ChloroquineV1, Ncbi, Merge, bibRecord, 000248

Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.

Identifieur interne : 000248 ( Ncbi/Merge ); précédent : 000247; suivant : 000249

Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.

Auteurs : Vincent E. Rasamison [Madagascar] ; L Harinantenaina Rakotondraibe ; Carla Slebodnick ; Peggy J. Brodie ; Michel Ratsimbason ; Karen Tendyke ; Yongchun Shen ; Lucien M. Randrianjanaka ; David G I. Kingston

Source :

Organic letters [ 1523-7052 ] ; 2014.

RBID : pubmed:24773558

Descripteurs français

English descriptors

KwdEn :
- Antimalarials (chemistry), Antimalarials (isolation & purification), Antimalarials (pharmacology), Antineoplastic Agents, Phytogenic (chemistry), Antineoplastic Agents, Phytogenic (isolation & purification), Antineoplastic Agents, Phytogenic (pharmacology), Chloroquine (pharmacology), Drug Screening Assays, Antitumor, Humans, Inhibitory Concentration 50, Meliaceae (chemistry), Molecular Structure, Nitrogen (chemistry), Plant Leaves (chemistry), Plasmodium falciparum (drug effects), Triterpenes (chemistry), Triterpenes (isolation & purification), Triterpenes (pharmacology).
MESH :
- chemical , chemistry : Antimalarials, Antineoplastic Agents, Phytogenic, Nitrogen, Triterpenes.
- chemical , isolation & purification : Antimalarials, Antineoplastic Agents, Phytogenic, Triterpenes.
- chemical , pharmacology : Antimalarials, Antineoplastic Agents, Phytogenic, Chloroquine, Triterpenes.
- chemistry : Meliaceae, Plant Leaves.
- drug effects : Plasmodium falciparum.
- Drug Screening Assays, Antitumor, Humans, Inhibitory Concentration 50, Molecular Structure.

Abstract

The new triterpene turranoic acid (1) and the new N-containing nor-triterpene turraenine (2), along with triptocallic acid B (3) and esculentoic acid (4) were isolated from leaves of a Turraea sp. Compounds 1-3 showed weak to moderate in vitro antiplasmodial activity against the chloroquine-resistant Plasmodium falciparum strain FCM29. Compound 1 also displayed weak cytotoxic activity against the nonsmall lung cancer cell line H522-T1 with an IC50 value of 16.4 μM.

DOI: 10.1021/ol500775r
PubMed: 24773558

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 000294
to stream PubMed, to step Curation: 000294
to stream PubMed, to step Checkpoint: 000280

Links to Exploration step

pubmed:24773558

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.</title>
<author><name sortKey="Rasamison, Vincent E" sort="Rasamison, Vincent E" uniqKey="Rasamison V" first="Vincent E" last="Rasamison">Vincent E. Rasamison</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre National d'Application des Recherches Pharmaceutiques B.P , 702, Antananarivo 101, Madagascar.</nlm:affiliation>
<country xml:lang="fr">Madagascar</country>
<wicri:regionArea>Centre National d'Application des Recherches Pharmaceutiques B.P , 702, Antananarivo 101</wicri:regionArea>
<wicri:noRegion>Antananarivo 101</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rakotondraibe, L Harinantenaina" sort="Rakotondraibe, L Harinantenaina" uniqKey="Rakotondraibe L" first="L Harinantenaina" last="Rakotondraibe">L Harinantenaina Rakotondraibe</name>
</author>
<author><name sortKey="Slebodnick, Carla" sort="Slebodnick, Carla" uniqKey="Slebodnick C" first="Carla" last="Slebodnick">Carla Slebodnick</name>
</author>
<author><name sortKey="Brodie, Peggy J" sort="Brodie, Peggy J" uniqKey="Brodie P" first="Peggy J" last="Brodie">Peggy J. Brodie</name>
</author>
<author><name sortKey="Ratsimbason, Michel" sort="Ratsimbason, Michel" uniqKey="Ratsimbason M" first="Michel" last="Ratsimbason">Michel Ratsimbason</name>
</author>
<author><name sortKey="Tendyke, Karen" sort="Tendyke, Karen" uniqKey="Tendyke K" first="Karen" last="Tendyke">Karen Tendyke</name>
</author>
<author><name sortKey="Shen, Yongchun" sort="Shen, Yongchun" uniqKey="Shen Y" first="Yongchun" last="Shen">Yongchun Shen</name>
</author>
<author><name sortKey="Randrianjanaka, Lucien M" sort="Randrianjanaka, Lucien M" uniqKey="Randrianjanaka L" first="Lucien M" last="Randrianjanaka">Lucien M. Randrianjanaka</name>
</author>
<author><name sortKey="Kingston, David G I" sort="Kingston, David G I" uniqKey="Kingston D" first="David G I" last="Kingston">David G I. Kingston</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2014">2014</date>
<idno type="RBID">pubmed:24773558</idno>
<idno type="pmid">24773558</idno>
<idno type="doi">10.1021/ol500775r</idno>
<idno type="wicri:Area/PubMed/Corpus">000294</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000294</idno>
<idno type="wicri:Area/PubMed/Curation">000294</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000294</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000280</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000280</idno>
<idno type="wicri:Area/Ncbi/Merge">000248</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.</title>
<author><name sortKey="Rasamison, Vincent E" sort="Rasamison, Vincent E" uniqKey="Rasamison V" first="Vincent E" last="Rasamison">Vincent E. Rasamison</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre National d'Application des Recherches Pharmaceutiques B.P , 702, Antananarivo 101, Madagascar.</nlm:affiliation>
<country xml:lang="fr">Madagascar</country>
<wicri:regionArea>Centre National d'Application des Recherches Pharmaceutiques B.P , 702, Antananarivo 101</wicri:regionArea>
<wicri:noRegion>Antananarivo 101</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Rakotondraibe, L Harinantenaina" sort="Rakotondraibe, L Harinantenaina" uniqKey="Rakotondraibe L" first="L Harinantenaina" last="Rakotondraibe">L Harinantenaina Rakotondraibe</name>
</author>
<author><name sortKey="Slebodnick, Carla" sort="Slebodnick, Carla" uniqKey="Slebodnick C" first="Carla" last="Slebodnick">Carla Slebodnick</name>
</author>
<author><name sortKey="Brodie, Peggy J" sort="Brodie, Peggy J" uniqKey="Brodie P" first="Peggy J" last="Brodie">Peggy J. Brodie</name>
</author>
<author><name sortKey="Ratsimbason, Michel" sort="Ratsimbason, Michel" uniqKey="Ratsimbason M" first="Michel" last="Ratsimbason">Michel Ratsimbason</name>
</author>
<author><name sortKey="Tendyke, Karen" sort="Tendyke, Karen" uniqKey="Tendyke K" first="Karen" last="Tendyke">Karen Tendyke</name>
</author>
<author><name sortKey="Shen, Yongchun" sort="Shen, Yongchun" uniqKey="Shen Y" first="Yongchun" last="Shen">Yongchun Shen</name>
</author>
<author><name sortKey="Randrianjanaka, Lucien M" sort="Randrianjanaka, Lucien M" uniqKey="Randrianjanaka L" first="Lucien M" last="Randrianjanaka">Lucien M. Randrianjanaka</name>
</author>
<author><name sortKey="Kingston, David G I" sort="Kingston, David G I" uniqKey="Kingston D" first="David G I" last="Kingston">David G I. Kingston</name>
</author>
</analytic>
<series><title level="j">Organic letters</title>
<idno type="eISSN">1523-7052</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antimalarials (chemistry)</term>
<term>Antimalarials (isolation & purification)</term>
<term>Antimalarials (pharmacology)</term>
<term>Antineoplastic Agents, Phytogenic (chemistry)</term>
<term>Antineoplastic Agents, Phytogenic (isolation & purification)</term>
<term>Antineoplastic Agents, Phytogenic (pharmacology)</term>
<term>Chloroquine (pharmacology)</term>
<term>Drug Screening Assays, Antitumor</term>
<term>Humans</term>
<term>Inhibitory Concentration 50</term>
<term>Meliaceae (chemistry)</term>
<term>Molecular Structure</term>
<term>Nitrogen (chemistry)</term>
<term>Plant Leaves (chemistry)</term>
<term>Plasmodium falciparum (drug effects)</term>
<term>Triterpenes (chemistry)</term>
<term>Triterpenes (isolation & purification)</term>
<term>Triterpenes (pharmacology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Antinéoplasiques d'origine végétale ()</term>
