Reversible cutaneous lymphoma occurring during methotrexate therapy
Identifieur interne : 002281 ( Istex/Curation ); précédent : 002280; suivant : 002282Reversible cutaneous lymphoma occurring during methotrexate therapy
Auteurs : R. Viraben [France] ; P. Brousse [France] ; L. Lamant [France]Source :
- British Journal of Dermatology [ 0007-0963 ] ; 1996-07.
Abstract
Summary A B‐cell lymphoma, restricted to the skin, developed in a 58‐year‐old man receiving methotrexate for non‐rheumatoid peripheral arthritis, with the simultaneous occurrence of a cytolytic hepatitis and carcinoma of the lung. Two weeks after methotrexate was stopped, both the skin tumour and the hepatitis disappeared spontaneously, with no recurrence during a 12‐month follow‐up period. Immunoglobulin gene rearrangement was shown by polymerase chain reaction (PCR) but in situ hybridization failed to reveal neoplastic cells positive for Epstein‐Barr virus (EBV).
Url:
DOI: 10.1046/j.1365-2133.1996.d01-946.x
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Reversible cutaneous lymphoma occurring during methotrexate therapy</title><author><name sortKey="Viraben, R" sort="Viraben, R" uniqKey="Viraben R" first="R." last="Viraben">R. Viraben</name><affiliation wicri:level="1"><mods:affiliation>Department of Dermatology, Purpan and La Grave Hospital, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Purpan and La Grave Hospital, Toulouse</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Correspondence address: Dr R. Viraben, Service de Dermatologie, Hopital La Grave, Place Lange, 31052 Toulouse Cedex, France.</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Correspondence address: Dr R. Viraben, Service de Dermatologie, Hopital La Grave, Place Lange, 31052 Toulouse Cedex</wicri:regionArea></affiliation></author><author><name sortKey="Brousse, P" sort="Brousse, P" uniqKey="Brousse P" first="P." last="Brousse">P. Brousse</name><affiliation wicri:level="1"><mods:affiliation>Department of Pathology, Purpan and La Grave Hospital, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pathology, Purpan and La Grave Hospital, Toulouse</wicri:regionArea></affiliation></author><author><name sortKey="Lamant, L" sort="Lamant, L" uniqKey="Lamant L" first="L." last="Lamant">L. Lamant</name><affiliation wicri:level="1"><mods:affiliation>Department of Pathology, Purpan and La Grave Hospital, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pathology, Purpan and La Grave Hospital, Toulouse</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BEE4962ABED858B5E2F9093D925804377F78D4E9</idno><date when="1996" year="1996">1996</date><idno type="doi">10.1046/j.1365-2133.1996.d01-946.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-1ZZMB2RV-C/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">002281</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002281</idno><idno type="wicri:Area/Istex/Curation">002281</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Reversible cutaneous lymphoma occurring during methotrexate therapy</title><author><name sortKey="Viraben, R" sort="Viraben, R" uniqKey="Viraben R" first="R." last="Viraben">R. Viraben</name><affiliation wicri:level="1"><mods:affiliation>Department of Dermatology, Purpan and La Grave Hospital, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Purpan and La Grave Hospital, Toulouse</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Correspondence address: Dr R. Viraben, Service de Dermatologie, Hopital La Grave, Place Lange, 31052 Toulouse Cedex, France.</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Correspondence address: Dr R. Viraben, Service de Dermatologie, Hopital La Grave, Place Lange, 31052 Toulouse Cedex</wicri:regionArea></affiliation></author><author><name sortKey="Brousse, P" sort="Brousse, P" uniqKey="Brousse P" first="P." last="Brousse">P. Brousse</name><affiliation wicri:level="1"><mods:affiliation>Department of Pathology, Purpan and La Grave Hospital, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pathology, Purpan and La Grave Hospital, Toulouse</wicri:regionArea></affiliation></author><author><name sortKey="Lamant, L" sort="Lamant, L" uniqKey="Lamant L" first="L." last="Lamant">L. Lamant</name><affiliation wicri:level="1"><mods:affiliation>Department of Pathology, Purpan and La Grave Hospital, Toulouse, France</mods:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Pathology, Purpan and La Grave Hospital, Toulouse</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">British Journal of Dermatology</title><title level="j" type="alt">BRITISH JOURNAL OF DERMATOLOGY</title><idno type="ISSN">0007-0963</idno><idno type="eISSN">1365-2133</idno><imprint><biblScope unit="vol">135</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="116">116</biblScope><biblScope unit="page" to="118">118</biblScope><biblScope unit="page-count">3</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1996-07">1996-07</date></imprint><idno type="ISSN">0007-0963</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0007-0963</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary A B‐cell lymphoma, restricted to the skin, developed in a 58‐year‐old man receiving methotrexate for non‐rheumatoid peripheral arthritis, with the simultaneous occurrence of a cytolytic hepatitis and carcinoma of the lung. Two weeks after methotrexate was stopped, both the skin tumour and the hepatitis disappeared spontaneously, with no recurrence during a 12‐month follow‐up period. Immunoglobulin gene rearrangement was shown by polymerase chain reaction (PCR) but in situ hybridization failed to reveal neoplastic cells positive for Epstein‐Barr virus (EBV).</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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