ChloroquineV1, PascalFrancis, Checkpoint, bibRecord, 000016

Treatment Approaches to Juvenile Dermatomyositis (JDM) Across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey

Identifieur interne : 000016 ( PascalFrancis/Checkpoint ); précédent : 000015; suivant : 000017

Treatment Approaches to Juvenile Dermatomyositis (JDM) Across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey

Auteurs : Elizabeth Stringer [Canada, États-Unis, Royaume-Uni] ; John Bohnsack ; Suzanne L. Bowyer ; Thomas A. Griffin ; Adam M. Huber ; Bianca Lang ; Carol B. Lindsley ; Sylvia Ota ; Clarissa Pilkington ; Ann M. Reed ; Rosie Scuccimarri ; Brian M. Feldman

Source :

Journal of rheumatology [ 0315-162X ] ; 2010.

RBID : Pascal:10-0446161

Descripteurs français

Pascal (Inist)
- Traitement, Voie abord, Dermatomyosite, Adolescent, Amérique du Nord, Enfant, Arthrite, Rhumatologie, Enquête, Pédiatrie, Myosite.
Wicri :
- topic : Enfant, Pédiatrie.

English descriptors

KwdEn :
- Adolescent, Arthritis, Child, Dermatomyositis, Myositis, North America, Pediatrics, Rheumatology, Surgical approach, Survey, Treatment.

Abstract

Objective. There are a number of different approaches to the initial treatment of juvenile dermatomyositis (JDM). We assessed the therapeutic approaches of North American pediatric rheumatologists to inform future studies of therapy in JDM. Methods. A survey describing clinical cases of JDM was sent to pediatric rheumatologists. The cases described children with varying severity of typical disease, disease with atypical features, or refractory disease. Three open-ended questions were asked following each case: (1) What additional investigations would you order; (2) What medicine(s) would you start (dose, route, frequency, adjustment over time); and (3) What nonmedication treatment(s) would you start. Results. The response rate was 84% (141/167). For typical cases of JDM, regardless of severity, almost all respondents used corticosteroids and another medication, methotrexate (MTX) being the most commonly used. The route and pattern of corticosteroid administration was variable. Intravenous immunoglobulin (IVIG) was used more frequently for more severe disease, for refractory disease, and for prominent cutaneous disease. Hydroxychloroquine was often used in milder cases and cases principally characterized by rash. Cyclophosphamide was reserved for ulcerative disease and JDM complicated by lung disease. Conclusion. For the majority of North American pediatric rheumatologists, corticosteroids and MTX appear to be the standard of care for typical cases of JDM. There is variability, however, in the route of administration of corticosteroids and use of IVIG and hydroxychloroquine.

Affiliations:

Canada, Royaume-Uni, États-Unis
Angleterre, Grand Londres, Indiana, Kansas, Minnesota, Ohio, Utah
Londres

