Phagocytosis in the normal and ischaemic retinal pigment epithelium of the rabbit
Identifieur interne : 001D19 ( Istex/Curation ); précédent : 001D18; suivant : 001D20Phagocytosis in the normal and ischaemic retinal pigment epithelium of the rabbit
Auteurs : N. F. Johnson [Royaume-Uni]Source :
- Experimental Eye Research [ 0014-4835 ] ; 1975.
English descriptors
- Teeft :
- Acute ischaemia, Average distribution, Cell bioz, Control tissue, Electron microscopy, Epithelium, Femoral artery, Holmes effect, Initial stages, Intraocular pressure, Ischaemia, Ischaemic, Ischaemic episode, Ischaemic tissue, Minutes ischaemia, Minutes recovery, Outer segment debris, Outer segment material, Outer segments, Percentage distribution, Peripheral retina, Periphery, Phagocytic, Phagocytic activity, Phagocytic capacity, Phagocytic process, Phagosome, Phagosome stages, Phagosomes, Pigment epithelium, Quantitative analysis, Rabbit retina, Recovery phase, Residual body, Retina, Retinal dystrophy, Retinal pigment epithelium, Rhesus monkey, Segment material, Short periods, Shorter period, Significant change, Similar regions, Test eyes, Turnover rate, Various phagosome stages, Visual cells, Visual streak.
Abstract
Abstract: A significant reduction in the number of phagosomes in the cells of the normal peripheral retinal pigment epithelium occurs as compared to the cells of the central region. In spite of this numerical difference the distribution of the various phagosome stages remained similar in the two locations. The tissue examined immediately after the various periods of ischaemia appeared similar to the control tissue in respect of the numbers and distribution of the phagosome stages. Recovery from short periods of ischaemia was associated with up to a three-fold increase in the initial stages of the phagocytic process. These changes were more marked in the peripheral retina and also with longer periods of recovery.
Url:
DOI: 10.1016/0014-4835(75)90147-5
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<author><name sortKey="Johnson, N F" sort="Johnson, N F" uniqKey="Johnson N" first="N. F." last="Johnson">N. F. Johnson</name>
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<profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acute ischaemia</term>
<term>Average distribution</term>
<term>Cell bioz</term>
<term>Control tissue</term>
<term>Electron microscopy</term>
<term>Epithelium</term>
<term>Femoral artery</term>
<term>Holmes effect</term>
<term>Initial stages</term>
<term>Intraocular pressure</term>
<term>Ischaemia</term>
<term>Ischaemic</term>
<term>Ischaemic episode</term>
<term>Ischaemic tissue</term>
<term>Minutes ischaemia</term>
<term>Minutes recovery</term>
<term>Outer segment debris</term>
<term>Outer segment material</term>
<term>Outer segments</term>
<term>Percentage distribution</term>
<term>Peripheral retina</term>
<term>Periphery</term>
<term>Phagocytic</term>
<term>Phagocytic activity</term>
<term>Phagocytic capacity</term>
<term>Phagocytic process</term>
<term>Phagosome</term>
<term>Phagosome stages</term>
<term>Phagosomes</term>
<term>Pigment epithelium</term>
<term>Quantitative analysis</term>
<term>Rabbit retina</term>
<term>Recovery phase</term>
<term>Residual body</term>
<term>Retina</term>
<term>Retinal dystrophy</term>
<term>Retinal pigment epithelium</term>
<term>Rhesus monkey</term>
<term>Segment material</term>
<term>Short periods</term>
<term>Shorter period</term>
<term>Significant change</term>
<term>Similar regions</term>
<term>Test eyes</term>
<term>Turnover rate</term>
<term>Various phagosome stages</term>
<term>Visual cells</term>
<term>Visual streak</term>
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<front><div type="abstract" xml:lang="en">Abstract: A significant reduction in the number of phagosomes in the cells of the normal peripheral retinal pigment epithelium occurs as compared to the cells of the central region. In spite of this numerical difference the distribution of the various phagosome stages remained similar in the two locations. The tissue examined immediately after the various periods of ischaemia appeared similar to the control tissue in respect of the numbers and distribution of the phagosome stages. Recovery from short periods of ischaemia was associated with up to a three-fold increase in the initial stages of the phagocytic process. These changes were more marked in the peripheral retina and also with longer periods of recovery.</div>
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