Radionuclide approach to tumor detection
Identifieur interne : 000814 ( Istex/Curation ); précédent : 000813; suivant : 000815Radionuclide approach to tumor detection
Auteurs : John L. Espinosa [États-Unis] ; Gerald S. Johnston [États-Unis]Source :
- Journal of Surgical Oncology [ 0022-4790 ] ; 1971.
English descriptors
- Teeft :
- Acta unio intern, Antifibrinogen, Bone lesions, Bone tumors, Cerebrovascular lesions, Chloroquine, Contra cancrum, Focal defect, Human fibrinogen, Human patients, Human tumors, Lesion, Malignant melanomas, Melanin pigment, Melanoma, Metabolic activity, Neoplastic, Neoplastic tissue, Nucl, Nuclear medicine, Pancreas, Pancreatic, Pancreatic disease, Pancreatic scanning, Positive scans, Preliminary note, Radioactive material, Radioactive phosphorus, Radioiodinated quinoline derivatives, Radionuclide, Radionuclide approach, Scanning, Scanning tumors, Selective concentration, Selenite, Tumor, Tumor detection, Useful agent.
Abstract
A considerable amount of the nuclear medicine physician's attention is directed toward the screening of patients for tumor diagnosis or for the growth or metastasis of known tumor. Two basic techniques of radionuclide tumor detection are (1) rendering the normal tissue in an organ radioactive and looking for abnormal, nonradioactive areas which represent tumor involvement and (2) making the tumor itself radioactive and hence readily detectable in the relatively nonradioactive normal tissue. Liver, kidney, and thyroid scanning utilize the first method, while metastatic thyroid, brain, and bone tumor scans are examples of the second. The superiority of the technique for finding a hot or bright lesion in a cold or dark background has prompted attempts at extension of this method to the search for tumors. Among the newer agents which specifically label tumors and are being evaluated are Ga67‐citrate in lung carcinomas and lymphomas, Se75‐selenite in brain and bone tumors, radioiodinated antifibrinogen for various tumors, and radioiodinated iodoquine in malignant melanoma.
Url:
DOI: 10.1002/jso.2930030604
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Johnston</name><affiliation wicri:level="2"><mods:affiliation>Nuclear Medicine Service, Letterman General Hospital, The Presidio of San Francisco, San Francisco, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Nuclear Medicine Service, Letterman General Hospital, The Presidio of San Francisco, San Francisco</wicri:cityArea></affiliation><affiliation wicri:level="2"><mods:affiliation>Current Address: Director, Department of Nuclear Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Current Address: Director, Department of Nuclear Medicine, Clinical Center, National Institutes of Health, Bethesda</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:0F63328BA2755A6BDACA233DEB9B66012B3E731B</idno><date when="1971" year="1971">1971</date><idno type="doi">10.1002/jso.2930030604</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-JVZ8GSPL-6/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000814</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000814</idno><idno type="wicri:Area/Istex/Curation">000814</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Radionuclide approach to tumor detection</title><author><name sortKey="Espinosa, John L" sort="Espinosa, John L" uniqKey="Espinosa J" first="John L." last="Espinosa">John L. 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Johnston</name><affiliation wicri:level="2"><mods:affiliation>Nuclear Medicine Service, Letterman General Hospital, The Presidio of San Francisco, San Francisco, California</mods:affiliation><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Nuclear Medicine Service, Letterman General Hospital, The Presidio of San Francisco, San Francisco</wicri:cityArea></affiliation><affiliation wicri:level="2"><mods:affiliation>Current Address: Director, Department of Nuclear Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland</mods:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Current Address: Director, Department of Nuclear Medicine, Clinical Center, National Institutes of Health, Bethesda</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Surgical Oncology</title><title level="j" type="alt">JOURNAL OF SURGICAL ONCOLOGY</title><idno type="ISSN">0022-4790</idno><idno type="eISSN">1096-9098</idno><imprint><biblScope unit="vol">3</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="587">587</biblScope><biblScope unit="page" to="592">592</biblScope><biblScope unit="page-count">6</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>New York</pubPlace><date type="published" when="1971">1971</date></imprint><idno type="ISSN">0022-4790</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-4790</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acta unio intern</term><term>Antifibrinogen</term><term>Bone lesions</term><term>Bone tumors</term><term>Cerebrovascular lesions</term><term>Chloroquine</term><term>Contra cancrum</term><term>Focal defect</term><term>Human fibrinogen</term><term>Human patients</term><term>Human tumors</term><term>Lesion</term><term>Malignant melanomas</term><term>Melanin pigment</term><term>Melanoma</term><term>Metabolic activity</term><term>Neoplastic</term><term>Neoplastic tissue</term><term>Nucl</term><term>Nuclear medicine</term><term>Pancreas</term><term>Pancreatic</term><term>Pancreatic disease</term><term>Pancreatic scanning</term><term>Positive scans</term><term>Preliminary note</term><term>Radioactive material</term><term>Radioactive phosphorus</term><term>Radioiodinated quinoline derivatives</term><term>Radionuclide</term><term>Radionuclide approach</term><term>Scanning</term><term>Scanning tumors</term><term>Selective concentration</term><term>Selenite</term><term>Tumor</term><term>Tumor detection</term><term>Useful agent</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A considerable amount of the nuclear medicine physician's attention is directed toward the screening of patients for tumor diagnosis or for the growth or metastasis of known tumor. Two basic techniques of radionuclide tumor detection are (1) rendering the normal tissue in an organ radioactive and looking for abnormal, nonradioactive areas which represent tumor involvement and (2) making the tumor itself radioactive and hence readily detectable in the relatively nonradioactive normal tissue. Liver, kidney, and thyroid scanning utilize the first method, while metastatic thyroid, brain, and bone tumor scans are examples of the second. The superiority of the technique for finding a hot or bright lesion in a cold or dark background has prompted attempts at extension of this method to the search for tumors. Among the newer agents which specifically label tumors and are being evaluated are Ga67‐citrate in lung carcinomas and lymphomas, Se75‐selenite in brain and bone tumors, radioiodinated antifibrinogen for various tumors, and radioiodinated iodoquine in malignant melanoma.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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