Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by Mycoplasma hyopneumoniae
Identifieur interne : 000B00 ( Ncbi/Curation ); précédent : 000A99; suivant : 000B01Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by Mycoplasma hyopneumoniae
Auteurs : Xia Li [République populaire de Chine] ; Yun-Ke Zhang [République populaire de Chine] ; Bao Yin [République populaire de Chine] ; Jing-Bo Liang [République populaire de Chine] ; Fei Jiang [République populaire de Chine] ; Wen-Xue Wu [République populaire de Chine]Source :
- Infection and Immunity [ 0019-9567 ] ; 2019.
Abstract
IgA plays an important role in mucosal immunity against infectious pathogens; however, the molecular mechanism of IgA secretion in response to infection remains largely unknown, particularly in
Url:
DOI: 10.1128/IAI.00697-19
PubMed: 31611272
PubMed Central: 6921651
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PMC:6921651Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by <named-content content-type="genus-species">Mycoplasma hyopneumoniae</named-content>
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<author><name sortKey="Li, Xia" sort="Li, Xia" uniqKey="Li X" first="Xia" last="Li">Xia Li</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, China Agricultural University, Beijing</wicri:regionArea>
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<author><name sortKey="Zhang, Yun Ke" sort="Zhang, Yun Ke" uniqKey="Zhang Y" first="Yun-Ke" last="Zhang">Yun-Ke Zhang</name>
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<author><name sortKey="Yin, Bao" sort="Yin, Bao" uniqKey="Yin B" first="Bao" last="Yin">Bao Yin</name>
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<author><name sortKey="Liang, Jing Bo" sort="Liang, Jing Bo" uniqKey="Liang J" first="Jing-Bo" last="Liang">Jing-Bo Liang</name>
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<author><name sortKey="Jiang, Fei" sort="Jiang, Fei" uniqKey="Jiang F" first="Fei" last="Jiang">Fei Jiang</name>
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<author><name sortKey="Wu, Wen Xue" sort="Wu, Wen Xue" uniqKey="Wu W" first="Wen-Xue" last="Wu">Wen-Xue Wu</name>
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<series><title level="j">Infection and Immunity</title>
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<front><div type="abstract" xml:lang="en"><p>IgA plays an important role in mucosal immunity against infectious pathogens; however, the molecular mechanism of IgA secretion in response to infection remains largely unknown, particularly in <named-content content-type="genus-species">Mycoplasma</named-content>
spp. In this study, we found that the levels of IgA in the peripheral blood serum, bronchoalveolar lavage fluid, nasal mucosa, trachea, hilar lymph nodes, and lung tissues of pigs increased significantly after infection with <named-content content-type="genus-species">Mycoplasma hyopneumoniae</named-content>
.</p>
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