Long-Term Lung Function and Exercise Capacity in Postinfectious chILD
Identifieur interne : 000679 ( Main/Merge ); précédent : 000678; suivant : 000680Long-Term Lung Function and Exercise Capacity in Postinfectious chILD
Auteurs : Yagmur Sisman ; Frederik F. Buchvald ; Astrid Madsen Ring ; Katharina Wassilew ; Kim Gjerum NielsenSource :
- Pediatric Allergy, Immunology, and Pulmonology [ 2151-321X ] ; 2019.
Abstract
Url:
DOI: 10.1089/ped.2018.0973
PubMed: 31032143
PubMed Central: 6484343
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PMC:6484343Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Long-Term Lung Function and Exercise Capacity in Postinfectious chILD</title>
<author><name sortKey="Sisman, Yagmur" sort="Sisman, Yagmur" uniqKey="Sisman Y" first="Yagmur" last="Sisman">Yagmur Sisman</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Buchvald, Frederik F" sort="Buchvald, Frederik F" uniqKey="Buchvald F" first="Frederik F." last="Buchvald">Frederik F. Buchvald</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
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<author><name sortKey="Ring, Astrid Madsen" sort="Ring, Astrid Madsen" uniqKey="Ring A" first="Astrid Madsen" last="Ring">Astrid Madsen Ring</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wassilew, Katharina" sort="Wassilew, Katharina" uniqKey="Wassilew K" first="Katharina" last="Wassilew">Katharina Wassilew</name>
<affiliation><nlm:aff id="aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nielsen, Kim Gjerum" sort="Nielsen, Kim Gjerum" uniqKey="Nielsen K" first="Kim Gjerum" last="Nielsen">Kim Gjerum Nielsen</name>
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</affiliation>
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<idno type="pmid">31032143</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Long-Term Lung Function and Exercise Capacity in Postinfectious chILD</title>
<author><name sortKey="Sisman, Yagmur" sort="Sisman, Yagmur" uniqKey="Sisman Y" first="Yagmur" last="Sisman">Yagmur Sisman</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Buchvald, Frederik F" sort="Buchvald, Frederik F" uniqKey="Buchvald F" first="Frederik F." last="Buchvald">Frederik F. Buchvald</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Ring, Astrid Madsen" sort="Ring, Astrid Madsen" uniqKey="Ring A" first="Astrid Madsen" last="Ring">Astrid Madsen Ring</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wassilew, Katharina" sort="Wassilew, Katharina" uniqKey="Wassilew K" first="Katharina" last="Wassilew">Katharina Wassilew</name>
<affiliation><nlm:aff id="aff2"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nielsen, Kim Gjerum" sort="Nielsen, Kim Gjerum" uniqKey="Nielsen K" first="Kim Gjerum" last="Nielsen">Kim Gjerum Nielsen</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Pediatric Allergy, Immunology, and Pulmonology</title>
<idno type="ISSN">2151-321X</idno>
<idno type="eISSN">2151-3228</idno>
<imprint><date when="2019">2019</date>
</imprint>
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<front><div type="abstract" xml:lang="en"><p><bold><italic>Background:</italic>
</bold>
Severe postinfectious diffuse pulmonary disease may clinically mimic other entities of children's interstitial lung disease and is clinically challenging comprising various disease severities despite treatment. Long-term lung function trend and physical capacity in children with postinfectious diffuse pulmonary disease are rarely reported. We investigated trends in pulmonary function by long-term follow-up and assessed physical capacity in such patients.</p>
<p><bold><italic>Methods:</italic>
</bold>
We performed a descriptive, single-center follow-up study in children with biopsy-verified postinfectious diffuse pulmonary disease. Patients with completed primary treatment course were eligible for follow-up, including pulmonary function and exercise (VO<sub>2peak</sub>
) testing.</p>
<p><bold><italic>Results:</italic>
</bold>
Thirty patients with postinfectious diffuse pulmonary disease were identified and included. Median (range) age at diagnose was 27.5 (2–172) months after a mean lag time of 23 months. <italic>H. influenzae</italic>
and <italic>rhinovirus</italic>
were the most frequent pathogens. Fifteen patients were available for follow-up after mean (range) 7.6 (2–15) years of treatment completion. Lung clearance index (LCI<sub>2.5</sub>
), forced expiratory volume in 1 second (FEV<sub>1</sub>
), and bronchodilator responsiveness were abnormal in 80%, 53%, and 44%, respectively. Diffusion capacity for monoxide was abnormal in 7% and total lung capacity in 33%. Only 8% demonstrated low VO<sub>2peak</sub>
, while 40% reported difficulties during physical exertion. Longitudinal data on spirometry (<italic>n</italic>
