Massive eosinophilia in rheumatoid arthritis: Report of four cases
Identifieur interne : 003498 ( Main/Merge ); précédent : 003497; suivant : 003499Massive eosinophilia in rheumatoid arthritis: Report of four cases
Auteurs : P. T. Dawes [Royaume-Uni] ; D. H. Smith [Royaume-Uni] ; D. L. Scott [Royaume-Uni]Source :
- Clinical Rheumatology [ 0770-3198 ] ; 1986-03-01.
English descriptors
- KwdEn :
- Teeft :
- Adverse reaction, Adverse reactions, Arthritis, Arthritis rheum, Cell count, Disease process, Drug therapy, Eosinophil, Eosinophil count, Eosinophilia, Gold therapy, Hypereosinophilic, Hypereosinophilic syndrome, Massive eosinophilia, Months therapy, Nailfold, Nailfold vasculitis, Nodule, Penicillamine, Rheum, Rheumatoid, Rheumatoid arthritis, Rheumatoid lung disease, Second line drugs, Staffordshire rheumatology centre, Subcutaneous nodules, Synovitis, Vasculitis.
Abstract
Summary: We report four cases of massive eosinophilia (>1.5×109'/l) a phenomenon uncommon in rheumatoid arthritis. In two patients it preceded therapy with second line anti-rheumatic drugs. The others developed it during therapy with penicillamine and gold, though neither had an adverse reaction. It appears there are two patterns of massive eosinophilia in RA; one is related to the disease process the other to drug therapy. It does not necessarily predict adverse drug reactions nor preclude treatment with anti-rheumatic therapy.
Url:
DOI: 10.1007/BF02030969
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