Pancreatitis leading to thrombotic thrombocytopenic purpura in systemic lupus erythematosus: a case report and review of literature
Identifieur interne : 002098 ( Main/Merge ); précédent : 002097; suivant : 002099Pancreatitis leading to thrombotic thrombocytopenic purpura in systemic lupus erythematosus: a case report and review of literature
Auteurs : R. Singh [États-Unis] ; B. Saunders [États-Unis] ; E. Scopelitis [États-Unis]Source :
- Lupus [ 0961-2033 ] ; 2003-02.
English descriptors
- Teeft :
- Abdominal pain, Acute pancreatitis, Antiphospholipid, Antiphospholipid antibodies, Antiphospholipid syndrome, Arthritis rheum, Bilirubin, Blood cells, Case report, Case reports, Catastrophic antiphospholipid syndrome, Clinical features, Differential diagnosis, Erythematosus, Etiology, Health sciences center, Lupus, Mental status, Neurological, Pancreatitis, Peripheral blood smear, Plasmapheresis, Platelet, Platelet count, Proteinuria, Pulse dose, Purpura, Rare syndrome, Renal, Renal insuf ciency, Syndrome, Systemic lupus erythematosus, Thrombocytopenia, Thrombocytopenic, Thrombotic, Thrombotic microangiopathy, Thrombotic thrombocytopenic purpura, Total bilirubin, Unusual complication.
Abstract
Pancreatitis is a well-establishedbut unusual complicationof thrombotic thrombocytopenicpurpura (TTP). It is also an unusual complication of systemic lupus erythematosus (SLE). However, TTP occurring as a consequence of acute pancreatitis in a patient with SLE has never been reported. We report a 24-year-old African American woman with active systemic lupus (SLE) who developed thrombotic thrombocytopenic purpura (TTP) following an episode of acute pancreatitis. The TTP was manifested by low-grade fever, microangiopathic hemolytic anemia, renal insufficiency, altered mental status, seizures and thrombocytopenia. The patient was initially treated with pulse corticosteroids with inadequate response and subsequentlywith daily plasmaphresis, leading to full remission. This case represents first report of pancreatitis leading to TTP in a patient with systemic lupus erythematosus.
Url:
DOI: 10.1191/0961203303lu258cr
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Singh</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea><placeName><region type="state">Louisiane</region></placeName></affiliation></author><author wicri:is="90%"><name sortKey="Saunders, B" sort="Saunders, B" uniqKey="Saunders B" first="B" last="Saunders">B. Saunders</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, LSU Health Sciences Center, New Orleans, Louisiana</wicri:regionArea><placeName><region type="state">Louisiane</region></placeName></affiliation></author><author wicri:is="90%"><name sortKey="Scopelitis, E" sort="Scopelitis, E" uniqKey="Scopelitis E" first="E" last="Scopelitis">E. 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It is also an unusual complication of systemic lupus erythematosus (SLE). However, TTP occurring as a consequence of acute pancreatitis in a patient with SLE has never been reported. We report a 24-year-old African American woman with active systemic lupus (SLE) who developed thrombotic thrombocytopenic purpura (TTP) following an episode of acute pancreatitis. The TTP was manifested by low-grade fever, microangiopathic hemolytic anemia, renal insufficiency, altered mental status, seizures and thrombocytopenia. The patient was initially treated with pulse corticosteroids with inadequate response and subsequentlywith daily plasmaphresis, leading to full remission. This case represents first report of pancreatitis leading to TTP in a patient with systemic lupus erythematosus.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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