Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer
Identifieur interne : 000A86 ( Main/Exploration ); précédent : 000A85; suivant : 000A87Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer
Auteurs : Sofia Avnet [Italie] ; Nicola Baldini [Italie] ; Lucie Brisson [France] ; Stine Falsig Pedersen [Danemark] ; Paolo E. Porporato [Italie] ; Pierre Sonveaux [Belgique] ; Gyorgy Szabadkai [Italie, Royaume-Uni] ; Silvia Pastorekova [Slovaquie]Source :
- Frontiers in Oncology [ 2234-943X ] ; 2019.
Abstract
The metabolism of cancer cells differs from that of their normal counterparts in a spectrum of attributes, including imbalances in diverse metabolic arms and pathways, metabolic plasticity and extent of adaptive responses, levels, and activities of metabolic enzymes and their upstream regulators and abnormal fluxes of metabolic intermediates and products. These attributes endow cancer cells with the ability to survive stressors of the tumor microenvironment and enable them to landscape and exploit the host terrain, thereby facilitating cancer progression and therapy resistance. Understanding the molecular and physiological principles of cancer metabolism is one of the key prerequisites for the development of better anticancer treatments. Therefore, various aspects of cancer metabolism were addressed at the 5th annual meeting of the International Society of Cancer Metabolism (ISCaM) in Bratislava, Slovakia, on October 17–20, 2018. The meeting presentations and discussions were traditionally focused on mechanistic, translational, and clinical characteristics of metabolism and pH control in cancer, at the level of molecular pathways, cells, tissues, and organisms. In order to reflect major healthcare challenges of the current era, ISCaM has extended its scope to metabolic disorders contributing to cancer, as well as to opportunities for their prevention, intervention, and therapeutic targeting.
Url:
DOI: 10.3389/fonc.2019.01332
PubMed: 31850217
PubMed Central: 6892776
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000988
- to stream Pmc, to step Curation: 000988
- to stream Pmc, to step Checkpoint: 000A12
- to stream Ncbi, to step Merge: 000D38
- to stream Ncbi, to step Curation: 000D38
- to stream Ncbi, to step Checkpoint: 000D38
- to stream Main, to step Merge: 000A86
- to stream Main, to step Curation: 000A86
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer</title>
<author><name sortKey="Avnet, Sofia" sort="Avnet, Sofia" uniqKey="Avnet S" first="Sofia" last="Avnet">Sofia Avnet</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Orthopaedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli</institution>
,<addr-line>Bologna</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Baldini, Nicola" sort="Baldini, Nicola" uniqKey="Baldini N" first="Nicola" last="Baldini">Nicola Baldini</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Orthopaedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli</institution>
,<addr-line>Bologna</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Biomedical and Neuromotor Sciences, University of Bologna</institution>
,<addr-line>Bologna</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brisson, Lucie" sort="Brisson, Lucie" uniqKey="Brisson L" first="Lucie" last="Brisson">Lucie Brisson</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>INSERM UMR1069, Nutrition, Croissance et Cancer, University of Tours</institution>
,<addr-line>Tours</addr-line>
,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pedersen, Stine Falsig" sort="Pedersen, Stine Falsig" uniqKey="Pedersen S" first="Stine Falsig" last="Pedersen">Stine Falsig Pedersen</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Biology, Faculty of Science, University of Copenhagen</institution>
,<addr-line>Copenhagen</addr-line>
,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Porporato, Paolo E" sort="Porporato, Paolo E" uniqKey="Porporato P" first="Paolo E." last="Porporato">Paolo E. Porporato</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino</institution>
,<addr-line>Turin</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sonveaux, Pierre" sort="Sonveaux, Pierre" uniqKey="Sonveaux P" first="Pierre" last="Sonveaux">Pierre Sonveaux</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain</institution>
,<addr-line>Brussels</addr-line>
,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Szabadkai, Gyorgy" sort="Szabadkai, Gyorgy" uniqKey="Szabadkai G" first="Gyorgy" last="Szabadkai">Gyorgy Szabadkai</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Biomedical Sciences, University of Padua</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Department of Cell and Developmental Biology, Consortium for Mitochondrial Research, University College London</institution>
,<addr-line>London</addr-line>
,<country>United Kingdom</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>The Francis Crick Institute</institution>
,<addr-line>London</addr-line>
,<country>United Kingdom</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pastorekova, Silvia" sort="Pastorekova, Silvia" uniqKey="Pastorekova S" first="Silvia" last="Pastorekova">Silvia Pastorekova</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Biomedical Research Center, Slovak Academy of Sciences</institution>
