Antimicrobial susceptibility of Pneumocystis carinii in culture
Identifieur interne : 003572 ( Main/Merge ); précédent : 003571; suivant : 003573Antimicrobial susceptibility of Pneumocystis carinii in culture
Auteurs : Marilyn S. Bartlett [États-Unis] ; Rosanne Eichholtz [États-Unis] ; James W. Smith [États-Unis]Source :
- Diagnostic Microbiology & Infectious Disease [ 0732-8893 ] ; 1985.
Descripteurs français
- KwdFr :
- Amphotéricine B (pharmacologie), Animaux, Anti-infectieux (pharmacologie), Association médicamenteuse (pharmacologie), Association triméthoprime-sulfaméthoxazole, Chloroquine (pharmacologie), Facteurs temps, Humains, Lignée cellulaire, Lignées consanguines de rats, Miconazole (pharmacologie), Milieux de culture, Métronidazole (pharmacologie), Pentamidine (pharmacologie), Pneumocystis (), Pneumocystis (croissance et développement), Rats, Sulfaméthoxazole (pharmacologie), Triméthoprime (pharmacologie).
- MESH :
- croissance et développement : Pneumocystis.
- pharmacologie : Amphotéricine B, Anti-infectieux, Association médicamenteuse, Chloroquine, Miconazole, Métronidazole, Pentamidine, Sulfaméthoxazole, Triméthoprime.
- Animaux, Association triméthoprime-sulfaméthoxazole, Facteurs temps, Humains, Lignée cellulaire, Lignées consanguines de rats, Milieux de culture, Pneumocystis, Rats.
English descriptors
- KwdEn :
- Amphotericin B (pharmacology), Animals, Anti-Infective Agents (pharmacology), Cell Line, Chloroquine (pharmacology), Culture Media, Drug Combinations (pharmacology), Humans, Metronidazole (pharmacology), Miconazole (pharmacology), Pentamidine (pharmacology), Pneumocystis (drug effects), Pneumocystis (growth & development), Rats, Rats, Inbred Strains, Sulfamethoxazole (pharmacology), Time Factors, Trimethoprim (pharmacology), Trimethoprim, Sulfamethoxazole Drug Combination.
- MESH :
- chemical , pharmacology : Amphotericin B, Anti-Infective Agents, Chloroquine, Drug Combinations, Metronidazole, Miconazole, Pentamidine, Sulfamethoxazole, Trimethoprim.
- drug effects : Pneumocystis.
- growth & development : Pneumocystis.
- Teeft :
- Abnormal liver function, Adverse reactions, Animals, Antimicrobial, Antimicrobial susceptibility, Carinii, Cell Line, Cell culture, Cell cultures, Chloroquine, Culture Media, Culture supernates, Culture system, Culture systems, Cyst, Data point, Good growth, Humans, Immunodeficiency syndrome, Isethionate, Metronidazole, Miconazole, Outgrowth, Outgrowth cultures, Pentamidine, Pentamidine isethionate, Pifer, Pneumocystis, Pneumocystis carinii, Pneumocystis carinii pneumonia, Pneumocystis pneumonia, Preliminary studies, Primary culture, Rats, Rats, Inbred Strains, Sulfamethoxazole, Supernate, Supernate organisms, Thymidine, Thymidine phosphorylase, Time Factors, Trimethoprim sulfamethoxazole, Trimethoprim, Sulfamethoxazole Drug Combination, Trophozoite, Unpublished data.
Abstract
Abstract: Pneumocystiscarinii from infected rats were cultured on infected WI-38 human lung fibroblasts. After cultures were established, medium was replaced by medium containing antimicrobials and supernate organisms counted at specified times. Results show that metronidazole had no effect, amphotericin B suppressed organisms at 5 but not 0.5 μg/ml, and miconazole, chloroquine, trimethoprim-sulfamethoxazole, and pentamidine isethionate suppressed organisms at the concentrations tested.
