[Dermatomyositis: clinical study of 34 patients].
Identifieur interne : 002453 ( Main/Merge ); précédent : 002452; suivant : 002454[Dermatomyositis: clinical study of 34 patients].
Auteurs : M. Marschalk [Hongrie] ; G. P Nyai ; E. Ablonczy ; A. HorváthSource :
- Orvosi hetilap [ 0030-6002 ] ; 2000.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Dermatomyosite.
- traitement médicamenteux : Dermatomyosite.
- usage thérapeutique : Immunosuppresseurs.
- Adulte, Adulte d'âge moyen, Dermatomyosite, Diagnostic différentiel, Femelle, Humains, Mâle, Sujet âgé, Études rétrospectives.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Immunosuppressive Agents.
- complications : Dermatomyositis.
- diagnosis : Dermatomyositis.
- drug therapy : Dermatomyositis.
- Adult, Aged, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Retrospective Studies.
Abstract
Clinical data of 34 patients with DM, who have been treated during the years 1971 and 1998 were evaluated. 79% of the patients (27 patients) were female, 21% of them (7 patients) were male. 59% of the patients (20 pts) were between the ages of 41 and 50 years. The characteristic heliotrop rash were observed in 26 patients, Gottron's papules in 20 patients, poikiloderma in 2 patients, calcification, ulcers, Raynaud syndrome in 1 patient. 3 of the 34 patients presented with strongly itching erythematopapulosus symptoms, most prominently on the scalp. Cardiac involvement were present in 10 patients (29%), lung involvement in 8 patients (23%), gastrointestinal complaints in 11 patients, dysphagia, dysphonia in 4 patients, joint pain in 5 patients. Overlap syndrome--scleroderma-dermatomyositis, SLE-dermatomyositis--was present in 2 patients. 9 of the 34 patients (26%) suffered from malignant tumours: gastric, breast, lung, epipharynx carcinoma, malignant melanoma. 13 of the 34 patients have been treated with corticosteroids together with immunosuppressor agents, in most cases azathioprin was administered. Cyclosporin was given in 7 cases, chloroquine in 2 cases.
PubMed: 10697980
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pubmed:10697980Le document en format XML
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<term>Aged</term>
<term>Dermatomyositis (complications)</term>
<term>Dermatomyositis (diagnosis)</term>
<term>Dermatomyositis (drug therapy)</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Humans</term>
<term>Immunosuppressive Agents (therapeutic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Dermatomyosite ()</term>
<term>Dermatomyosite (diagnostic)</term>
<term>Dermatomyosite (traitement médicamenteux)</term>
<term>Diagnostic différentiel</term>
<term>Femelle</term>
<term>Humains</term>
<term>Immunosuppresseurs (usage thérapeutique)</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Études rétrospectives</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Immunosuppressive Agents</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Dermatomyositis</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dermatomyositis</term>
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<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Dermatomyosite</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dermatomyositis</term>
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<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Dermatomyosite</term>
<term>Diagnostic différentiel</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Études rétrospectives</term>
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<front><div type="abstract" xml:lang="en">Clinical data of 34 patients with DM, who have been treated during the years 1971 and 1998 were evaluated. 79% of the patients (27 patients) were female, 21% of them (7 patients) were male. 59% of the patients (20 pts) were between the ages of 41 and 50 years. The characteristic heliotrop rash were observed in 26 patients, Gottron's papules in 20 patients, poikiloderma in 2 patients, calcification, ulcers, Raynaud syndrome in 1 patient. 3 of the 34 patients presented with strongly itching erythematopapulosus symptoms, most prominently on the scalp. Cardiac involvement were present in 10 patients (29%), lung involvement in 8 patients (23%), gastrointestinal complaints in 11 patients, dysphagia, dysphonia in 4 patients, joint pain in 5 patients. Overlap syndrome--scleroderma-dermatomyositis, SLE-dermatomyositis--was present in 2 patients. 9 of the 34 patients (26%) suffered from malignant tumours: gastric, breast, lung, epipharynx carcinoma, malignant melanoma. 13 of the 34 patients have been treated with corticosteroids together with immunosuppressor agents, in most cases azathioprin was administered. Cyclosporin was given in 7 cases, chloroquine in 2 cases.</div>
</front>
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