Degos-Like Lesions In Association With Connective Tissue Diseases: A Report Of Three Cases And Literature Review
Identifieur interne : 000285 ( Pmc/Curation ); précédent : 000284; suivant : 000286Degos-Like Lesions In Association With Connective Tissue Diseases: A Report Of Three Cases And Literature Review
Auteurs : Taptim Stavorn [Thaïlande] ; Kumutnart Chanprapaph [Thaïlande]Source :
- Clinical, Cosmetic and Investigational Dermatology [ 1178-7015 ] ; 2019.
Abstract
Degos disease is characterized by atrophic porcelain-white papules with peripheral erythema. Degos-like lesions have been reported in association with several connective tissue diseases (CTDs), mostly systemic lupus erythematosus (SLE), and rarely in dermatomyositis and systemic sclerosis. Herein, we report three cases of Degos-like lesions in CTDs. Two cases had Degos-like lesions linked to dermatomyositis. Both cases presented with severe inflammatory myopathy without pathognomonic cutaneous signs for dermatomyositis and lacked myositis-specific autoantibodies. Our third case, to our knowledge, is the first case of Degos-like lesions in association with overlapping systemic sclerosis and SLE without major organ involvement. The clinical presentation and histopathology findings of our cases support that Degos-like lesions may not be a specific entity but can be considered as a unique clinical pattern expressed in patients with CTDs.
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DOI: 10.2147/CCID.S230081
PubMed: 31807047
PubMed Central: 6848981
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Cosmet Investig Dermatol</journal-id><journal-id journal-id-type="iso-abbrev">Clin Cosmet Investig Dermatol</journal-id><journal-id journal-id-type="publisher-id">CCID</journal-id><journal-id journal-id-type="pmc">ccid</journal-id><journal-title-group><journal-title>Clinical, Cosmetic and Investigational Dermatology</journal-title></journal-title-group><issn pub-type="epub">1178-7015</issn><publisher><publisher-name>Dove</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31807047</article-id><article-id pub-id-type="pmc">6848981</article-id><article-id pub-id-type="publisher-id">230081</article-id><article-id pub-id-type="doi">10.2147/CCID.S230081</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Series</subject></subj-group></article-categories><title-group><article-title>Degos-Like Lesions In Association With Connective Tissue Diseases: A Report Of Three Cases And Literature Review</article-title><alt-title alt-title-type="running-authors">Stavorn and Chanprapaph</alt-title><alt-title alt-title-type="running-title">Stavorn and Chanprapaph</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Stavorn</surname><given-names>Taptim</given-names></name><xref ref-type="aff" rid="AFF0001">1</xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0001-7931-3816</contrib-id><name><surname>Chanprapaph</surname><given-names>Kumutnart</given-names></name><xref ref-type="corresp" rid="AN0001"></xref><xref ref-type="aff" rid="AFF0001">1</xref></contrib><aff id="AFF0001"><label>1</label><institution>Division of Dermatology, Department of Medicine, Ramathibodi Hospital, Mahidol University</institution>,<addr-line>Bangkok</addr-line>,<country>Thailand</country></aff></contrib-group><author-notes><corresp id="AN0001">Correspondence: Kumutnart Chanprapaph <institution>Division of Dermatology, Department of Medicine, Ramathibodi Hospital, Mahidol University</institution>, <addr-line>270 Rama VI Road, Ratchatewi</addr-line>, <addr-line>Bangkok</addr-line><addr-line>10400</addr-line>, <country>Thailand</country><phone>Tel +66 2 201 1141</phone><fax>Fax +66 2 201 1211</fax> Email kumutnartp@hotmail.com</corresp></author-notes><pub-date pub-type="epub"><day>07</day><month>11</month><year>2019</year></pub-date><pub-date pub-type="collection"><year>2019</year></pub-date><volume>12</volume><fpage>815</fpage><lpage>822</lpage><history><date date-type="received"><day>06</day><month>9</month><year>2019</year></date><date date-type="accepted"><day>26</day><month>10</month><year>2019</year></date></history><permissions><copyright-statement>© 2019 Stavorn and Chanprapaph.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder>Stavorn and Chanprapaph.</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/"><license-p>This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at <ext-link ext-link-type="uri" xlink:href="https://www.dovepress.com/terms.php">https://www.dovepress.com/terms.php</ext-link> and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0/">http://creativecommons.org/licenses/by-nc/3.0/</ext-link>). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (<ext-link ext-link-type="uri" xlink:href="https://www.dovepress.com/terms.php">https://www.dovepress.com/terms.php</ext-link>).</license-p></license></permissions><abstract><title>Abstract</title><p>Degos disease is characterized by atrophic porcelain-white papules with peripheral erythema. Degos-like lesions have been reported in association with several connective tissue diseases (CTDs), mostly systemic lupus erythematosus (SLE), and rarely in dermatomyositis and systemic sclerosis. Herein, we report three cases of Degos-like lesions in CTDs. Two cases had Degos-like lesions linked to dermatomyositis. Both cases presented with severe inflammatory myopathy without pathognomonic cutaneous signs for dermatomyositis and lacked myositis-specific autoantibodies. Our third case, to our knowledge, is the first case of Degos-like lesions in association with overlapping systemic sclerosis and SLE without major organ involvement. The clinical presentation and histopathology findings of our cases support that Degos-like lesions may not be a specific entity but can be considered as a unique clinical pattern expressed in patients with CTDs.</p></abstract><kwd-group kwd-group-type="author"><title>Keywords</title><kwd>degos-like lesions</kwd><kwd>degos disease</kwd><kwd>dermatomyositis</kwd><kwd>systemic sclerosis</kwd><kwd>systemic lupus erythematosus</kwd><kwd>connective tissue diseases</kwd></kwd-group><counts><fig-count count="3"></fig-count><table-count count="1"></table-count><ref-count count="19"></ref-count><page-count count="8"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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