Prognostic risk factors and post mortem findings in cerebral malaria in children
Identifieur interne : 001268 ( Istex/Curation ); précédent : 001267; suivant : 001269Prognostic risk factors and post mortem findings in cerebral malaria in children
Auteurs : O. Walker [Nigeria] ; L. A. Salako [Nigeria] ; A. Sowunmi [Nigeria] ; J. O. Thomas [Nigeria] ; O. Sodeine [Nigeria] ; F. S. Bondi [Nigeria]Source :
- Transactions of The Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 1992.
Abstract
We have examined the possible risk factors for poor prognosis in cerebral malaria in 61 Nigerian children in an area of high malaria transmission. The level of coma, decerebrate rigidity, hypoglycaemia, and high urea levels were indicators of poor prognosis. Pyrexia, vomiting, and anaemia did not influence prognosis. Postmortem findings suggest gross cerebral oedema and raised intracranial pressure in 4 of 7 cases with petechial haemorrhages and small focal necrosis (Durck's granuloma).
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DOI: 10.1016/0035-9203(92)90082-N
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Walker</name><affiliation wicri:level="1"><mods:affiliation>Departments of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria</mods:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Departments of Pharmacology and Therapeutics, University of Ibadan, Ibadan</wicri:regionArea></affiliation><affiliation wicri:level="1"><mods:affiliation>Author for correspondence: Dr O. Walker, Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria.</mods:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Author for correspondence: Dr O. Walker, Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan</wicri:regionArea></affiliation></author><author><name sortKey="Salako, L A" sort="Salako, L A" uniqKey="Salako L" first="L. A." last="Salako">L. A. Salako</name><affiliation wicri:level="1"><mods:affiliation>Departments of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria</mods:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Departments of Pharmacology and Therapeutics, University of Ibadan, Ibadan</wicri:regionArea></affiliation></author><author><name sortKey="Sowunmi, A" sort="Sowunmi, A" uniqKey="Sowunmi A" first="A." last="Sowunmi">A. Sowunmi</name><affiliation wicri:level="1"><mods:affiliation>Departments of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria</mods:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Departments of Pharmacology and Therapeutics, University of Ibadan, Ibadan</wicri:regionArea></affiliation></author><author><name sortKey="Thomas, J O" sort="Thomas, J O" uniqKey="Thomas J" first="J. O." last="Thomas">J. O. Thomas</name><affiliation wicri:level="1"><mods:affiliation>Department of Pathology, University of Ibadan, Ibadan, Nigeria</mods:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Department of Pathology, University of Ibadan, Ibadan</wicri:regionArea></affiliation></author><author><name sortKey="Sodeine, O" sort="Sodeine, O" uniqKey="Sodeine O" first="O." last="Sodeine">O. Sodeine</name><affiliation wicri:level="1"><mods:affiliation>Department of Paediatrics, University of Ibadan, Ibadan, Nigeria</mods:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Department of Paediatrics, University of Ibadan, Ibadan</wicri:regionArea></affiliation></author><author><name sortKey="Bondi, F S" sort="Bondi, F S" uniqKey="Bondi F" first="F. S." last="Bondi">F. S. Bondi</name><affiliation wicri:level="1"><mods:affiliation>Department of Paediatrics, University of Ibadan, Ibadan, Nigeria</mods:affiliation><country xml:lang="fr">Nigeria</country><wicri:regionArea>Department of Paediatrics, University of Ibadan, Ibadan</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Transactions of The Royal Society of Tropical Medicine and Hygiene</title><title level="j" type="abbrev">Trans R Soc Trop Med Hyg</title><idno type="ISSN">0035-9203</idno><idno type="eISSN">1878-3503</idno><imprint><publisher>Royal Society of Tropical Medicine and Hygiene</publisher><date when="1992-09">1992</date><biblScope unit="vol">86</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="491">491</biblScope><biblScope unit="page" to="493">493</biblScope></imprint><idno type="ISSN">0035-9203</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0035-9203</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">We have examined the possible risk factors for poor prognosis in cerebral malaria in 61 Nigerian children in an area of high malaria transmission. The level of coma, decerebrate rigidity, hypoglycaemia, and high urea levels were indicators of poor prognosis. Pyrexia, vomiting, and anaemia did not influence prognosis. Postmortem findings suggest gross cerebral oedema and raised intracranial pressure in 4 of 7 cases with petechial haemorrhages and small focal necrosis (Durck's granuloma).</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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