Url:
DOI: 10.1016/0732-8893(85)90076-8
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Bartlett</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>the Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Eichholtz, Rosanne" sort="Eichholtz, Rosanne" uniqKey="Eichholtz R" first="Rosanne" last="Eichholtz">Rosanne Eichholtz</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>the Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Smith, James W" sort="Smith, James W" uniqKey="Smith J" first="James W." last="Smith">James W. Smith</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>the Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Diagnostic Microbiology & Infectious Disease</title><title level="j" type="abbrev">DMB</title><idno type="ISSN">0732-8893</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1985">1985</date><biblScope unit="volume">3</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="381">381</biblScope><biblScope unit="page" to="387">387</biblScope></imprint><idno type="ISSN">0732-8893</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0732-8893</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amphotericin B (pharmacology)</term><term>Animals</term><term>Anti-Infective Agents (pharmacology)</term><term>Cell Line</term><term>Chloroquine (pharmacology)</term><term>Culture Media</term><term>Drug Combinations (pharmacology)</term><term>Humans</term><term>Metronidazole (pharmacology)</term><term>Miconazole (pharmacology)</term><term>Pentamidine (pharmacology)</term><term>Pneumocystis (drug effects)</term><term>Pneumocystis (growth & development)</term><term>Rats</term><term>Rats, Inbred Strains</term><term>Sulfamethoxazole (pharmacology)</term><term>Time Factors</term><term>Trimethoprim (pharmacology)</term><term>Trimethoprim, Sulfamethoxazole Drug Combination</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Amphotéricine B (pharmacologie)</term><term>Animaux</term><term>Anti-infectieux (pharmacologie)</term><term>Association médicamenteuse (pharmacologie)</term><term>Association triméthoprime-sulfaméthoxazole</term><term>Chloroquine (pharmacologie)</term><term>Facteurs temps</term><term>Humains</term><term>Lignée cellulaire</term><term>Lignées consanguines de rats</term><term>Miconazole (pharmacologie)</term><term>Milieux de culture</term><term>Métronidazole (pharmacologie)</term><term>Pentamidine (pharmacologie)</term><term>Pneumocystis ()</term><term>Pneumocystis (croissance et développement)</term><term>Rats</term><term>Sulfaméthoxazole (pharmacologie)</term><term>Triméthoprime (pharmacologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Amphotericin B</term><term>Anti-Infective Agents</term><term>Chloroquine</term><term>Drug Combinations</term><term>Metronidazole</term><term>Miconazole</term><term>Pentamidine</term><term>Sulfamethoxazole</term><term>Trimethoprim</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Pneumocystis</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Pneumocystis</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Pneumocystis</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Amphotéricine B</term><term>Anti-infectieux</term><term>Association médicamenteuse</term><term>Chloroquine</term><term>Miconazole</term><term>Métronidazole</term><term>Pentamidine</term><term>Sulfaméthoxazole</term><term>Triméthoprime</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Abnormal liver function</term><term>Adverse reactions</term><term>Animals</term><term>Antimicrobial</term><term>Antimicrobial susceptibility</term><term>Carinii</term><term>Cell Line</term><term>Cell culture</term><term>Cell cultures</term><term>Chloroquine</term><term>Culture Media</term><term>Culture supernates</term><term>Culture system</term><term>Culture systems</term><term>Cyst</term><term>Data point</term><term>Good growth</term><term>Humans</term><term>Immunodeficiency syndrome</term><term>Isethionate</term><term>Metronidazole</term><term>Miconazole</term><term>Outgrowth</term><term>Outgrowth cultures</term><term>Pentamidine</term><term>Pentamidine isethionate</term><term>Pifer</term><term>Pneumocystis</term><term>Pneumocystis carinii</term><term>Pneumocystis carinii pneumonia</term><term>Pneumocystis pneumonia</term><term>Preliminary studies</term><term>Primary culture</term><term>Rats</term><term>Rats, Inbred Strains</term><term>Sulfamethoxazole</term><term>Supernate</term><term>Supernate organisms</term><term>Thymidine</term><term>Thymidine phosphorylase</term><term>Time Factors</term><term>Trimethoprim sulfamethoxazole</term><term>Trimethoprim, Sulfamethoxazole Drug Combination</term><term>Trophozoite</term><term>Unpublished data</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Association triméthoprime-sulfaméthoxazole</term><term>Facteurs temps</term><term>Humains</term><term>Lignée cellulaire</term><term>Lignées consanguines de rats</term><term>Milieux de culture</term><term>Pneumocystis</term><term>Rats</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Pneumocystiscarinii from infected rats were cultured on infected WI-38 human lung fibroblasts. After cultures were established, medium was replaced by medium containing antimicrobials and supernate organisms counted at specified times. Results show that metronidazole had no effect, amphotericin B suppressed organisms at 5 but not 0.5 μg/ml, and miconazole, chloroquine, trimethoprim-sulfamethoxazole, and pentamidine isethionate suppressed organisms at the concentrations tested.</div></front></TEI><double doi="10.1016/0732-8893(85)90076-8"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Antimicrobial susceptibility of Pneumocystis carinii in culture</title><author><name sortKey="Bartlett, Marilyn S" sort="Bartlett, Marilyn S" uniqKey="Bartlett M" first="Marilyn S." last="Bartlett">Marilyn S. Bartlett</name></author><author><name sortKey="Eichholtz, Rosanne" sort="Eichholtz, Rosanne" uniqKey="Eichholtz R" first="Rosanne" last="Eichholtz">Rosanne Eichholtz</name></author><author><name sortKey="Smith, James W" sort="Smith, James W" uniqKey="Smith J" first="James W." last="Smith">James W. Smith</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:011A64114B48F7F893327F4257100FCF7B973E69</idno><date when="1985" year="1985">1985</date><idno type="doi">10.1016/0732-8893(85)90076-8</idno><idno type="url">https://api.istex.fr/ark:/67375/6H6-P306771M-N/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000F54</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000F54</idno><idno type="wicri:Area/Istex/Curation">000F54</idno><idno type="wicri:Area/Istex/Checkpoint">002257</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">002257</idno><idno type="wicri:doubleKey">0732-8893:1985:Bartlett M:antimicrobial:susceptibility:of</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Antimicrobial susceptibility of Pneumocystis carinii in culture</title><author><name sortKey="Bartlett, Marilyn S" sort="Bartlett, Marilyn S" uniqKey="Bartlett M" first="Marilyn S." last="Bartlett">Marilyn S. Bartlett</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>the Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Eichholtz, Rosanne" sort="Eichholtz, Rosanne" uniqKey="Eichholtz R" first="Rosanne" last="Eichholtz">Rosanne Eichholtz</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>the Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Smith, James W" sort="Smith, James W" uniqKey="Smith J" first="James W." last="Smith">James W. Smith</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>the Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Diagnostic Microbiology & Infectious Disease</title><title level="j" type="abbrev">DMB</title><idno type="ISSN">0732-8893</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1985">1985</date><biblScope unit="volume">3</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="381">381</biblScope><biblScope unit="page" to="387">387</biblScope></imprint><idno type="ISSN">0732-8893</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0732-8893</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Abnormal liver function</term><term>Adverse reactions</term><term>Antimicrobial</term><term>Antimicrobial susceptibility</term><term>Carinii</term><term>Cell culture</term><term>Cell cultures</term><term>Chloroquine</term><term>Culture supernates</term><term>Culture system</term><term>Culture systems</term><term>Cyst</term><term>Data point</term><term>Good growth</term><term>Immunodeficiency syndrome</term><term>Isethionate</term><term>Metronidazole</term><term>Miconazole</term><term>Outgrowth</term><term>Outgrowth cultures</term><term>Pentamidine</term><term>Pentamidine isethionate</term><term>Pifer</term><term>Pneumocystis</term><term>Pneumocystis carinii</term><term>Pneumocystis carinii pneumonia</term><term>Pneumocystis pneumonia</term><term>Preliminary studies</term><term>Primary culture</term><term>Sulfamethoxazole</term><term>Supernate</term><term>Supernate organisms</term><term>Thymidine</term><term>Thymidine phosphorylase</term><term>Trimethoprim sulfamethoxazole</term><term>Trophozoite</term><term>Unpublished data</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Pneumocystiscarinii from infected rats were cultured on infected WI-38 human lung fibroblasts. After cultures were established, medium was replaced by medium containing antimicrobials and supernate organisms counted at specified times. Results show that metronidazole had no effect, amphotericin B suppressed organisms at 5 but not 0.5 μg/ml, and miconazole, chloroquine, trimethoprim-sulfamethoxazole, and pentamidine isethionate suppressed organisms at the concentrations tested.</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antimicrobial susceptibility of Pneumocystis carinii in culture.