Anti-glutamic acid decarboxylase antibodies in a patient with systemic lupus erythematosus and fibromyalgia symptoms
Identifieur interne : 001F02 ( Main/Curation ); précédent : 001F01; suivant : 001F03Anti-glutamic acid decarboxylase antibodies in a patient with systemic lupus erythematosus and fibromyalgia symptoms
Auteurs : R M Taylor-Gjevre [Canada] ; J A Gjevre [Canada]Source :
- Lupus [ 0961-2033 ] ; 2005-06.
English descriptors
- Teeft :
- Autoimmune, Autoimmune contribution, Bromyalgia, Bromyalgia symptoms, Case report, Decarboxylase, Diabetes mellitus, Erythematosus, Further evaluation, Gaba, Gabaergic inhibition, Lupus, Muscle discomfort, Myalgia, Myalgia symptoms, Neuropathic pain, Pathogenic role, Royal university hospital, Spinal cord, Syndrome, Systemic lupus erythematosus, Tactile allodynia.
Abstract
We report the case of a 29-year old female nurse with a five-year history of systemic lupus erythematosus (SLE) involving multiple systems and on chronic prednisone therapy. This patient has a coexisting diagnosis of fibromyalgia fulfilling ACR criteria. A recent deterioration in her level of functioning in addition to a flare of her inflammatory disease led to further evaluation. During the course of investigation an anti-glutamic acid decarboxylase antibody was found to be present and significantly elevated. A therapeutic trial of baclofen did result in improvement of her subjective myalgias. We raise the possibility of an autoimmune contribution to myalgic symptoms in a portion of SLE patients.
Url:
DOI: 10.1191/0961203305lu2095cr
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