The Biological and Chemical Diversity of Tetramic Acid Compounds from Marine-Derived Microorganisms
Identifieur interne : 000031 ( Main/Merge ); précédent : 000030; suivant : 000032The Biological and Chemical Diversity of Tetramic Acid Compounds from Marine-Derived Microorganisms
Auteurs : Minghua Jiang [République populaire de Chine] ; Senhua Chen [République populaire de Chine] ; Jing Li [République populaire de Chine] ; Lan Liu [République populaire de Chine]Source :
- Marine Drugs [ 1660-3397 ] ; 2020.
Abstract
Tetramic acid (pyrrolidine-2,4-dione) compounds, isolated from a variety of marine and terrestrial organisms, have attracted considerable attention for their diverse, challenging structural complexity and promising bioactivities. In the past decade, marine-derived microorganisms have become great repositories of novel tetramic acids. Here, we discuss the biological activities of 277 tetramic acids of eight classifications (simple 3-acyl tetramic acids, 3-oligoenoyltetramic acids, 3-decalinoyltetramic acid, 3-spirotetramic acids, macrocyclic tetramic acids,
Url:
DOI: 10.3390/md18020114
PubMed: 32075282
PubMed Central: 7074263
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PMC:7074263Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Tetramic acid (pyrrolidine-2,4-dione) compounds, isolated from a variety of marine and terrestrial organisms, have attracted considerable attention for their diverse, challenging structural complexity and promising bioactivities. In the past decade, marine-derived microorganisms have become great repositories of novel tetramic acids. Here, we discuss the biological activities of 277 tetramic acids of eight classifications (simple 3-acyl tetramic acids, 3-oligoenoyltetramic acids, 3-decalinoyltetramic acid, 3-spirotetramic acids, macrocyclic tetramic acids, <italic>N</italic>
-acylated tetramic acids, α-cyclopiazonic acid-type tetramic acids, and other tetramic acids) from marine-derived microbes, including fungi, actinobacteria, bacteria, and cyanobacteria, as reported in 195 research studies up to 2019.</p>
</div>
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</TEI>
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