The localization of infective pre-erythrocytic forms of Plasmodium cynomolgi
Identifieur interne : 001C97 ( Istex/Curation ); précédent : 001C96; suivant : 001C98The localization of infective pre-erythrocytic forms of Plasmodium cynomolgi
Auteurs : Richard N. Rossan [États-Unis] ; Kathleen F. Fisher [États-Unis] ; Robert D. Greenland [États-Unis] ; Clara S. Genther [États-Unis] ; L. H. Schmidt [États-Unis]Source :
- Transactions of The Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 1964.
Abstract
1) This report deals with preliminary efforts to localize the site(s) of development of the pre-erythrocytic forms of P. cynomolgi by use of tissue implantation techniques. Twelve infant rhesus monkeys killed 4, 5, 6, and 7 days after inoculation with massive numbers of sporozoites served as donors of liver, spleen, lymph nodes, lung, and bone marrow. Fragments of these organs were implanted into the abdominal cavities of 115 subjects of the same species. 2) Positive results (development of parasitaemia) were obtained with 26 of 61 liver implants carried out 4–6 days after sporozoite inoculation. The incidence of takes was largest at 6 days, at which time the peripheral blood was still negative. None of 44 implants of spleen, lymph node, lung, or bone marrow induced infections. 3) These observations add strength to earlier morphological studies which have focussed attention on the liver as the site of development of pre-erythrocytic forms of primate plasmodia. Because of technical problems not yet resolved, they should not be interpreted as excluding the possibility that such development occurs in other organs.
Url:
DOI: 10.1016/0035-9203(64)90005-7
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001C97
Links to Exploration step
ISTEX:EBD65ED0F5CB1764DBE0B185AC6785E09FF9EDD3Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>The localization of infective pre-erythrocytic forms of Plasmodium cynomolgi</title><author><name sortKey="Rossan, Richard N" sort="Rossan, Richard N" uniqKey="Rossan R" first="Richard N." last="Rossan">Richard N. Rossan</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Fisher, Kathleen F" sort="Fisher, Kathleen F" uniqKey="Fisher K" first="Kathleen F." last="Fisher">Kathleen F. Fisher</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Greenland, Robert D" sort="Greenland, Robert D" uniqKey="Greenland R" first="Robert D." last="Greenland">Robert D. Greenland</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Genther, Clara S" sort="Genther, Clara S" uniqKey="Genther C" first="Clara S." last="Genther">Clara S. Genther</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, L H" sort="Schmidt, L H" uniqKey="Schmidt L" first="L. H." last="Schmidt">L. H. Schmidt</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:EBD65ED0F5CB1764DBE0B185AC6785E09FF9EDD3</idno><date when="1964" year="1964">1964</date><idno type="doi">10.1016/0035-9203(64)90005-7</idno><idno type="url">https://api.istex.fr/ark:/67375/HXZ-JVDC5CNS-C/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001C97</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001C97</idno><idno type="wicri:Area/Istex/Curation">001C97</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">The localization of infective pre-erythrocytic forms of <hi rend="italic">Plasmodium cynomolgi<ref type="fn" target="#fn1">☆</ref></hi></title><author><name sortKey="Rossan, Richard N" sort="Rossan, Richard N" uniqKey="Rossan R" first="Richard N." last="Rossan">Richard N. Rossan</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Fisher, Kathleen F" sort="Fisher, Kathleen F" uniqKey="Fisher K" first="Kathleen F." last="Fisher">Kathleen F. Fisher</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Greenland, Robert D" sort="Greenland, Robert D" uniqKey="Greenland R" first="Robert D." last="Greenland">Robert D. Greenland</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Genther, Clara S" sort="Genther, Clara S" uniqKey="Genther C" first="Clara S." last="Genther">Clara S. Genther</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author><author><name sortKey="Schmidt, L H" sort="Schmidt, L H" uniqKey="Schmidt L" first="L. H." last="Schmidt">L. H. Schmidt</name><affiliation wicri:level="1"><mods:affiliation>The Christ Hospital Institute of Medical Research, Cincinnati, Ohio USA</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>The Christ Hospital Institute of Medical Research, Cincinnati</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Transactions of The Royal Society of Tropical Medicine and Hygiene</title><title level="j" type="abbrev">Trans R Soc Trop Med Hyg</title><idno type="ISSN">0035-9203</idno><idno type="eISSN">1878-3503</idno><imprint><publisher>Royal Society of Tropical Medicine and Hygiene</publisher><date when="1964-03">1964</date><biblScope unit="vol">58</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="159">159</biblScope><biblScope unit="page" to="163">163</biblScope></imprint><idno type="ISSN">0035-9203</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0035-9203</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">1) This report deals with preliminary efforts to localize the site(s) of development of the pre-erythrocytic forms of P. cynomolgi by use of tissue implantation techniques. Twelve infant rhesus monkeys killed 4, 5, 6, and 7 days after inoculation with massive numbers of sporozoites served as donors of liver, spleen, lymph nodes, lung, and bone marrow. Fragments of these organs were implanted into the abdominal cavities of 115 subjects of the same species. 2) Positive results (development of parasitaemia) were obtained with 26 of 61 liver implants carried out 4–6 days after sporozoite inoculation. The incidence of takes was largest at 6 days, at which time the peripheral blood was still negative. None of 44 implants of spleen, lymph node, lung, or bone marrow induced infections. 3) These observations add strength to earlier morphological studies which have focussed attention on the liver as the site of development of pre-erythrocytic forms of primate plasmodia. Because of technical problems not yet resolved, they should not be interpreted as excluding the possibility that such development occurs in other organs.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C97 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 001C97 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:EBD65ED0F5CB1764DBE0B185AC6785E09FF9EDD3
|texte= The localization of infective pre-erythrocytic forms of Plasmodium cynomolgi
}}
| This area was generated with Dilib version V0.6.33. |  |