ChloroquineV1, PascalFrancis, Checkpoint, bibRecord, 000062

Idiopathic pulmonary fibrosis in infants : good prognosis with conservative management

Identifieur interne : 000062 ( PascalFrancis/Checkpoint ); précédent : 000061; suivant : 000063

Idiopathic pulmonary fibrosis in infants : good prognosis with conservative management

Auteurs : D. Hacking [Australie] ; R. Smyth [Royaume-Uni] ; N. Shaw [Royaume-Uni] ; G. Kokia [Royaume-Uni] ; H. Carty [Royaume-Uni] ; D. Heaf [Royaume-Uni]

Source :

Archives of disease in childhood [ 0003-9888 ] ; 2000.

RBID : Pascal:00-0386276

Descripteurs français

Pascal (Inist)
- Fibrose diffuse interstitielle poumon Hamman Rich, Idiopathique, Pronostic, Long terme, Prednisolone, Antiinflammatoire, Immunodépresseur, Chimiothérapie, Traitement, Etude cas, Nourrisson, Enfant, Corticostéroïde.
Wicri :
- topic : Enfant.

English descriptors

KwdEn :
- Antiinflammatory agent, Case study, Chemotherapy, Child, Corticosteroid, Hamman Rich interstitial pulmonary fibrosis, Idiopathic, Immunosuppressive agent, Infant, Long term, Prednisolone, Prognosis, Treatment.

Abstract

Background-Pulmonary interstitial fibrosis in children is a disease of unknown aetiology, usually associated with a poor prognosis. Methods-In this case series we describe 11 children presenting over a 10 year period, managed conservatively and associated with a good prognosis. Results-In six, symptoms were present from birth and 10 had symptoms at or before 3 months. Diagnosis was made using chest computed tomography and percutaneous lung biopsy. All patients were treated with oral prednisolone. In five no steroid response was noted. One patient responded to hydroxychloroquine. Home oxygen was required in five patients. At follow up all patients are alive at a median age of 6 years (range 1 to 12 years). The two recently diagnosed children have significant symptoms, seven have dyspnoea on exercise, and two are symptom free. Conclusion-The good prognosis seen in these patients is different to previous case reports, indicating a greater than 50% mortality.

Affiliations:

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Pascal:00-0386276

Le document en format XML

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<tree><country name="Australie"><region name="Victoria (État)"><name sortKey="Hacking, D" sort="Hacking, D" uniqKey="Hacking D" first="D." last="Hacking">D. Hacking</name>
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</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Smyth, R" sort="Smyth, R" uniqKey="Smyth R" first="R." last="Smyth">R. Smyth</name>
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<name sortKey="Carty, H" sort="Carty, H" uniqKey="Carty H" first="H." last="Carty">H. Carty</name>
<name sortKey="Heaf, D" sort="Heaf, D" uniqKey="Heaf D" first="D." last="Heaf">D. Heaf</name>
<name sortKey="Kokia, G" sort="Kokia, G" uniqKey="Kokia G" first="G." last="Kokia">G. Kokia</name>
<name sortKey="Shaw, N" sort="Shaw, N" uniqKey="Shaw N" first="N." last="Shaw">N. Shaw</name>
</country>
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</affiliations>
</record>

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   |clé=     Pascal:00-0386276
   |texte=   Idiopathic pulmonary fibrosis in infants : good prognosis with conservative management
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This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

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Serveur d'exploration Chloroquine

Idiopathic pulmonary fibrosis in infants : good prognosis with conservative management

Idiopathic pulmonary fibrosis in infants : good prognosis with conservative management

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