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Qualitative and Quantitative Microbiological Studies of Paediatric Artemether-Lumefantrine Dry Powders and Paracetamol Syrups Obtained from Selected Drug Stores in Accra, Ghana

Identifieur interne : 000684 ( Pmc/Curation ); précédent : 000683; suivant : 000685

Qualitative and Quantitative Microbiological Studies of Paediatric Artemether-Lumefantrine Dry Powders and Paracetamol Syrups Obtained from Selected Drug Stores in Accra, Ghana

Auteurs : Solomon Opoku [Ghana] ; Isaac Nyanor [Ghana]

Source :

RBID : PMC:6662472

Abstract

Infants and children under five years generally have high susceptibility to pathogenic and opportunistic infections due to immaturity and inexperience of their immune responses. The lives of these young children are threatened when they consume pharmaceutical preparations of poor microbiological quality. Considering the widespread use of artemether-lumefantrine dry powder and paracetamol syrup among the general population in Ghana, there is a need to investigate the microbiological quality and safety of these paediatric pharmaceutical preparations. The study investigated the microbiological quality of 180 samples comprising 90 artemether-lumefantrine dry powders and 90 paracetamol syrups. The samples were tested for presence of specified indicator pathogens, Total Aerobic Microbial Count (TAMC), and Total Yeasts and Moulds Count (TYMC) using compendial procedures. Results from the study indicated that 16 (17.78%) of the paracetamol syrup samples showed bioburden levels above United States Pharmacopeia (USP) maximum acceptable limit, but none of the artemether-lumefantrine dry powder samples recorded microbial load above the limit of USP. Four samples of paracetamol syrup and 4 samples of artemether-lumefantrine dry powder showed presence of P. aeruginosa, whereas 5 samples of paracetamol syrup were found to be contaminated with Salmonella spp. Overall, 4.44% of the artemether-lumefantrine dry powders and 25.56% of the paracetamol syrups were found to be noncompliant with USP specifications for nonsterile pharmaceutical preparations for oral use. This study has revealed the existence of substandard paediatric pharmaceutical products in the Ghanaian market, hence the need for regulatory bodies to intensify monitoring and postmarketing surveillance programmes to help get rid of these products from the market.


Url:
DOI: 10.1155/2019/7062016
PubMed: 31379951
PubMed Central: 6662472

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PMC:6662472

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</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">31379951</article-id>
<article-id pub-id-type="pmc">6662472</article-id>
<article-id pub-id-type="doi">10.1155/2019/7062016</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Qualitative and Quantitative Microbiological Studies of Paediatric Artemether-Lumefantrine Dry Powders and Paracetamol Syrups Obtained from Selected Drug Stores in Accra, Ghana</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<contrib-id contrib-id-type="orcid" authenticated="false">https://orcid.org/0000-0002-2541-466X</contrib-id>
<name>
<surname>Opoku</surname>
<given-names>Solomon</given-names>
</name>
<email>slmnopoku@gmail.com</email>
<xref ref-type="aff" rid="I1">
<sup>1</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Nyanor</surname>
<given-names>Isaac</given-names>
</name>
<xref ref-type="aff" rid="I2">
<sup>2</sup>
</xref>
</contrib>
</contrib-group>
<aff id="I1">
<sup>1</sup>
Quality Control Department, Entrance Pharmaceuticals and Research Centre, No. 16 Okpoi Gonno, Spintex Road, Post Office Box CT 10805, Accra, Ghana</aff>
<aff id="I2">
<sup>2</sup>
Sickle Pan Africa Research Consortium, Kumasi Centre for Sickle Cell Disease, Komfo Anokye Teaching Hospital, Kumasi, Ghana</aff>
<author-notes>
<fn fn-type="other">
<p>Academic Editor: Aditya Prasad Dash</p>
</fn>
</author-notes>
<pub-date pub-type="collection">
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>14</day>
<month>7</month>
<year>2019</year>
</pub-date>
<volume>2019</volume>
<elocation-id>7062016</elocation-id>
<history>
<date date-type="received">
<day>11</day>
<month>3</month>
<year>2019</year>
</date>
<date date-type="accepted">
<day>7</day>
<month>7</month>
<year>2019</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright © 2019 Solomon Opoku and Isaac Nyanor.</copyright-statement>
<copyright-year>2019</copyright-year>
<license xlink:href="https://creativecommons.org/licenses/by/4.0/">
<license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract>
<p>Infants and children under five years generally have high susceptibility to pathogenic and opportunistic infections due to immaturity and inexperience of their immune responses. The lives of these young children are threatened when they consume pharmaceutical preparations of poor microbiological quality. Considering the widespread use of artemether-lumefantrine dry powder and paracetamol syrup among the general population in Ghana, there is a need to investigate the microbiological quality and safety of these paediatric pharmaceutical preparations. The study investigated the microbiological quality of 180 samples comprising 90 artemether-lumefantrine dry powders and 90 paracetamol syrups. The samples were tested for presence of specified indicator pathogens, Total Aerobic Microbial Count (TAMC), and Total Yeasts and Moulds Count (TYMC) using compendial procedures. Results from the study indicated that 16 (17.78%) of the paracetamol syrup samples showed bioburden levels above United States Pharmacopeia (USP) maximum acceptable limit, but none of the artemether-lumefantrine dry powder samples recorded microbial load above the limit of USP. Four samples of paracetamol syrup and 4 samples of artemether-lumefantrine dry powder showed presence of
<italic> P</italic>
.
<italic> aeruginosa</italic>
, whereas 5 samples of paracetamol syrup were found to be contaminated with
<italic> Salmonella</italic>
spp. Overall, 4.44% of the artemether-lumefantrine dry powders and 25.56% of the paracetamol syrups were found to be noncompliant with USP specifications for nonsterile pharmaceutical preparations for oral use. This study has revealed the existence of substandard paediatric pharmaceutical products in the Ghanaian market, hence the need for regulatory bodies to intensify monitoring and postmarketing surveillance programmes to help get rid of these products from the market.</p>
</abstract>
</article-meta>
</front>
<floats-group>
<table-wrap id="tab1" orientation="portrait" position="float">
<label>Table 1</label>
<caption>
<p>Proportion of products stratified by dosage forms, packaging materials, sources, and pathogens.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th rowspan="2" align="left" colspan="1">Variable</th>
<th colspan="2" align="center" rowspan="1">Product Type</th>
</tr>
<tr>
<th align="center" rowspan="1" colspan="1">Artemether-lumefantrine dry powder, N=90</th>
<th align="center" rowspan="1" colspan="1">Paracetamol syrup, N=90</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" rowspan="1" colspan="1">Dosage form</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Dry Powder for Oral Suspension</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">0</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Syrup</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">90</td>
</tr>
<tr>
<td colspan="3" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Primary packaging material</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Amber Glass Bottle</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">90</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">PET Bottle</td>
<td align="center" rowspan="1" colspan="1">79</td>
<td align="center" rowspan="1" colspan="1">0</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Sachet</td>
<td align="center" rowspan="1" colspan="1">11</td>
<td align="center" rowspan="1" colspan="1">0</td>
</tr>
<tr>
<td colspan="3" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Source of product</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">OTCMO</td>
<td align="center" rowspan="1" colspan="1">33</td>
<td align="center" rowspan="1" colspan="1">33</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Pharmacy Shop</td>
<td align="center" rowspan="1" colspan="1">57</td>
<td align="center" rowspan="1" colspan="1">57</td>
</tr>
<tr>
<td colspan="3" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Indicator Pathogens</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>E. coli</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">0</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>Salmonella spp.</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">5</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">85</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>P. aeruginosa </italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">4</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">86</td>
<td align="center" rowspan="1" colspan="1">86</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>S. aureus</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">0</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
</tr>
</tbody>
</table>
</table-wrap>
<table-wrap id="tab2" content-type="sidewaystable" orientation="portrait" position="float">
<label>Table 2</label>
<caption>
<p>Results of the microbiological analyses of artemether-lumefantrine dry powder and paracetamol syrup.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th rowspan="4" align="left" colspan="1">Brand</th>
<th rowspan="4" align="center" colspan="1">Sample No.</th>
<th colspan="6" align="center" rowspan="1">Artemether-lumefantrine Dry Powder</th>
<th colspan="6" align="center" rowspan="1">Paracetamol Syrup</th>
</tr>
<tr>
<th colspan="2" align="center" rowspan="1">Microbial Count</th>
<th colspan="4" align="center" rowspan="1">Pathogens</th>
<th colspan="2" align="center" rowspan="1">Microbial Count</th>
<th colspan="4" align="center" rowspan="1">Pathogens</th>
</tr>
<tr>
<th align="center" rowspan="1" colspan="1">TAMC</th>
<th align="center" rowspan="1" colspan="1">TYMC</th>
<th rowspan="2" align="center" colspan="1">
<italic>E</italic>
.
<italic>coli</italic>
</th>
<th rowspan="2" align="center" colspan="1">
<italic>Salmonella</italic>
spp.</th>
<th rowspan="2" align="center" colspan="1">
<italic>P</italic>
.
<italic>aeruginosa</italic>
</th>
<th rowspan="2" align="center" colspan="1">
<italic>S</italic>
.
<italic>aureus</italic>
</th>
<th align="center" rowspan="1" colspan="1">TAMC</th>
<th align="center" rowspan="1" colspan="1">TYMC</th>
<th rowspan="2" align="center" colspan="1">
<italic>E</italic>
.
<italic>coli</italic>
</th>
<th rowspan="2" align="center" colspan="1">
<italic>Salmonella</italic>
spp.</th>
<th rowspan="2" align="center" colspan="1">
<italic>P</italic>
.
<italic>aeruginosa</italic>
</th>
<th rowspan="2" align="center" colspan="1">
<italic>S</italic>
.
<italic>aureus</italic>
</th>
</tr>
<tr>
<th align="center" rowspan="1" colspan="1">(cfu/g)</th>
<th align="center" rowspan="1" colspan="1">(cfu/g)</th>
<th align="center" rowspan="1" colspan="1">(cfu/mL)</th>
<th align="center" rowspan="1" colspan="1">(cfu/mL)</th>
</tr>
</thead>
<tbody>
<tr>
<td rowspan="10" align="left" colspan="1">A</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">B</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">7.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">4.3 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.25 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">4.15 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">9.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.7 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.15 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">4.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">5.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.85 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">8.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">6.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">5.05 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">8.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">8.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">4.36 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">8.85 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">6.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">3.85 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">7.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">5.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">7.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">C</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.9 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.1 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">D</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.4 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.25 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">4.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.7 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">E</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">5.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">9.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">4.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">4.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">9.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">5.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">9.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">F</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.65 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">9.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">5.15 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.85 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">G</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.75 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.10 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.65 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">4.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">H</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">4.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">9.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.60 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.05 x 10
<sup>2</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td colspan="14" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td rowspan="10" align="left" colspan="1">I</td>
<td align="center" rowspan="1" colspan="1">1</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">2</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">3</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">2.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">2.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">6</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">3.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">7</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">3.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">9</td>
<td align="center" rowspan="1" colspan="1">5.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">Present</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
<tr>
<td align="center" rowspan="1" colspan="1">10</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">1.5 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">1.0 x 10
<sup>1</sup>
</td>
<td align="center" rowspan="1" colspan="1">< 10</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
<td align="center" rowspan="1" colspan="1">ND</td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn>
<p>TAMC: Total Aerobic Microbial Count, TYMC: Total Yeasts and Moulds Count, cfu: colony-forming units, ND: not detected.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="tab3" orientation="portrait" position="float">
<label>Table 3</label>
<caption>
<p>Associations between product type and presence of pathogens.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th rowspan="2" align="left" colspan="1">Pathogen</th>
<th colspan="2" align="center" rowspan="1">Product Type</th>
<th rowspan="2" align="center" colspan="1">Total</th>
<th rowspan="2" align="center" colspan="1">p-value</th>
</tr>
<tr>
<th align="center" rowspan="1" colspan="1">Artemether-lumefantrine Dry Powder</th>
<th align="center" rowspan="1" colspan="1">Paracetamol Syrup</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>Salmonella</italic>
spp.</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">85</td>
<td align="center" rowspan="1" colspan="1">175</td>
<td align="center" rowspan="1" colspan="1">
<italic>0.03∗</italic>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1">5</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Total</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">180</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td colspan="5" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>P. aeruginosa</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">86</td>
<td align="center" rowspan="1" colspan="1">86</td>
<td align="center" rowspan="1" colspan="1">172</td>
<td align="center" rowspan="1" colspan="1">0.64</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">8</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Total</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">180</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td colspan="5" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>S. aureus</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">180</td>
<td align="center" rowspan="1" colspan="1">-</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Total</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">180</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td colspan="5" rowspan="1">
<hr></hr>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>E. coli</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">180</td>
<td align="center" rowspan="1" colspan="1">-</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1">0</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Total</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">180</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn>
<p>
<bold></bold>
<italic>Fisher's test.</italic>
P< 0.05 means significant; P> 0.05 means not significant.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<table-wrap id="tab4" orientation="portrait" position="float">
<label>Table 4</label>
<caption>
<p>Relationship between the levels of contamination (TAMC) and presence of
<italic>P</italic>
.
<italic>aeruginosa</italic>
in the products packaged in amber glass bottles and PET bottles.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" rowspan="1" colspan="1">TAMC/Material Type/Disease-causing organisms </th>
<th align="center" rowspan="1" colspan="1">Observation</th>
<th align="center" rowspan="1" colspan="1">Wilcoxon Rank sum test</th>
<th align="center" rowspan="1" colspan="1">Expected frequency</th>
<th align="center" rowspan="1" colspan="1">p value</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" rowspan="1" colspan="1">Material Type (Amber Glass Bottle)</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>P</italic>
.
<italic>aeruginosa</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">86</td>
<td align="center" rowspan="1" colspan="1">3949.5</td>
<td align="center" rowspan="1" colspan="1">3913</td>
<td align="center" rowspan="1" colspan="1">0.4597</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">145.5</td>
<td align="center" rowspan="1" colspan="1">182</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Combined</td>
<td align="center" rowspan="1" colspan="1">90</td>
<td align="center" rowspan="1" colspan="1">4095</td>
<td align="center" rowspan="1" colspan="1">4095</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Material Type (PET Bottle)</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">
<italic>P</italic>
.
<italic>aeruginosa</italic>
</td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Absent</td>
<td align="center" rowspan="1" colspan="1">75</td>
<td align="center" rowspan="1" colspan="1">2879</td>
<td align="center" rowspan="1" colspan="1">3000</td>
<td align="center" rowspan="1" colspan="1">
<italic>0.0062</italic>
</td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Detected</td>
<td align="center" rowspan="1" colspan="1">4</td>
<td align="center" rowspan="1" colspan="1">281</td>
<td align="center" rowspan="1" colspan="1">160</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
<tr>
<td align="left" rowspan="1" colspan="1">Combined</td>
<td align="center" rowspan="1" colspan="1">79</td>
<td align="center" rowspan="1" colspan="1">3160</td>
<td align="center" rowspan="1" colspan="1">3160</td>
<td align="center" rowspan="1" colspan="1"></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn>
<p>P< 0.05 means significant; P> 0.05 means not significant.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</floats-group>
</pmc>
</record>

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