ChloroquineV1, Main, Curation, bibRecord, 000351

The cat is out of the bag: How parasites know their hosts

Identifieur interne : 000351 ( Main/Curation ); précédent : 000350; suivant : 000352

The cat is out of the bag: How parasites know their hosts

Auteurs : Elizabeth D. English ; Boris Striepen

Source :

PLoS Biology [ 1544-9173 ] ; 2019.

RBID : PMC:6748446

Abstract

Toxoplasma gondii is a remarkably successful protozoan parasite that infects a third of the human population, along with most mammals and birds. However, the sexual portion of the parasite’s life cycle is narrowly limited to cats. How parasites distinguish between hosts has long been a mystery. A new study reveals that Toxoplasma identifies cats based on a single fatty acid, linoleic acid. Experimental manipulation of fatty acid metabolism by drug treatment turns a mouse into a cat in the “eye” of the parasite. This new model enables genetic crosses of an important human pathogen without the use of companion animals and opens the door to future discovery.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748446

DOI: 10.1371/journal.pbio.3000446
PubMed: 31487278
PubMed Central: 6748446

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PMC:6748446

Le document en format XML

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The cat is out of the bag: How parasites know their hosts

The cat is out of the bag: How parasites know their hosts

Source :

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki