Toxicology of Sensory Systems: A Perspective
Identifieur interne : 000E43 ( Istex/Curation ); précédent : 000E42; suivant : 000E44Toxicology of Sensory Systems: A Perspective
Auteurs : E. A. Lock [Royaume-Uni] ; E. S. Harpur [Royaume-Uni]Source :
- Human & Experimental Toxicology [ 0960-3271 ] ; 1992-11.
English descriptors
- Teeft :
- Acta otolaryngologica, Airflow, Alderley park, Aminoglycoside, Aminoglycoside antibiotics, Animal models, Aran, Carbon monoxide, Cochlea, Cochlear, Critical reviews, Cutaneous sensation, Cytochrome, Drug metabolism, Drug metabolizing enzymes, Environmental health perspectives, Epithelium, Ethacrynic acid, Exhaustive list, Experimental animals, Functional deficit, Gentamicin, Guinea, Guinea pigs, Hair cells, Hearing function, Hearing research, High dosage, High doses, Lesion, Many years, Metabolism, Model system, Nasal, Nasal cavity, Nasal cytochrome, Nasal cytochromes, Nasal epithelium, Nasal lesions, Nasal passages, Nasal tissue, Neurosensory epithelium, Ocular toxicity, Ohcs, Olfactory, Olfactory epithelium, Olfactory toxicity, Ototoxic, Ototoxic aminoglycoside antibiotic, Ototoxic chemicals, Ototoxic drugs, Ototoxic effects, Ototoxicity, Peripheral sensation, Permanent loss, Professor aran, Professor blain, Respiratory epithelium, Retina, Rhesus monkeys, Selective toxicity, Single dose, Species differences, Sterling winthrop research centre, Stria vascularis, Term ototoxicity, Toxicity, Toxicology, Vestibular, Vestibular function, Vestibular system, Wide range.
Abstract
This brief review is the result of a recent meeting of the British Toxicology Society (Toxicology of Sensory Systems, University of York, April 2-3, 1992). The meeting provided the opportunity to discuss the anatomy, physiology and function of the eye, ear, nasal epithelium and peripheral sensation and the methods that are available to detect injury or dysfunction both in the preclinical and clinical situation. In addition, the mechanism whereby certain chemicals can perturb some of these organs was discussed. The aim of this short article is to highlight some of the recent advances in understanding in these areas with regard to their relevance or impact on toxicology. For convenience the areas will be discussed under separate headings.
Url:
DOI: 10.1177/096032719201100602
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<term>Airflow</term>
<term>Alderley park</term>
<term>Aminoglycoside</term>
<term>Aminoglycoside antibiotics</term>
<term>Animal models</term>
<term>Aran</term>
<term>Carbon monoxide</term>
<term>Cochlea</term>
<term>Cochlear</term>
<term>Critical reviews</term>
<term>Cutaneous sensation</term>
<term>Cytochrome</term>
<term>Drug metabolism</term>
<term>Drug metabolizing enzymes</term>
<term>Environmental health perspectives</term>
<term>Epithelium</term>
<term>Ethacrynic acid</term>
<term>Exhaustive list</term>
<term>Experimental animals</term>
<term>Functional deficit</term>
<term>Gentamicin</term>
<term>Guinea</term>
<term>Guinea pigs</term>
<term>Hair cells</term>
<term>Hearing function</term>
<term>Hearing research</term>
<term>High dosage</term>
<term>High doses</term>
<term>Lesion</term>
<term>Many years</term>
<term>Metabolism</term>
<term>Model system</term>
<term>Nasal</term>
<term>Nasal cavity</term>
<term>Nasal cytochrome</term>
<term>Nasal cytochromes</term>
<term>Nasal epithelium</term>
<term>Nasal lesions</term>
<term>Nasal passages</term>
<term>Nasal tissue</term>
<term>Neurosensory epithelium</term>
<term>Ocular toxicity</term>
<term>Ohcs</term>
<term>Olfactory</term>
<term>Olfactory epithelium</term>
<term>Olfactory toxicity</term>
<term>Ototoxic</term>
<term>Ototoxic aminoglycoside antibiotic</term>
<term>Ototoxic chemicals</term>
<term>Ototoxic drugs</term>
<term>Ototoxic effects</term>
<term>Ototoxicity</term>
<term>Peripheral sensation</term>
<term>Permanent loss</term>
<term>Professor aran</term>
<term>Professor blain</term>
<term>Respiratory epithelium</term>
<term>Retina</term>
<term>Rhesus monkeys</term>
<term>Selective toxicity</term>
<term>Single dose</term>
<term>Species differences</term>
<term>Sterling winthrop research centre</term>
<term>Stria vascularis</term>
<term>Term ototoxicity</term>
<term>Toxicity</term>
<term>Toxicology</term>
<term>Vestibular</term>
<term>Vestibular function</term>
<term>Vestibular system</term>
<term>Wide range</term>
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<front><div type="abstract" xml:lang="en">This brief review is the result of a recent meeting of the British Toxicology Society (Toxicology of Sensory Systems, University of York, April 2-3, 1992). The meeting provided the opportunity to discuss the anatomy, physiology and function of the eye, ear, nasal epithelium and peripheral sensation and the methods that are available to detect injury or dysfunction both in the preclinical and clinical situation. In addition, the mechanism whereby certain chemicals can perturb some of these organs was discussed. The aim of this short article is to highlight some of the recent advances in understanding in these areas with regard to their relevance or impact on toxicology. For convenience the areas will be discussed under separate headings.</div>
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