,<addr-line>Bratislava</addr-line>
,<country>Slovakia</country>
</nlm:aff>
<country xml:lang="fr">Slovaquie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">31850217</idno>
<idno type="pmc">6892776</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892776</idno>
<idno type="RBID">PMC:6892776</idno>
<idno type="doi">10.3389/fonc.2019.01332</idno>
<date when="2019">2019</date>
<idno type="wicri:Area/Pmc/Corpus">000988</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000988</idno>
<idno type="wicri:Area/Pmc/Curation">000988</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000988</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000A12</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000A12</idno>
<idno type="wicri:Area/Ncbi/Merge">000D38</idno>
<idno type="wicri:Area/Ncbi/Curation">000D38</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000D38</idno>
<idno type="wicri:Area/Main/Merge">000A86</idno>
<idno type="wicri:Area/Main/Curation">000A86</idno>
<idno type="wicri:Area/Main/Exploration">000A86</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer</title>
<author><name sortKey="Avnet, Sofia" sort="Avnet, Sofia" uniqKey="Avnet S" first="Sofia" last="Avnet">Sofia Avnet</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Orthopaedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli</institution>
,<addr-line>Bologna</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Baldini, Nicola" sort="Baldini, Nicola" uniqKey="Baldini N" first="Nicola" last="Baldini">Nicola Baldini</name>
<affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Orthopaedic Pathophysiology and Regenerative Medicine Unit, IRCCS Istituto Ortopedico Rizzoli</institution>
,<addr-line>Bologna</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Department of Biomedical and Neuromotor Sciences, University of Bologna</institution>
,<addr-line>Bologna</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brisson, Lucie" sort="Brisson, Lucie" uniqKey="Brisson L" first="Lucie" last="Brisson">Lucie Brisson</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><institution>INSERM UMR1069, Nutrition, Croissance et Cancer, University of Tours</institution>
,<addr-line>Tours</addr-line>
,<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pedersen, Stine Falsig" sort="Pedersen, Stine Falsig" uniqKey="Pedersen S" first="Stine Falsig" last="Pedersen">Stine Falsig Pedersen</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Biology, Faculty of Science, University of Copenhagen</institution>
,<addr-line>Copenhagen</addr-line>
,<country>Denmark</country>
</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Porporato, Paolo E" sort="Porporato, Paolo E" uniqKey="Porporato P" first="Paolo E." last="Porporato">Paolo E. Porporato</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino</institution>
,<addr-line>Turin</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Sonveaux, Pierre" sort="Sonveaux, Pierre" uniqKey="Sonveaux P" first="Pierre" last="Sonveaux">Pierre Sonveaux</name>
<affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain</institution>
,<addr-line>Brussels</addr-line>
,<country>Belgium</country>
</nlm:aff>
<country xml:lang="fr">Belgique</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Szabadkai, Gyorgy" sort="Szabadkai, Gyorgy" uniqKey="Szabadkai G" first="Gyorgy" last="Szabadkai">Gyorgy Szabadkai</name>
<affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Biomedical Sciences, University of Padua</institution>
,<addr-line>Padua</addr-line>
,<country>Italy</country>
</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Department of Cell and Developmental Biology, Consortium for Mitochondrial Research, University College London</institution>
,<addr-line>London</addr-line>
,<country>United Kingdom</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff9"><institution>The Francis Crick Institute</institution>
,<addr-line>London</addr-line>
,<country>United Kingdom</country>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Pastorekova, Silvia" sort="Pastorekova, Silvia" uniqKey="Pastorekova S" first="Silvia" last="Pastorekova">Silvia Pastorekova</name>
<affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Biomedical Research Center, Slovak Academy of Sciences</institution>
,<addr-line>Bratislava</addr-line>
,<country>Slovakia</country>
</nlm:aff>
<country xml:lang="fr">Slovaquie</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series><title level="j">Frontiers in Oncology</title>
<idno type="eISSN">2234-943X</idno>
<imprint><date when="2019">2019</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>The metabolism of cancer cells differs from that of their normal counterparts in a spectrum of attributes, including imbalances in diverse metabolic arms and pathways, metabolic plasticity and extent of adaptive responses, levels, and activities of metabolic enzymes and their upstream regulators and abnormal fluxes of metabolic intermediates and products. These attributes endow cancer cells with the ability to survive stressors of the tumor microenvironment and enable them to landscape and exploit the host terrain, thereby facilitating cancer progression and therapy resistance. Understanding the molecular and physiological principles of cancer metabolism is one of the key prerequisites for the development of better anticancer treatments. Therefore, various aspects of cancer metabolism were addressed at the 5th annual meeting of the International Society of Cancer Metabolism (ISCaM) in Bratislava, Slovakia, on October 17–20, 2018. The meeting presentations and discussions were traditionally focused on mechanistic, translational, and clinical characteristics of metabolism and pH control in cancer, at the level of molecular pathways, cells, tissues, and organisms. In order to reflect major healthcare challenges of the current era, ISCaM has extended its scope to metabolic disorders contributing to cancer, as well as to opportunities for their prevention, intervention, and therapeutic targeting.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Spugnini, Ep" uniqKey="Spugnini E">EP Spugnini</name>
</author>
<author><name sortKey="Sonveaux, P" uniqKey="Sonveaux P">P Sonveaux</name>
</author>
<author><name sortKey="Stock, C" uniqKey="Stock C">C Stock</name>
</author>
<author><name sortKey="Perez Sayans, M" uniqKey="Perez Sayans M">M Perez-Sayans</name>
</author>
<author><name sortKey="De Milito, A" uniqKey="De Milito A">A De Milito</name>
</author>
<author><name sortKey="Avnet, S" uniqKey="Avnet S">S Avnet</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Baldini, N" uniqKey="Baldini N">N Baldini</name>
</author>
<author><name sortKey="Sonveaux, P" uniqKey="Sonveaux P">P Sonveaux</name>
</author>
<author><name sortKey="De Milito, A" uniqKey="De Milito A">A De Milito</name>
</author>
<author><name sortKey="Supuran, C" uniqKey="Supuran C">C Supuran</name>
</author>
<author><name sortKey="Otto, A" uniqKey="Otto A">A Otto</name>
</author>
<author><name sortKey="Stock, C" uniqKey="Stock C">C Stock</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Baldini, N" uniqKey="Baldini N">N Baldini</name>
</author>
<author><name sortKey="De Milito, A" uniqKey="De Milito A">A De Milito</name>
</author>
<author><name sortKey="Feron, O" uniqKey="Feron O">O Feron</name>
</author>
<author><name sortKey="Gillies, Rj" uniqKey="Gillies R">RJ Gillies</name>
</author>
<author><name sortKey="Michiels, C" uniqKey="Michiels C">C Michiels</name>
</author>
<author><name sortKey="Otto, Am" uniqKey="Otto A">AM Otto</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Avnet, S" uniqKey="Avnet S">S Avnet</name>
</author>
<author><name sortKey="Baldini, N" uniqKey="Baldini N">N Baldini</name>
</author>
<author><name sortKey="Brisson, L" uniqKey="Brisson L">L Brisson</name>
</author>
<author><name sortKey="De Milito, A" uniqKey="De Milito A">A De Milito</name>
</author>
<author><name sortKey="Otto, Am" uniqKey="Otto A">AM Otto</name>
</author>
<author><name sortKey="Pastorekova, S" uniqKey="Pastorekova S">S Pastorekova</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>Belgique</li>
<li>Danemark</li>
<li>France</li>
<li>Italie</li>
<li>Royaume-Uni</li>
<li>Slovaquie</li>
</country>
</list>
<tree><country name="Italie"><noRegion><name sortKey="Avnet, Sofia" sort="Avnet, Sofia" uniqKey="Avnet S" first="Sofia" last="Avnet">Sofia Avnet</name>
</noRegion>
<name sortKey="Baldini, Nicola" sort="Baldini, Nicola" uniqKey="Baldini N" first="Nicola" last="Baldini">Nicola Baldini</name>
<name sortKey="Baldini, Nicola" sort="Baldini, Nicola" uniqKey="Baldini N" first="Nicola" last="Baldini">Nicola Baldini</name>
<name sortKey="Porporato, Paolo E" sort="Porporato, Paolo E" uniqKey="Porporato P" first="Paolo E." last="Porporato">Paolo E. Porporato</name>
<name sortKey="Szabadkai, Gyorgy" sort="Szabadkai, Gyorgy" uniqKey="Szabadkai G" first="Gyorgy" last="Szabadkai">Gyorgy Szabadkai</name>
</country>
<country name="France"><noRegion><name sortKey="Brisson, Lucie" sort="Brisson, Lucie" uniqKey="Brisson L" first="Lucie" last="Brisson">Lucie Brisson</name>
</noRegion>
</country>
<country name="Danemark"><noRegion><name sortKey="Pedersen, Stine Falsig" sort="Pedersen, Stine Falsig" uniqKey="Pedersen S" first="Stine Falsig" last="Pedersen">Stine Falsig Pedersen</name>
</noRegion>
</country>
<country name="Belgique"><noRegion><name sortKey="Sonveaux, Pierre" sort="Sonveaux, Pierre" uniqKey="Sonveaux P" first="Pierre" last="Sonveaux">Pierre Sonveaux</name>
</noRegion>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Szabadkai, Gyorgy" sort="Szabadkai, Gyorgy" uniqKey="Szabadkai G" first="Gyorgy" last="Szabadkai">Gyorgy Szabadkai</name>
</noRegion>
<name sortKey="Szabadkai, Gyorgy" sort="Szabadkai, Gyorgy" uniqKey="Szabadkai G" first="Gyorgy" last="Szabadkai">Gyorgy Szabadkai</name>
</country>
<country name="Slovaquie"><noRegion><name sortKey="Pastorekova, Silvia" sort="Pastorekova, Silvia" uniqKey="Pastorekova S" first="Silvia" last="Pastorekova">Silvia Pastorekova</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A86 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000A86 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= ChloroquineV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:6892776 |texte= Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31850217" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a ChloroquineV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |