Life threatening exacerbation in idiopathic pulmonary hemosiderosis salvaged by cyclophosphamide infusion.
Identifieur interne : 000094 ( Ncbi/Curation ); précédent : 000093; suivant : 000095Life threatening exacerbation in idiopathic pulmonary hemosiderosis salvaged by cyclophosphamide infusion.
Auteurs : Rahul Naithani [Inde] ; Jagdish Chandra ; Varinder Singh ; Veerendra Kumar ; N K DubeySource :
- The Indian journal of chest diseases & allied sciences [ 0377-9343 ]
Descripteurs français
- KwdFr :
- MESH :
- administration et posologie : Cyclophosphamide.
- traitement médicamenteux : Hémosidérose, Maladies pulmonaires.
- Enfant, Femelle, Humains, Perfusions veineuses.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Cyclophosphamide.
- drug therapy : Hemosiderosis, Lung Diseases.
- Child, Female, Humans, Infusions, Intravenous.
Abstract
A seven-year-old girl presented with frequent fever, cough and shortness of breath of three months duration. On the basis of her clinical features, peripheral blood and sputum findings, she was diagnosed as a case of idiopathic pulmonary hemosiderosis. After initial stabilisation with steroids and chloroquine, she presented four years later with massive pulmonary hemorrhage and respiratory failure, which responded dramatically to cyclophosphamide infusion. The rare occurrence of pulmonary hemosiderosis and different treatment regimens is discussed.
PubMed: 16970298
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pubmed:16970298Le document en format XML
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<wicri:regionArea>Pulmonary and Critical Care Division, Kalawati Saran Children's Hospital and Lady Hardinge Medical College, New Delhi</wicri:regionArea>
<wicri:noRegion>New Delhi</wicri:noRegion>
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<author><name sortKey="Chandra, Jagdish" sort="Chandra, Jagdish" uniqKey="Chandra J" first="Jagdish" last="Chandra">Jagdish Chandra</name>
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<author><name sortKey="Singh, Varinder" sort="Singh, Varinder" uniqKey="Singh V" first="Varinder" last="Singh">Varinder Singh</name>
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<author><name sortKey="Kumar, Veerendra" sort="Kumar, Veerendra" uniqKey="Kumar V" first="Veerendra" last="Kumar">Veerendra Kumar</name>
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<author><name sortKey="Dubey, N K" sort="Dubey, N K" uniqKey="Dubey N" first="N K" last="Dubey">N K Dubey</name>
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<front><div type="abstract" xml:lang="en">A seven-year-old girl presented with frequent fever, cough and shortness of breath of three months duration. On the basis of her clinical features, peripheral blood and sputum findings, she was diagnosed as a case of idiopathic pulmonary hemosiderosis. After initial stabilisation with steroids and chloroquine, she presented four years later with massive pulmonary hemorrhage and respiratory failure, which responded dramatically to cyclophosphamide infusion. The rare occurrence of pulmonary hemosiderosis and different treatment regimens is discussed.</div>
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