name sortKey="Balaj, L" uniqKey="Balaj L">L. Balaj</name></author><author><name sortKey="Breakefield, X O" uniqKey="Breakefield X">X.O. Breakefield</name></author><author><name sortKey="Lai, C P" uniqKey="Lai C">C.P. Lai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Palmisano, G" uniqKey="Palmisano G">G. Palmisano</name></author><author><name sortKey="Jensen, S S" uniqKey="Jensen S">S.S. Jensen</name></author><author><name sortKey="Le Bihan, M C" uniqKey="Le Bihan M">M.-C. Le Bihan</name></author><author><name sortKey="Laine, J" uniqKey="Laine J">J. Lainé</name></author><author><name sortKey="Mcguire, J N" uniqKey="Mcguire J">J.N. McGuire</name></author><author><name sortKey="Pociot, F" uniqKey="Pociot F">F. Pociot</name></author><author><name sortKey="Larsen, M R" uniqKey="Larsen M">M.R. Larsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morita, E" uniqKey="Morita E">E. Morita</name></author><author><name sortKey="Sandrin, V" uniqKey="Sandrin V">V. Sandrin</name></author><author><name sortKey="Chung, H Y" uniqKey="Chung H">H.-Y. Chung</name></author><author><name sortKey="Morham, S G" uniqKey="Morham S">S.G. Morham</name></author><author><name sortKey="Gygi, S P" uniqKey="Gygi S">S.P. Gygi</name></author><author><name sortKey="Rodesch, C K" uniqKey="Rodesch C">C.K. Rodesch</name></author><author><name sortKey="Sundquist, W I" uniqKey="Sundquist W">W.I. Sundquist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buzas, E I" uniqKey="Buzas E">E.I. Buzas</name></author><author><name sortKey="Gyorgy, B" uniqKey="Gyorgy B">B. György</name></author><author><name sortKey="Nagy, G" uniqKey="Nagy G">G. Nagy</name></author><author><name sortKey="Falus, A" uniqKey="Falus A">A. Falus</name></author><author><name sortKey="Gay, S" uniqKey="Gay S">S. Gay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tucher, C" uniqKey="Tucher C">C. Tucher</name></author><author><name sortKey="Bode, K" uniqKey="Bode K">K. Bode</name></author><author><name sortKey="Schiller, P" uniqKey="Schiller P">P. Schiller</name></author><author><name sortKey="Cla En, L" uniqKey="Cla En L">L. Claßen</name></author><author><name sortKey="Birr, C" uniqKey="Birr C">C. Birr</name></author><author><name sortKey="Souto Carneiro, M M" uniqKey="Souto Carneiro M">M.M. Souto-Carneiro</name></author><author><name sortKey="Blank, N" uniqKey="Blank N">N. Blank</name></author><author><name sortKey="Lorenz, H M" uniqKey="Lorenz H">H.-M. Lorenz</name></author><author><name sortKey="Schiller, M" uniqKey="Schiller M">M. Schiller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Graner, M W" uniqKey="Graner M">M.W. Graner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bank, I E" uniqKey="Bank I">I.E. Bank</name></author><author><name sortKey="Chan, M Y" uniqKey="Chan M">M.Y. Chan</name></author><author><name sortKey="Mosterd, A" uniqKey="Mosterd A">A. Mosterd</name></author><author><name sortKey="Lam, C S" uniqKey="Lam C">C.S. Lam</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Gijsberts, C M" uniqKey="Gijsberts C">C.M. Gijsberts</name></author><author><name sortKey="Sze, S K" uniqKey="Sze S">S.K. Sze</name></author><author><name sortKey="Wang, J W" uniqKey="Wang J">J.-W. Wang</name></author><author><name sortKey="Lim, S K" uniqKey="Lim S">S.K. Lim</name></author><author><name sortKey="De Kleijn, D P" uniqKey="De Kleijn D">D.P. De Kleijn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Turchinovich, A" uniqKey="Turchinovich A">A. Turchinovich</name></author><author><name sortKey="Drapkina, O" uniqKey="Drapkina O">O. Drapkina</name></author><author><name sortKey="Tonevitsky, A" uniqKey="Tonevitsky A">A. Tonevitsky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kreimer, S" uniqKey="Kreimer S">S. Kreimer</name></author><author><name sortKey="Belov, A M" uniqKey="Belov A">A.M. Belov</name></author><author><name sortKey="Ghiran, I" uniqKey="Ghiran I">I. Ghiran</name></author><author><name sortKey="Murthy, S K" uniqKey="Murthy S">S.K. Murthy</name></author><author><name sortKey="Frank, D A" uniqKey="Frank D">D.A. Frank</name></author><author><name sortKey="Ivanov, A R" uniqKey="Ivanov A">A.R. Ivanov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosa Fernandes, L" uniqKey="Rosa Fernandes L">L. Rosa-Fernandes</name></author><author><name sortKey="Rocha, V B" uniqKey="Rocha V">V.B. Rocha</name></author><author><name sortKey="Carregari, V C" uniqKey="Carregari V">V.C. Carregari</name></author><author><name sortKey="Urbani, A" uniqKey="Urbani A">A. Urbani</name></author><author><name sortKey="Palmisano, G" uniqKey="Palmisano G">G. Palmisano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fu, Q" uniqKey="Fu Q">Q. Fu</name></author><author><name sortKey="Zhu, J" uniqKey="Zhu J">J. Zhu</name></author><author><name sortKey="Van Eyk, J E" uniqKey="Van Eyk J">J.E. Van Eyk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kohler, K" uniqKey="Kohler K">K. Köhler</name></author><author><name sortKey="Seitz, H" uniqKey="Seitz H">H. Seitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Hoog, V C" uniqKey="De Hoog V">V.C. De Hoog</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Schoneveld, A H" uniqKey="Schoneveld A">A.H. Schoneveld</name></author><author><name sortKey="Wang, J W" uniqKey="Wang J">J.-W. Wang</name></author><author><name sortKey="Van De Weg, S M" uniqKey="Van De Weg S">S.M. Van De Weg</name></author><author><name sortKey="Sze, S K" uniqKey="Sze S">S.K. Sze</name></author><author><name sortKey="Van Keulen, J K" uniqKey="Van Keulen J">J.K. Van Keulen</name></author><author><name sortKey="Hoes, A W" uniqKey="Hoes A">A.W. Hoes</name></author><author><name sortKey="Den Ruijter, H M" uniqKey="Den Ruijter H">H.M. Den Ruijter</name></author><author><name sortKey="De Kleijn, D P" uniqKey="De Kleijn D">D.P. De Kleijn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanhai, D A" uniqKey="Kanhai D">D.A. Kanhai</name></author><author><name sortKey="Visseren, F L J" uniqKey="Visseren F">F.L.J. Visseren</name></author><author><name sortKey="Van Der Graaf, Y" uniqKey="Van Der Graaf Y">Y. Van Der Graaf</name></author><author><name sortKey="Schoneveld, A H" uniqKey="Schoneveld A">A.H. Schoneveld</name></author><author><name sortKey="Catanzariti, L M" uniqKey="Catanzariti L">L.M. Catanzariti</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Kappelle, L J" uniqKey="Kappelle L">L.J. Kappelle</name></author><author><name sortKey="Uiterwaal, C S P M" uniqKey="Uiterwaal C">C.S.P.M. Uiterwaal</name></author><author><name sortKey="Lim, S K" uniqKey="Lim S">S.K. Lim</name></author><author><name sortKey="Sze, S K" uniqKey="Sze S">S.K. Sze</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Y N" uniqKey="Zhang Y">Y.N. Zhang</name></author><author><name sortKey="Vernooij, F" uniqKey="Vernooij F">F. Vernooij</name></author><author><name sortKey="Ibrahim, I" uniqKey="Ibrahim I">I. Ibrahim</name></author><author><name sortKey="Ooi, S" uniqKey="Ooi S">S. Ooi</name></author><author><name sortKey="Gijsberts, C M" uniqKey="Gijsberts C">C.M. Gijsberts</name></author><author><name sortKey="Schoneveld, A H" uniqKey="Schoneveld A">A.H. Schoneveld</name></author><author><name sortKey="Sen, K W" uniqKey="Sen K">K.W. Sen</name></author><author><name sortKey="Den Ruijter, H M" uniqKey="Den Ruijter H">H.M. Den Ruijter</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Richards, A M" uniqKey="Richards A">A.M. Richards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Verbree Willemsen, L" uniqKey="Verbree Willemsen L">L. Verbree-Willemsen</name></author><author><name sortKey="Zhang, Y N N" uniqKey="Zhang Y">Y.-N.N. Zhang</name></author><author><name sortKey="Gijsberts, C M" uniqKey="Gijsberts C">C.M. Gijsberts</name></author><author><name sortKey="Schoneveld, A H" uniqKey="Schoneveld A">A.H. Schoneveld</name></author><author><name sortKey="Wang, J W W" uniqKey="Wang J">J.-W.W. Wang</name></author><author><name sortKey="Lam, C S P" uniqKey="Lam C">C.S.P. Lam</name></author><author><name sortKey="Vernooij, F" uniqKey="Vernooij F">F. Vernooij</name></author><author><name sortKey="Bots, M L" uniqKey="Bots M">M.L. Bots</name></author><author><name sortKey="Peelen, L M" uniqKey="Peelen L">L.M. Peelen</name></author><author><name sortKey="Grobbee, D E" uniqKey="Grobbee D">D.E. Grobbee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wendt, S" uniqKey="Wendt S">S. Wendt</name></author><author><name sortKey="Goetzenich, A" uniqKey="Goetzenich A">A. Goetzenich</name></author><author><name sortKey="Goettsch, C" uniqKey="Goettsch C">C. Goettsch</name></author><author><name sortKey="Stoppe, C" uniqKey="Stoppe C">C. Stoppe</name></author><author><name sortKey="Bleilevens, C" uniqKey="Bleilevens C">C. Bleilevens</name></author><author><name sortKey="Kraemer, S" uniqKey="Kraemer S">S. Kraemer</name></author><author><name sortKey="Benstoem, C" uniqKey="Benstoem C">C. Benstoem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, S" uniqKey="Zhou S">S. Zhou</name></author><author><name sortKey="Jin, J" uniqKey="Jin J">J. Jin</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z. Zhang</name></author><author><name sortKey="Freedman, J H" uniqKey="Freedman J">J.H. Freedman</name></author><author><name sortKey="Zheng, Y" uniqKey="Zheng Y">Y. Zheng</name></author><author><name sortKey="Cai, L" uniqKey="Cai L">L. Cai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Navickas, R" uniqKey="Navickas R">R. Navickas</name></author><author><name sortKey="Gal, D" uniqKey="Gal D">D. Gal</name></author><author><name sortKey="Laucevi Ius, A" uniqKey="Laucevi Ius A">A. Laucevičius</name></author><author><name sortKey="Taparauskait, A" uniqKey="Taparauskait A">A. Taparauskaitė</name></author><author><name sortKey="Zdanyt, M" uniqKey="Zdanyt M">M. Zdanytė</name></author><author><name sortKey="Holvoet, P" uniqKey="Holvoet P">P. Holvoet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wahid, F" uniqKey="Wahid F">F. Wahid</name></author><author><name sortKey="Shehzad, A" uniqKey="Shehzad A">A. Shehzad</name></author><author><name sortKey="Khan, T" uniqKey="Khan T">T. Khan</name></author><author><name sortKey="Kim, Y Y" uniqKey="Kim Y">Y.Y. Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kosaka, N" uniqKey="Kosaka N">N. Kosaka</name></author><author><name sortKey="Iguchi, H" uniqKey="Iguchi H">H. Iguchi</name></author><author><name sortKey="Yoshioka, Y" uniqKey="Yoshioka Y">Y. Yoshioka</name></author><author><name sortKey="Takeshita, F" uniqKey="Takeshita F">F. Takeshita</name></author><author><name sortKey="Matsuki, Y" uniqKey="Matsuki Y">Y. Matsuki</name></author><author><name sortKey="Ochiya, T" uniqKey="Ochiya T">T. Ochiya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bartel, D P" uniqKey="Bartel D">D.P. Bartel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hammond, S M" uniqKey="Hammond S">S.M. Hammond</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Das, S" uniqKey="Das S">S. Das</name></author><author><name sortKey="Halushka, M K" uniqKey="Halushka M">M.K. Halushka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, M" uniqKey="Cheng M">M. Cheng</name></author><author><name sortKey="Yang, J" uniqKey="Yang J">J. Yang</name></author><author><name sortKey="Zhao, X" uniqKey="Zhao X">X. Zhao</name></author><author><name sortKey="Zhang, E" uniqKey="Zhang E">E. Zhang</name></author><author><name sortKey="Zeng, Q" uniqKey="Zeng Q">Q. Zeng</name></author><author><name sortKey="Yu, Y" uniqKey="Yu Y">Y. Yu</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author><author><name sortKey="Wu, B" uniqKey="Wu B">B. Wu</name></author><author><name sortKey="Yi, G" uniqKey="Yi G">G. Yi</name></author><author><name sortKey="Mao, X" uniqKey="Mao X">X. Mao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yin, C" uniqKey="Yin C">C. Yin</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Kukreja, R C" uniqKey="Kukreja R">R.C. Kukreja</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hullinger, T G" uniqKey="Hullinger T">T.G. Hullinger</name></author><author><name sortKey="Montgomery, R L" uniqKey="Montgomery R">R.L. Montgomery</name></author><author><name sortKey="Seto, A G" uniqKey="Seto A">A.G. Seto</name></author><author><name sortKey="Dickinson, B A" uniqKey="Dickinson B">B.A. Dickinson</name></author><author><name sortKey="Semus, H M" uniqKey="Semus H">H.M. Semus</name></author><author><name sortKey="Lynch, J M" uniqKey="Lynch J">J.M. Lynch</name></author><author><name sortKey="Dalby, C M" uniqKey="Dalby C">C.M. Dalby</name></author><author><name sortKey="Robinson, K" uniqKey="Robinson K">K. Robinson</name></author><author><name sortKey="Stack, C" uniqKey="Stack C">C. Stack</name></author><author><name sortKey="Latimer, P A" uniqKey="Latimer P">P.A. Latimer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Spannbauer, A" uniqKey="Spannbauer A">A. Spannbauer</name></author><author><name sortKey="Traxler, D" uniqKey="Traxler D">D. Traxler</name></author><author><name sortKey="Lukovic, D" uniqKey="Lukovic D">D. Lukovic</name></author><author><name sortKey="Zlabinger, K" uniqKey="Zlabinger K">K. Zlabinger</name></author><author><name sortKey="Winkler, J" uniqKey="Winkler J">J. Winkler</name></author><author><name sortKey="Gugerell, A" uniqKey="Gugerell A">A. Gugerell</name></author><author><name sortKey="Ferdinandy, P" uniqKey="Ferdinandy P">P. Ferdinandy</name></author><author><name sortKey="Hausenloy, D J" uniqKey="Hausenloy D">D.J. Hausenloy</name></author><author><name sortKey="Pavo, N" uniqKey="Pavo N">N. Pavo</name></author><author><name sortKey="Emmert, M Y" uniqKey="Emmert M">M.Y. Emmert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mayourian, J" uniqKey="Mayourian J">J. Mayourian</name></author><author><name sortKey="Cashman, T J" uniqKey="Cashman T">T.J. Cashman</name></author><author><name sortKey="Ceholski, D K" uniqKey="Ceholski D">D.K. Ceholski</name></author><author><name sortKey="Johnson, B V" uniqKey="Johnson B">B.V. Johnson</name></author><author><name sortKey="Sachs, D" uniqKey="Sachs D">D. Sachs</name></author><author><name sortKey="Kaji, D A" uniqKey="Kaji D">D.A. Kaji</name></author><author><name sortKey="Sahoo, S" uniqKey="Sahoo S">S. Sahoo</name></author><author><name sortKey="Hare, J M" uniqKey="Hare J">J.M. Hare</name></author><author><name sortKey="Hajjar, R J" uniqKey="Hajjar R">R.J. Hajjar</name></author><author><name sortKey="Sobie, E A" uniqKey="Sobie E">E.A. Sobie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mun, D" uniqKey="Mun D">D. Mun</name></author><author><name sortKey="Kim, H" uniqKey="Kim H">H. Kim</name></author><author><name sortKey="Kang, J Y" uniqKey="Kang J">J.-Y. Kang</name></author><author><name sortKey="Park, H" uniqKey="Park H">H. Park</name></author><author><name sortKey="Park, H" uniqKey="Park H">H. Park</name></author><author><name sortKey="Lee, S H" uniqKey="Lee S">S.-H. Lee</name></author><author><name sortKey="Yun, N" uniqKey="Yun N">N. Yun</name></author><author><name sortKey="Joung, B" uniqKey="Joung B">B. Joung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deddens, J C" uniqKey="Deddens J">J.C. Deddens</name></author><author><name sortKey="Vrijsen, K R" uniqKey="Vrijsen K">K.R. Vrijsen</name></author><author><name sortKey="Colijn, J M" uniqKey="Colijn J">J.M. Colijn</name></author><author><name sortKey="Oerlemans, M I" uniqKey="Oerlemans M">M.I. Oerlemans</name></author><author><name sortKey="Metz, C H G" uniqKey="Metz C">C.H.G. Metz</name></author><author><name sortKey="Van Der Vlist, E J" uniqKey="Van Der Vlist E">E.J. Van Der Vlist</name></author><author><name sortKey="Nolte Hoen, E N M" uniqKey="Nolte Hoen E">E.N.M. Nolte-’t Hoen</name></author><author><name sortKey="Den Ouden, K" uniqKey="Den Ouden K">K. Den Ouden</name></author><author><name sortKey="Jansen Of Lorkeers, S J" uniqKey="Jansen Of Lorkeers S">S.J. Jansen Of Lorkeers</name></author><author><name sortKey="Van Der Spoel, T I G" uniqKey="Van Der Spoel T">T.I.G. Van Der Spoel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, J" uniqKey="Zhou J">J. Zhou</name></author><author><name sortKey="Chen, L" uniqKey="Chen L">L. Chen</name></author><author><name sortKey="Chen, B" uniqKey="Chen B">B. Chen</name></author><author><name sortKey="Huang, S" uniqKey="Huang S">S. Huang</name></author><author><name sortKey="Zeng, C" uniqKey="Zeng C">C. Zeng</name></author><author><name sortKey="Wu, H" uniqKey="Wu H">H. Wu</name></author><author><name sortKey="Chen, C" uniqKey="Chen C">C. Chen</name></author><author><name sortKey="Long, F" uniqKey="Long F">F. Long</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y. Chen</name></author><author><name sortKey="Song, Y" uniqKey="Song Y">Y. Song</name></author><author><name sortKey="Huang, J" uniqKey="Huang J">J. Huang</name></author><author><name sortKey="Qu, M" uniqKey="Qu M">M. Qu</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Geng, J" uniqKey="Geng J">J. Geng</name></author><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z. Zhang</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author><author><name sortKey="Yang, G Y" uniqKey="Yang G">G.-Y. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, L" uniqKey="Cheng L">L. Cheng</name></author><author><name sortKey="Sharples, R A" uniqKey="Sharples R">R.A. Sharples</name></author><author><name sortKey="Scicluna, B J" uniqKey="Scicluna B">B.J. Scicluna</name></author><author><name sortKey="Hill, A F" uniqKey="Hill A">A.F. Hill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author><author><name sortKey="Xu, B" uniqKey="Xu B">B. Xu</name></author><author><name sortKey="Liu, Y L" uniqKey="Liu Y">Y.-L. Liu</name></author><author><name sortKey="Liu, Z" uniqKey="Liu Z">Z. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, T" uniqKey="Wu T">T. Wu</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y. Chen</name></author><author><name sortKey="Du, Y" uniqKey="Du Y">Y. Du</name></author><author><name sortKey="Tao, J" uniqKey="Tao J">J. Tao</name></author><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z. Zhou</name></author><author><name sortKey="Yang, Z" uniqKey="Yang Z">Z. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matsumoto, S" uniqKey="Matsumoto S">S. Matsumoto</name></author><author><name sortKey="Sakata, Y" uniqKey="Sakata Y">Y. Sakata</name></author><author><name sortKey="Suna, S" uniqKey="Suna S">S. Suna</name></author><author><name sortKey="Nakatani, D" uniqKey="Nakatani D">D. Nakatani</name></author><author><name sortKey="Usami, M" uniqKey="Usami M">M. Usami</name></author><author><name sortKey="Hara, M" uniqKey="Hara M">M. Hara</name></author><author><name sortKey="Kitamura, T" uniqKey="Kitamura T">T. Kitamura</name></author><author><name sortKey="Hamasaki, T" uniqKey="Hamasaki T">T. Hamasaki</name></author><author><name sortKey="Nanto, S" uniqKey="Nanto S">S. Nanto</name></author><author><name sortKey="Kawahara, Y" uniqKey="Kawahara Y">Y. Kawahara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brook, R D" uniqKey="Brook R">R.D. Brook</name></author><author><name sortKey="Rajagopalan, S" uniqKey="Rajagopalan S">S. Rajagopalan</name></author><author><name sortKey="Pope, C A" uniqKey="Pope C">C.A. Pope</name></author><author><name sortKey="Brook, J R" uniqKey="Brook J">J.R. Brook</name></author><author><name sortKey="Bhatnagar, A" uniqKey="Bhatnagar A">A. Bhatnagar</name></author><author><name sortKey="Diez Roux, A V" uniqKey="Diez Roux A">A.V. Diez-Roux</name></author><author><name sortKey="Holguin, F" uniqKey="Holguin F">F. Holguin</name></author><author><name sortKey="Hong, Y" uniqKey="Hong Y">Y. Hong</name></author><author><name sortKey="Luepker, R V" uniqKey="Luepker R">R.V. Luepker</name></author><author><name sortKey="Mittleman, M A" uniqKey="Mittleman M">M.A. Mittleman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yue, W" uniqKey="Yue W">W. Yue</name></author><author><name sortKey="Tong, L" uniqKey="Tong L">L. Tong</name></author><author><name sortKey="Liu, X" uniqKey="Liu X">X. Liu</name></author><author><name sortKey="Weng, X" uniqKey="Weng X">X. Weng</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Dudley, S C" uniqKey="Dudley S">S.C. Dudley</name></author><author><name sortKey="Weir, E K" uniqKey="Weir E">E.K. Weir</name></author><author><name sortKey="Ding, W" uniqKey="Ding W">W. Ding</name></author><author><name sortKey="Lu, Z" uniqKey="Lu Z">Z. Lu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rodosthenous, R S" uniqKey="Rodosthenous R">R.S. Rodosthenous</name></author><author><name sortKey="Kloog, I" uniqKey="Kloog I">I. Kloog</name></author><author><name sortKey="Colicino, E" uniqKey="Colicino E">E. Colicino</name></author><author><name sortKey="Zhong, J" uniqKey="Zhong J">J. Zhong</name></author><author><name sortKey="Herrera, L A" uniqKey="Herrera L">L.A. Herrera</name></author><author><name sortKey="Vokonas, P" uniqKey="Vokonas P">P. Vokonas</name></author><author><name sortKey="Schwartz, J" uniqKey="Schwartz J">J. Schwartz</name></author><author><name sortKey="Baccarelli, A A" uniqKey="Baccarelli A">A.A. Baccarelli</name></author><author><name sortKey="Prada, D" uniqKey="Prada D">D. Prada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pergoli, L" uniqKey="Pergoli L">L. Pergoli</name></author><author><name sortKey="Cantone, L" uniqKey="Cantone L">L. Cantone</name></author><author><name sortKey="Favero, C" uniqKey="Favero C">C. Favero</name></author><author><name sortKey="Angelici, L" uniqKey="Angelici L">L. Angelici</name></author><author><name sortKey="Iodice, S" uniqKey="Iodice S">S. Iodice</name></author><author><name sortKey="Pinatel, E" uniqKey="Pinatel E">E. Pinatel</name></author><author><name sortKey="Hoxha, M" uniqKey="Hoxha M">M. Hoxha</name></author><author><name sortKey="Dioni, L" uniqKey="Dioni L">L. Dioni</name></author><author><name sortKey="Letizia, M" uniqKey="Letizia M">M. Letizia</name></author><author><name sortKey="Albetti, B" uniqKey="Albetti B">B. Albetti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rodosthenous, R S" uniqKey="Rodosthenous R">R.S. Rodosthenous</name></author><author><name sortKey="Coull, B A" uniqKey="Coull B">B.A. Coull</name></author><author><name sortKey="Lu, Q" uniqKey="Lu Q">Q. Lu</name></author><author><name sortKey="Vokonas, P S" uniqKey="Vokonas P">P.S. Vokonas</name></author><author><name sortKey="Schwartz, J D" uniqKey="Schwartz J">J.D. Schwartz</name></author><author><name sortKey="Baccarelli, A A" uniqKey="Baccarelli A">A.A. Baccarelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bollati, V" uniqKey="Bollati V">V. Bollati</name></author><author><name sortKey="Angelici, L" uniqKey="Angelici L">L. Angelici</name></author><author><name sortKey="Rizzo, G" uniqKey="Rizzo G">G. Rizzo</name></author><author><name sortKey="Pergoli, L" uniqKey="Pergoli L">L. Pergoli</name></author><author><name sortKey="Rota, F" uniqKey="Rota F">F. Rota</name></author><author><name sortKey="Hoxha, M" uniqKey="Hoxha M">M. Hoxha</name></author><author><name sortKey="Nordio, F" uniqKey="Nordio F">F. Nordio</name></author><author><name sortKey="Bonzini, M" uniqKey="Bonzini M">M. Bonzini</name></author><author><name sortKey="Tarantini, L" uniqKey="Tarantini L">L. Tarantini</name></author><author><name sortKey="Cantone, L" uniqKey="Cantone L">L. Cantone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hulsmans, M" uniqKey="Hulsmans M">M. Hulsmans</name></author><author><name sortKey="Holvoet, P" uniqKey="Holvoet P">P. Holvoet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bittl, J A" uniqKey="Bittl J">J.A. Bittl</name></author><author><name sortKey="Baber, U" uniqKey="Baber U">U. Baber</name></author><author><name sortKey="Bradley, S M" uniqKey="Bradley S">S.M. Bradley</name></author><author><name sortKey="Wijeysundera, D N" uniqKey="Wijeysundera D">D.N. Wijeysundera</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Emanueli, C" uniqKey="Emanueli C">C. Emanueli</name></author><author><name sortKey="Shearn, A I U" uniqKey="Shearn A">A.I.U. Shearn</name></author><author><name sortKey="Laftah, A" uniqKey="Laftah A">A. Laftah</name></author><author><name sortKey="Fiorentino, F" uniqKey="Fiorentino F">F. Fiorentino</name></author><author><name sortKey="Reeves, B C" uniqKey="Reeves B">B.C. Reeves</name></author><author><name sortKey="Beltrami, C" uniqKey="Beltrami C">C. Beltrami</name></author><author><name sortKey="Mumford, A" uniqKey="Mumford A">A. Mumford</name></author><author><name sortKey="Clayton, A" uniqKey="Clayton A">A. Clayton</name></author><author><name sortKey="Gurney, M" uniqKey="Gurney M">M. Gurney</name></author><author><name sortKey="Shantikumar, S" uniqKey="Shantikumar S">S. Shantikumar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z. Wang</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Shen, J" uniqKey="Shen J">J. Shen</name></author><author><name sortKey="Tian, D" uniqKey="Tian D">D. Tian</name></author><author><name sortKey="Ji, Q" uniqKey="Ji Q">Q. Ji</name></author><author><name sortKey="Xia, L" uniqKey="Xia L">L. Xia</name></author><author><name sortKey="Lv, Q" uniqKey="Lv Q">Q. Lv</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yao, Y" uniqKey="Yao Y">Y. Yao</name></author><author><name sortKey="Du, J" uniqKey="Du J">J. Du</name></author><author><name sortKey="Cao, X" uniqKey="Cao X">X. Cao</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Hu, S" uniqKey="Hu S">S. Hu</name></author><author><name sortKey="Zheng, Z" uniqKey="Zheng Z">Z. Zheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Richards, A M" uniqKey="Richards A">A.M. Richards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, S" uniqKey="Sharma S">S. Sharma</name></author><author><name sortKey="Jackson, P G" uniqKey="Jackson P">P.G. Jackson</name></author><author><name sortKey="Makan, J" uniqKey="Makan J">J. Makan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boukouris, S" uniqKey="Boukouris S">S. Boukouris</name></author><author><name sortKey="Mathivanan, S" uniqKey="Mathivanan S">S. Mathivanan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sluijter, J P G" uniqKey="Sluijter J">J.P.G. Sluijter</name></author><author><name sortKey="Verhage, V" uniqKey="Verhage V">V. Verhage</name></author><author><name sortKey="Deddens, J C" uniqKey="Deddens J">J.C. Deddens</name></author><author><name sortKey="Van Den Akker, F" uniqKey="Van Den Akker F">F. Van Den Akker</name></author><author><name sortKey="Doevendans, P A" uniqKey="Doevendans P">P.A. Doevendans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Velez, P" uniqKey="Velez P">P. Vélez</name></author><author><name sortKey="Pargui A, A" uniqKey="Pargui A A">A. Parguiña</name></author><author><name sortKey="Ocaranza Sanchez, R" uniqKey="Ocaranza Sanchez R">R. Ocaranza-Sánchez</name></author><author><name sortKey="Grigorian Shamagian, L" uniqKey="Grigorian Shamagian L">L. Grigorian-Shamagian</name></author><author><name sortKey="Rosa, I" uniqKey="Rosa I">I. Rosa</name></author><author><name sortKey="Alonso Orgaz, S" uniqKey="Alonso Orgaz S">S. Alonso-Orgaz</name></author><author><name sortKey="De La Cuesta, F" uniqKey="De La Cuesta F">F. De La Cuesta</name></author><author><name sortKey="Guitian, E" uniqKey="Guitian E">E. Guitián</name></author><author><name sortKey="Moreu, J" uniqKey="Moreu J">J. Moreu</name></author><author><name sortKey="Barderas, M" uniqKey="Barderas M">M. Barderas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kranendonk, M E" uniqKey="Kranendonk M">M.E. Kranendonk</name></author><author><name sortKey="De Kleijn, D P" uniqKey="De Kleijn D">D.P. De Kleijn</name></author><author><name sortKey="Kalkhoven, E" uniqKey="Kalkhoven E">E. Kalkhoven</name></author><author><name sortKey="Kanhai, D A" uniqKey="Kanhai D">D.A. Kanhai</name></author><author><name sortKey="Uiterwaal, C S" uniqKey="Uiterwaal C">C.S. Uiterwaal</name></author><author><name sortKey="Van Der Graaf, Y" uniqKey="Van Der Graaf Y">Y. Van Der Graaf</name></author><author><name sortKey="Pasterkamp, G" uniqKey="Pasterkamp G">G. Pasterkamp</name></author><author><name sortKey="Visseren, F L" uniqKey="Visseren F">F.L. Visseren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barrachina, M N" uniqKey="Barrachina M">M.N. Barrachina</name></author><author><name sortKey="Sueiro, A M" uniqKey="Sueiro A">A.M. Sueiro</name></author><author><name sortKey="Casas, V" uniqKey="Casas V">V. Casas</name></author><author><name sortKey="Izquierdo, I" uniqKey="Izquierdo I">I. Izquierdo</name></author><author><name sortKey="Hermida Nogueira, L" uniqKey="Hermida Nogueira L">L. Hermida-Nogueira</name></author><author><name sortKey="Guitian, E" uniqKey="Guitian E">E. Guitián</name></author><author><name sortKey="Casanueva, F F" uniqKey="Casanueva F">F.F. Casanueva</name></author><author><name sortKey="Abian, J" uniqKey="Abian J">J. Abián</name></author><author><name sortKey="Carrascal, M" uniqKey="Carrascal M">M. Carrascal</name></author><author><name sortKey="Pardo, M" uniqKey="Pardo M">M. Pardo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benedikter, B J" uniqKey="Benedikter B">B.J. Benedikter</name></author><author><name sortKey="Bouwman, F G" uniqKey="Bouwman F">F.G. Bouwman</name></author><author><name sortKey="Heinzmann, A C A" uniqKey="Heinzmann A">A.C.A. Heinzmann</name></author><author><name sortKey="Vajen, T" uniqKey="Vajen T">T. Vajen</name></author><author><name sortKey="Mariman, E C" uniqKey="Mariman E">E.C. Mariman</name></author><author><name sortKey="Wouters, E F M" uniqKey="Wouters E">E.F.M. Wouters</name></author><author><name sortKey="Savelkoul, P H M" uniqKey="Savelkoul P">P.H.M. Savelkoul</name></author><author><name sortKey="Koenen, R R" uniqKey="Koenen R">R.R. Koenen</name></author><author><name sortKey="Rohde, G G U" uniqKey="Rohde G">G.G.U. Rohde</name></author><author><name sortKey="Van Oerle, R" uniqKey="Van Oerle R">R. Van Oerle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Battinelli, E M" uniqKey="Battinelli E">E.M. Battinelli</name></author><author><name sortKey="Freedman, J E" uniqKey="Freedman J">J.E. Freedman</name></author><author><name sortKey="Loscalzo, J" uniqKey="Loscalzo J">J. Loscalzo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hajer, G R" uniqKey="Hajer G">G.R. Hajer</name></author><author><name sortKey="Van Haeften, T W" uniqKey="Van Haeften T">T.W. Van Haeften</name></author><author><name sortKey="Visseren, F L J" uniqKey="Visseren F">F.L.J. Visseren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vilahur, G" uniqKey="Vilahur G">G. Vilahur</name></author><author><name sortKey="Ben Aicha, S" uniqKey="Ben Aicha S">S. Ben-Aicha</name></author><author><name sortKey="Badimon, L" uniqKey="Badimon L">L. Badimon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gm, C" uniqKey="Gm C">C. GM</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fadeel, B" uniqKey="Fadeel B">B. Fadeel</name></author><author><name sortKey="Xue, D" uniqKey="Xue D">D. Xue</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trajkovic, K" uniqKey="Trajkovic K">K. Trajkovic</name></author><author><name sortKey="Hsu, C" uniqKey="Hsu C">C. Hsu</name></author><author><name sortKey="Chiantia, S" uniqKey="Chiantia S">S. Chiantia</name></author><author><name sortKey="Rajendran, L" uniqKey="Rajendran L">L. Rajendran</name></author><author><name sortKey="Wenzel, D" uniqKey="Wenzel D">D. Wenzel</name></author><author><name sortKey="Wieland, F" uniqKey="Wieland F">F. Wieland</name></author><author><name sortKey="Schwille, P" uniqKey="Schwille P">P. Schwille</name></author><author><name sortKey="Brugger, B" uniqKey="Brugger B">B. Brugger</name></author><author><name sortKey="Simons, M" uniqKey="Simons M">M. Simons</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skotland, T" uniqKey="Skotland T">T. Skotland</name></author><author><name sortKey="Sandvig, K" uniqKey="Sandvig K">K. Sandvig</name></author><author><name sortKey="Llorente, A" uniqKey="Llorente A">A. Llorente</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Record, M" uniqKey="Record M">M. Record</name></author><author><name sortKey="Silvente Poirot, S" uniqKey="Silvente Poirot S">S. Silvente-Poirot</name></author><author><name sortKey="Poirot, M" uniqKey="Poirot M">M. Poirot</name></author><author><name sortKey="Wakelam, M J O" uniqKey="Wakelam M">M.J.O. Wakelam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Skotland, T" uniqKey="Skotland T">T. Skotland</name></author><author><name sortKey="Hessvik, N P" uniqKey="Hessvik N">N.P. Hessvik</name></author><author><name sortKey="Sandvig, K" uniqKey="Sandvig K">K. Sandvig</name></author><author><name sortKey="Llorente, A" uniqKey="Llorente A">A. Llorente</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kakazu, E" uniqKey="Kakazu E">E. Kakazu</name></author><author><name sortKey="Mauer, A S" uniqKey="Mauer A">A.S. Mauer</name></author><author><name sortKey="Yin, M" uniqKey="Yin M">M. Yin</name></author><author><name sortKey="Malhi, H" uniqKey="Malhi H">H. Malhi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nojima, H" uniqKey="Nojima H">H. Nojima</name></author><author><name sortKey="Freeman, C M" uniqKey="Freeman C">C.M. Freeman</name></author><author><name sortKey="Schuster, R M" uniqKey="Schuster R">R.M. Schuster</name></author><author><name sortKey="Japtok, L" uniqKey="Japtok L">L. Japtok</name></author><author><name sortKey="Kleuser, B" uniqKey="Kleuser B">B. Kleuser</name></author><author><name sortKey="Edwards, M J" uniqKey="Edwards M">M.J. Edwards</name></author><author><name sortKey="Gulbins, E" uniqKey="Gulbins E">E. Gulbins</name></author><author><name sortKey="Lentsch, A B" uniqKey="Lentsch A">A.B. Lentsch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khayrullin, A" uniqKey="Khayrullin A">A. Khayrullin</name></author><author><name sortKey="Krishnan, P" uniqKey="Krishnan P">P. Krishnan</name></author><author><name sortKey="Martinez Nater, L" uniqKey="Martinez Nater L">L. Martinez-Nater</name></author><author><name sortKey="Mendhe, B" uniqKey="Mendhe B">B. Mendhe</name></author><author><name sortKey="Fulzele, S" uniqKey="Fulzele S">S. Fulzele</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name></author><author><name sortKey="Mattison, J" uniqKey="Mattison J">J. Mattison</name></author><author><name sortKey="Hamrick, M" uniqKey="Hamrick M">M. Hamrick</name></author><author><name sortKey="Khayrullin, A" uniqKey="Khayrullin A">A. Khayrullin</name></author><author><name sortKey="Krishnan, P" uniqKey="Krishnan P">P. Krishnan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Carvalho, L P" uniqKey="De Carvalho L">L.P. De Carvalho</name></author><author><name sortKey="Tan, S H" uniqKey="Tan S">S.H. Tan</name></author><author><name sortKey="Ow, G S" uniqKey="Ow G">G.-S. Ow</name></author><author><name sortKey="Tang, Z" uniqKey="Tang Z">Z. Tang</name></author><author><name sortKey="Ching, J" uniqKey="Ching J">J. Ching</name></author><author><name sortKey="Kovalik, J P" uniqKey="Kovalik J">J.-P. Kovalik</name></author><author><name sortKey="Poh, S C" uniqKey="Poh S">S.C. Poh</name></author><author><name sortKey="Chin, C T" uniqKey="Chin C">C.-T. Chin</name></author><author><name sortKey="Richards, A M" uniqKey="Richards A">A.M. Richards</name></author><author><name sortKey="Martinez, E C" uniqKey="Martinez E">E.C. Martinez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stegemann, C" uniqKey="Stegemann C">C. Stegemann</name></author><author><name sortKey="Pechlaner, R" uniqKey="Pechlaner R">R. Pechlaner</name></author><author><name sortKey="Willeit, P" uniqKey="Willeit P">P. Willeit</name></author><author><name sortKey="Langley, S R" uniqKey="Langley S">S.R. Langley</name></author><author><name sortKey="Mangino, M" uniqKey="Mangino M">M. Mangino</name></author><author><name sortKey="Mayr, U" uniqKey="Mayr U">U. Mayr</name></author><author><name sortKey="Menni, C" uniqKey="Menni C">C. Menni</name></author><author><name sortKey="Moayyeri, A" uniqKey="Moayyeri A">A. Moayyeri</name></author><author><name sortKey="Santer, P" uniqKey="Santer P">P. Santer</name></author><author><name sortKey="Rungger, G" uniqKey="Rungger G">G. Rungger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meeusen, J W" uniqKey="Meeusen J">J.W. Meeusen</name></author><author><name sortKey="Donato, L J" uniqKey="Donato L">L.J. Donato</name></author><author><name sortKey="Bryant, S C" uniqKey="Bryant S">S.C. Bryant</name></author><author><name sortKey="Baudhuin, L M" uniqKey="Baudhuin L">L.M. Baudhuin</name></author><author><name sortKey="Berger, P B" uniqKey="Berger P">P.B. Berger</name></author><author><name sortKey="Jaffe, A S" uniqKey="Jaffe A">A.S. Jaffe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peterson, L R" uniqKey="Peterson L">L.R. Peterson</name></author><author><name sortKey="Xanthakis, V" uniqKey="Xanthakis V">V. Xanthakis</name></author><author><name sortKey="Duncan, M S" uniqKey="Duncan M">M.S. Duncan</name></author><author><name sortKey="Gross, S" uniqKey="Gross S">S. Gross</name></author><author><name sortKey="Friedrich, N" uniqKey="Friedrich N">N. Friedrich</name></author><author><name sortKey="Volzke, H" uniqKey="Volzke H">H. Völzke</name></author><author><name sortKey="Felix, S B" uniqKey="Felix S">S.B. Felix</name></author><author><name sortKey="Jiang, H" uniqKey="Jiang H">H. Jiang</name></author><author><name sortKey="Sidhu, R" uniqKey="Sidhu R">R. Sidhu</name></author><author><name sortKey="Nauck, M" uniqKey="Nauck M">M. Nauck</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Menasche, P" uniqKey="Menasche P">P. Menasché</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Karantalis, V" uniqKey="Karantalis V">V. Karantalis</name></author><author><name sortKey="Hare, J M" uniqKey="Hare J">J.M. Hare</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, B" uniqKey="Liu B">B. Liu</name></author><author><name sortKey="Lee, B W" uniqKey="Lee B">B.W. Lee</name></author><author><name sortKey="Nakanishi, K" uniqKey="Nakanishi K">K. Nakanishi</name></author><author><name sortKey="Villasante, A" uniqKey="Villasante A">A. Villasante</name></author><author><name sortKey="Williamson, R" uniqKey="Williamson R">R. Williamson</name></author><author><name sortKey="Metz, J" uniqKey="Metz J">J. Metz</name></author><author><name sortKey="Kim, J" uniqKey="Kim J">J. Kim</name></author><author><name sortKey="Kanai, M" uniqKey="Kanai M">M. Kanai</name></author><author><name sortKey="Bi, L" uniqKey="Bi L">L. Bi</name></author><author><name sortKey="Brown, K" uniqKey="Brown K">K. Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, R C" uniqKey="Lai R">R.C. Lai</name></author><author><name sortKey="Chen, T S" uniqKey="Chen T">T.S. Chen</name></author><author><name sortKey="Lim, S K" uniqKey="Lim S">S.K. Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dougherty, J A" uniqKey="Dougherty J">J.A. Dougherty</name></author><author><name sortKey="Mergaye, M" uniqKey="Mergaye M">M. Mergaye</name></author><author><name sortKey="Kumar, N" uniqKey="Kumar N">N. Kumar</name></author><author><name sortKey="Chen, C A" uniqKey="Chen C">C.-A. Chen</name></author><author><name sortKey="Angelos, M G" uniqKey="Angelos M">M.G. Angelos</name></author><author><name sortKey="Khan, M" uniqKey="Khan M">M. Khan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ibrahim, A G E" uniqKey="Ibrahim A">A.G.-E. Ibrahim</name></author><author><name sortKey="Cheng, K" uniqKey="Cheng K">K. Cheng</name></author><author><name sortKey="Marban, E" uniqKey="Marban E">E. Marbán</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Lim, S K" uniqKey="Lim S">S.K. Lim</name></author><author><name sortKey="Arslan, F" uniqKey="Arslan F">F. Arslan</name></author><author><name sortKey="Armstrong, J S" uniqKey="Armstrong J">J.S. Armstrong</name></author><author><name sortKey="Hoefer, I E" uniqKey="Hoefer I">I.E. Hoefer</name></author><author><name sortKey="Doevendans, P A" uniqKey="Doevendans P">P.A. Doevendans</name></author><author><name sortKey="Piek, J J" uniqKey="Piek J">J.J. Piek</name></author><author><name sortKey="El Oakley, R M" uniqKey="El Oakley R">R.M. El Oakley</name></author><author><name sortKey="Choo, A" uniqKey="Choo A">A. Choo</name></author><author><name sortKey="Lee, C N" uniqKey="Lee C">C.N. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, R C" uniqKey="Lai R">R.C. Lai</name></author><author><name sortKey="Arslan, F" uniqKey="Arslan F">F. Arslan</name></author><author><name sortKey="Lee, M M" uniqKey="Lee M">M.M. Lee</name></author><author><name sortKey="Sze, N S K" uniqKey="Sze N">N.S.K. Sze</name></author><author><name sortKey="Choo, A" uniqKey="Choo A">A. Choo</name></author><author><name sortKey="Chen, T S" uniqKey="Chen T">T.S. Chen</name></author><author><name sortKey="Salto Tellez, M" uniqKey="Salto Tellez M">M. Salto-Tellez</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Lee, C N" uniqKey="Lee C">C.N. Lee</name></author><author><name sortKey="El Oakley, R M" uniqKey="El Oakley R">R.M. El Oakley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, T S" uniqKey="Chen T">T.S. Chen</name></author><author><name sortKey="Lai, R C" uniqKey="Lai R">R.C. Lai</name></author><author><name sortKey="Lee, M M" uniqKey="Lee M">M.M. Lee</name></author><author><name sortKey="Choo, A B H" uniqKey="Choo A">A.B.H. Choo</name></author><author><name sortKey="Lee, C N" uniqKey="Lee C">C.N. Lee</name></author><author><name sortKey="Lim, S K" uniqKey="Lim S">S.K. Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arslan, F" uniqKey="Arslan F">F. Arslan</name></author><author><name sortKey="Lai, R C" uniqKey="Lai R">R.C. Lai</name></author><author><name sortKey="Smeets, M B" uniqKey="Smeets M">M.B. Smeets</name></author><author><name sortKey="Akeroyd, L" uniqKey="Akeroyd L">L. Akeroyd</name></author><author><name sortKey="Choo, A" uniqKey="Choo A">A. Choo</name></author><author><name sortKey="Aguor, E N E" uniqKey="Aguor E">E.N.E. Aguor</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Van Rijen, H V" uniqKey="Van Rijen H">H.V. Van Rijen</name></author><author><name sortKey="Doevendans, P A" uniqKey="Doevendans P">P.A. Doevendans</name></author><author><name sortKey="Pasterkamp, G" uniqKey="Pasterkamp G">G. Pasterkamp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, B" uniqKey="Zhang B">B. Zhang</name></author><author><name sortKey="Yin, Y" uniqKey="Yin Y">Y. Yin</name></author><author><name sortKey="Lai, R C" uniqKey="Lai R">R.C. Lai</name></author><author><name sortKey="Tan, S S" uniqKey="Tan S">S.S. Tan</name></author><author><name sortKey="Choo, A B H" uniqKey="Choo A">A.B.H. Choo</name></author><author><name sortKey="Lim, S K" uniqKey="Lim S">S.K. Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, B" uniqKey="Zhang B">B. Zhang</name></author><author><name sortKey="Yeo, R W Y" uniqKey="Yeo R">R.W.Y. Yeo</name></author><author><name sortKey="Lai, R C" uniqKey="Lai R">R.C. Lai</name></author><author><name sortKey="Sim, E W K" uniqKey="Sim E">E.W.K. Sim</name></author><author><name sortKey="Chin, K C" uniqKey="Chin K">K.C. Chin</name></author><author><name sortKey="Lim, S K" uniqKey="Lim S">S.K. Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Du, Y" uniqKey="Du Y">Y. Du</name></author><author><name sortKey="Zhuansun, Y" uniqKey="Zhuansun Y">Y. Zhuansun</name></author><author><name sortKey="Chen, R" uniqKey="Chen R">R. Chen</name></author><author><name sortKey="Lin, L" uniqKey="Lin L">L. Lin</name></author><author><name sortKey="Lin, Y" uniqKey="Lin Y">Y. Lin</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qiao, L" uniqKey="Qiao L">L. Qiao</name></author><author><name sortKey="Hu, S" uniqKey="Hu S">S. Hu</name></author><author><name sortKey="Liu, S" uniqKey="Liu S">S. Liu</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Ma, H" uniqKey="Ma H">H. Ma</name></author><author><name sortKey="Huang, K" uniqKey="Huang K">K. Huang</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z. Li</name></author><author><name sortKey="Su, T" uniqKey="Su T">T. Su</name></author><author><name sortKey="Vandergriff, A" uniqKey="Vandergriff A">A. Vandergriff</name></author><author><name sortKey="Tang, J" uniqKey="Tang J">J. Tang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Hu, J" uniqKey="Hu J">J. Hu</name></author><author><name sortKey="Chen, F" uniqKey="Chen F">F. Chen</name></author><author><name sortKey="Qiao, S" uniqKey="Qiao S">S. Qiao</name></author><author><name sortKey="Sun, X" uniqKey="Sun X">X. Sun</name></author><author><name sortKey="Gao, L" uniqKey="Gao L">L. Gao</name></author><author><name sortKey="Xie, J" uniqKey="Xie J">J. Xie</name></author><author><name sortKey="Xu, B" uniqKey="Xu B">B. Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gallet, R" uniqKey="Gallet R">R. Gallet</name></author><author><name sortKey="Dawkins, J" uniqKey="Dawkins J">J. Dawkins</name></author><author><name sortKey="Valle, J" uniqKey="Valle J">J. Valle</name></author><author><name sortKey="Simsolo, E" uniqKey="Simsolo E">E. Simsolo</name></author><author><name sortKey="De Couto, G" uniqKey="De Couto G">G. De Couto</name></author><author><name sortKey="Middleton, R" uniqKey="Middleton R">R. Middleton</name></author><author><name sortKey="Tseliou, E" uniqKey="Tseliou E">E. Tseliou</name></author><author><name sortKey="Luthringer, D" uniqKey="Luthringer D">D. Luthringer</name></author><author><name sortKey="Kreke, M" uniqKey="Kreke M">M. Kreke</name></author><author><name sortKey="Smith, R R" uniqKey="Smith R">R.R. Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singla, D K" uniqKey="Singla D">D.K. Singla</name></author><author><name sortKey="Long, X" uniqKey="Long X">X. Long</name></author><author><name sortKey="Glass, C" uniqKey="Glass C">C. Glass</name></author><author><name sortKey="Singla, R D" uniqKey="Singla R">R.D. Singla</name></author><author><name sortKey="Yan, B" uniqKey="Yan B">B. Yan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iglesias Garcia, O" uniqKey="Iglesias Garcia O">O. Iglesias-García</name></author><author><name sortKey="Pelacho, B" uniqKey="Pelacho B">B. Pelacho</name></author><author><name sortKey="Pr Sper, F" uniqKey="Pr Sper F">F. Prósper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamakawa, H" uniqKey="Yamakawa H">H. Yamakawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Chen, L" uniqKey="Chen L">L. Chen</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Guo, W" uniqKey="Guo W">W. Guo</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X. Zhang</name></author><author><name sortKey="Qin, G" uniqKey="Qin G">G. Qin</name></author><author><name sortKey="He, S" uniqKey="He S">S. He</name></author><author><name sortKey="Zimmerman, A" uniqKey="Zimmerman A">A. Zimmerman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bobis Wozowicz, S" uniqKey="Bobis Wozowicz S">S. Bobis-Wozowicz</name></author><author><name sortKey="Kmiotek, K" uniqKey="Kmiotek K">K. Kmiotek</name></author><author><name sortKey="Sekula, M" uniqKey="Sekula M">M. Sekula</name></author><author><name sortKey="Kedracka Krok, S" uniqKey="Kedracka Krok S">S. Kedracka-Krok</name></author><author><name sortKey="Kamycka, E" uniqKey="Kamycka E">E. Kamycka</name></author><author><name sortKey="Adamiak, M" uniqKey="Adamiak M">M. Adamiak</name></author><author><name sortKey="Jankowska, U" uniqKey="Jankowska U">U. Jankowska</name></author><author><name sortKey="Madetko Talowska, A" uniqKey="Madetko Talowska A">A. Madetko-Talowska</name></author><author><name sortKey="Sarna, M" uniqKey="Sarna M">M. Sarna</name></author><author><name sortKey="Bik Multanowski, M" uniqKey="Bik Multanowski M">M. Bik-Multanowski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gupta, S" uniqKey="Gupta S">S. Gupta</name></author><author><name sortKey="Knowlton, A A" uniqKey="Knowlton A">A.A. Knowlton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pironti, G" uniqKey="Pironti G">G. Pironti</name></author><author><name sortKey="Strachan, R T" uniqKey="Strachan R">R.T. Strachan</name></author><author><name sortKey="Abraham, D" uniqKey="Abraham D">D. Abraham</name></author><author><name sortKey="Mon Wei Yu, S" uniqKey="Mon Wei Yu S">S. Mon-Wei Yu</name></author><author><name sortKey="Chen, M" uniqKey="Chen M">M. Chen</name></author><author><name sortKey="Chen, W" uniqKey="Chen W">W. Chen</name></author><author><name sortKey="Hanada, K" uniqKey="Hanada K">K. Hanada</name></author><author><name sortKey="Mao, L" uniqKey="Mao L">L. Mao</name></author><author><name sortKey="Watson, L J" uniqKey="Watson L">L.J. Watson</name></author><author><name sortKey="Rockman, H A" uniqKey="Rockman H">H.A. Rockman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, X" uniqKey="Yu X">X. Yu</name></author><author><name sortKey="Deng, L" uniqKey="Deng L">L. Deng</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Li, N" uniqKey="Li N">N. Li</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Cheng, X" uniqKey="Cheng X">X. Cheng</name></author><author><name sortKey="Yuan, J" uniqKey="Yuan J">J. Yuan</name></author><author><name sortKey="Gao, X" uniqKey="Gao X">X. Gao</name></author><author><name sortKey="Liao, M" uniqKey="Liao M">M. Liao</name></author><author><name sortKey="Wang, M" uniqKey="Wang M">M. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Peng, T" uniqKey="Peng T">T. Peng</name></author><author><name sortKey="Huang, W" uniqKey="Huang W">W. Huang</name></author><author><name sortKey="Millard, R W" uniqKey="Millard R">R.W. Millard</name></author><author><name sortKey="Liu, G" uniqKey="Liu G">G. Liu</name></author><author><name sortKey="Chang, J" uniqKey="Chang J">J. Chang</name></author><author><name sortKey="Cai, W" uniqKey="Cai W">W. Cai</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Fan, G C" uniqKey="Fan G">G.-C. Fan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arslan, F" uniqKey="Arslan F">F. Arslan</name></author><author><name sortKey="Smeets, M B" uniqKey="Smeets M">M.B. Smeets</name></author><author><name sortKey="O Eill, L A J" uniqKey="O Eill L">L.A.J. O’Neill</name></author><author><name sortKey="Keogh, B" uniqKey="Keogh B">B. Keogh</name></author><author><name sortKey="Mcguirk, P" uniqKey="Mcguirk P">P. McGuirk</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author><author><name sortKey="Tersteeg, C" uniqKey="Tersteeg C">C. Tersteeg</name></author><author><name sortKey="Hoefer, I E" uniqKey="Hoefer I">I.E. Hoefer</name></author><author><name sortKey="Doevendans, P A" uniqKey="Doevendans P">P.A. Doevendans</name></author><author><name sortKey="Pasterkamp, G" uniqKey="Pasterkamp G">G. Pasterkamp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, J W" uniqKey="Wang J">J.-W. Wang</name></author><author><name sortKey="Fontes, M S C" uniqKey="Fontes M">M.S.C. Fontes</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Chong, S Y" uniqKey="Chong S">S.Y. Chong</name></author><author><name sortKey="Kessler, E L" uniqKey="Kessler E">E.L. Kessler</name></author><author><name sortKey="Zhang, Y N" uniqKey="Zhang Y">Y.-N. Zhang</name></author><author><name sortKey="De Haan, J J" uniqKey="De Haan J">J.J. De Haan</name></author><author><name sortKey="Arslan, F" uniqKey="Arslan F">F. Arslan</name></author><author><name sortKey="De Jager, S C A" uniqKey="De Jager S">S.C.A. De Jager</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bonaventura, A" uniqKey="Bonaventura A">A. Bonaventura</name></author><author><name sortKey="Montecucco, F" uniqKey="Montecucco F">F. Montecucco</name></author><author><name sortKey="Dallegri, F" uniqKey="Dallegri F">F. Dallegri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Kleijn, D P V" uniqKey="De Kleijn D">D.P.V. De Kleijn</name></author><author><name sortKey="Chong, S Y" uniqKey="Chong S">S.Y. Chong</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Yatim, S M J M" uniqKey="Yatim S">S.M.J.M. Yatim</name></author><author><name sortKey="Fairhurst, A M" uniqKey="Fairhurst A">A.-M. Fairhurst</name></author><author><name sortKey="Vernooij, F" uniqKey="Vernooij F">F. Vernooij</name></author><author><name sortKey="Zharkova, O" uniqKey="Zharkova O">O. Zharkova</name></author><author><name sortKey="Chan, M Y" uniqKey="Chan M">M.Y. Chan</name></author><author><name sortKey="Foo, R S Y" uniqKey="Foo R">R.S.Y. Foo</name></author><author><name sortKey="Timmers, L" uniqKey="Timmers L">L. Timmers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Gu, H" uniqKey="Gu H">H. Gu</name></author><author><name sortKey="Huang, W" uniqKey="Huang W">W. Huang</name></author><author><name sortKey="Peng, J" uniqKey="Peng J">J. Peng</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author><author><name sortKey="Qin, D" uniqKey="Qin D">D. Qin</name></author><author><name sortKey="Essandoh, K" uniqKey="Essandoh K">K. Essandoh</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Peng, T" uniqKey="Peng T">T. Peng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vrijsen, K R" uniqKey="Vrijsen K">K.R. Vrijsen</name></author><author><name sortKey="Sluijter, J P G" uniqKey="Sluijter J">J.P.G. Sluijter</name></author><author><name sortKey="Schuchardt, M W L" uniqKey="Schuchardt M">M.W.L. Schuchardt</name></author><author><name sortKey="Van Balkom, B W" uniqKey="Van Balkom B">B.W. Van Balkom</name></author><author><name sortKey="Noort, W A" uniqKey="Noort W">W.A. Noort</name></author><author><name sortKey="Chamuleau, S A J" uniqKey="Chamuleau S">S.A.J. Chamuleau</name></author><author><name sortKey="Doevendans, P A F" uniqKey="Doevendans P">P.A.F. Doevendans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gray, W D" uniqKey="Gray W">W.D. Gray</name></author><author><name sortKey="French, K M" uniqKey="French K">K.M. French</name></author><author><name sortKey="Ghosh Choudhary, S" uniqKey="Ghosh Choudhary S">S. Ghosh-Choudhary</name></author><author><name sortKey="Maxwell, J T" uniqKey="Maxwell J">J.T. Maxwell</name></author><author><name sortKey="Brown, M E" uniqKey="Brown M">M.E. Brown</name></author><author><name sortKey="Platt, M O" uniqKey="Platt M">M.O. Platt</name></author><author><name sortKey="Searles, C D" uniqKey="Searles C">C.D. Searles</name></author><author><name sortKey="Davis, M E" uniqKey="Davis M">M.E. Davis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barile, L" uniqKey="Barile L">L. Barile</name></author><author><name sortKey="Lionetti, V" uniqKey="Lionetti V">V. Lionetti</name></author><author><name sortKey="Cervio, E" uniqKey="Cervio E">E. Cervio</name></author><author><name sortKey="Matteucci, M" uniqKey="Matteucci M">M. Matteucci</name></author><author><name sortKey="Gherghiceanu, M" uniqKey="Gherghiceanu M">M. Gherghiceanu</name></author><author><name sortKey="Popescu, L M" uniqKey="Popescu L">L.M. Popescu</name></author><author><name sortKey="Torre, T" uniqKey="Torre T">T. Torre</name></author><author><name sortKey="Siclari, F" uniqKey="Siclari F">F. Siclari</name></author><author><name sortKey="Moccetti, T" uniqKey="Moccetti T">T. Moccetti</name></author><author><name sortKey="Vassalli, G" uniqKey="Vassalli G">G. Vassalli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agarwal, U" uniqKey="Agarwal U">U. Agarwal</name></author><author><name sortKey="George, A" uniqKey="George A">A. George</name></author><author><name sortKey="Bhutani, S" uniqKey="Bhutani S">S. Bhutani</name></author><author><name sortKey="Ghosh Choudhary, S" uniqKey="Ghosh Choudhary S">S. Ghosh-Choudhary</name></author><author><name sortKey="Maxwell, J T" uniqKey="Maxwell J">J.T. Maxwell</name></author><author><name sortKey="Brown, M E" uniqKey="Brown M">M.E. Brown</name></author><author><name sortKey="Mehta, Y" uniqKey="Mehta Y">Y. Mehta</name></author><author><name sortKey="Platt, M O" uniqKey="Platt M">M.O. Platt</name></author><author><name sortKey="Liang, Y" uniqKey="Liang Y">Y. Liang</name></author><author><name sortKey="Sahoo, S" uniqKey="Sahoo S">S. Sahoo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maring, J A" uniqKey="Maring J">J.A. Maring</name></author><author><name sortKey="Lodder, K" uniqKey="Lodder K">K. Lodder</name></author><author><name sortKey="Mol, E" uniqKey="Mol E">E. Mol</name></author><author><name sortKey="Verhage, V" uniqKey="Verhage V">V. Verhage</name></author><author><name sortKey="Wiesmeijer, K C" uniqKey="Wiesmeijer K">K.C. Wiesmeijer</name></author><author><name sortKey="Dingenouts, C K E" uniqKey="Dingenouts C">C.K.E. Dingenouts</name></author><author><name sortKey="Moerkamp, A T" uniqKey="Moerkamp A">A.T. Moerkamp</name></author><author><name sortKey="Deddens, J C" uniqKey="Deddens J">J.C. Deddens</name></author><author><name sortKey="Vader, P" uniqKey="Vader P">P. Vader</name></author><author><name sortKey="Smits, A M" uniqKey="Smits A">A.M. Smits</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuana, Y" uniqKey="Yuana Y">Y. Yuana</name></author><author><name sortKey="Jiang, L" uniqKey="Jiang L">L. Jiang</name></author><author><name sortKey="Lammertink, B" uniqKey="Lammertink B">B. Lammertink</name></author><author><name sortKey="Vader, P" uniqKey="Vader P">P. Vader</name></author><author><name sortKey="Deckers, R" uniqKey="Deckers R">R. Deckers</name></author><author><name sortKey="Bos, C" uniqKey="Bos C">C. Bos</name></author><author><name sortKey="Schiffelers, R" uniqKey="Schiffelers R">R. Schiffelers</name></author><author><name sortKey="Moonen, C" uniqKey="Moonen C">C. Moonen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Olson, E N" uniqKey="Olson E">E.N. Olson</name></author><author><name sortKey="Hristov, M" uniqKey="Hristov M">M. Hristov</name></author><author><name sortKey="Jahantigh, M N" uniqKey="Jahantigh M">M.N. Jahantigh</name></author><author><name sortKey="Weber, C" uniqKey="Weber C">C. Weber</name></author><author><name sortKey="Shagdarsuren, E" uniqKey="Shagdarsuren E">E. Shagdarsuren</name></author><author><name sortKey="Zernecke, A" uniqKey="Zernecke A">A. Zernecke</name></author><author><name sortKey="Lutgens, E" uniqKey="Lutgens E">E. Lutgens</name></author><author><name sortKey="Bidzhekov, K" uniqKey="Bidzhekov K">K. Bidzhekov</name></author><author><name sortKey="Gan, L" uniqKey="Gan L">L. Gan</name></author><author><name sortKey="Koppel, T" uniqKey="Koppel T">T. Koppel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Balkom, B W M" uniqKey="Van Balkom B">B.W.M. Van Balkom</name></author><author><name sortKey="De Jong, O G" uniqKey="De Jong O">O.G. De Jong</name></author><author><name sortKey="Smits, M" uniqKey="Smits M">M. Smits</name></author><author><name sortKey="Brummelman, J" uniqKey="Brummelman J">J. Brummelman</name></author><author><name sortKey="Den Ouden, K" uniqKey="Den Ouden K">K. Den Ouden</name></author><author><name sortKey="De Bree, P M" uniqKey="De Bree P">P.M. De Bree</name></author><author><name sortKey="Van Eijndhoven, M A J" uniqKey="Van Eijndhoven M">M.A.J. Van Eijndhoven</name></author><author><name sortKey="Pegtel, D M" uniqKey="Pegtel D">D.M. Pegtel</name></author><author><name sortKey="Stoorvogel, W" uniqKey="Stoorvogel W">W. Stoorvogel</name></author><author><name sortKey="Wurdinger, T" uniqKey="Wurdinger T">T. Wurdinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brill, A" uniqKey="Brill A">A. Brill</name></author><author><name sortKey="Dashevsky, O" uniqKey="Dashevsky O">O. Dashevsky</name></author><author><name sortKey="Rivo, J" uniqKey="Rivo J">J. Rivo</name></author><author><name sortKey="Gozal, Y" uniqKey="Gozal Y">Y. Gozal</name></author><author><name sortKey="Varon, D" uniqKey="Varon D">D. Varon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Badimon, L" uniqKey="Badimon L">L. Badimon</name></author><author><name sortKey="Suades, R" uniqKey="Suades R">R. Suades</name></author><author><name sortKey="Fuentes, E" uniqKey="Fuentes E">E. Fuentes</name></author><author><name sortKey="Palomo, I" uniqKey="Palomo I">I. Palomo</name></author><author><name sortKey="Padr, T" uniqKey="Padr T">T. Padró</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lyu, L" uniqKey="Lyu L">L. Lyu</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H. Wang</name></author><author><name sortKey="Li, B" uniqKey="Li B">B. Li</name></author><author><name sortKey="Qin, Q" uniqKey="Qin Q">Q. Qin</name></author><author><name sortKey="Qi, L" uniqKey="Qi L">L. Qi</name></author><author><name sortKey="Nagarkatti, M" uniqKey="Nagarkatti M">M. Nagarkatti</name></author><author><name sortKey="Nagarkatti, P" uniqKey="Nagarkatti P">P. Nagarkatti</name></author><author><name sortKey="Janicki, J S" uniqKey="Janicki J">J.S. Janicki</name></author><author><name sortKey="Wang, X L" uniqKey="Wang X">X.L. Wang</name></author><author><name sortKey="Cui, T" uniqKey="Cui T">T. Cui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kapustin, A N" uniqKey="Kapustin A">A.N. Kapustin</name></author><author><name sortKey="Chatrou, M L L" uniqKey="Chatrou M">M.L.L. Chatrou</name></author><author><name sortKey="Drozdov, I" uniqKey="Drozdov I">I. Drozdov</name></author><author><name sortKey="Zheng, Y" uniqKey="Zheng Y">Y. Zheng</name></author><author><name sortKey="Davidson, S M" uniqKey="Davidson S">S.M. Davidson</name></author><author><name sortKey="Soong, D" uniqKey="Soong D">D. Soong</name></author><author><name sortKey="Furmanik, M" uniqKey="Furmanik M">M. Furmanik</name></author><author><name sortKey="Sanchis, P" uniqKey="Sanchis P">P. Sanchis</name></author><author><name sortKey="De Rosales, R T M" uniqKey="De Rosales R">R.T.M. De Rosales</name></author><author><name sortKey="Alvarez Hernandez, D" uniqKey="Alvarez Hernandez D">D. Alvarez-Hernandez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wen, C" uniqKey="Wen C">C. Wen</name></author><author><name sortKey="Seeger, R C" uniqKey="Seeger R">R.C. Seeger</name></author><author><name sortKey="Fabbri, M" uniqKey="Fabbri M">M. Fabbri</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Wayne, A S" uniqKey="Wayne A">A.S. Wayne</name></author><author><name sortKey="Jong, A Y" uniqKey="Jong A">A.Y. Jong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Veerman, R E" uniqKey="Veerman R">R.E. Veerman</name></author><author><name sortKey="Gucluler Akpinar, G" uniqKey="Gucluler Akpinar G">G. Güçlüler Akpinar</name></author><author><name sortKey="Eldh, M" uniqKey="Eldh M">M. Eldh</name></author><author><name sortKey="Gabrielsson, S" uniqKey="Gabrielsson S">S. Gabrielsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vicencio, J M" uniqKey="Vicencio J">J.M. Vicencio</name></author><author><name sortKey="Yellon, D M" uniqKey="Yellon D">D.M. Yellon</name></author><author><name sortKey="Sivaraman, V" uniqKey="Sivaraman V">V. Sivaraman</name></author><author><name sortKey="Das, D" uniqKey="Das D">D. Das</name></author><author><name sortKey="Boi Doku, C" uniqKey="Boi Doku C">C. Boi-Doku</name></author><author><name sortKey="Arjun, S" uniqKey="Arjun S">S. Arjun</name></author><author><name sortKey="Zheng, Y" uniqKey="Zheng Y">Y. Zheng</name></author><author><name sortKey="Riquelme, J A" uniqKey="Riquelme J">J.A. Riquelme</name></author><author><name sortKey="Kearney, J" uniqKey="Kearney J">J. Kearney</name></author><author><name sortKey="Sharma, V" uniqKey="Sharma V">V. Sharma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bassyouni, F" uniqKey="Bassyouni F">F. Bassyouni</name></author><author><name sortKey="Elhalwany, N" uniqKey="Elhalwany N">N. ElHalwany</name></author><author><name sortKey="Abdel Rehim, M" uniqKey="Abdel Rehim M">M. Abdel Rehim</name></author><author><name sortKey="Neyfeh, M" uniqKey="Neyfeh M">M. Neyfeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tiwari, G" uniqKey="Tiwari G">G. Tiwari</name></author><author><name sortKey="Tiwari, R" uniqKey="Tiwari R">R. Tiwari</name></author><author><name sortKey="Sriwastawa, B" uniqKey="Sriwastawa B">B. Sriwastawa</name></author><author><name sortKey="Bhati, L" uniqKey="Bhati L">L. Bhati</name></author><author><name sortKey="Pandey, S" uniqKey="Pandey S">S. Pandey</name></author><author><name sortKey="Pandey, P" uniqKey="Pandey P">P. Pandey</name></author><author><name sortKey="Bannerjee, S K" uniqKey="Bannerjee S">S.K. Bannerjee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bunker, A" uniqKey="Bunker A">A. Bunker</name></author><author><name sortKey="Magarkar, A" uniqKey="Magarkar A">A. Magarkar</name></author><author><name sortKey="Viitala, T" uniqKey="Viitala T">T. Viitala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scott, R C" uniqKey="Scott R">R.C. Scott</name></author><author><name sortKey="Crabbe, D" uniqKey="Crabbe D">D. Crabbe</name></author><author><name sortKey="Krynska, B" uniqKey="Krynska B">B. Krynska</name></author><author><name sortKey="Ansari, R" uniqKey="Ansari R">R. Ansari</name></author><author><name sortKey="Kiani, M F" uniqKey="Kiani M">M.F. Kiani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fancher, I S" uniqKey="Fancher I">I.S. Fancher</name></author><author><name sortKey="Rubinstein, I" uniqKey="Rubinstein I">I. Rubinstein</name></author><author><name sortKey="Levitan, I" uniqKey="Levitan I">I. Levitan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bowey, K" uniqKey="Bowey K">K. Bowey</name></author><author><name sortKey="Tanguay, J F" uniqKey="Tanguay J">J.-F. Tanguay</name></author><author><name sortKey="Tabrizian, M" uniqKey="Tabrizian M">M. Tabrizian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dvir, T" uniqKey="Dvir T">T. Dvir</name></author><author><name sortKey="Bauer, M" uniqKey="Bauer M">M. Bauer</name></author><author><name sortKey="Schroeder, A" uniqKey="Schroeder A">A. Schroeder</name></author><author><name sortKey="Tsui, J H" uniqKey="Tsui J">J.H. Tsui</name></author><author><name sortKey="Anderson, D G" uniqKey="Anderson D">D.G. Anderson</name></author><author><name sortKey="Langer, R" uniqKey="Langer R">R. Langer</name></author><author><name sortKey="Liao, R" uniqKey="Liao R">R. Liao</name></author><author><name sortKey="Kohane, D S" uniqKey="Kohane D">D.S. Kohane</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allijn, I E" uniqKey="Allijn I">I.E. Allijn</name></author><author><name sortKey="Czarny, B M S" uniqKey="Czarny B">B.M.S. Czarny</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Chong, S Y" uniqKey="Chong S">S.Y. Chong</name></author><author><name sortKey="Weiler, M" uniqKey="Weiler M">M. Weiler</name></author><author><name sortKey="Da Silva, A E" uniqKey="Da Silva A">A.E. Da Silva</name></author><author><name sortKey="Metselaar, J M" uniqKey="Metselaar J">J.M. Metselaar</name></author><author><name sortKey="Lam, C S P" uniqKey="Lam C">C.S.P. Lam</name></author><author><name sortKey="Pastorin, G" uniqKey="Pastorin G">G. Pastorin</name></author><author><name sortKey="De Kleijn, D P V" uniqKey="De Kleijn D">D.P.V. De Kleijn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goh, W J" uniqKey="Goh W">W.J. Goh</name></author><author><name sortKey="Zou, S" uniqKey="Zou S">S. Zou</name></author><author><name sortKey="Czarny, B" uniqKey="Czarny B">B. Czarny</name></author><author><name sortKey="Pastorin, G" uniqKey="Pastorin G">G. Pastorin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goh, W J" uniqKey="Goh W">W.J. Goh</name></author><author><name sortKey="Zou, S" uniqKey="Zou S">S. Zou</name></author><author><name sortKey="Lee, C K" uniqKey="Lee C">C.K. Lee</name></author><author><name sortKey="Ou, Y H" uniqKey="Ou Y">Y.-H. Ou</name></author><author><name sortKey="Wang, J W" uniqKey="Wang J">J.-W. Wang</name></author><author><name sortKey="Czarny, B" uniqKey="Czarny B">B. Czarny</name></author><author><name sortKey="Pastorin, G" uniqKey="Pastorin G">G. Pastorin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fuhrmann, G" uniqKey="Fuhrmann G">G. Fuhrmann</name></author><author><name sortKey="Herrmann, I K" uniqKey="Herrmann I">I.K. Herrmann</name></author><author><name sortKey="Stevens, M M" uniqKey="Stevens M">M.M. Stevens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yurkin, S T" uniqKey="Yurkin S">S.T. Yurkin</name></author><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Imai, T" uniqKey="Imai T">T. Imai</name></author><author><name sortKey="Takahashi, Y" uniqKey="Takahashi Y">Y. Takahashi</name></author><author><name sortKey="Nishikawa, M" uniqKey="Nishikawa M">M. Nishikawa</name></author><author><name sortKey="Kato, K" uniqKey="Kato K">K. Kato</name></author><author><name sortKey="Morishita, M" uniqKey="Morishita M">M. Morishita</name></author><author><name sortKey="Yamashita, T" uniqKey="Yamashita T">T. Yamashita</name></author><author><name sortKey="Matsumoto, A" uniqKey="Matsumoto A">A. Matsumoto</name></author><author><name sortKey="Charoenviriyakul, C" uniqKey="Charoenviriyakul C">C. Charoenviriyakul</name></author><author><name sortKey="Takakura, Y" uniqKey="Takakura Y">Y. Takakura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolfram, J" uniqKey="Wolfram J">J. Wolfram</name></author><author><name sortKey="Nizzero, S" uniqKey="Nizzero S">S. Nizzero</name></author><author><name sortKey="Liu, H" uniqKey="Liu H">H. Liu</name></author><author><name sortKey="Li, F" uniqKey="Li F">F. Li</name></author><author><name sortKey="Zhang, G" uniqKey="Zhang G">G. Zhang</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z. Li</name></author><author><name sortKey="Shen, H" uniqKey="Shen H">H. Shen</name></author><author><name sortKey="Blanco, E" uniqKey="Blanco E">E. Blanco</name></author><author><name sortKey="Ferrari, M" uniqKey="Ferrari M">M. Ferrari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vandergriff, A" uniqKey="Vandergriff A">A. Vandergriff</name></author><author><name sortKey="Huang, K" uniqKey="Huang K">K. Huang</name></author><author><name sortKey="Shen, D" uniqKey="Shen D">D. Shen</name></author><author><name sortKey="Hu, S" uniqKey="Hu S">S. Hu</name></author><author><name sortKey="Hensley, M T" uniqKey="Hensley M">M.T. Hensley</name></author><author><name sortKey="Caranasos, T G" uniqKey="Caranasos T">T.G. Caranasos</name></author><author><name sortKey="Qian, L" uniqKey="Qian L">L. Qian</name></author><author><name sortKey="Cheng, K" uniqKey="Cheng K">K. Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, H" uniqKey="Kim H">H. Kim</name></author><author><name sortKey="Yun, N" uniqKey="Yun N">N. Yun</name></author><author><name sortKey="Mun, D" uniqKey="Mun D">D. Mun</name></author><author><name sortKey="Kang, J Y" uniqKey="Kang J">J.-Y. Kang</name></author><author><name sortKey="Lee, S H" uniqKey="Lee S">S.-H. Lee</name></author><author><name sortKey="Park, H" uniqKey="Park H">H. Park</name></author><author><name sortKey="Park, H" uniqKey="Park H">H. Park</name></author><author><name sortKey="Joung, B" uniqKey="Joung B">B. Joung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y. Chen</name></author><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Meng, Q" uniqKey="Meng Q">Q. Meng</name></author><author><name sortKey="Yu, Y" uniqKey="Yu Y">Y. Yu</name></author><author><name sortKey="Sun, J" uniqKey="Sun J">J. Sun</name></author><author><name sortKey="Yang, Z" uniqKey="Yang Z">Z. Yang</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y. Chen</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Ma, T" uniqKey="Ma T">T. Ma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Davis, B M" uniqKey="Davis B">B.M. Davis</name></author><author><name sortKey="Pahlitzsch, M" uniqKey="Pahlitzsch M">M. Pahlitzsch</name></author><author><name sortKey="Guo, L" uniqKey="Guo L">L. Guo</name></author><author><name sortKey="Balendra, S" uniqKey="Balendra S">S. Balendra</name></author><author><name sortKey="Shah, P" uniqKey="Shah P">P. Shah</name></author><author><name sortKey="Ravindran, N" uniqKey="Ravindran N">N. Ravindran</name></author><author><name sortKey="Malaguarnera, G" uniqKey="Malaguarnera G">G. Malaguarnera</name></author><author><name sortKey="Sisa, C" uniqKey="Sisa C">C. Sisa</name></author><author><name sortKey="Shamsher, E" uniqKey="Shamsher E">E. Shamsher</name></author><author><name sortKey="Hamze, H" uniqKey="Hamze H">H. Hamze</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tian, T" uniqKey="Tian T">T. Tian</name></author><author><name sortKey="Zhang, H X" uniqKey="Zhang H">H.X. Zhang</name></author><author><name sortKey="He, C P" uniqKey="He C">C.P. He</name></author><author><name sortKey="Fan, S" uniqKey="Fan S">S. Fan</name></author><author><name sortKey="Zhu, Y L" uniqKey="Zhu Y">Y.L. Zhu</name></author><author><name sortKey="Qi, C" uniqKey="Qi C">C. Qi</name></author><author><name sortKey="Huang, N P" uniqKey="Huang N">N.P. Huang</name></author><author><name sortKey="Xiao, Z D" uniqKey="Xiao Z">Z.D. Xiao</name></author><author><name sortKey="Lu, Z H" uniqKey="Lu Z">Z.H. Lu</name></author><author><name sortKey="Tannous, B A" uniqKey="Tannous B">B.A. Tannous</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Fan, Q" uniqKey="Fan Q">Q. Fan</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J. Zhou</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J. Wu</name></author><author><name sortKey="Liu, S" uniqKey="Liu S">S. Liu</name></author><author><name sortKey="Zang, J" uniqKey="Zang J">J. Zang</name></author><author><name sortKey="Ye, J" uniqKey="Ye J">J. Ye</name></author><author><name sortKey="Xiao, M" uniqKey="Xiao M">M. Xiao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Naghavi, M" uniqKey="Naghavi M">M. Naghavi</name></author><author><name sortKey="Libby, P" uniqKey="Libby P">P. Libby</name></author><author><name sortKey="Falk, E" uniqKey="Falk E">E. Falk</name></author><author><name sortKey="Casscells, S W" uniqKey="Casscells S">S.W. Casscells</name></author><author><name sortKey="Litovsky, S" uniqKey="Litovsky S">S. Litovsky</name></author><author><name sortKey="Rumberger, J" uniqKey="Rumberger J">J. Rumberger</name></author><author><name sortKey="Badimon, J J" uniqKey="Badimon J">J.J. Badimon</name></author><author><name sortKey="Stefanadis, C" uniqKey="Stefanadis C">C. Stefanadis</name></author><author><name sortKey="Moreno, P" uniqKey="Moreno P">P. Moreno</name></author><author><name sortKey="Pasterkamp, G" uniqKey="Pasterkamp G">G. Pasterkamp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lobatto, M E" uniqKey="Lobatto M">M.E. Lobatto</name></author><author><name sortKey="Fuster, V" uniqKey="Fuster V">V. Fuster</name></author><author><name sortKey="Fayad, Z A" uniqKey="Fayad Z">Z.A. Fayad</name></author><author><name sortKey="Mulder, W J M" uniqKey="Mulder W">W.J.M. Mulder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dobrovolskaia, M A" uniqKey="Dobrovolskaia M">M.A. Dobrovolskaia</name></author><author><name sortKey="Mcneil, S E" uniqKey="Mcneil S">S.E. McNeil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="He, J" uniqKey="He J">J. He</name></author><author><name sortKey="Banizs, A" uniqKey="Banizs A">A. Banizs</name></author><author><name sortKey="Huang, T" uniqKey="Huang T">T. Huang</name></author><author><name sortKey="Dryden, K" uniqKey="Dryden K">K. Dryden</name></author><author><name sortKey="Berr, S" uniqKey="Berr S">S. Berr</name></author><author><name sortKey="Stone, J" uniqKey="Stone J">J. Stone</name></author><author><name sortKey="Nakamoto, R" uniqKey="Nakamoto R">R. Nakamoto</name></author><author><name sortKey="Shi, W" uniqKey="Shi W">W. Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hergenreider, E" uniqKey="Hergenreider E">E. Hergenreider</name></author><author><name sortKey="Heydt, S" uniqKey="Heydt S">S. Heydt</name></author><author><name sortKey="Treguer, K" uniqKey="Treguer K">K. Tréguer</name></author><author><name sortKey="Boettger, T" uniqKey="Boettger T">T. Boettger</name></author><author><name sortKey="Horrevoets, A J G" uniqKey="Horrevoets A">A.J.G. Horrevoets</name></author><author><name sortKey="Zeiher, A M" uniqKey="Zeiher A">A.M. Zeiher</name></author><author><name sortKey="Scheffer, M P" uniqKey="Scheffer M">M.P. Scheffer</name></author><author><name sortKey="Frangakis, A S" uniqKey="Frangakis A">A.S. Frangakis</name></author><author><name sortKey="Yin, X" uniqKey="Yin X">X. Yin</name></author><author><name sortKey="Mayr, M" uniqKey="Mayr M">M. Mayr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jansen, F" uniqKey="Jansen F">F. Jansen</name></author><author><name sortKey="Yang, X" uniqKey="Yang X">X. Yang</name></author><author><name sortKey="Hoelscher, M" uniqKey="Hoelscher M">M. Hoelscher</name></author><author><name sortKey="Cattelan, A" uniqKey="Cattelan A">A. Cattelan</name></author><author><name sortKey="Schmitz, T" uniqKey="Schmitz T">T. Schmitz</name></author><author><name sortKey="Proebsting, S" uniqKey="Proebsting S">S. Proebsting</name></author><author><name sortKey="Wenzel, D" uniqKey="Wenzel D">D. Wenzel</name></author><author><name sortKey="Vosen, S" uniqKey="Vosen S">S. Vosen</name></author><author><name sortKey="Franklin, B S" uniqKey="Franklin B">B.S. Franklin</name></author><author><name sortKey="Fleischmann, B K" uniqKey="Fleischmann B">B.K. Fleischmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Afergan, E" uniqKey="Afergan E">E. Afergan</name></author><author><name sortKey="Ben David, M" uniqKey="Ben David M">M. Ben David</name></author><author><name sortKey="Epstein, H" uniqKey="Epstein H">H. Epstein</name></author><author><name sortKey="Koroukhov, N" uniqKey="Koroukhov N">N. Koroukhov</name></author><author><name sortKey="Gilhar, D" uniqKey="Gilhar D">D. Gilhar</name></author><author><name sortKey="Rohekar, K" uniqKey="Rohekar K">K. Rohekar</name></author><author><name sortKey="Danenberg, H D" uniqKey="Danenberg H">H.D. Danenberg</name></author><author><name sortKey="Golomb, G" uniqKey="Golomb G">G. Golomb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haber, E" uniqKey="Haber E">E. Haber</name></author><author><name sortKey="Afergan, E" uniqKey="Afergan E">E. Afergan</name></author><author><name sortKey="Epstein, H" uniqKey="Epstein H">H. Epstein</name></author><author><name sortKey="Gutman, D" uniqKey="Gutman D">D. Gutman</name></author><author><name sortKey="Koroukhov, N" uniqKey="Koroukhov N">N. Koroukhov</name></author><author><name sortKey="Ben David, M" uniqKey="Ben David M">M. Ben-David</name></author><author><name sortKey="Schachter, M" uniqKey="Schachter M">M. Schachter</name></author><author><name sortKey="Golomb, G" uniqKey="Golomb G">G. Golomb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, S L" uniqKey="Huang S">S.-L. Huang</name></author><author><name sortKey="Kee, P H" uniqKey="Kee P">P.H. Kee</name></author><author><name sortKey="Kim, H" uniqKey="Kim H">H. Kim</name></author><author><name sortKey="Moody, M R" uniqKey="Moody M">M.R. Moody</name></author><author><name sortKey="Chrzanowski, S M" uniqKey="Chrzanowski S">S.M. Chrzanowski</name></author><author><name sortKey="Macdonald, R C" uniqKey="Macdonald R">R.C. MacDonald</name></author><author><name sortKey="Mcpherson, D D" uniqKey="Mcpherson D">D.D. McPherson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scott, R C" uniqKey="Scott R">R.C. Scott</name></author><author><name sortKey="Rosano, J M" uniqKey="Rosano J">J.M. Rosano</name></author><author><name sortKey="Ivanov, Z" uniqKey="Ivanov Z">Z. Ivanov</name></author><author><name sortKey="Wang, B" uniqKey="Wang B">B. Wang</name></author><author><name sortKey="Chong, P L G" uniqKey="Chong P">P.L.-G. Chong</name></author><author><name sortKey="Issekutz, A C" uniqKey="Issekutz A">A.C. Issekutz</name></author><author><name sortKey="Crabbe, D L" uniqKey="Crabbe D">D.L. Crabbe</name></author><author><name sortKey="Kiani, M F" uniqKey="Kiani M">M.F. Kiani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Bittencourt, P I H" uniqKey="De Bittencourt P">P.I.H. De Bittencourt</name></author><author><name sortKey="Lagranha, D J" uniqKey="Lagranha D">D.J. Lagranha</name></author><author><name sortKey="Maslinkiewicz, A" uniqKey="Maslinkiewicz A">A. Maslinkiewicz</name></author><author><name sortKey="Senna, S M" uniqKey="Senna S">S.M. Senna</name></author><author><name sortKey="Tavares, A M V" uniqKey="Tavares A">A.M.V. Tavares</name></author><author><name sortKey="Baldissera, L P" uniqKey="Baldissera L">L.P. Baldissera</name></author><author><name sortKey="Janner, D R" uniqKey="Janner D">D.R. Janner</name></author><author><name sortKey="Peralta, J S" uniqKey="Peralta J">J.S. Peralta</name></author><author><name sortKey="Bock, P M" uniqKey="Bock P">P.M. Bock</name></author><author><name sortKey="Gutierrez, L L P" uniqKey="Gutierrez L">L.L.P. Gutierrez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pont, I" uniqKey="Pont I">I. Pont</name></author><author><name sortKey="Calatayud Pascual, A" uniqKey="Calatayud Pascual A">A. Calatayud-Pascual</name></author><author><name sortKey="L Pez Castellano, A" uniqKey="L Pez Castellano A">A. López-Castellano</name></author><author><name sortKey="Albelda, E P" uniqKey="Albelda E">E.P. Albelda</name></author><author><name sortKey="Garcia Espa A, E" uniqKey="Garcia Espa A E">E. García-España</name></author><author><name sortKey="Marti Bonmati, L" uniqKey="Marti Bonmati L">L. Martí-Bonmatí</name></author><author><name sortKey="Frias, J C" uniqKey="Frias J">J.C. Frias</name></author><author><name sortKey="Albelda, M T" uniqKey="Albelda M">M.T. Albelda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Busatto, S" uniqKey="Busatto S">S. Busatto</name></author><author><name sortKey="Pham, A" uniqKey="Pham A">A. Pham</name></author><author><name sortKey="Suh, A" uniqKey="Suh A">A. Suh</name></author><author><name sortKey="Shapiro, S" uniqKey="Shapiro S">S. Shapiro</name></author><author><name sortKey="Wolfram, J" uniqKey="Wolfram J">J. Wolfram</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author><author><name sortKey="Jiang, M" uniqKey="Jiang M">M. Jiang</name></author><author><name sortKey="Deng, S" uniqKey="Deng S">S. Deng</name></author><author><name sortKey="Lu, J" uniqKey="Lu J">J. Lu</name></author><author><name sortKey="Huang, H" uniqKey="Huang H">H. Huang</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Gong, P" uniqKey="Gong P">P. Gong</name></author><author><name sortKey="Shen, X" uniqKey="Shen X">X. Shen</name></author><author><name sortKey="Ruan, H" uniqKey="Ruan H">H. Ruan</name></author><author><name sortKey="Jin, M" uniqKey="Jin M">M. Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Luo, Q" uniqKey="Luo Q">Q. Luo</name></author><author><name sortKey="Guo, D" uniqKey="Guo D">D. Guo</name></author><author><name sortKey="Liu, G" uniqKey="Liu G">G. Liu</name></author><author><name sortKey="Chen, G" uniqKey="Chen G">G. Chen</name></author><author><name sortKey="Hang, M" uniqKey="Hang M">M. Hang</name></author><author><name sortKey="Jin, M" uniqKey="Jin M">M. Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pan, J" uniqKey="Pan J">J. Pan</name></author><author><name sortKey="Alimujiang, M" uniqKey="Alimujiang M">M. Alimujiang</name></author><author><name sortKey="Chen, Q" uniqKey="Chen Q">Q. Chen</name></author><author><name sortKey="Shi, H" uniqKey="Shi H">H. Shi</name></author><author><name sortKey="Luo, X" uniqKey="Luo X">X. Luo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Work, L M" uniqKey="Work L">L.M. Work</name></author><author><name sortKey="Nicol, C G" uniqKey="Nicol C">C.G. Nicol</name></author><author><name sortKey="Denby, L" uniqKey="Denby L">L. Denby</name></author><author><name sortKey="Baker, A H" uniqKey="Baker A">A.H. Baker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zahid, M" uniqKey="Zahid M">M. Zahid</name></author><author><name sortKey="Phillips, B E" uniqKey="Phillips B">B.E. Phillips</name></author><author><name sortKey="Albers, S M" uniqKey="Albers S">S.M. Albers</name></author><author><name sortKey="Giannoukakis, N" uniqKey="Giannoukakis N">N. Giannoukakis</name></author><author><name sortKey="Watkins, S C" uniqKey="Watkins S">S.C. Watkins</name></author><author><name sortKey="Robbins, P D" uniqKey="Robbins P">P.D. Robbins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanki, S" uniqKey="Kanki S">S. Kanki</name></author><author><name sortKey="Jaalouk, D E" uniqKey="Jaalouk D">D.E. Jaalouk</name></author><author><name sortKey="Lee, S" uniqKey="Lee S">S. Lee</name></author><author><name sortKey="Yu, A Y C" uniqKey="Yu A">A.Y.C. Yu</name></author><author><name sortKey="Gannon, J" uniqKey="Gannon J">J. Gannon</name></author><author><name sortKey="Lee, R T" uniqKey="Lee R">R.T. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, G" uniqKey="Sharma G">G. Sharma</name></author><author><name sortKey="Sharma, A R" uniqKey="Sharma A">A.R. Sharma</name></author><author><name sortKey="Lee, S S" uniqKey="Lee S">S.-S. Lee</name></author><author><name sortKey="Bhattacharya, M" uniqKey="Bhattacharya M">M. Bhattacharya</name></author><author><name sortKey="Nam, J S" uniqKey="Nam J">J.-S. Nam</name></author><author><name sortKey="Chakraborty, C" uniqKey="Chakraborty C">C. Chakraborty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, T" uniqKey="Yang T">T. Yang</name></author><author><name sortKey="Martin, P" uniqKey="Martin P">P. Martin</name></author><author><name sortKey="Fogarty, B" uniqKey="Fogarty B">B. Fogarty</name></author><author><name sortKey="Brown, A" uniqKey="Brown A">A. Brown</name></author><author><name sortKey="Schurman, K" uniqKey="Schurman K">K. Schurman</name></author><author><name sortKey="Phipps, R" uniqKey="Phipps R">R. Phipps</name></author><author><name sortKey="Yin, V P" uniqKey="Yin V">V.P. Yin</name></author><author><name sortKey="Lockman, P" uniqKey="Lockman P">P. Lockman</name></author><author><name sortKey="Bai, S" uniqKey="Bai S">S. Bai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xin, H" uniqKey="Xin H">H. Xin</name></author><author><name sortKey="Katakowski, M" uniqKey="Katakowski M">M. Katakowski</name></author><author><name sortKey="Wang, F" uniqKey="Wang F">F. Wang</name></author><author><name sortKey="Qian, J Y" uniqKey="Qian J">J.Y. Qian</name></author><author><name sortKey="Liu, X S" uniqKey="Liu X">X.S. Liu</name></author><author><name sortKey="Ali, M M" uniqKey="Ali M">M.M. Ali</name></author><author><name sortKey="Buller, B" uniqKey="Buller B">B. Buller</name></author><author><name sortKey="Zhang, Z G" uniqKey="Zhang Z">Z.G. Zhang</name></author><author><name sortKey="Chopp, M" uniqKey="Chopp M">M. Chopp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alvarez Erviti, L" uniqKey="Alvarez Erviti L">L. Alvarez-Erviti</name></author><author><name sortKey="Seow, Y" uniqKey="Seow Y">Y. Seow</name></author><author><name sortKey="Yin, H" uniqKey="Yin H">H. Yin</name></author><author><name sortKey="Betts, C" uniqKey="Betts C">C. Betts</name></author><author><name sortKey="Lakhal, S" uniqKey="Lakhal S">S. Lakhal</name></author><author><name sortKey="Wood, M J A" uniqKey="Wood M">M.J.A. Wood</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, B" uniqKey="Yang B">B. Yang</name></author><author><name sortKey="Chen, Y" uniqKey="Chen Y">Y. Chen</name></author><author><name sortKey="Shi, J" uniqKey="Shi J">J. Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="He, C" uniqKey="He C">C. He</name></author><author><name sortKey="Zheng, S" uniqKey="Zheng S">S. Zheng</name></author><author><name sortKey="Luo, Y" uniqKey="Luo Y">Y. Luo</name></author><author><name sortKey="Wang, B" uniqKey="Wang B">B. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, A" uniqKey="Tan A">A. Tan</name></author><author><name sortKey="Rajadas, J" uniqKey="Rajadas J">J. Rajadas</name></author><author><name sortKey="Seifalian, A M" uniqKey="Seifalian A">A.M. Seifalian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, J" uniqKey="Huang J">J. Huang</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Orza, A" uniqKey="Orza A">A. Orza</name></author><author><name sortKey="Lu, Q" uniqKey="Lu Q">Q. Lu</name></author><author><name sortKey="Guo, P" uniqKey="Guo P">P. Guo</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author><author><name sortKey="Mao, H" uniqKey="Mao H">H. Mao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, N" uniqKey="Zhao N">N. Zhao</name></author><author><name sortKey="Yan, L" uniqKey="Yan L">L. Yan</name></author><author><name sortKey="Zhao, X" uniqKey="Zhao X">X. Zhao</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Li, A" uniqKey="Li A">A. Li</name></author><author><name sortKey="Zheng, D" uniqKey="Zheng D">D. Zheng</name></author><author><name sortKey="Zhou, X" uniqKey="Zhou X">X. Zhou</name></author><author><name sortKey="Dai, X" uniqKey="Dai X">X. Dai</name></author><author><name sortKey="Xu, F J" uniqKey="Xu F">F.J. Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kelkar, S S" uniqKey="Kelkar S">S.S. Kelkar</name></author><author><name sortKey="Reineke, T M" uniqKey="Reineke T">T.M. Reineke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silva, A K A" uniqKey="Silva A">A.K.A. Silva</name></author><author><name sortKey="Luciani, N" uniqKey="Luciani N">N. Luciani</name></author><author><name sortKey="Gazeau, F" uniqKey="Gazeau F">F. Gazeau</name></author><author><name sortKey="Aubertin, K" uniqKey="Aubertin K">K. Aubertin</name></author><author><name sortKey="Bonneau, S" uniqKey="Bonneau S">S. Bonneau</name></author><author><name sortKey="Chauvierre, C" uniqKey="Chauvierre C">C. Chauvierre</name></author><author><name sortKey="Letourneur, D" uniqKey="Letourneur D">D. Letourneur</name></author><author><name sortKey="Wilhelm, C" uniqKey="Wilhelm C">C. Wilhelm</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Lu, Z" uniqKey="Lu Z">Z. Lu</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name></author><author><name sortKey="Li, Q" uniqKey="Li Q">Q. Li</name></author><author><name sortKey="Du, W" uniqKey="Du W">W. Du</name></author><author><name sortKey="Feng, X" uniqKey="Feng X">X. Feng</name></author><author><name sortKey="Jia, H" uniqKey="Jia H">H. Jia</name></author><author><name sortKey="Liu, B F" uniqKey="Liu B">B.F. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jia, G" uniqKey="Jia G">G. Jia</name></author><author><name sortKey="Han, Y" uniqKey="Han Y">Y. Han</name></author><author><name sortKey="An, Y" uniqKey="An Y">Y. An</name></author><author><name sortKey="Ding, Y" uniqKey="Ding Y">Y. Ding</name></author><author><name sortKey="He, C" uniqKey="He C">C. He</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X. Wang</name></author><author><name sortKey="Tang, Q" uniqKey="Tang Q">Q. Tang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, T Y" uniqKey="Tang T">T.Y. Tang</name></author><author><name sortKey="Howarth, S P S" uniqKey="Howarth S">S.P.S. Howarth</name></author><author><name sortKey="Miller, S R" uniqKey="Miller S">S.R. Miller</name></author><author><name sortKey="Graves, M J" uniqKey="Graves M">M.J. Graves</name></author><author><name sortKey="Patterson, A J" uniqKey="Patterson A">A.J. Patterson</name></author><author><name sortKey="U King Im, J M" uniqKey="U King Im J">J.-M. U-King-Im</name></author><author><name sortKey="Li, Z Y" uniqKey="Li Z">Z.Y. Li</name></author><author><name sortKey="Walsh, S R" uniqKey="Walsh S">S.R. Walsh</name></author><author><name sortKey="Brown, A P" uniqKey="Brown A">A.P. Brown</name></author><author><name sortKey="Kirkpatrick, P J" uniqKey="Kirkpatrick P">P.J. Kirkpatrick</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, J W" uniqKey="Wang J">J.W. Wang</name></author><author><name sortKey="Gijsberts, C M" uniqKey="Gijsberts C">C.M. Gijsberts</name></author><author><name sortKey="Seneviratna, A" uniqKey="Seneviratna A">A. Seneviratna</name></author><author><name sortKey="De Hoog, V C" uniqKey="De Hoog V">V.C. De Hoog</name></author><author><name sortKey="Vrijenhoek, J E P" uniqKey="Vrijenhoek J">J.E.P. Vrijenhoek</name></author><author><name sortKey="Schoneveld, A H" uniqKey="Schoneveld A">A.H. Schoneveld</name></author><author><name sortKey="Chan, M Y" uniqKey="Chan M">M.Y. Chan</name></author><author><name sortKey="Lam, C S P" uniqKey="Lam C">C.S.P. Lam</name></author><author><name sortKey="Richards, A M" uniqKey="Richards A">A.M. Richards</name></author><author><name sortKey="Lee, C N" uniqKey="Lee C">C.N. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amosse, J" uniqKey="Amosse J">J. Amosse</name></author><author><name sortKey="Carmen Martinez, M" uniqKey="Carmen Martinez M">M. Carmen Martinez</name></author><author><name sortKey="Le Lay, S" uniqKey="Le Lay S">S. Le Lay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jang, S C" uniqKey="Jang S">S.C. Jang</name></author><author><name sortKey="Kim, O Y" uniqKey="Kim O">O.Y. Kim</name></author><author><name sortKey="Yoon, C M" uniqKey="Yoon C">C.M. Yoon</name></author><author><name sortKey="Choi, D S" uniqKey="Choi D">D.S. Choi</name></author><author><name sortKey="Roh, T Y" uniqKey="Roh T">T.Y. Roh</name></author><author><name sortKey="Park, J" uniqKey="Park J">J. Park</name></author><author><name sortKey="Nilsson, J" uniqKey="Nilsson J">J. Nilsson</name></author><author><name sortKey="Lotvall, J" uniqKey="Lotvall J">J. Lötvall</name></author><author><name sortKey="Kim, Y K" uniqKey="Kim Y">Y.K. Kim</name></author><author><name sortKey="Gho, Y S" uniqKey="Gho Y">Y.S. Gho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, T" uniqKey="Wu T">T. Wu</name></author><author><name sortKey="Zhang, D" uniqKey="Zhang D">D. Zhang</name></author><author><name sortKey="Qiao, Q" uniqKey="Qiao Q">Q. Qiao</name></author><author><name sortKey="Qin, X" uniqKey="Qin X">X. Qin</name></author><author><name sortKey="Yang, C" uniqKey="Yang C">C. Yang</name></author><author><name sortKey="Kong, M" uniqKey="Kong M">M. Kong</name></author><author><name sortKey="Deng, H" uniqKey="Deng H">H. Deng</name></author><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goh, W J" uniqKey="Goh W">W.J. Goh</name></author><author><name sortKey="Zou, S" uniqKey="Zou S">S. Zou</name></author><author><name sortKey="Ong, W Y" uniqKey="Ong W">W.Y. Ong</name></author><author><name sortKey="Torta, F" uniqKey="Torta F">F. Torta</name></author><author><name sortKey="Alexandra, A F" uniqKey="Alexandra A">A.F. Alexandra</name></author><author><name sortKey="Schiffelers, R M" uniqKey="Schiffelers R">R.M. Schiffelers</name></author><author><name sortKey="Storm, G" uniqKey="Storm G">G. Storm</name></author><author><name sortKey="Wang, J W" uniqKey="Wang J">J.W. Wang</name></author><author><name sortKey="Czarny, B" uniqKey="Czarny B">B. Czarny</name></author><author><name sortKey="Pastorin, G" uniqKey="Pastorin G">G. Pastorin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, H Y" uniqKey="Kim H">H.Y. Kim</name></author><author><name sortKey="Kumar, H" uniqKey="Kumar H">H. Kumar</name></author><author><name sortKey="Jo, M J" uniqKey="Jo M">M.J. Jo</name></author><author><name sortKey="Kim, J" uniqKey="Kim J">J. Kim</name></author><author><name sortKey="Yoon, J K" uniqKey="Yoon J">J.K. Yoon</name></author><author><name sortKey="Lee, J R" uniqKey="Lee J">J.R. Lee</name></author><author><name sortKey="Kang, M" uniqKey="Kang M">M. Kang</name></author><author><name sortKey="Choo, Y W" uniqKey="Choo Y">Y.W. Choo</name></author><author><name sortKey="Song, S Y" uniqKey="Song S">S.Y. Song</name></author><author><name sortKey="Kwon, S P" uniqKey="Kwon S">S.P. Kwon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goh, W J" uniqKey="Goh W">W.J. Goh</name></author><author><name sortKey="Lee, C K" uniqKey="Lee C">C.K. Lee</name></author><author><name sortKey="Zou, S" uniqKey="Zou S">S. Zou</name></author><author><name sortKey="Woon, E C Y" uniqKey="Woon E">E.C.Y. Woon</name></author><author><name sortKey="Czarny, B" uniqKey="Czarny B">B. Czarny</name></author><author><name sortKey="Pastorin, G" uniqKey="Pastorin G">G. Pastorin</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Mol Sci</journal-id><journal-id journal-id-type="iso-abbrev">Int J Mol Sci</journal-id><journal-id journal-id-type="publisher-id">ijms</journal-id><journal-title-group><journal-title>International Journal of Molecular Sciences</journal-title></journal-title-group><issn pub-type="epub">1422-0067</issn><publisher><publisher-name>MDPI</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31277271</article-id><article-id pub-id-type="pmc">6650854</article-id><article-id pub-id-type="doi">10.3390/ijms20133272</article-id><article-id pub-id-type="publisher-id">ijms-20-03272</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Extracellular Vesicles in Cardiovascular Diseases: Alternative Biomarker Sources, Therapeutic Agents, and Drug Delivery Carriers</article-title></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="true">https://orcid.org/0000-0002-3627-4025</contrib-id><name><surname>Chong</surname><given-names>Suet Yen</given-names></name><xref ref-type="aff" rid="af1-ijms-20-03272">1</xref><xref ref-type="aff" rid="af2-ijms-20-03272">2</xref><xref ref-type="author-notes" rid="fn1-ijms-20-03272">†</xref></contrib><contrib contrib-type="author"><name><surname>Lee</surname><given-names>Choon Keong</given-names></name><xref ref-type="aff" rid="af3-ijms-20-03272">3</xref><xref ref-type="author-notes" rid="fn1-ijms-20-03272">†</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Chenyuan</given-names></name><xref ref-type="aff" rid="af1-ijms-20-03272">1</xref><xref ref-type="aff" rid="af2-ijms-20-03272">2</xref></contrib><contrib contrib-type="author"><name><surname>Ou</surname><given-names>Yi Hsuan</given-names></name><xref ref-type="aff" rid="af3-ijms-20-03272">3</xref></contrib><contrib contrib-type="author"><name><surname>Charles</surname><given-names>Christopher J.</given-names></name><xref ref-type="aff" rid="af1-ijms-20-03272">1</xref><xref ref-type="aff" rid="af2-ijms-20-03272">2</xref></contrib><contrib contrib-type="author"><name><surname>Richards</surname><given-names>Arthur Mark</given-names></name><xref ref-type="aff" rid="af2-ijms-20-03272">2</xref><xref ref-type="aff" rid="af4-ijms-20-03272">4</xref></contrib><contrib contrib-type="author"><name><surname>Neupane</surname><given-names>Yub Raj</given-names></name><xref ref-type="aff" rid="af3-ijms-20-03272">3</xref></contrib><contrib contrib-type="author"><name><surname>Pavon</surname><given-names>Maria Vazquez</given-names></name><xref ref-type="aff" rid="af3-ijms-20-03272">3</xref></contrib><contrib contrib-type="author"><name><surname>Zharkova</surname><given-names>Olga</given-names></name><xref ref-type="aff" rid="af1-ijms-20-03272">1</xref><xref ref-type="aff" rid="af2-ijms-20-03272">2</xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="true">https://orcid.org/0000-0002-2568-0626</contrib-id><name><surname>Pastorin</surname><given-names>Giorgia</given-names></name><xref ref-type="aff" rid="af3-ijms-20-03272">3</xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="true">https://orcid.org/0000-0001-7986-6082</contrib-id><name><surname>Wang</surname><given-names>Jiong-Wei</given-names></name><xref ref-type="aff" rid="af1-ijms-20-03272">1</xref><xref ref-type="aff" rid="af2-ijms-20-03272">2</xref><xref ref-type="aff" rid="af5-ijms-20-03272">5</xref><xref rid="c1-ijms-20-03272" ref-type="corresp">*</xref></contrib></contrib-group><aff id="af1-ijms-20-03272"><label>1</label>Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore</aff><aff id="af2-ijms-20-03272"><label>2</label>Cardiovascular Research Institute (CVRI), National University Heart Centre Singapore (NUHCS), Singapore 117599, Singapore</aff><aff id="af3-ijms-20-03272"><label>3</label>Department of Pharmacy, National University of Singapore, Singapore 117543, Singapore</aff><aff id="af4-ijms-20-03272"><label>4</label>Department of Medicine, National University Hospital, Singapore 119228, Singapore</aff><aff id="af5-ijms-20-03272"><label>5</label>Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117593, Singapore</aff><author-notes><corresp id="c1-ijms-20-03272"><label>*</label>Correspondence: <email>surwang@nus.edu.sg</email>; Tel.: +65-66011387</corresp><fn id="fn1-ijms-20-03272"><label>†</label><p>These authors contributed equally to this work.</p></fn></author-notes><pub-date pub-type="epub"><day>03</day><month>7</month><year>2019</year></pub-date><pub-date pub-type="collection"><month>7</month><year>2019</year></pub-date><volume>20</volume><issue>13</issue><elocation-id>3272</elocation-id><history><date date-type="received"><day>04</day><month>6</month><year>2019</year></date><date date-type="accepted"><day>01</day><month>7</month><year>2019</year></date></history><permissions><copyright-statement>© 2019 by the authors.</copyright-statement><copyright-year>2019</copyright-year><license license-type="open-access"><license-p>Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>).</license-p></license></permissions><abstract><p>Cardiovascular diseases (CVD) represent the leading cause of morbidity and mortality globally. The emerging role of extracellular vesicles (EVs) in intercellular communication has stimulated renewed interest in exploring the potential application of EVs as tools for diagnosis, prognosis, and therapy in CVD. The ubiquitous nature of EVs in biological fluids presents a technological advantage compared to current diagnostic tools by virtue of their notable stability. EV contents, such as proteins and microRNAs, represent specific signatures of cellular activation or injury. This feature positions EVs as an alternative source of biomarkers. Furthermore, their intrinsic activity and immunomodulatory properties offer EVs unique opportunities to act as therapeutic agents per se or to serve as drug delivery carriers by acting as miniaturized vehicles incorporating bioactive molecules. In this article, we aim to review the recent advances and applications of EV-based biomarkers and therapeutics. In addition, the potential of EVs as a drug delivery and theranostic platform for CVD will also be discussed.</p></abstract><kwd-group><kwd>extracellular vesicles</kwd><kwd>cardiovascular disease</kwd><kwd>biomarker</kwd><kwd>therapeutic</kwd><kwd>drug delivery</kwd><kwd>theranostics</kwd></kwd-group></article-meta></front><floats-group><fig id="ijms-20-03272-f001" orientation="portrait" position="float"><label>Figure 1</label><caption><p>Schematic diagram illustrating EVs as an alternative source of biomarkers in cardiovascular disease (CVD). Extracellular vesicle (EV) proteins, such as CD14, cystatin C and coagulation-related proteins including Serpin G1 and Serpin F2, have been proposed as novel biomarkers for diagnosis and prognosis of heart failure, vascular disease, and stroke. Conventional CVD risk factors, such as obesity and smoking, have been associated with EV protein contents, including CD14, cystatin C, and procoagulant proteins. Certain EV miRNAs have also been identified as novel diagnostic and prognostic biomarkers for stroke and heart failure. Five EV miRNAs are listed as representatives. EV lipids, however, remain largely unexplored in the diagnosis or prognosis of CVD. CVD, cardiovascular diseases; CS, complement system; C5a, complement factor 5a; pIgR, polygenic immunoglobulin receptor; PS, phosphatidylserine; PE, phosphatidylethanolamine.</p></caption><graphic xlink:href="ijms-20-03272-g001"></graphic></fig><fig id="ijms-20-03272-f002" orientation="portrait" position="float"><label>Figure 2</label><caption><p>Potential applications of EVs in diagnostic, therapeutic, and drug delivery in CVD. Increasing novel biomarkers identified in EVs have made them as attractive alternative sources of biomarkers for a variety of CVD. On the other hand, EVs also bear intrinsic therapeutic activities and great potential to deliver drugs or therapeutic compounds and therefore, may offer synergistic treatment effects. Endogenous EV biomarkers and/or loaded diagnostic agents may be housed together with therapeutic compounds to create theranostic EVs for CVD treatment. STEMI, ST-elevation myocardial infarction.</p></caption><graphic xlink:href="ijms-20-03272-g002"></graphic></fig><table-wrap id="ijms-20-03272-t001" orientation="portrait" position="float"><object-id pub-id-type="pii">ijms-20-03272-t001_Table 1</object-id><label>Table 1</label><caption><p>Summary of extracellular vesicle contents as diagnostic or prognostic biomarkers in CVD.</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Disease </th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Sample Size</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Source</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Methods of Isolation</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">EVs Characterized</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Screening Method</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Quantification Method</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Analytes Measured</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Significant Candidates </th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Potential Application</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Ref.</th></tr></thead><tbody><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Acute Ischemic Stroke</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">50</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Serum</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Based on previous reports</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">RT-qPCR<break></break></td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-134</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-134</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis and prognosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B59-ijms-20-03272" ref-type="bibr">59</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Acute Ischemic Stroke</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">50</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Serum</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Based on previous reports</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">RT-qPCR</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-223</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-223</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis and prognosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B60-ijms-20-03272" ref-type="bibr">60</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Heart Failure</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">31</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Not available</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Based on previous reports</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">RT-qPCR</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-221, miR-15a, miR-122, miR-21, miR-29, miR-30d, miR-133a, miR-425, miR-744</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-21, miR-425, miR-744</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis, prognosis<break></break><break></break>and therapeutic candidates</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B62-ijms-20-03272" ref-type="bibr">62</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Acute Heart Failure</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">28</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Serum</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; Western blot; DLS</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Based on previous reports</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">RT-qPCR</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-92b-5p, <break></break>miR-192-5p,<break></break>miR-320a</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-92b-5p</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B63-ijms-20-03272" ref-type="bibr">63</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Acute Myocardial Infarction</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">21</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Serum</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miRNA profiling through TaqMan Human MicroRNA Array</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">RT-qPCR; </td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">377 miRNAs</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-192, miR-194, miR-34a</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Prognosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B64-ijms-20-03272" ref-type="bibr">64</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Atrial fibrillation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">40</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Serum</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; NTA; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miRNA microarray</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">RT-qPCR</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-107, miR-320d, miR-103a, miR-486, miR-let-7b</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-107, miR-320d, miR-103a, miR-486, miR-let-7b</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis, prognosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B57-ijms-20-03272" ref-type="bibr">57</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Hyper-tension</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">22</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Serum </td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Ultra-centrifugation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; Immune-gold labelling</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Nanostring nCounter<sup>®</sup> platform</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Nanostring nCounter<sup>®</sup> platform</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">800 miRNAs</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-199a/b, miR-223–3p</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Early diagnosis </td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B67-ijms-20-03272" ref-type="bibr">67</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Obesity</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">883</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Ultra-centrifugation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; FACS; NTA</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miRNA screening through QuantStudio™12 K FlexOpenArray<sup>®</sup> Platform</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miRNA screening through QuantStudio™12 K FlexOpenArray<sup>®</sup> Platform</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">754 miRNAs</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-let-7c-5p, <break></break>miR-106a-5p,<break></break>miR-143-3p; miR-185-5p, miR-218-5p; miR-331-3p, miR-642-5p, miR-652-3p, miR-99b-5p</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Early diagnosis </td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B68-ijms-20-03272" ref-type="bibr">68</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Coronary Artery Disease</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">21</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Column-based system (Exo-spin Mini Columns)</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">NTA; TEM; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Based on previous reports</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">RT-qPCR</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">14 miRNAs</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">miR-1, miR-24, miR-133a, miR-133b, miR-210</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B73-ijms-20-03272" ref-type="bibr">73</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Acute Coronary Syndrome</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">475</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Serum</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; FACS; NTA; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Differential quantitative proteomics and ingenuity pathway analysis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Multiplex immunoassay</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">polygenic immunoglobulin receptor (pIgR), cystatin C, and complement factor C5a</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">pIgR, cystatin C</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B40-ijms-20-03272" ref-type="bibr">40</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Acute Myocardial Infarction</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">25</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Ultra-centrifugation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">FACS; TEM; DLS</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">2D-DIGE; LC-MS/MS; MALDI-TOF coupled with ingenuity pathway analysis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">2D-DIGE; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">25 ORFs derived from 102 differentially regulated proteins spot identified through 2D-DIGE</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">A2-macroglobulin isoforms, Fibrinogen, Viperin</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Diagnosis and therapeutic targets</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B80-ijms-20-03272" ref-type="bibr">80</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Vascular Disease</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">1060</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; FACS; NTA; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Differential quantitative proteomics and ingenuity pathway analysis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Multiplex immunoassay</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Cystatin C, Serpin G1, Serpin F2, and CD14</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Cystatin C, Serpin F2, and CD14</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Prognosis </td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B41-ijms-20-03272" ref-type="bibr">41</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Dyspnea and Heart Failure</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">404</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Sequential density precipitation </td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Based on previous study</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Multiplex immunoassay</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Cystatin C, Serpin G1, Serpin F2, and CD14</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">CD14, SerpinG1, and SerpinF2</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Prognosis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B42-ijms-20-03272" ref-type="bibr">42</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Vascular Disease and Obesity</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">1060</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Precipitation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; FACS; NTA; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Differential quantitative proteomics and ingenuity pathway analysis</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Multiplex immunoassay</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Cystatin C, Serpin G1, Serpin F2, and CD14</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Cystatin C, CD14</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Prognosis and therapeutic target</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B81-ijms-20-03272" ref-type="bibr">81</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Obesity</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">22</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Plasma</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Ultra-centrifugation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">TEM; FACS; NTA; Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">2D-DIGE-based proteomic approach</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">2D-Western blot</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Entire Proteome</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">C3, C4, Fibrinogen, Adiponectin</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Early diagnosis </td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B82-ijms-20-03272" ref-type="bibr">82</xref>]</td></tr></tbody></table></table-wrap><table-wrap id="ijms-20-03272-t002" orientation="portrait" position="float"><object-id pub-id-type="pii">ijms-20-03272-t002_Table 2</object-id><label>Table 2</label><caption><p>Selected examples of liposomal formulation used in the in vivo model for treatment of CVD.</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Therapeutics Encapsulated</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">In vivo Model</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Outcome</th><th align="center" valign="middle" style="border-top:solid thin;border-bottom:solid thin" rowspan="1" colspan="1">Ref.</th></tr></thead><tbody><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Simvastatin/Alendronate</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Carotid-injured rat model</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Suppressed neointimal formation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B171-ijms-20-03272" ref-type="bibr">171</xref>,<xref rid="B172-ijms-20-03272" ref-type="bibr">172</xref>] </td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Nitric oxide</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Carotid-injured rabbit model</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Suppressed neointimal formation</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B173-ijms-20-03272" ref-type="bibr">173</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Berberine</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Myocardial infarction murine model</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Improvement of cardiac function</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B152-ijms-20-03272" ref-type="bibr">152</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">VEGF</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Myocardial infarction rat model</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Improved cardiac functions</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B174-ijms-20-03272" ref-type="bibr">174</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Cyclopentenone prostaglandin</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Hyperlipemic diet atherosclerotic murine model</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Vascular injuries recovery</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B175-ijms-20-03272" ref-type="bibr">175</xref>]</td></tr><tr><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Fumagillin</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Hyperlipemic diet atherosclerotic murine model</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">Reduced atherosclerotic lesions</td><td align="center" valign="middle" style="border-bottom:solid thin" rowspan="1" colspan="1">[<xref rid="B176-ijms-20-03272" ref-type="bibr">176</xref>]</td></tr></tbody></table></table-wrap></floats-group></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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