Hyper-IgE syndrome and autoimmunity in Mexican children
Identifieur interne : 002644 ( Istex/Corpus ); précédent : 002643; suivant : 002645Hyper-IgE syndrome and autoimmunity in Mexican children
Auteurs : Marco Yamazaki-Nakashimada ; Samuel Zaltzman-Girshevich ; Silvestre Garcia De La Puente ; Beatriz De Leon-Bojorge ; Sara Espinosa-Padilla ; Marimar Saez-De-Ocariz ; Daniel Carrasco-Daza ; Victor Hernandez-Bautista ; Lorenzo Pérez-Fernandez ; Francisco Espinosa-RosalesSource :
- Pediatric Nephrology [ 0931-041X ] ; 2006-08-01.
English descriptors
- KwdEn :
Abstract
Abstract: Hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by recurrent skin abscesses, recurrent pneumonia with pneumatocele formation, eczema, eosinophilia, and elevated levels of serum IgE. Patients with the autosomal recessive (AR) form of HIES appear to be prone to developing autoimmune diseases. We present two cases of HIES with autoimmune complications; one case was a product of a consanguineous marriage, the other one was a sporadic case. The first patient presented with recurrent episodes of erythema nodosum, warts, bronchiolitis obliterans and thrombocytopenia. The second patient developed glomerulonephritis resulting in endstage renal failure. She later developed malar rash, oral ulcers, cerebral infarcts with vasculitis and positive ANA, anti-dsDNA, and antiphospholipid antibodies. We discuss the dilemma in treating patients who present with both primary immunodeficiency and autoimmunity.
Url:
DOI: 10.1007/s00467-006-0178-3
Links to Exploration step
ISTEX:E4BE8B4C919BB11C12FE2244E7B435CE7FC58112Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Hyper-IgE syndrome and autoimmunity in Mexican children</title><author><name sortKey="Yamazaki Nakashimada, Marco" sort="Yamazaki Nakashimada, Marco" uniqKey="Yamazaki Nakashimada M" first="Marco" last="Yamazaki-Nakashimada">Marco Yamazaki-Nakashimada</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: yzki71@yahoo.com.mx</mods:affiliation></affiliation></author><author><name sortKey="Zaltzman Girshevich, Samuel" sort="Zaltzman Girshevich, Samuel" uniqKey="Zaltzman Girshevich S" first="Samuel" last="Zaltzman-Girshevich">Samuel Zaltzman-Girshevich</name><affiliation><mods:affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Garcia De La Puente, Silvestre" sort="Garcia De La Puente, Silvestre" uniqKey="Garcia De La Puente S" first="Silvestre" last="Garcia De La Puente">Silvestre Garcia De La Puente</name><affiliation><mods:affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="De Leon Bojorge, Beatriz" sort="De Leon Bojorge, Beatriz" uniqKey="De Leon Bojorge B" first="Beatriz" last="De Leon-Bojorge">Beatriz De Leon-Bojorge</name><affiliation><mods:affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Espinosa Padilla, Sara" sort="Espinosa Padilla, Sara" uniqKey="Espinosa Padilla S" first="Sara" last="Espinosa-Padilla">Sara Espinosa-Padilla</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Saez De Ocariz, Marimar" sort="Saez De Ocariz, Marimar" uniqKey="Saez De Ocariz M" first="Marimar" last="Saez-De-Ocariz">Marimar Saez-De-Ocariz</name><affiliation><mods:affiliation>Department of Dermatology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Carrasco Daza, Daniel" sort="Carrasco Daza, Daniel" uniqKey="Carrasco Daza D" first="Daniel" last="Carrasco-Daza">Daniel Carrasco-Daza</name><affiliation><mods:affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Hernandez Bautista, Victor" sort="Hernandez Bautista, Victor" uniqKey="Hernandez Bautista V" first="Victor" last="Hernandez-Bautista">Victor Hernandez-Bautista</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Perez Fernandez, Lorenzo" sort="Perez Fernandez, Lorenzo" uniqKey="Perez Fernandez L" first="Lorenzo" last="Pérez-Fernandez">Lorenzo Pérez-Fernandez</name><affiliation><mods:affiliation>Department of Pulmonology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Espinosa Rosales, Francisco" sort="Espinosa Rosales, Francisco" uniqKey="Espinosa Rosales F" first="Francisco" last="Espinosa-Rosales">Francisco Espinosa-Rosales</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:E4BE8B4C919BB11C12FE2244E7B435CE7FC58112</idno><date when="2006" year="2006">2006</date><idno type="doi">10.1007/s00467-006-0178-3</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-R7NHRMND-S/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">002644</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002644</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Hyper-IgE syndrome and autoimmunity in Mexican children</title><author><name sortKey="Yamazaki Nakashimada, Marco" sort="Yamazaki Nakashimada, Marco" uniqKey="Yamazaki Nakashimada M" first="Marco" last="Yamazaki-Nakashimada">Marco Yamazaki-Nakashimada</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: yzki71@yahoo.com.mx</mods:affiliation></affiliation></author><author><name sortKey="Zaltzman Girshevich, Samuel" sort="Zaltzman Girshevich, Samuel" uniqKey="Zaltzman Girshevich S" first="Samuel" last="Zaltzman-Girshevich">Samuel Zaltzman-Girshevich</name><affiliation><mods:affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Garcia De La Puente, Silvestre" sort="Garcia De La Puente, Silvestre" uniqKey="Garcia De La Puente S" first="Silvestre" last="Garcia De La Puente">Silvestre Garcia De La Puente</name><affiliation><mods:affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="De Leon Bojorge, Beatriz" sort="De Leon Bojorge, Beatriz" uniqKey="De Leon Bojorge B" first="Beatriz" last="De Leon-Bojorge">Beatriz De Leon-Bojorge</name><affiliation><mods:affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Espinosa Padilla, Sara" sort="Espinosa Padilla, Sara" uniqKey="Espinosa Padilla S" first="Sara" last="Espinosa-Padilla">Sara Espinosa-Padilla</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Saez De Ocariz, Marimar" sort="Saez De Ocariz, Marimar" uniqKey="Saez De Ocariz M" first="Marimar" last="Saez-De-Ocariz">Marimar Saez-De-Ocariz</name><affiliation><mods:affiliation>Department of Dermatology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Carrasco Daza, Daniel" sort="Carrasco Daza, Daniel" uniqKey="Carrasco Daza D" first="Daniel" last="Carrasco-Daza">Daniel Carrasco-Daza</name><affiliation><mods:affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Hernandez Bautista, Victor" sort="Hernandez Bautista, Victor" uniqKey="Hernandez Bautista V" first="Victor" last="Hernandez-Bautista">Victor Hernandez-Bautista</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Perez Fernandez, Lorenzo" sort="Perez Fernandez, Lorenzo" uniqKey="Perez Fernandez L" first="Lorenzo" last="Pérez-Fernandez">Lorenzo Pérez-Fernandez</name><affiliation><mods:affiliation>Department of Pulmonology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author><author><name sortKey="Espinosa Rosales, Francisco" sort="Espinosa Rosales, Francisco" uniqKey="Espinosa Rosales F" first="Francisco" last="Espinosa-Rosales">Francisco Espinosa-Rosales</name><affiliation><mods:affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Pediatric Nephrology</title><title level="j" type="sub">Journal of the International Pediatric Nephrology Association</title><title level="j" type="abbrev">Pediatr Nephrol</title><idno type="ISSN">0931-041X</idno><idno type="eISSN">1432-198X</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="2006-08-01">2006-08-01</date><biblScope unit="volume">21</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="1200">1200</biblScope><biblScope unit="page" to="1205">1205</biblScope></imprint><idno type="ISSN">0931-041X</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0931-041X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiphospholipid syndrome</term><term>Autoimmunity</term><term>CNS vasculitis</term><term>Hyper-IgE syndrome</term><term>Primary immunodeficiency</term><term>Systemic lupus erythematosus</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by recurrent skin abscesses, recurrent pneumonia with pneumatocele formation, eczema, eosinophilia, and elevated levels of serum IgE. Patients with the autosomal recessive (AR) form of HIES appear to be prone to developing autoimmune diseases. We present two cases of HIES with autoimmune complications; one case was a product of a consanguineous marriage, the other one was a sporadic case. The first patient presented with recurrent episodes of erythema nodosum, warts, bronchiolitis obliterans and thrombocytopenia. The second patient developed glomerulonephritis resulting in endstage renal failure. She later developed malar rash, oral ulcers, cerebral infarcts with vasculitis and positive ANA, anti-dsDNA, and antiphospholipid antibodies. We discuss the dilemma in treating patients who present with both primary immunodeficiency and autoimmunity.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>Marco Yamazaki-Nakashimada</name><affiliations><json:string>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string><json:string>E-mail: yzki71@yahoo.com.mx</json:string></affiliations></json:item><json:item><name>Samuel Zaltzman-Girshevich</name><affiliations><json:string>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Silvestre Garcia de la Puente</name><affiliations><json:string>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Beatriz De Leon-Bojorge</name><affiliations><json:string>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Sara Espinosa-Padilla</name><affiliations><json:string>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Marimar Saez-de-Ocariz</name><affiliations><json:string>Department of Dermatology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Daniel Carrasco-Daza</name><affiliations><json:string>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Victor Hernandez-Bautista</name><affiliations><json:string>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Lorenzo Pérez-Fernandez</name><affiliations><json:string>Department of Pulmonology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item><json:item><name>Francisco Espinosa-Rosales</name><affiliations><json:string>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Systemic lupus erythematosus</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Antiphospholipid syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Hyper-IgE syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Autoimmunity</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Primary immunodeficiency</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>CNS vasculitis</value></json:item></subject><articleId><json:string>178</json:string><json:string>s00467-006-0178-3</json:string></articleId><arkIstex>ark:/67375/VQC-R7NHRMND-S</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>BriefCommunication</json:string></originalGenre><abstract>Abstract: Hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by recurrent skin abscesses, recurrent pneumonia with pneumatocele formation, eczema, eosinophilia, and elevated levels of serum IgE. Patients with the autosomal recessive (AR) form of HIES appear to be prone to developing autoimmune diseases. We present two cases of HIES with autoimmune complications; one case was a product of a consanguineous marriage, the other one was a sporadic case. The first patient presented with recurrent episodes of erythema nodosum, warts, bronchiolitis obliterans and thrombocytopenia. The second patient developed glomerulonephritis resulting in endstage renal failure. She later developed malar rash, oral ulcers, cerebral infarcts with vasculitis and positive ANA, anti-dsDNA, and antiphospholipid antibodies. We discuss the dilemma in treating patients who present with both primary immunodeficiency and autoimmunity.</abstract><qualityIndicators><score>6.889</score><pdfWordCount>3377</pdfWordCount><pdfCharCount>23768</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>6</pdfPageCount><pdfPageSize>595.276 x 785.197 pts</pdfPageSize><refBibsNative>false</refBibsNative><abstractWordCount>126</abstractWordCount><abstractCharCount>934</abstractCharCount><keywordCount>6</keywordCount></qualityIndicators><title>Hyper-IgE syndrome and autoimmunity in Mexican children</title><genre><json:string>brief-communication</json:string></genre><host><title>Pediatric Nephrology</title><language><json:string>unknown</json:string></language><publicationDate>2006</publicationDate><copyrightDate>2006</copyrightDate><issn><json:string>0931-041X</json:string></issn><eissn><json:string>1432-198X</json:string></eissn><journalId><json:string>467</json:string></journalId><volume>21</volume><issue>8</issue><pages><first>1200</first><last>1205</last></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Pediatrics</value></json:item></subject></host><ark><json:string>ark:/67375/VQC-R7NHRMND-S</json:string></ark><publicationDate>2006</publicationDate><copyrightDate>2006</copyrightDate><doi><json:string>10.1007/s00467-006-0178-3</json:string></doi><id>E4BE8B4C919BB11C12FE2244E7B435CE7FC58112</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-R7NHRMND-S/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-R7NHRMND-S/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/VQC-R7NHRMND-S/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Hyper-IgE syndrome and autoimmunity in Mexican children</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://scientific-publisher.data.istex.fr">Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><availability><licence><p>IPNA, 2006</p></licence><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</p></availability><date>2005-09-19</date></publicationStmt><notesStmt><note type="brief-communication" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-S9SX2MFS-0">brief-communication</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note><note>Brief Report</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Hyper-IgE syndrome and autoimmunity in Mexican children</title><author xml:id="author-0000" corresp="yes"><persName><forename type="first">Marco</forename><surname>Yamazaki-Nakashimada</surname></persName><email>yzki71@yahoo.com.mx</email><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Samuel</forename><surname>Zaltzman-Girshevich</surname></persName><affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Silvestre</forename><surname>Garcia de la Puente</surname></persName><affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Beatriz</forename><surname>De Leon-Bojorge</surname></persName><affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Sara</forename><surname>Espinosa-Padilla</surname></persName><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Marimar</forename><surname>Saez-de-Ocariz</surname></persName><affiliation>Department of Dermatology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0006"><persName><forename type="first">Daniel</forename><surname>Carrasco-Daza</surname></persName><affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0007"><persName><forename type="first">Victor</forename><surname>Hernandez-Bautista</surname></persName><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0008"><persName><forename type="first">Lorenzo</forename><surname>Pérez-Fernandez</surname></persName><affiliation>Department of Pulmonology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><author xml:id="author-0009"><persName><forename type="first">Francisco</forename><surname>Espinosa-Rosales</surname></persName><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation></author><idno type="istex">E4BE8B4C919BB11C12FE2244E7B435CE7FC58112</idno><idno type="ark">ark:/67375/VQC-R7NHRMND-S</idno><idno type="DOI">10.1007/s00467-006-0178-3</idno><idno type="article-id">178</idno><idno type="article-id">s00467-006-0178-3</idno></analytic><monogr><title level="j">Pediatric Nephrology</title><title level="j" type="sub">Journal of the International Pediatric Nephrology Association</title><title level="j" type="abbrev">Pediatr Nephrol</title><idno type="pISSN">0931-041X</idno><idno type="eISSN">1432-198X</idno><idno type="journal-ID">true</idno><idno type="issue-article-count">34</idno><idno type="volume-issue-count">12</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="2006-08-01"></date><biblScope unit="volume">21</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="1200">1200</biblScope><biblScope unit="page" to="1205">1205</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2005-09-19</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: Hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by recurrent skin abscesses, recurrent pneumonia with pneumatocele formation, eczema, eosinophilia, and elevated levels of serum IgE. Patients with the autosomal recessive (AR) form of HIES appear to be prone to developing autoimmune diseases. We present two cases of HIES with autoimmune complications; one case was a product of a consanguineous marriage, the other one was a sporadic case. The first patient presented with recurrent episodes of erythema nodosum, warts, bronchiolitis obliterans and thrombocytopenia. The second patient developed glomerulonephritis resulting in endstage renal failure. She later developed malar rash, oral ulcers, cerebral infarcts with vasculitis and positive ANA, anti-dsDNA, and antiphospholipid antibodies. We discuss the dilemma in treating patients who present with both primary immunodeficiency and autoimmunity.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Systemic lupus erythematosus</term></item><item><term>Antiphospholipid syndrome</term></item><item><term>Hyper-IgE syndrome</term></item><item><term>Autoimmunity</term></item><item><term>Primary immunodeficiency</term></item><item><term>CNS vasculitis</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>Medicine & Public Health</head><item><term>Pediatrics</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2005-09-19">Created</change><change when="2006-08-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-R7NHRMND-S/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus springer-journals not found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Springer-Verlag</PublisherName><PublisherLocation>Berlin/Heidelberg</PublisherLocation></PublisherInfo><Journal OutputMedium="All"><JournalInfo JournalProductType="ArchiveJournal" NumberingStyle="Unnumbered"><JournalID>467</JournalID><JournalPrintISSN>0931-041X</JournalPrintISSN><JournalElectronicISSN>1432-198X</JournalElectronicISSN><JournalTitle>Pediatric Nephrology</JournalTitle><JournalSubTitle>Journal of the International
Pediatric Nephrology Association</JournalSubTitle><JournalAbbreviatedTitle>Pediatr Nephrol</JournalAbbreviatedTitle><JournalSubjectGroup><JournalSubject Type="Primary">Medicine & Public Health</JournalSubject><JournalSubject Type="Secondary">Pediatrics </JournalSubject></JournalSubjectGroup></JournalInfo><Volume OutputMedium="All"><VolumeInfo TocLevels="0" VolumeType="Regular"><VolumeIDStart>21</VolumeIDStart><VolumeIDEnd>21</VolumeIDEnd><VolumeIssueCount>12</VolumeIssueCount></VolumeInfo><Issue IssueType="Regular" OutputMedium="All"><IssueInfo TocLevels="0"><IssueIDStart>8</IssueIDStart><IssueIDEnd>8</IssueIDEnd><IssueArticleCount>34</IssueArticleCount><IssueHistory><OnlineDate><Year>2006</Year><Month>7</Month><Day>18</Day></OnlineDate><PrintDate><Year>2006</Year><Month>7</Month><Day>18</Day></PrintDate><CoverDate><Year>2006</Year><Month>8</Month></CoverDate></IssueHistory><IssueCopyright><CopyrightHolderName>IPNA</CopyrightHolderName><CopyrightYear>2006</CopyrightYear></IssueCopyright></IssueInfo><Article ID="s00467-006-0178-3" OutputMedium="All"><ArticleInfo ArticleType="BriefCommunication" ContainsESM="No" Language="En" NumberingStyle="Unnumbered" TocLevels="0"><ArticleID>178</ArticleID><ArticleDOI>10.1007/s00467-006-0178-3</ArticleDOI><ArticleSequenceNumber>25</ArticleSequenceNumber><ArticleTitle Language="En">Hyper-IgE syndrome and autoimmunity in Mexican children</ArticleTitle><ArticleCategory>Brief Report</ArticleCategory><ArticleFirstPage>1200</ArticleFirstPage><ArticleLastPage>1205</ArticleLastPage><ArticleHistory><RegistrationDate><Year>2006</Year><Month>4</Month><Day>27</Day></RegistrationDate><Received><Year>2005</Year><Month>9</Month><Day>19</Day></Received><Revised><Year>2006</Year><Month>3</Month><Day>28</Day></Revised><Accepted><Year>2006</Year><Month>3</Month><Day>31</Day></Accepted><OnlineDate><Year>2006</Year><Month>6</Month><Day>22</Day></OnlineDate></ArticleHistory><ArticleCopyright><CopyrightHolderName>IPNA</CopyrightHolderName><CopyrightYear>2006</CopyrightYear></ArticleCopyright><ArticleGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Marco</GivenName><FamilyName>Yamazaki-Nakashimada</FamilyName></AuthorName><Contact><Email>yzki71@yahoo.com.mx</Email></Contact></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>Samuel</GivenName><FamilyName>Zaltzman-Girshevich</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>Silvestre</GivenName><FamilyName>Garcia de la Puente</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff3"><AuthorName DisplayOrder="Western"><GivenName>Beatriz</GivenName><Particle>De</Particle><FamilyName>Leon-Bojorge</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Sara</GivenName><FamilyName>Espinosa-Padilla</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff4"><AuthorName DisplayOrder="Western"><GivenName>Marimar</GivenName><FamilyName>Saez-de-Ocariz</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff3"><AuthorName DisplayOrder="Western"><GivenName>Daniel</GivenName><FamilyName>Carrasco-Daza</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Victor</GivenName><FamilyName>Hernandez-Bautista</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff5"><AuthorName DisplayOrder="Western"><GivenName>Lorenzo</GivenName><FamilyName>Pérez-Fernandez</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Francisco</GivenName><FamilyName>Espinosa-Rosales</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Department of Clinical Immunology</OrgDivision><OrgName>Instituto Nacional de Pediatría</OrgName><OrgAddress><Street>Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco</Street><City>Mexico City</City><Country Code="MX">Mexico</Country></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgDivision>Department of Nephrology</OrgDivision><OrgName>Instituto Nacional de Pediatría</OrgName><OrgAddress><Street>Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco</Street><City>Mexico City</City><Country Code="MX">Mexico</Country></OrgAddress></Affiliation><Affiliation ID="Aff3"><OrgDivision>Department of Pathology</OrgDivision><OrgName>Instituto Nacional de Pediatría</OrgName><OrgAddress><Street>Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco</Street><City>Mexico City</City><Country Code="MX">Mexico</Country></OrgAddress></Affiliation><Affiliation ID="Aff4"><OrgDivision>Department of Dermatology</OrgDivision><OrgName>Instituto Nacional de Pediatría</OrgName><OrgAddress><Street>Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco</Street><City>Mexico City</City><Country Code="MX">Mexico</Country></OrgAddress></Affiliation><Affiliation ID="Aff5"><OrgDivision>Department of Pulmonology</OrgDivision><OrgName>Instituto Nacional de Pediatría</OrgName><OrgAddress><Street>Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco</Street><City>Mexico City</City><Country Code="MX">Mexico</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para>Hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by recurrent skin abscesses, recurrent pneumonia with pneumatocele formation, eczema, eosinophilia, and elevated levels of serum IgE. Patients with the autosomal recessive (AR) form of HIES appear to be prone to developing autoimmune diseases. We present two cases of HIES with autoimmune complications; one case was a product of a consanguineous marriage, the other one was a sporadic case. The first patient presented with recurrent episodes of erythema nodosum, warts, bronchiolitis obliterans and thrombocytopenia. The second patient developed glomerulonephritis resulting in endstage renal failure. She later developed malar rash, oral ulcers, cerebral infarcts with vasculitis and positive ANA, anti-dsDNA, and antiphospholipid antibodies. We discuss the dilemma in treating patients who present with both primary immunodeficiency and autoimmunity.</Para></Abstract><KeywordGroup Language="En"><Heading>Keywords</Heading><Keyword>Systemic lupus erythematosus</Keyword><Keyword>Antiphospholipid syndrome</Keyword><Keyword>Hyper-IgE syndrome</Keyword><Keyword>Autoimmunity</Keyword><Keyword>Primary immunodeficiency</Keyword><Keyword>CNS vasculitis</Keyword></KeywordGroup></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Hyper-IgE syndrome and autoimmunity in Mexican children</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Hyper-IgE syndrome and autoimmunity in Mexican children</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Marco</namePart><namePart type="family">Yamazaki-Nakashimada</namePart><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><affiliation>E-mail: yzki71@yahoo.com.mx</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Samuel</namePart><namePart type="family">Zaltzman-Girshevich</namePart><affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Silvestre</namePart><namePart type="family">Garcia de la Puente</namePart><affiliation>Department of Nephrology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Beatriz</namePart><namePart type="family">De Leon-Bojorge</namePart><affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Sara</namePart><namePart type="family">Espinosa-Padilla</namePart><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marimar</namePart><namePart type="family">Saez-de-Ocariz</namePart><affiliation>Department of Dermatology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Daniel</namePart><namePart type="family">Carrasco-Daza</namePart><affiliation>Department of Pathology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Victor</namePart><namePart type="family">Hernandez-Bautista</namePart><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Lorenzo</namePart><namePart type="family">Pérez-Fernandez</namePart><affiliation>Department of Pulmonology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Francisco</namePart><namePart type="family">Espinosa-Rosales</namePart><affiliation>Department of Clinical Immunology, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Mexico City, Mexico</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="brief-communication" displayLabel="BriefCommunication" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-S9SX2MFS-0">brief-communication</genre><originInfo><publisher>Springer-Verlag</publisher><place><placeTerm type="text">Berlin/Heidelberg</placeTerm></place><dateCreated encoding="w3cdtf">2005-09-19</dateCreated><dateIssued encoding="w3cdtf">2006-08-01</dateIssued><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by recurrent skin abscesses, recurrent pneumonia with pneumatocele formation, eczema, eosinophilia, and elevated levels of serum IgE. Patients with the autosomal recessive (AR) form of HIES appear to be prone to developing autoimmune diseases. We present two cases of HIES with autoimmune complications; one case was a product of a consanguineous marriage, the other one was a sporadic case. The first patient presented with recurrent episodes of erythema nodosum, warts, bronchiolitis obliterans and thrombocytopenia. The second patient developed glomerulonephritis resulting in endstage renal failure. She later developed malar rash, oral ulcers, cerebral infarcts with vasculitis and positive ANA, anti-dsDNA, and antiphospholipid antibodies. We discuss the dilemma in treating patients who present with both primary immunodeficiency and autoimmunity.</abstract><note>Brief Report</note><subject lang="en"><genre>Keywords</genre><topic>Systemic lupus erythematosus</topic><topic>Antiphospholipid syndrome</topic><topic>Hyper-IgE syndrome</topic><topic>Autoimmunity</topic><topic>Primary immunodeficiency</topic><topic>CNS vasculitis</topic></subject><relatedItem type="host"><titleInfo><title>Pediatric Nephrology</title><subTitle>Journal of the International Pediatric Nephrology Association</subTitle></titleInfo><titleInfo type="abbreviated"><title>Pediatr Nephrol</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>Springer</publisher><dateIssued encoding="w3cdtf">2006-07-18</dateIssued><copyrightDate encoding="w3cdtf">2006</copyrightDate></originInfo><subject><genre>Medicine & Public Health</genre><topic>Pediatrics</topic></subject><identifier type="ISSN">0931-041X</identifier><identifier type="eISSN">1432-198X</identifier><identifier type="JournalID">467</identifier><identifier type="IssueArticleCount">34</identifier><identifier type="VolumeIssueCount">12</identifier><part><date>2006</date><detail type="volume"><number>21</number><caption>vol.</caption></detail><detail type="issue"><number>8</number><caption>no.</caption></detail><extent unit="pages"><start>1200</start><end>1205</end></extent></part><recordInfo><recordOrigin>IPNA, 2006</recordOrigin></recordInfo></relatedItem><identifier type="istex">E4BE8B4C919BB11C12FE2244E7B435CE7FC58112</identifier><identifier type="ark">ark:/67375/VQC-R7NHRMND-S</identifier><identifier type="DOI">10.1007/s00467-006-0178-3</identifier><identifier type="ArticleID">178</identifier><identifier type="ArticleID">s00467-006-0178-3</identifier><accessCondition type="use and reproduction" contentType="copyright">IPNA, 2006</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</recordContentSource><recordOrigin>IPNA, 2006</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-R7NHRMND-S/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002644 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 002644 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:E4BE8B4C919BB11C12FE2244E7B435CE7FC58112
|texte= Hyper-IgE syndrome and autoimmunity in Mexican children
}}
| This area was generated with Dilib version V0.6.33. |  |