= 14) remained unchanged from end of treatment throughout follow-up. A significant association was found between zLCI<sub>2.5</sub>
and zFEV<sub>1</sub>
(multiple linear regression; <italic>r</italic>
<sup>2</sup>
= 0.61; <italic>P</italic>
= 0.0003).</p>
<p><bold><italic>Conclusion:</italic>
</bold>
Postinfectious diffuse pulmonary disease in children carries a varying degree of chronic pulmonary impairment with onset of symptoms in the first months of life and a typical considerable lag time before diagnosis. Follow-up several years after the initial injury demonstrated moderate-to-severe peripheral airway impairment although no further lung function decline was found years after completion of treatment. Despite acceptable VO<sub>2peak</sub>
, a considerable proportion struggled during heavy exercise.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Fischer, Gb" uniqKey="Fischer G">GB Fischer</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Moonnumakal, Sp" uniqKey="Moonnumakal S">SP Moonnumakal</name>
</author>
</analytic>
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<biblStruct><analytic><author><name sortKey="Smith, Kj" uniqKey="Smith K">KJ Smith</name>
</author>
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<biblStruct><analytic><author><name sortKey="Kurland, G" uniqKey="Kurland G">G Kurland</name>
</author>
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<biblStruct><analytic><author><name sortKey="Zhang, L" uniqKey="Zhang L">L Zhang</name>
</author>
</analytic>
</biblStruct>
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</author>
</analytic>
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<biblStruct><analytic><author><name sortKey="Colom, Aj" uniqKey="Colom A">AJ Colom</name>
</author>
</analytic>
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<biblStruct><analytic><author><name sortKey="Castro Rodriguez, Ja" uniqKey="Castro Rodriguez J">JA Castro-Rodriguez</name>
</author>
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</author>
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</author>
</analytic>
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<biblStruct><analytic><author><name sortKey="Cazzato, S" uniqKey="Cazzato S">S Cazzato</name>
</author>
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<biblStruct><analytic><author><name sortKey="Robinson, Pd" uniqKey="Robinson P">PD Robinson</name>
</author>
</analytic>
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<biblStruct><analytic><author><name sortKey="Robinson, Pd" uniqKey="Robinson P">PD Robinson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Houltz, B" uniqKey="Houltz B">B Houltz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Miller, Mr" uniqKey="Miller M">MR Miller</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Macintyre, N" uniqKey="Macintyre N">N Macintyre</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stocks, J" uniqKey="Stocks J">J Stocks</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Pellegrino, R" uniqKey="Pellegrino R">R Pellegrino</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Madsen, A" uniqKey="Madsen A">A Madsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mattiello, R" uniqKey="Mattiello R">R Mattiello</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sisman, Y" uniqKey="Sisman Y">Y Sisman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Uhlving, Hh" uniqKey="Uhlving H">HH Uhlving</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kongstad, T" uniqKey="Kongstad T">T Kongstad</name>
</author>
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<biblStruct><analytic><author><name sortKey="Milani, Rv" uniqKey="Milani R">RV Milani</name>
</author>
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<biblStruct><analytic><author><name sortKey="Zhang, L" uniqKey="Zhang L">L Zhang</name>
</author>
</analytic>
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<biblStruct><analytic><author><name sortKey="Fischer, Gb" uniqKey="Fischer G">GB Fischer</name>
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<biblStruct><analytic><author><name sortKey="Ryu, Jh" uniqKey="Ryu J">JH Ryu</name>
</author>
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<biblStruct><analytic><author><name sortKey="Clement, A" uniqKey="Clement A">A Clement</name>
</author>
</analytic>
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</author>
</analytic>
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</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Green, K" uniqKey="Green K">K Green</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jensen, Ea" uniqKey="Jensen E">EA Jensen</name>
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