Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
Identifieur interne : 000128 ( Pmc/Checkpoint ); précédent : 000127; suivant : 000129Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro
Auteurs : Jia Liu [République populaire de Chine] ; Ruiyuan Cao [République populaire de Chine] ; Mingyue Xu [République populaire de Chine] ; Xi Wang [République populaire de Chine] ; Huanyu Zhang [République populaire de Chine] ; Hengrui Hu [République populaire de Chine] ; Yufeng Li [République populaire de Chine] ; Zhihong Hu [République populaire de Chine] ; Wu Zhong [République populaire de Chine] ; Manli Wang [République populaire de Chine]Source :
- Cell Discovery [ 2056-5968 ] ; 2020.
Url:
DOI: 10.1038/s41421-020-0156-0
PubMed: 32194981
PubMed Central: 7078228
Affiliations:
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Cell Discov</journal-id><journal-id journal-id-type="iso-abbrev">Cell Discov</journal-id><journal-title-group><journal-title>Cell Discovery</journal-title></journal-title-group><issn pub-type="epub">2056-5968</issn><publisher><publisher-name>Springer Singapore</publisher-name><publisher-loc>Singapore</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">32194981</article-id><article-id pub-id-type="pmc">7078228</article-id><article-id pub-id-type="publisher-id">156</article-id><article-id pub-id-type="doi">10.1038/s41421-020-0156-0</article-id><article-categories><subj-group subj-group-type="heading"><subject>Correspondence</subject></subj-group></article-categories><title-group><article-title>Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name><surname>Liu</surname><given-names>Jia</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Cao</surname><given-names>Ruiyuan</given-names></name><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Xu</surname><given-names>Mingyue</given-names></name><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Xi</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Zhang</surname><given-names>Huanyu</given-names></name><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Hu</surname><given-names>Hengrui</given-names></name><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Yufeng</given-names></name><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff3">3</xref></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">http://orcid.org/0000-0002-1560-0928</contrib-id><name><surname>Hu</surname><given-names>Zhihong</given-names></name><address><email>huzh@wh.iov.cn</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Zhong</surname><given-names>Wu</given-names></name><address><email>zhongwu@bmi.ac.cn</email></address><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Wang</surname><given-names>Manli</given-names></name><address><email>wangml@wh.iov.cn</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><aff id="Aff1"><label>1</label><institution-wrap><institution-id institution-id-type="ISNI">0000000119573309</institution-id><institution-id institution-id-type="GRID">grid.9227.e</institution-id><institution>State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science,</institution><institution>Chinese Academy of Sciences,</institution></institution-wrap>430071 Wuhan, China</aff><aff id="Aff2"><label>2</label><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1803 4911</institution-id><institution-id institution-id-type="GRID">grid.410740.6</institution-id><institution>National Engineering Research Center for the Emergency Drug,</institution><institution>Beijing Institute of Pharmacology and Toxicology,</institution></institution-wrap>100850 Beijing, China</aff><aff id="Aff3"><label>3</label><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1797 8419</institution-id><institution-id institution-id-type="GRID">grid.410726.6</institution-id><institution>University of the Chinese Academy of Sciences,</institution></institution-wrap>100049 Beijing, China</aff></contrib-group><pub-date pub-type="epub"><day>18</day><month>3</month><year>2020</year></pub-date><pub-date pub-type="pmc-release"><day>18</day><month>3</month><year>2020</year></pub-date><pub-date pub-type="collection"><year>2020</year></pub-date><volume>6</volume><elocation-id>16</elocation-id><history><date date-type="received"><day>24</day><month>2</month><year>2020</year></date><date date-type="accepted"><day>4</day><month>3</month><year>2020</year></date></history><permissions><copyright-statement>© The Author(s) 2020</copyright-statement><license license-type="OpenAccess"><license-p><bold>Open Access</bold> This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>.</license-p></license></permissions><kwd-group kwd-group-type="npg-subject"><title>Subject terms</title><kwd>Autophagy</kwd><kwd>Transcription</kwd></kwd-group><funding-group><award-group><funding-source><institution>the National Natural Science Foundation of China (grant no. 31621061 to Z.H.), and the Hubei Science and Technology Project (2020FCA003 to Z.H.).</institution></funding-source></award-group></funding-group><funding-group><award-group><funding-source><institution>the National Science and Technology Major Projects for “Major New Drugs Innovation and Development” (grant no. 2018ZX09711003 to W.Z.)</institution></funding-source></award-group></funding-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© The Author(s) 2020</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Liu, Jia" sort="Liu, Jia" uniqKey="Liu J" first="Jia" last="Liu">Jia Liu</name></noRegion><name sortKey="Cao, Ruiyuan" sort="Cao, Ruiyuan" uniqKey="Cao R" first="Ruiyuan" last="Cao">Ruiyuan Cao</name><name sortKey="Hu, Hengrui" sort="Hu, Hengrui" uniqKey="Hu H" first="Hengrui" last="Hu">Hengrui Hu</name><name sortKey="Hu, Hengrui" sort="Hu, Hengrui" uniqKey="Hu H" first="Hengrui" last="Hu">Hengrui Hu</name><name sortKey="Hu, Zhihong" sort="Hu, Zhihong" uniqKey="Hu Z" first="Zhihong" last="Hu">Zhihong Hu</name><name sortKey="Li, Yufeng" sort="Li, Yufeng" uniqKey="Li Y" first="Yufeng" last="Li">Yufeng Li</name><name sortKey="Li, Yufeng" sort="Li, Yufeng" uniqKey="Li Y" first="Yufeng" last="Li">Yufeng Li</name><name sortKey="Wang, Manli" sort="Wang, Manli" uniqKey="Wang M" first="Manli" last="Wang">Manli Wang</name><name sortKey="Wang, Xi" sort="Wang, Xi" uniqKey="Wang X" first="Xi" last="Wang">Xi Wang</name><name sortKey="Xu, Mingyue" sort="Xu, Mingyue" uniqKey="Xu M" first="Mingyue" last="Xu">Mingyue Xu</name><name sortKey="Xu, Mingyue" sort="Xu, Mingyue" uniqKey="Xu M" first="Mingyue" last="Xu">Mingyue Xu</name><name sortKey="Zhang, Huanyu" sort="Zhang, Huanyu" uniqKey="Zhang H" first="Huanyu" last="Zhang">Huanyu Zhang</name><name sortKey="Zhang, Huanyu" sort="Zhang, Huanyu" uniqKey="Zhang H" first="Huanyu" last="Zhang">Huanyu Zhang</name><name sortKey="Zhong, Wu" sort="Zhong, Wu" uniqKey="Zhong W" first="Wu" last="Zhong">Wu Zhong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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