Multicentre survey of rheumatoid arthritis patients from Ministry of Health Rheumatology Centers in Malaysia
Identifieur interne : 001982 ( Main/Curation ); précédent : 001981; suivant : 001983Multicentre survey of rheumatoid arthritis patients from Ministry of Health Rheumatology Centers in Malaysia
Auteurs : Mohd Shahrir ; Mohd Shahdan ; Mohamed Shahid ; W. Sulaiman ; A. M. Mokhtar ; M. Othman ; A. Rosman ; S. G. Ong ; I. S. Lau ; M. M. Zain ; H. Yusof ; A. Ismail ; A. Yusof ; B. E. Tan ; H. C. Chong ; H. Hussein ; M. Eishwary ; N. A. Shahril ; M. I. Liza ; S. C. Gun ; Y. L. Loh ; B. De'Souza ; A. YusofSource :
- International Journal of Rheumatic Diseases [ 1756-1841 ] ; 2008-09.
English descriptors
- Teeft :
- Antirheumatic drugs, Arthritis, Clinical data, Collaborative study, Corrective surgery, Descriptive study, Disease prevalence, Ethnic group, Female patients, Government hospitals, Higher rates, Hydroxychloroquine, International journal, Malaysia, Male patients, Medical department pusat perubatan, Methotrexate, Multicentre survey, Peak onset, Rheumatic, Rheumatic diseases, Rheumatoid, Rheumatoid arthritis, Seremban hospitals, Sulfasalazine, Traditional remedies, Universiti kebangsaan malaysia.
Abstract
Aim: This is a rheumatoid arthritis (RA) descriptive study, the first of its kind carried out in Malaysia. Methods: This descriptive study involved 1084 RA patients’ epidemiological and clinical data taken from Selayang, Putrajaya, Taiping and Seremban hospitals from June 2004 to December 2005. Results: One thousand and eighty‐four RA patients'data were analysed; 960 (88.6%) patients were female and 124 (11.4%) were male, approximately 8 : 1 M : F ratio. The majority of the patients were Indian (591; 54.5%), followed by the Malays (340; 31.4%), Chinese (126; 11.6%), indigenous (13; 1.2%) and others (14; 1.3%). Mean age was 49.6 ± 11.8 years with the youngest being 15 years and the oldest 88 years of age. Mean age for males was 52.0 ± 12.0 and females 49.3 ± 11.7 years (P = 0.017). Most of these patients were housewives (565; 52.1%), followed by paid workers (266; 24.5%), retired patients (80; 7.4%), unemployed (76; 7.0%) and others (97; 8.9%). Mean duration of illness was 8.4 ± 6.7 years; 805 (74.3%) patients were relatively new patients (≤ 2 years illness duration) and 279 (25.7%) patients had illness duration > 2 years. Eight hundred and six (74.4%) were seropositive RA patients and 385 (35.5%) had presence of deformity. The majority of patients were treated with methotrexate (178; 16.4%), followed by combination of methotrexate, sulfasalazine and hydroxychloroquine (143; 13.2%), leflunomide (140; 12.9%), sulfasalazine (133; 12.3%) and combination of methotrexate and sulfasalazine (108; 10%). Conclusion: In the above study, the majority of patients were female (960; 88.6%), Indian (591; 54.5%), had a mean age of 49.6 ± 11.8 years, most were housewives with a mean duration of illness of 8.4 ± 6.7 years and were treated with methotrexate (178; 16.4%). The results of the study may help Malaysian rheumaologists to understand their patients better and treat RA holistically.
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DOI: 10.1111/j.1756-185X.2008.00379.x
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Mohd Shahrir<affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><wicri:noCountry code="subField">Serdang</wicri:noCountry></affiliation>Le document en format XML
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Othman</name></author><author><name sortKey="Rosman, A" sort="Rosman, A" uniqKey="Rosman A" first="A." last="Rosman">A. Rosman</name></author><author><name sortKey="Ong, S G" sort="Ong, S G" uniqKey="Ong S" first="S. G." last="Ong">S. G. Ong</name></author><author><name sortKey="Lau, I S" sort="Lau, I S" uniqKey="Lau I" first="I. S." last="Lau">I. S. Lau</name></author><author><name sortKey="Zain, M M" sort="Zain, M M" uniqKey="Zain M" first="M. M." last="Zain">M. M. Zain</name></author><author><name sortKey="Yusof, H" sort="Yusof, H" uniqKey="Yusof H" first="H." last="Yusof">H. Yusof</name></author><author><name sortKey="Ismail, A" sort="Ismail, A" uniqKey="Ismail A" first="A." last="Ismail">A. Ismail</name></author><author><name sortKey="Yusof, A" sort="Yusof, A" uniqKey="Yusof A" first="A." last="Yusof">A. Yusof</name></author><author><name sortKey="Tan, B E" sort="Tan, B E" uniqKey="Tan B" first="B. E." last="Tan">B. E. 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Yusof</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:57DB2F712F5DE54A5413E56C76980E8BCE708192</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1111/j.1756-185X.2008.00379.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-BGT9C4W4-7/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000445</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000445</idno><idno type="wicri:Area/Istex/Curation">000445</idno><idno type="wicri:Area/Istex/Checkpoint">000887</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000887</idno><idno type="wicri:doubleKey">1756-1841:2008:Shahrir M:multicentre:survey:of</idno><idno type="wicri:Area/Main/Merge">001990</idno><idno type="wicri:Area/Main/Curation">001982</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Multicentre survey of rheumatoid arthritis patients from Ministry of Health Rheumatology Centers in Malaysia</title><author><name sortKey="Shahrir, Mohd" sort="Shahrir, Mohd" uniqKey="Shahrir M" first="Mohd" last="Shahrir">Mohd Shahrir</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Shahdan, Mohd" sort="Shahdan, Mohd" uniqKey="Shahdan M" first="Mohd" last="Shahdan">Mohd Shahdan</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Shahid, Mohamed" sort="Shahid, Mohamed" uniqKey="Shahid M" first="Mohamed" last="Shahid">Mohamed Shahid</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Sulaiman, W" sort="Sulaiman, W" uniqKey="Sulaiman W" first="W." last="Sulaiman">W. Sulaiman</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Mokhtar, A M" sort="Mokhtar, A M" uniqKey="Mokhtar A" first="A. M." last="Mokhtar">A. M. Mokhtar</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Othman, M" sort="Othman, M" uniqKey="Othman M" first="M." last="Othman">M. Othman</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Rosman, A" sort="Rosman, A" uniqKey="Rosman A" first="A." last="Rosman">A. Rosman</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Ong, S G" sort="Ong, S G" uniqKey="Ong S" first="S. G." last="Ong">S. G. Ong</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Lau, I S" sort="Lau, I S" uniqKey="Lau I" first="I. S." last="Lau">I. S. Lau</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Zain, M M" sort="Zain, M M" uniqKey="Zain M" first="M. M." last="Zain">M. M. Zain</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Yusof, H" sort="Yusof, H" uniqKey="Yusof H" first="H." last="Yusof">H. Yusof</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Ismail, A" sort="Ismail, A" uniqKey="Ismail A" first="A." last="Ismail">A. Ismail</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Yusof, A" sort="Yusof, A" uniqKey="Yusof A" first="A." last="Yusof">A. Yusof</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Tan, B E" sort="Tan, B E" uniqKey="Tan B" first="B. E." last="Tan">B. E. Tan</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Chong, H C" sort="Chong, H C" uniqKey="Chong H" first="H. C." last="Chong">H. C. Chong</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Hussein, H" sort="Hussein, H" uniqKey="Hussein H" first="H." last="Hussein">H. Hussein</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Eishwary, M" sort="Eishwary, M" uniqKey="Eishwary