Immunoadsorption and autologous transplantation for life-threatening primary antiphospholipid syndrome
Identifieur interne : 000270 ( Pmc/Curation ); précédent : 000269; suivant : 000271Immunoadsorption and autologous transplantation for life-threatening primary antiphospholipid syndrome
Auteurs : Anne Angelillo-Scherrer ; Behrouz Mansouri Taleghani ; Frauke Förger ; Gabriela M. Baerlocher ; Thomas Pabst ; Alexander Pöllinger ; Yara Banz ; Thomas Geiser [Suisse] ; Johanna A. Kremer Hovinga ; Alicia RovSource :
- Blood Advances [ 2473-9529 ] ; 2019.
Abstract
Reduction of APL antibodies by immunoadsorption may be a lifesaving therapy for the management of DAH with high titer of APL antibodies. Autologous HSCT may be a valid treatment option in patients with primary APS and no response to standard immunosuppressive therapy.
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DOI: 10.1182/bloodadvances.2019000465
PubMed: 31506284
PubMed Central: 6737408
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Anne Angelillo-Scherrer<affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff3">Department of Rheumatology, Immunology, Allergology, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation><affiliation><nlm:aff id="aff4">Department of Medical Oncology, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff5">Department of Diagnostic, Interventional and Pediatrics Radiology, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation>Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immunoadsorption and autologous transplantation for life-threatening primary antiphospholipid syndrome</title><author><name sortKey="Angelillo Scherrer, Anne" sort="Angelillo Scherrer, Anne" uniqKey="Angelillo Scherrer A" first="Anne" last="Angelillo-Scherrer">Anne Angelillo-Scherrer</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation></author><author><name sortKey="Mansouri Taleghani, Behrouz" sort="Mansouri Taleghani, Behrouz" uniqKey="Mansouri Taleghani B" first="Behrouz" last="Mansouri Taleghani">Behrouz Mansouri Taleghani</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Forger, Frauke" sort="Forger, Frauke" uniqKey="Forger F" first="Frauke" last="Förger">Frauke Förger</name><affiliation><nlm:aff id="aff3">Department of Rheumatology, Immunology, Allergology, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Baerlocher, Gabriela M" sort="Baerlocher, Gabriela M" uniqKey="Baerlocher G" first="Gabriela M." last="Baerlocher">Gabriela M. Baerlocher</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation></author><author><name sortKey="Pabst, Thomas" sort="Pabst, Thomas" uniqKey="Pabst T" first="Thomas" last="Pabst">Thomas Pabst</name><affiliation><nlm:aff id="aff4">Department of Medical Oncology, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Pollinger, Alexander" sort="Pollinger, Alexander" uniqKey="Pollinger A" first="Alexander" last="Pöllinger">Alexander Pöllinger</name><affiliation><nlm:aff id="aff5">Department of Diagnostic, Interventional and Pediatrics Radiology, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Banz, Yara" sort="Banz, Yara" uniqKey="Banz Y" first="Yara" last="Banz">Yara Banz</name><affiliation><nlm:aff wicri:cut=", and" id="aff6">Institute of Pathology</nlm:aff></affiliation></author><author><name sortKey="Geiser, Thomas" sort="Geiser, Thomas" uniqKey="Geiser T" first="Thomas" last="Geiser">Thomas Geiser</name><affiliation wicri:level="1"><nlm:aff id="aff7">Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern</wicri:regionArea></affiliation></author><author><name sortKey="Kremer Hovinga, Johanna A" sort="Kremer Hovinga, Johanna A" uniqKey="Kremer Hovinga J" first="Johanna A." last="Kremer Hovinga">Johanna A. Kremer Hovinga</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation></author><author><name sortKey="Rov, Alicia" sort="Rov, Alicia" uniqKey="Rov A" first="Alicia" last="Rov">Alicia Rov</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">31506284</idno><idno type="pmc">6737408</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737408</idno><idno type="RBID">PMC:6737408</idno><idno type="doi">10.1182/bloodadvances.2019000465</idno><date when="2019">2019</date><idno type="wicri:Area/Pmc/Corpus">000270</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000270</idno><idno type="wicri:Area/Pmc/Curation">000270</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000270</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Immunoadsorption and autologous transplantation for life-threatening primary antiphospholipid syndrome</title><author><name sortKey="Angelillo Scherrer, Anne" sort="Angelillo Scherrer, Anne" uniqKey="Angelillo Scherrer A" first="Anne" last="Angelillo-Scherrer">Anne Angelillo-Scherrer</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation></author><author><name sortKey="Mansouri Taleghani, Behrouz" sort="Mansouri Taleghani, Behrouz" uniqKey="Mansouri Taleghani B" first="Behrouz" last="Mansouri Taleghani">Behrouz Mansouri Taleghani</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Forger, Frauke" sort="Forger, Frauke" uniqKey="Forger F" first="Frauke" last="Förger">Frauke Förger</name><affiliation><nlm:aff id="aff3">Department of Rheumatology, Immunology, Allergology, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Baerlocher, Gabriela M" sort="Baerlocher, Gabriela M" uniqKey="Baerlocher G" first="Gabriela M." last="Baerlocher">Gabriela M. Baerlocher</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation></author><author><name sortKey="Pabst, Thomas" sort="Pabst, Thomas" uniqKey="Pabst T" first="Thomas" last="Pabst">Thomas Pabst</name><affiliation><nlm:aff id="aff4">Department of Medical Oncology, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Pollinger, Alexander" sort="Pollinger, Alexander" uniqKey="Pollinger A" first="Alexander" last="Pöllinger">Alexander Pöllinger</name><affiliation><nlm:aff id="aff5">Department of Diagnostic, Interventional and Pediatrics Radiology, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author><author><name sortKey="Banz, Yara" sort="Banz, Yara" uniqKey="Banz Y" first="Yara" last="Banz">Yara Banz</name><affiliation><nlm:aff wicri:cut=", and" id="aff6">Institute of Pathology</nlm:aff></affiliation></author><author><name sortKey="Geiser, Thomas" sort="Geiser, Thomas" uniqKey="Geiser T" first="Thomas" last="Geiser">Thomas Geiser</name><affiliation wicri:level="1"><nlm:aff id="aff7">Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern</wicri:regionArea></affiliation></author><author><name sortKey="Kremer Hovinga, Johanna A" sort="Kremer Hovinga, Johanna A" uniqKey="Kremer Hovinga J" first="Johanna A." last="Kremer Hovinga">Johanna A. Kremer Hovinga</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation><affiliation><nlm:aff id="aff2">Department for BioMedical Research,</nlm:aff></affiliation></author><author><name sortKey="Rov, Alicia" sort="Rov, Alicia" uniqKey="Rov A" first="Alicia" last="Rov">Alicia Rov</name><affiliation><nlm:aff id="aff1">Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</nlm:aff><wicri:noCountry code="subfield">Bern University Hospital</wicri:noCountry></affiliation></author></analytic><series><title level="j">Blood Advances</title><idno type="ISSN">2473-9529</idno><idno type="eISSN">2473-9537</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Key Points</title><p><list list-type="bullet"><list-item><p>Reduction of APL antibodies by immunoadsorption may be a lifesaving therapy for the management of DAH with high titer of APL antibodies.</p></list-item><list-item><p>Autologous HSCT may be a valid treatment option in patients with primary APS and no response to standard immunosuppressive therapy.</p></list-item></list></p></div></front></TEI><pmc article-type="case-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Blood Adv</journal-id><journal-id journal-id-type="iso-abbrev">Blood Adv</journal-id><journal-id journal-id-type="hwp">bloodoa</journal-id><journal-id journal-id-type="pmc">Blood Adv</journal-id><journal-id journal-id-type="publisher-id">Blood Advances</journal-id><journal-title-group><journal-title>Blood Advances</journal-title></journal-title-group><issn pub-type="ppub">2473-9529</issn><issn pub-type="epub">2473-9537</issn><publisher><publisher-name>American Society of Hematology</publisher-name><publisher-loc>Washington, DC</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">31506284</article-id><article-id pub-id-type="pmc">6737408</article-id><article-id pub-id-type="publisher-id">2019/ADV2019000465</article-id><article-id pub-id-type="doi">10.1182/bloodadvances.2019000465</article-id><article-categories><subj-group subj-group-type="hwp-journal-coll"><subject>1</subject><subject>20</subject><subject>29</subject><subject>31</subject></subj-group><subj-group subj-group-type="heading"><subject>Exceptional Case Report</subject></subj-group></article-categories><title-group><article-title>Immunoadsorption and autologous transplantation for life-threatening primary antiphospholipid syndrome</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0003-2872-4863</contrib-id><name><surname>Angelillo-Scherrer</surname><given-names>Anne</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Mansouri Taleghani</surname><given-names>Behrouz</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Förger</surname><given-names>Frauke</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Baerlocher</surname><given-names>Gabriela M.</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Pabst</surname><given-names>Thomas</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Pöllinger</surname><given-names>Alexander</given-names></name><xref ref-type="aff" rid="aff5">5</xref></contrib><contrib contrib-type="author"><name><surname>Banz</surname><given-names>Yara</given-names></name><xref ref-type="aff" rid="aff6">6</xref></contrib><contrib contrib-type="author"><name><surname>Geiser</surname><given-names>Thomas</given-names></name><xref ref-type="aff" rid="aff7">7</xref></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid" authenticated="false">http://orcid.org/0000-0002-1300-7135</contrib-id><name><surname>Kremer Hovinga</surname><given-names>Johanna A.</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Rovó</surname><given-names>Alicia</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><aff id="aff1"><label>1</label>Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital,</aff><aff id="aff2"><label>2</label>Department for BioMedical Research,</aff><aff id="aff3"><label>3</label>Department of Rheumatology, Immunology, Allergology, Inselspital, Bern University Hospital,</aff><aff id="aff4"><label>4</label>Department of Medical Oncology, Inselspital, Bern University Hospital,</aff><aff id="aff5"><label>5</label>Department of Diagnostic, Interventional and Pediatrics Radiology, Bern University Hospital,</aff><aff id="aff6"><label>6</label>Institute of Pathology, and</aff><aff id="aff7"><label>7</label>Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland</aff></contrib-group><pub-date pub-type="collection"><day>10</day><month>9</month><year>2019</year></pub-date><pub-date pub-type="epub"><day>10</day><month>9</month><year>2019</year></pub-date><pub-date pub-type="pmc-release"><day>10</day><month>9</month><year>2019</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>3</volume><issue>17</issue><fpage>2664</fpage><lpage>2667</lpage><history><date date-type="received"><day>19</day><month>5</month><year>2019</year></date><date date-type="accepted"><day>23</day><month>7</month><year>2019</year></date></history><permissions><copyright-statement>© 2019 by The American Society of Hematology</copyright-statement><copyright-year>2019</copyright-year><ali:free_to_read></ali:free_to_read></permissions><self-uri xlink:title="pdf" xlink:href="advancesADV2019000465.pdf"></self-uri><abstract abstract-type="executive-summary"><title>Key Points</title><p><list list-type="bullet"><list-item><p>Reduction of APL antibodies by immunoadsorption may be a lifesaving therapy for the management of DAH with high titer of APL antibodies.</p></list-item><list-item><p>Autologous HSCT may be a valid treatment option in patients with primary APS and no response to standard immunosuppressive therapy.</p></list-item></list></p></abstract><counts><page-count count="4"></page-count></counts><custom-meta-group><custom-meta><meta-name>access</meta-name><meta-value>free</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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