Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 24-month open label, extension phase, single-centre trial.
Identifieur interne : 000259 ( Ncbi/Checkpoint ); précédent : 000258; suivant : 000260Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 24-month open label, extension phase, single-centre trial.
Auteurs : J. Gordon [États-Unis] ; U. Udeh ; K. Doobay ; C. Magro ; H. Wildman ; M. Davids ; J N Mersten ; W-T Huang ; S. Lyman ; M K Crow ; R F SpieraSource :
- Clinical and experimental rheumatology [ 0392-856X ]
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Antirhumatismaux (usage thérapeutique), Association de médicaments, Benzamides (usage thérapeutique), Femelle, Glucocorticoïdes (usage thérapeutique), Humains, Hydroxychloroquine (usage thérapeutique), Inhibiteurs de la pompe à protons (usage thérapeutique), Inhibiteurs de protéines kinases (usage thérapeutique), Inhibiteurs des canaux calciques (usage thérapeutique), Mâle, Mésylate d'imatinib, Pipérazines (usage thérapeutique), Pneumopathies interstitielles (traitement médicamenteux), Pneumopathies interstitielles (étiologie), Prednisone (usage thérapeutique), Pyrimidines (usage thérapeutique), Résultat thérapeutique, Sclérodermie diffuse (), Sclérodermie diffuse (traitement médicamenteux), Tests de la fonction respiratoire.
- MESH :
- traitement médicamenteux : Pneumopathies interstitielles, Sclérodermie diffuse.
- usage thérapeutique : Antirhumatismaux, Benzamides, Glucocorticoïdes, Hydroxychloroquine, Inhibiteurs de la pompe à protons, Inhibiteurs de protéines kinases, Inhibiteurs des canaux calciques, Pipérazines, Prednisone, Pyrimidines.
- étiologie : Pneumopathies interstitielles.
- Adulte, Adulte d'âge moyen, Association de médicaments, Femelle, Humains, Mâle, Mésylate d'imatinib, Résultat thérapeutique, Sclérodermie diffuse, Tests de la fonction respiratoire.
English descriptors
- KwdEn :
- Adult, Antirheumatic Agents (therapeutic use), Benzamides (therapeutic use), Calcium Channel Blockers (therapeutic use), Drug Therapy, Combination, Female, Glucocorticoids (therapeutic use), Humans, Hydroxychloroquine (therapeutic use), Imatinib Mesylate, Lung Diseases, Interstitial (drug therapy), Lung Diseases, Interstitial (etiology), Male, Middle Aged, Piperazines (therapeutic use), Prednisone (therapeutic use), Protein Kinase Inhibitors (therapeutic use), Proton Pump Inhibitors (therapeutic use), Pyrimidines (therapeutic use), Respiratory Function Tests, Scleroderma, Diffuse (complications), Scleroderma, Diffuse (drug therapy), Treatment Outcome.
- MESH :
- chemical , therapeutic use : Antirheumatic Agents, Benzamides, Calcium Channel Blockers, Glucocorticoids, Hydroxychloroquine, Piperazines, Prednisone, Protein Kinase Inhibitors, Proton Pump Inhibitors, Pyrimidines.
- complications : Scleroderma, Diffuse.
- drug therapy : Lung Diseases, Interstitial, Scleroderma, Diffuse.
- etiology : Lung Diseases, Interstitial.
- Adult, Drug Therapy, Combination, Female, Humans, Imatinib Mesylate, Male, Middle Aged, Respiratory Function Tests, Treatment Outcome.
Abstract
We aimed to assess the long-term safety and tolerability of imatinib in diffuse cutaneous systemic sclerosis (dcSSc).
PubMed: 25152211
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000284
- to stream PubMed, to step Curation: 000284
- to stream PubMed, to step Checkpoint: 000673
- to stream Ncbi, to step Merge: 000259
- to stream Ncbi, to step Curation: 000259
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pubmed:25152211Le document en format XML
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<affiliation wicri:level="2"><nlm:affiliation>Hospital for Special Surgery, New York, USA. gordonj@hss.edu.</nlm:affiliation>
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<front><div type="abstract" xml:lang="en">We aimed to assess the long-term safety and tolerability of imatinib in diffuse cutaneous systemic sclerosis (dcSSc).</div>
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