<term>Antinéoplasiques d'origine végétale (isolement et purification)</term>
<term>Antinéoplasiques d'origine végétale (pharmacologie)</term>
<term>Antipaludiques ()</term>
<term>Antipaludiques (isolement et purification)</term>
<term>Antipaludiques (pharmacologie)</term>
<term>Azote ()</term>
<term>Chloroquine (pharmacologie)</term>
<term>Concentration inhibitrice 50</term>
<term>Feuilles de plante ()</term>
<term>Humains</term>
<term>Meliaceae ()</term>
<term>Plasmodium falciparum ()</term>
<term>Structure moléculaire</term>
<term>Tests de criblage d'agents antitumoraux</term>
<term>Triterpènes ()</term>
<term>Triterpènes (isolement et purification)</term>
<term>Triterpènes (pharmacologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Antimalarials</term>
<term>Antineoplastic Agents, Phytogenic</term>
<term>Nitrogen</term>
<term>Triterpenes</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Antimalarials</term>
<term>Antineoplastic Agents, Phytogenic</term>
<term>Triterpenes</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antimalarials</term>
<term>Antineoplastic Agents, Phytogenic</term>
<term>Chloroquine</term>
<term>Triterpenes</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Meliaceae</term>
<term>Plant Leaves</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Plasmodium falciparum</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Antinéoplasiques d'origine végétale</term>
<term>Antipaludiques</term>
<term>Triterpènes</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antinéoplasiques d'origine végétale</term>
<term>Antipaludiques</term>
<term>Chloroquine</term>
<term>Triterpènes</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Drug Screening Assays, Antitumor</term>
<term>Humans</term>
<term>Inhibitory Concentration 50</term>
<term>Molecular Structure</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Antinéoplasiques d'origine végétale</term>
<term>Antipaludiques</term>
<term>Azote</term>
<term>Concentration inhibitrice 50</term>
<term>Feuilles de plante</term>
<term>Humains</term>
<term>Meliaceae</term>
<term>Plasmodium falciparum</term>
<term>Structure moléculaire</term>
<term>Tests de criblage d'agents antitumoraux</term>
<term>Triterpènes</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The new triterpene turranoic acid (1) and the new N-containing nor-triterpene turraenine (2), along with triptocallic acid B (3) and esculentoic acid (4) were isolated from leaves of a Turraea sp. Compounds 1-3 showed weak to moderate in vitro antiplasmodial activity against the chloroquine-resistant Plasmodium falciparum strain FCM29. Compound 1 also displayed weak cytotoxic activity against the nonsmall lung cancer cell line H522-T1 with an IC50 value of 16.4 μM. </div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24773558</PMID>
<DateCompleted><Year>2014</Year>
<Month>07</Month>
<Day>21</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1523-7052</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>16</Volume>
<Issue>10</Issue>
<PubDate><Year>2014</Year>
<Month>May</Month>
<Day>16</Day>
</PubDate>
</JournalIssue>
<Title>Organic letters</Title>
<ISOAbbreviation>Org. Lett.</ISOAbbreviation>
</Journal>
<ArticleTitle>Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.</ArticleTitle>
<Pagination><MedlinePgn>2626-9</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1021/ol500775r</ELocationID>
<Abstract><AbstractText>The new triterpene turranoic acid (1) and the new N-containing nor-triterpene turraenine (2), along with triptocallic acid B (3) and esculentoic acid (4) were isolated from leaves of a Turraea sp. Compounds 1-3 showed weak to moderate in vitro antiplasmodial activity against the chloroquine-resistant Plasmodium falciparum strain FCM29. Compound 1 also displayed weak cytotoxic activity against the nonsmall lung cancer cell line H522-T1 with an IC50 value of 16.4 μM. </AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Rasamison</LastName>
<ForeName>Vincent E</ForeName>
<Initials>VE</Initials>
<AffiliationInfo><Affiliation>Centre National d'Application des Recherches Pharmaceutiques B.P , 702, Antananarivo 101, Madagascar.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Rakotondraibe</LastName>
<ForeName>L Harinantenaina</ForeName>
<Initials>LH</Initials>
</Author>
<Author ValidYN="Y"><LastName>Slebodnick</LastName>
<ForeName>Carla</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Brodie</LastName>
<ForeName>Peggy J</ForeName>
<Initials>PJ</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ratsimbason</LastName>
<ForeName>Michel</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>TenDyke</LastName>
<ForeName>Karen</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Shen</LastName>
<ForeName>Yongchun</ForeName>
<Initials>Y</Initials>
</Author>
<Author ValidYN="Y"><LastName>Randrianjanaka</LastName>
<ForeName>Lucien M</ForeName>
<Initials>LM</Initials>
</Author>
<Author ValidYN="Y"><LastName>Kingston</LastName>
<ForeName>David G I</ForeName>
<Initials>DG</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>U01 TW000313</GrantID>
<Acronym>TW</Acronym>
<Agency>FIC NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
<PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>04</Month>
<Day>28</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Org Lett</MedlineTA>
<NlmUniqueID>100890393</NlmUniqueID>
