Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGG : studies on cultured glioma cells
Identifieur interne : 000071 ( PascalFrancis/Curation ); précédent : 000070; suivant : 000072Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGG : studies on cultured glioma cells
Auteurs : J. Capala [Suède] ; J. CarlssonSource :
- International journal of radiation biology [ 0955-3002 ] ; 1991.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Radiobiologie.
English descriptors
- KwdEn :
Abstract
Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas. Radiation effects of [131I]EGF on human malignant glioma cells growing as monolayers were analysed in this study. The cells were, in all cases, incubated for 25 min with about 350 kBq/ml [131I]EGF, which gave a total binding of 3-2-3-5 kBq/105 cells
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I]EGG : studies on cultured glioma cells</title>
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<author><name sortKey="Carlsson, J" sort="Carlsson, J" uniqKey="Carlsson J" first="J." last="Carlsson">J. Carlsson</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Influence of chloroquine and lidocaine on retention and cytotoxic effects of [<sup>131</sup>
I]EGG : studies on cultured glioma cells</title>
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<term>Tumor cell</term>
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<term>Chloroquine</term>
<term>Lidocaïne</term>
<term>Radiothérapie</term>
<term>Radioisotope</term>
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<term>Ciblage</term>
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<front><div type="abstract" xml:lang="en">Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas. Radiation effects of [<sup>131</sup>
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