Listeria monocytogenes meningitis in a young woman with systemic lupus erythematosus
Identifieur interne : 001702 ( Main/Curation ); précédent : 001701; suivant : 001703Listeria monocytogenes meningitis in a young woman with systemic lupus erythematosus
Auteurs : Ming-Chia Lee [Taïwan] ; Yao-Kuang Wu [Taïwan] ; Chun-Hsiung Chen [Taïwan] ; Ta-Wei Wu [Taïwan] ; Chih-Hsin Lee [Taïwan]Source :
- Rheumatology International [ 0172-8172 ] ; 2011-04-01.
English descriptors
Abstract
Abstract: Listeria meningitis, a rare but life-threatening infection in patients with systemic lupus erythematosus, often represents a diagnostic and therapeutic challenge because of its rarity and non-representative manifestations. L. monocytogenes is an intracellular pathogen capable of spreading directly from cell to cell without exposure to the extracellular humoral immune system. With the evolving trend of intense immunosuppressive therapy, patients with SLE usually have abnormal cell-mediated immunity and are susceptible to L. monocytogenes infections. The gastrointestinal tract is usually the portal of entry, and a transient gastroenteritis may precede the full-blown meningitides. Ampicillin and penicillin G are the drugs of choice. For patients who are allergic to penicillin, trimethoprim-sulfamethoxazole is an eligible alternative. Delay in diagnosis and inappropriate antibiotics are detrimental to the outcome. Herein, we report a young woman with systemic lupus erythematosus who developed listeria meningitis. Clinicians are advised to be aware of the clinical presentations of this disease.
Url:
DOI: 10.1007/s00296-010-1590-3
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type="eISSN">1437-160X</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="2011-04-01">2011-04-01</date><biblScope unit="volume">31</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="555">555</biblScope><biblScope unit="page" to="557">557</biblScope></imprint><idno type="ISSN">0172-8172</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0172-8172</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Connective tissue disease</term><term>Convulsion</term><term>Meningitis</term><term>Opportunistic infection</term><term>Septic shock</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Listeria meningitis, a rare but life-threatening infection in patients with systemic lupus erythematosus, often represents a diagnostic and therapeutic challenge because of its rarity and non-representative manifestations. L. monocytogenes is an intracellular pathogen capable of spreading directly from cell to cell without exposure to the extracellular humoral immune system. With the evolving trend of intense immunosuppressive therapy, patients with SLE usually have abnormal cell-mediated immunity and are susceptible to L. monocytogenes infections. The gastrointestinal tract is usually the portal of entry, and a transient gastroenteritis may precede the full-blown meningitides. Ampicillin and penicillin G are the drugs of choice. For patients who are allergic to penicillin, trimethoprim-sulfamethoxazole is an eligible alternative. Delay in diagnosis and inappropriate antibiotics are detrimental to the outcome. Herein, we report a young woman with systemic lupus erythematosus who developed listeria meningitis. Clinicians are advised to be aware of the clinical presentations of this disease.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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