<ISSNLinking>1523-7052</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000962">Antimalarials</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000972">Antineoplastic Agents, Phytogenic</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014315">Triterpenes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C000589441">esculentoic acid</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C000589440">triptocallic acid B</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C000589439">turraenine</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C000589438">turranoic acid</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>886U3H6UFF</RegistryNumber>
<NameOfSubstance UI="D002738">Chloroquine</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>N762921K75</RegistryNumber>
<NameOfSubstance UI="D009584">Nitrogen</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000962" MajorTopicYN="N">Antimalarials</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
<QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000972" MajorTopicYN="N">Antineoplastic Agents, Phytogenic</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
<QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002738" MajorTopicYN="N">Chloroquine</DescriptorName>
<QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004354" MajorTopicYN="N">Drug Screening Assays, Antitumor</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020128" MajorTopicYN="N">Inhibitory Concentration 50</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D029582" MajorTopicYN="N">Meliaceae</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015394" MajorTopicYN="N">Molecular Structure</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009584" MajorTopicYN="N">Nitrogen</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018515" MajorTopicYN="N">Plant Leaves</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010963" MajorTopicYN="N">Plasmodium falciparum</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014315" MajorTopicYN="N">Triterpenes</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
<QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2014</Year>
<Month>4</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2014</Year>
<Month>4</Month>
<Day>30</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2014</Year>
<Month>7</Month>
<Day>22</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">24773558</ArticleId>
<ArticleId IdType="doi">10.1021/ol500775r</ArticleId>
<ArticleId IdType="pmc">PMC4027945</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Planta Med. 2003 Mar;69(3):271-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12677535</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Phytochemistry. 2004 Jul;65(14):2031-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15279968</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Steroids. 2006 Aug;71(8):720-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16765400</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Insect Biochem Physiol. 1997;35(1-2):211-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9131785</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Farmaco Sci. 1971 Dec;26(12):1089-99</Citation>
<ArticleIdList><ArticleId IdType="pubmed">5144291</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Madagascar</li>
</country>
</list>
<tree><noCountry><name sortKey="Brodie, Peggy J" sort="Brodie, Peggy J" uniqKey="Brodie P" first="Peggy J" last="Brodie">Peggy J. Brodie</name>
<name sortKey="Kingston, David G I" sort="Kingston, David G I" uniqKey="Kingston D" first="David G I" last="Kingston">David G I. Kingston</name>
<name sortKey="Rakotondraibe, L Harinantenaina" sort="Rakotondraibe, L Harinantenaina" uniqKey="Rakotondraibe L" first="L Harinantenaina" last="Rakotondraibe">L Harinantenaina Rakotondraibe</name>
<name sortKey="Randrianjanaka, Lucien M" sort="Randrianjanaka, Lucien M" uniqKey="Randrianjanaka L" first="Lucien M" last="Randrianjanaka">Lucien M. Randrianjanaka</name>
<name sortKey="Ratsimbason, Michel" sort="Ratsimbason, Michel" uniqKey="Ratsimbason M" first="Michel" last="Ratsimbason">Michel Ratsimbason</name>
<name sortKey="Shen, Yongchun" sort="Shen, Yongchun" uniqKey="Shen Y" first="Yongchun" last="Shen">Yongchun Shen</name>
<name sortKey="Slebodnick, Carla" sort="Slebodnick, Carla" uniqKey="Slebodnick C" first="Carla" last="Slebodnick">Carla Slebodnick</name>
<name sortKey="Tendyke, Karen" sort="Tendyke, Karen" uniqKey="Tendyke K" first="Karen" last="Tendyke">Karen Tendyke</name>
</noCountry>
<country name="Madagascar"><noRegion><name sortKey="Rasamison, Vincent E" sort="Rasamison, Vincent E" uniqKey="Rasamison V" first="Vincent E" last="Rasamison">Vincent E. Rasamison</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Ncbi/Merge

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000248 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000248 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Ncbi
   |étape=   Merge
   |type=    RBID
   |clé=     pubmed:24773558
   |texte=   Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i   -Sk "pubmed:24773558" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd   \
       | NlmPubMed2Wicri -a ChloroquineV1

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Chloroquine

Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.

Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki