Selective C4 deficiency, systemic lupus erythematosus, and Whipple's disease.
Identifieur interne : 002800 ( Istex/Corpus ); précédent : 002799; suivant : 002801Selective C4 deficiency, systemic lupus erythematosus, and Whipple's disease.
Auteurs : M. Ehrenfeld ; M B Urowitz ; M E PlattsSource :
- Annals of the Rheumatic Diseases [ 0003-4967 ] ; 1984-02.
English descriptors
- Teeft :
- Abdominal pain, Antibiotic therapy, Bacillary, Bacillary bodies, Bowel, Case report, Complement deficiency, Electron microscopy, Erythematosus, Foamy macrophages, Gastrointestinal, Gastrointestinal symptoms, Gastrointestinal tract, Intraepithelial lymphocytes, Laboratory investigations, Lamina, Lamina propria, Large numbers, Lupus, Lymph, Lymph node, Lymph nodes, Macrophage, Mast cells, Node, Opportunistic infection, Polyserositis, Propria, Rash, Selective deficiency, Systemic, Systemic disease, Systemic lupus erythematosus, Typical bacillary bodies, Urowitz, Wellesley hospital.
Abstract
A 45-year-old female with selective deficiency of C4 and systemic lupus erythematosus developed puzzling gastrointestinal and systemic symptoms in the last 6 months of her life. Extensive investigation of the gastrointestinal tract did not yield any diagnosis, and the patient died shortly afterwards. Autopsy revealed evidence of a typical Whipple's disease of the jejunum and lymph nodes. This association has not been previously described. The disease is reviewed with emphasis on its being an opportunistic infection in an immunosuppressed host with a complement deficiency and SLE.
Url:
DOI: 10.1136/ard.43.1.91
Links to Exploration step
ISTEX:D49AA7BA93C6CB417A0F0E052A564289DE6972FBLe document en format XML
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Ehrenfeld</name></author><author><name sortKey="Urowitz, M B" sort="Urowitz, M B" uniqKey="Urowitz M" first="M B" last="Urowitz">M B Urowitz</name></author><author><name sortKey="Platts, M E" sort="Platts, M E" uniqKey="Platts M" first="M E" last="Platts">M E Platts</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D49AA7BA93C6CB417A0F0E052A564289DE6972FB</idno><date when="1984" year="1984">1984</date><idno type="doi">10.1136/ard.43.1.91</idno><idno type="url">https://api.istex.fr/ark:/67375/NVC-16KH7T2V-T/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">002800</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002800</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Selective C4 deficiency, systemic lupus erythematosus, and Whipple's disease.</title><author><name sortKey="Ehrenfeld, M" sort="Ehrenfeld, M" uniqKey="Ehrenfeld M" first="M" last="Ehrenfeld">M. Ehrenfeld</name></author><author><name sortKey="Urowitz, M B" sort="Urowitz, M B" uniqKey="Urowitz M" first="M B" last="Urowitz">M B Urowitz</name></author><author><name sortKey="Platts, M E" sort="Platts, M E" uniqKey="Platts M" first="M E" last="Platts">M E Platts</name></author></analytic><monogr></monogr><series><title level="j">Annals of the Rheumatic Diseases</title><title level="j" type="abbrev">Ann Rheum Dis</title><idno type="ISSN">0003-4967</idno><idno type="eISSN">1468-2060</idno><imprint><publisher>BMJ Publishing Group Ltd and European League Against Rheumatism</publisher><date type="published" when="1984-02">1984-02</date><biblScope unit="volume">43</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="91">91</biblScope></imprint><idno type="ISSN">0003-4967</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0003-4967</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Abdominal pain</term><term>Antibiotic therapy</term><term>Bacillary</term><term>Bacillary bodies</term><term>Bowel</term><term>Case report</term><term>Complement deficiency</term><term>Electron microscopy</term><term>Erythematosus</term><term>Foamy macrophages</term><term>Gastrointestinal</term><term>Gastrointestinal symptoms</term><term>Gastrointestinal tract</term><term>Intraepithelial lymphocytes</term><term>Laboratory investigations</term><term>Lamina</term><term>Lamina propria</term><term>Large numbers</term><term>Lupus</term><term>Lymph</term><term>Lymph node</term><term>Lymph nodes</term><term>Macrophage</term><term>Mast cells</term><term>Node</term><term>Opportunistic infection</term><term>Polyserositis</term><term>Propria</term><term>Rash</term><term>Selective deficiency</term><term>Systemic</term><term>Systemic disease</term><term>Systemic lupus erythematosus</term><term>Typical bacillary bodies</term><term>Urowitz</term><term>Wellesley hospital</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 45-year-old female with selective deficiency of C4 and systemic lupus erythematosus developed puzzling gastrointestinal and systemic symptoms in the last 6 months of her life. Extensive investigation of the gastrointestinal tract did not yield any diagnosis, and the patient died shortly afterwards. Autopsy revealed evidence of a typical Whipple's disease of the jejunum and lymph nodes. This association has not been previously described. 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Extensive investigation of the gastrointestinal tract did not yield any diagnosis, and the patient died shortly afterwards. Autopsy revealed evidence of a typical Whipple's disease of the jejunum and lymph nodes. This association has not been previously described. The disease is reviewed with emphasis on its being an opportunistic infection in an immunosuppressed host with a complement deficiency and SLE.</p></abstract></profileDesc><revisionDesc><change when="1984-02-01">Created</change><change when="1984-02">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2017-10-17">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/NVC-16KH7T2V-T/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus bmj" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="no"</istex:xmlDeclaration><istex:docType PUBLIC="-//NLM//DTD Journal Archiving and Interchange DTD v2.3 20070202//EN" URI="archivearticle.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article" xml:lang="EN"><front><journal-meta><journal-id journal-id-type="hwp">annrheumdis</journal-id><journal-id journal-id-type="nlm-ta">Ann Rheum Dis</journal-id><journal-title>Annals of the Rheumatic Diseases</journal-title><abbrev-journal-title abbrev-type="publisher">Ann Rheum Dis</abbrev-journal-title><issn pub-type="ppub">0003-4967</issn><issn pub-type="epub">1468-2060</issn><publisher><publisher-name>BMJ Publishing Group Ltd and European League Against Rheumatism</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">6198977</article-id><article-id pub-id-type="other">annrheumdis;43/1/91</article-id><article-id pub-id-type="doi">10.1136/ard.43.1.91</article-id><article-id pub-id-type="other">91</article-id><article-id pub-id-type="other">ard.43.1.91</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Selective C4 deficiency, systemic lupus erythematosus, and Whipple's disease.</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ehrenfeld</surname><given-names>M</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Urowitz</surname><given-names>M B</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Platts</surname><given-names>M E</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><month>2</month><year>1984</year></pub-date><pub-date pub-type="epub"><day>1</day><month>2</month><year>1984</year></pub-date><volume>43</volume><volume-id pub-id-type="other">43</volume-id><volume-id pub-id-type="other">43</volume-id><issue>1</issue><issue-id pub-id-type="other">annrheumdis;43/1</issue-id><issue-id pub-id-type="other">1</issue-id><issue-id pub-id-type="other">43/1</issue-id><fpage>91</fpage><self-uri content-type="pdf" xlink:role="full-text" xlink:href="annrheumdis-43-91.pdf"></self-uri><abstract><p>A 45-year-old female with selective deficiency of C4 and systemic lupus erythematosus developed puzzling gastrointestinal and systemic symptoms in the last 6 months of her life. Extensive investigation of the gastrointestinal tract did not yield any diagnosis, and the patient died shortly afterwards. Autopsy revealed evidence of a typical Whipple's disease of the jejunum and lymph nodes. This association has not been previously described. The disease is reviewed with emphasis on its being an opportunistic infection in an immunosuppressed host with a complement deficiency and SLE.</p></abstract></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Selective C4 deficiency, systemic lupus erythematosus, and Whipple's disease.</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Selective C4 deficiency, systemic lupus erythematosus, and Whipple's disease.</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Ehrenfeld</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M B</namePart><namePart type="family">Urowitz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M E</namePart><namePart type="family">Platts</namePart><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>BMJ Publishing Group Ltd and European League Against Rheumatism</publisher><dateIssued encoding="w3cdtf">1984-02</dateIssued><dateCreated encoding="w3cdtf">1984-02-01</dateCreated><copyrightDate encoding="w3cdtf">1984</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><abstract lang="en">A 45-year-old female with selective deficiency of C4 and systemic lupus erythematosus developed puzzling gastrointestinal and systemic symptoms in the last 6 months of her life. Extensive investigation of the gastrointestinal tract did not yield any diagnosis, and the patient died shortly afterwards. Autopsy revealed evidence of a typical Whipple's disease of the jejunum and lymph nodes. This association has not been previously described. 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