</title><author><name sortKey="Bartlett, M S" sort="Bartlett, M S" uniqKey="Bartlett M" first="M S" last="Bartlett">M S Bartlett</name></author><author><name sortKey="Eichholtz, R" sort="Eichholtz, R" uniqKey="Eichholtz R" first="R" last="Eichholtz">R. Eichholtz</name></author><author><name sortKey="Smith, J W" sort="Smith, J W" uniqKey="Smith J" first="J W" last="Smith">J W Smith</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1985">1985</date><idno type="RBID">pubmed:3875445</idno><idno type="pmid">3875445</idno><idno type="doi">10.1016/0732-8893(85)90076-8</idno><idno type="wicri:Area/PubMed/Corpus">000590</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000590</idno><idno type="wicri:Area/PubMed/Curation">000590</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000590</idno><idno type="wicri:Area/PubMed/Checkpoint">000565</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000565</idno><idno type="wicri:Area/Ncbi/Merge">001062</idno><idno type="wicri:Area/Ncbi/Curation">001062</idno><idno type="wicri:Area/Ncbi/Checkpoint">001062</idno><idno type="wicri:doubleKey">0732-8893:1985:Bartlett M:antimicrobial:susceptibility:of</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Antimicrobial susceptibility of Pneumocystis carinii in culture.</title><author><name sortKey="Bartlett, M S" sort="Bartlett, M S" uniqKey="Bartlett M" first="M S" last="Bartlett">M S Bartlett</name></author><author><name sortKey="Eichholtz, R" sort="Eichholtz, R" uniqKey="Eichholtz R" first="R" last="Eichholtz">R. Eichholtz</name></author><author><name sortKey="Smith, J W" sort="Smith, J W" uniqKey="Smith J" first="J W" last="Smith">J W Smith</name></author></analytic><series><title level="j">Diagnostic microbiology and infectious disease</title><idno type="ISSN">0732-8893</idno><imprint><date when="1985" type="published">1985</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amphotericin B (pharmacology)</term><term>Animals</term><term>Anti-Infective Agents (pharmacology)</term><term>Cell Line</term><term>Chloroquine (pharmacology)</term><term>Culture Media</term><term>Drug Combinations (pharmacology)</term><term>Humans</term><term>Metronidazole (pharmacology)</term><term>Miconazole (pharmacology)</term><term>Pentamidine (pharmacology)</term><term>Pneumocystis (drug effects)</term><term>Pneumocystis (growth & development)</term><term>Rats</term><term>Rats, Inbred Strains</term><term>Sulfamethoxazole (pharmacology)</term><term>Time Factors</term><term>Trimethoprim (pharmacology)</term><term>Trimethoprim, Sulfamethoxazole Drug Combination</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Amphotéricine B (pharmacologie)</term><term>Animaux</term><term>Anti-infectieux (pharmacologie)</term><term>Association médicamenteuse (pharmacologie)</term><term>Association triméthoprime-sulfaméthoxazole</term><term>Chloroquine (pharmacologie)</term><term>Facteurs temps</term><term>Humains</term><term>Lignée cellulaire</term><term>Lignées consanguines de rats</term><term>Miconazole (pharmacologie)</term><term>Milieux de culture</term><term>Métronidazole (pharmacologie)</term><term>Pentamidine (pharmacologie)</term><term>Pneumocystis ()</term><term>Pneumocystis (croissance et développement)</term><term>Rats</term><term>Sulfaméthoxazole (pharmacologie)</term><term>Triméthoprime (pharmacologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Amphotericin B</term><term>Anti-Infective Agents</term><term>Chloroquine</term><term>Drug Combinations</term><term>Metronidazole</term><term>Miconazole</term><term>Pentamidine</term><term>Sulfamethoxazole</term><term>Trimethoprim</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Pneumocystis</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Pneumocystis</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Pneumocystis</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Amphotéricine B</term><term>Anti-infectieux</term><term>Association médicamenteuse</term><term>Chloroquine</term><term>Miconazole</term><term>Métronidazole</term><term>Pentamidine</term><term>Sulfaméthoxazole</term><term>Triméthoprime</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Line</term><term>Culture Media</term><term>Humans</term><term>Rats</term><term>Rats, Inbred Strains</term><term>Time Factors</term><term>Trimethoprim, Sulfamethoxazole Drug Combination</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Association triméthoprime-sulfaméthoxazole</term><term>Facteurs temps</term><term>Humains</term><term>Lignée cellulaire</term><term>Lignées consanguines de rats</term><term>Milieux de culture</term><term>Pneumocystis</term><term>Rats</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Pneumocystis carinii from infected rats were cultured on infected WI-38 human lung fibroblasts. After cultures were established, medium was replaced by medium containing antimicrobials and supernate organisms counted at specified times. Results show that metronidazole had no effect, amphotericin B suppressed organisms at 5 but not 0.5 microgram/ml, and miconazole, chloroquine, trimethoprim-sulfamethoxazole, and pentamidine isethionate suppressed organisms at the concentrations tested.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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