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Pascal:10-0446161

Le document en format XML

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<series><title level="j" type="main">Journal of rheumatology</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Arthritis</term>
<term>Child</term>
<term>Dermatomyositis</term>
<term>Myositis</term>
<term>North America</term>
<term>Pediatrics</term>
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<term>Voie abord</term>
<term>Dermatomyosite</term>
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<term>Enfant</term>
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<front><div type="abstract" xml:lang="en">Objective. There are a number of different approaches to the initial treatment of juvenile dermatomyositis (JDM). We assessed the therapeutic approaches of North American pediatric rheumatologists to inform future studies of therapy in JDM. Methods. A survey describing clinical cases of JDM was sent to pediatric rheumatologists. The cases described children with varying severity of typical disease, disease with atypical features, or refractory disease. Three open-ended questions were asked following each case: (1) What additional investigations would you order; (2) What medicine(s) would you start (dose, route, frequency, adjustment over time); and (3) What nonmedication treatment(s) would you start. Results. The response rate was 84% (141/167). For typical cases of JDM, regardless of severity, almost all respondents used corticosteroids and another medication, methotrexate (MTX) being the most commonly used. The route and pattern of corticosteroid administration was variable. Intravenous immunoglobulin (IVIG) was used more frequently for more severe disease, for refractory disease, and for prominent cutaneous disease. Hydroxychloroquine was often used in milder cases and cases principally characterized by rash. Cyclophosphamide was reserved for ulcerative disease and JDM complicated by lung disease. Conclusion. For the majority of North American pediatric rheumatologists, corticosteroids and MTX appear to be the standard of care for typical cases of JDM. There is variability, however, in the route of administration of corticosteroids and use of IVIG and hydroxychloroquine.</div>
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<fC03 i1="05" i2="X" l="SPA"><s0>America del norte</s0>
<s2>NG</s2>
<s5>13</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Enfant</s0>
<s5>14</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Child</s0>
<s5>14</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Niño</s0>
<s5>14</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Arthrite</s0>
<s5>15</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Arthritis</s0>
<s5>15</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Artritis</s0>
<s5>15</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Rhumatologie</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Rheumatology</s0>
<s5>16</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Reumatología</s0>
<s5>16</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Enquête</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Survey</s0>
<s5>17</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Encuesta</s0>
<s5>17</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Pédiatrie</s0>
<s5>18</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Pediatrics</s0>
<s5>18</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Pediatría</s0>
<s5>18</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Myosite</s0>
<s5>19</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Myositis</s0>
<s5>19</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Miositis</s0>
<s5>19</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Amérique</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>America</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Maladie autoimmune</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Autoimmune disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Enfermedad autoinmune</s0>
<s5>37</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Maladie de système</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Systemic disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Enfermedad sistémica</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Pathologie du muscle strié</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Striated muscle disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Músculo estriado patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Pathologie de la peau</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Skin disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Piel patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Pathologie du  tissu conjonctif</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Connective tissue disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Tejido conjuntivo patología</s0>
<s5>41</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>42</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>42</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>42</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Pathologie du système ostéoarticulaire</s0>
<s5>43</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Diseases of the osteoarticular system</s0>
<s5>43</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Sistema osteoarticular patología</s0>
<s5>43</s5>
</fC07>
<fN21><s1>291</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
<affiliations><list><country><li>Canada</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Grand Londres</li>
<li>Indiana</li>
<li>Kansas</li>
<li>Minnesota</li>
<li>Ohio</li>
<li>Utah</li>
</region>
<settlement><li>Londres</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Bohnsack, John" sort="Bohnsack, John" uniqKey="Bohnsack J" first="John" last="Bohnsack">John Bohnsack</name>
<name sortKey="Bowyer, Suzanne L" sort="Bowyer, Suzanne L" uniqKey="Bowyer S" first="Suzanne L." last="Bowyer">Suzanne L. Bowyer</name>
<name sortKey="Feldman, Brian M" sort="Feldman, Brian M" uniqKey="Feldman B" first="Brian M." last="Feldman">Brian M. Feldman</name>
<name sortKey="Griffin, Thomas A" sort="Griffin, Thomas A" uniqKey="Griffin T" first="Thomas A." last="Griffin">Thomas A. Griffin</name>
<name sortKey="Huber, Adam M" sort="Huber, Adam M" uniqKey="Huber A" first="Adam M." last="Huber">Adam M. Huber</name>
<name sortKey="Lang, Bianca" sort="Lang, Bianca" uniqKey="Lang B" first="Bianca" last="Lang">Bianca Lang</name>
<name sortKey="Lindsley, Carol B" sort="Lindsley, Carol B" uniqKey="Lindsley C" first="Carol B." last="Lindsley">Carol B. Lindsley</name>
<name sortKey="Ota, Sylvia" sort="Ota, Sylvia" uniqKey="Ota S" first="Sylvia" last="Ota">Sylvia Ota</name>
<name sortKey="Pilkington, Clarissa" sort="Pilkington, Clarissa" uniqKey="Pilkington C" first="Clarissa" last="Pilkington">Clarissa Pilkington</name>
<name sortKey="Reed, Ann M" sort="Reed, Ann M" uniqKey="Reed A" first="Ann M." last="Reed">Ann M. Reed</name>
<name sortKey="Scuccimarri, Rosie" sort="Scuccimarri, Rosie" uniqKey="Scuccimarri R" first="Rosie" last="Scuccimarri">Rosie Scuccimarri</name>
</noCountry>
<country name="Canada"><noRegion><name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
</noRegion>
<name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
<name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
</country>
<country name="États-Unis"><region name="Utah"><name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
</region>
<name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
<name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
<name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
<name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Stringer, Elizabeth" sort="Stringer, Elizabeth" uniqKey="Stringer E" first="Elizabeth" last="Stringer">Elizabeth Stringer</name>
</region>
</country>
</tree>
</affiliations>
</record>

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   |texte=   Treatment Approaches to Juvenile Dermatomyositis (JDM) Across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey
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This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

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Serveur d'exploration Chloroquine

Treatment Approaches to Juvenile Dermatomyositis (JDM) Across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey

Treatment Approaches to Juvenile Dermatomyositis (JDM) Across North America: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) JDM Treatment Survey

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