M" first="M." last="Eishwary">M. Eishwary</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Shahril, N A" sort="Shahril, N A" uniqKey="Shahril N" first="N. A." last="Shahril">N. A. Shahril</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Liza, M I" sort="Liza, M I" uniqKey="Liza M" first="M. I." last="Liza">M. I. Liza</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Gun, S C" sort="Gun, S C" uniqKey="Gun S" first="S. C." last="Gun">S. C. Gun</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Loh, Y L" sort="Loh, Y L" uniqKey="Loh Y" first="Y. L." last="Loh">Y. L. Loh</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="De Souza, B" sort="De Souza, B" uniqKey="De Souza B" first="B." last="De'Souza">B. De'Souza</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Yusof, A" sort="Yusof, A" uniqKey="Yusof A" first="A." last="Yusof">A. Yusof</name><affiliation><wicri:noCountry code="subField">Serdang</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">International Journal of Rheumatic Diseases</title><title level="j" type="alt">INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES</title><idno type="ISSN">1756-1841</idno><idno type="eISSN">1756-185X</idno><imprint><biblScope unit="vol">11</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="287">287</biblScope><biblScope unit="page" to="292">292</biblScope><biblScope unit="page-count">6</biblScope><publisher>Blackwell Publishing Asia</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2008-09">2008-09</date></imprint><idno type="ISSN">1756-1841</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1756-1841</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Antirheumatic drugs</term><term>Arthritis</term><term>Clinical data</term><term>Collaborative study</term><term>Corrective surgery</term><term>Descriptive study</term><term>Disease prevalence</term><term>Ethnic group</term><term>Female patients</term><term>Government hospitals</term><term>Higher rates</term><term>Hydroxychloroquine</term><term>International journal</term><term>Malaysia</term><term>Male patients</term><term>Medical department pusat perubatan</term><term>Methotrexate</term><term>Multicentre survey</term><term>Peak onset</term><term>Rheumatic</term><term>Rheumatic diseases</term><term>Rheumatoid</term><term>Rheumatoid arthritis</term><term>Seremban hospitals</term><term>Sulfasalazine</term><term>Traditional remedies</term><term>Universiti kebangsaan malaysia</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Aim: This is a rheumatoid arthritis (RA) descriptive study, the first of its kind carried out in Malaysia. Methods: This descriptive study involved 1084 RA patients’ epidemiological and clinical data taken from Selayang, Putrajaya, Taiping and Seremban hospitals from June 2004 to December 2005. Results: One thousand and eighty‐four RA patients'data were analysed; 960 (88.6%) patients were female and 124 (11.4%) were male, approximately 8 : 1 M : F ratio. The majority of the patients were Indian (591; 54.5%), followed by the Malays (340; 31.4%), Chinese (126; 11.6%), indigenous (13; 1.2%) and others (14; 1.3%). Mean age was 49.6 ± 11.8 years with the youngest being 15 years and the oldest 88 years of age. Mean age for males was 52.0 ± 12.0 and females 49.3 ± 11.7 years (P = 0.017). Most of these patients were housewives (565; 52.1%), followed by paid workers (266; 24.5%), retired patients (80; 7.4%), unemployed (76; 7.0%) and others (97; 8.9%). Mean duration of illness was 8.4 ± 6.7 years; 805 (74.3%) patients were relatively new patients (≤ 2 years illness duration) and 279 (25.7%) patients had illness duration > 2 years. Eight hundred and six (74.4%) were seropositive RA patients and 385 (35.5%) had presence of deformity. The majority of patients were treated with methotrexate (178; 16.4%), followed by combination of methotrexate, sulfasalazine and hydroxychloroquine (143; 13.2%), leflunomide (140; 12.9%), sulfasalazine (133; 12.3%) and combination of methotrexate and sulfasalazine (108; 10%). Conclusion: In the above study, the majority of patients were female (960; 88.6%), Indian (591; 54.5%), had a mean age of 49.6 ± 11.8 years, most were housewives with a mean duration of illness of 8.4 ± 6.7 years and were treated with methotrexate (178; 16.4%). The results of the study may help Malaysian rheumaologists to understand their patients better and treat RA holistically.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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